JPWO2022218891A5 - - Google Patents

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Publication number
JPWO2022218891A5
JPWO2022218891A5 JP2024505491A JP2024505491A JPWO2022218891A5 JP WO2022218891 A5 JPWO2022218891 A5 JP WO2022218891A5 JP 2024505491 A JP2024505491 A JP 2024505491A JP 2024505491 A JP2024505491 A JP 2024505491A JP WO2022218891 A5 JPWO2022218891 A5 JP WO2022218891A5
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JP
Japan
Prior art keywords
alkylene
composition
alkyl
independently selected
mol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024505491A
Other languages
English (en)
Japanese (ja)
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JP2024514364A (ja
JP2024514364A5 (https=
Publication date
Priority claimed from PCT/EP2021/059460 external-priority patent/WO2022218503A1/en
Application filed filed Critical
Priority claimed from PCT/EP2022/059555 external-priority patent/WO2022218891A2/en
Publication of JP2024514364A publication Critical patent/JP2024514364A/ja
Publication of JPWO2022218891A5 publication Critical patent/JPWO2022218891A5/ja
Publication of JP2024514364A5 publication Critical patent/JP2024514364A5/ja
Pending legal-status Critical Current

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JP2024505491A 2021-04-12 2022-04-11 緩衝物質を含むrna組成物ならびにその製造、保存および使用のための方法 Pending JP2024514364A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EPPCT/EP2021/059460 2021-04-12
PCT/EP2021/059460 WO2022218503A1 (en) 2021-04-12 2021-04-12 Lnp compositions comprising rna and methods for preparing, storing and using the same
EPPCT/EP2021/087882 2021-12-30
EP2021087882 2021-12-30
PCT/EP2022/059555 WO2022218891A2 (en) 2021-04-12 2022-04-11 Rna compositions comprising a buffer substance and methods for preparing, storing and using the same

Publications (3)

Publication Number Publication Date
JP2024514364A JP2024514364A (ja) 2024-04-01
JPWO2022218891A5 true JPWO2022218891A5 (https=) 2025-04-17
JP2024514364A5 JP2024514364A5 (https=) 2025-04-17

Family

ID=81393053

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024505491A Pending JP2024514364A (ja) 2021-04-12 2022-04-11 緩衝物質を含むrna組成物ならびにその製造、保存および使用のための方法

Country Status (6)

Country Link
US (1) US20240226132A1 (https=)
EP (1) EP4322925A2 (https=)
JP (1) JP2024514364A (https=)
AU (1) AU2022256732A1 (https=)
CA (1) CA3215103A1 (https=)
WO (1) WO2022218891A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024089229A1 (en) * 2022-10-28 2024-05-02 CureVac SE Improved formulations comprising lipid-based carriers encapsulating rna

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US20050287153A1 (en) 2002-06-28 2005-12-29 Genentech, Inc. Serum albumin binding peptides for tumor targeting
PT1309726E (pt) 2000-03-30 2010-03-08 Whitehead Biomedical Inst Mediadores de interferência por rna específicos de sequência de rna
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
US7696320B2 (en) 2004-08-24 2010-04-13 Domantis Limited Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
ES2655912T3 (es) 2002-11-08 2018-02-22 Ablynx N.V. Anticuerpos de dominio simple dirigidos contra factor de necrosis tumoral-alfa y usos para los mismos
ES2567634T3 (es) 2004-02-09 2016-04-25 Human Genome Sciences, Inc. Proteínas de fusión de albúmina
DE102005046490A1 (de) 2005-09-28 2007-03-29 Johannes-Gutenberg-Universität Mainz Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
US20070269422A1 (en) 2006-05-17 2007-11-22 Ablynx N.V. Serum albumin binding proteins with long half-lives
WO2008012629A2 (en) 2006-07-24 2008-01-31 Biorexis Pharmaceutical Corporation Exendin fusion proteins
CN101646689A (zh) 2006-09-08 2010-02-10 埃博灵克斯股份有限公司 具有长半衰期的血清清蛋白结合蛋白
JP2011507543A (ja) 2007-12-27 2011-03-10 ノバルティス アーゲー 改善されたフィブロネクチンベースの結合分子およびそれらの使用
PL2274331T3 (pl) 2008-05-02 2014-04-30 Novartis Ag Ulepszone cząsteczki wiążące oparte na fibronektynie i ich zastosowanie
US10233228B2 (en) 2010-04-09 2019-03-19 Albumedix Ltd Albumin derivatives and variants
EA022983B1 (ru) 2010-04-13 2016-04-29 Бристол-Майерс Сквибб Компани Белки на основе структурного домена фибронектина, связывающие pcsk9
US20140220017A1 (en) 2011-09-23 2014-08-07 Universitat Stuttgart Serum half-life extension using igbd
EP2780364A2 (en) 2011-11-18 2014-09-24 Eleven Biotherapeutics, Inc. Proteins with improved half-life and other properties
FR3009192B1 (fr) 2013-07-31 2015-09-04 Oreal Composition cosmetique anhydre comprenant de l'alkylcellulose, au moins un ester ramifie de dextrine et au moins un alcool gras
WO2016005004A1 (en) 2014-07-11 2016-01-14 Biontech Rna Pharmaceuticals Gmbh Stabilization of poly(a) sequence encoding dna sequences
US11219634B2 (en) * 2015-01-21 2022-01-11 Genevant Sciences Gmbh Methods, compositions, and systems for delivering therapeutic and diagnostic agents into cells
US20180303925A1 (en) 2015-04-27 2018-10-25 The Trustees Of The University Of Pennsylvania Nucleoside-Modified RNA For Inducing an Adaptive Immune Response
IL307179A (en) 2015-10-28 2023-11-01 Acuitas Therapeutics Inc Novel lipids and lipid nanoparticle formulations for delivery of nucleic acids
BR112018069417A2 (pt) 2016-04-22 2019-01-22 Biontech Rna Pharmaceuticals Gmbh método para fornecer rna fita simples e ssrna
WO2017218704A1 (en) * 2016-06-14 2017-12-21 Modernatx, Inc. Stabilized formulations of lipid nanoparticles
BR112019008481A2 (pt) * 2016-10-26 2020-03-03 Curevac Ag Vacinas de mrna de nanopartículas lipídicas
ES3063077T3 (en) 2016-10-26 2026-04-15 Acuitas Therapeutics Inc Lipid nanoparticle formulations

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