JP2023549265A5 - - Google Patents

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Publication number
JP2023549265A5
JP2023549265A5 JP2023528665A JP2023528665A JP2023549265A5 JP 2023549265 A5 JP2023549265 A5 JP 2023549265A5 JP 2023528665 A JP2023528665 A JP 2023528665A JP 2023528665 A JP2023528665 A JP 2023528665A JP 2023549265 A5 JP2023549265 A5 JP 2023549265A5
Authority
JP
Japan
Prior art keywords
concentration
approximately
formulation according
lipids
sodium chloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023528665A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023549265A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/081674 external-priority patent/WO2022101469A1/en
Publication of JP2023549265A publication Critical patent/JP2023549265A/ja
Publication of JP2023549265A5 publication Critical patent/JP2023549265A5/ja
Pending legal-status Critical Current

Links

JP2023528665A 2020-11-16 2021-11-15 脂質ナノ粒子mRNAワクチンの安定化のための組成物および方法 Pending JP2023549265A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063114478P 2020-11-16 2020-11-16
US63/114,478 2020-11-16
US202063115588P 2020-11-18 2020-11-18
US63/115,588 2020-11-18
PCT/EP2021/081674 WO2022101469A1 (en) 2020-11-16 2021-11-15 Compositions and methods for stabilization of lipid nanoparticle mrna vaccines

Publications (2)

Publication Number Publication Date
JP2023549265A JP2023549265A (ja) 2023-11-22
JP2023549265A5 true JP2023549265A5 (https=) 2026-04-27

Family

ID=78770624

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023528665A Pending JP2023549265A (ja) 2020-11-16 2021-11-15 脂質ナノ粒子mRNAワクチンの安定化のための組成物および方法

Country Status (9)

Country Link
US (1) US20240041785A1 (https=)
EP (1) EP4243789A1 (https=)
JP (1) JP2023549265A (https=)
KR (1) KR20230109689A (https=)
AU (1) AU2021380033A1 (https=)
CA (1) CA3198311A1 (https=)
IL (1) IL302770A (https=)
MX (1) MX2023005697A (https=)
WO (1) WO2022101469A1 (https=)

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Publication number Priority date Publication date Assignee Title
MA42543A (fr) 2015-07-30 2018-06-06 Modernatx Inc Arn épitope peptidiques concatémériques
EP4011451A1 (en) 2015-10-22 2022-06-15 ModernaTX, Inc. Metapneumovirus mrna vaccines
MA46766A (fr) 2016-11-11 2019-09-18 Modernatx Inc Vaccin antigrippal
WO2018170245A1 (en) 2017-03-15 2018-09-20 Modernatx, Inc. Broad spectrum influenza virus vaccine
US11905525B2 (en) 2017-04-05 2024-02-20 Modernatx, Inc. Reduction of elimination of immune responses to non-intravenous, e.g., subcutaneously administered therapeutic proteins
EP3746090A4 (en) 2018-01-29 2021-11-17 ModernaTX, Inc. RSV RNA Vaccines
IL297419B2 (en) 2020-04-22 2025-02-01 BioNTech SE Coronavirus vaccine
CZ310613B6 (cs) 2020-09-23 2026-01-28 Ústav organické chemie a biochemie AV ČR, v. v. i. Lipidoidy pro transfekci nukleových kyselin a jejich použití
WO2022232585A1 (en) * 2021-04-29 2022-11-03 Modernatx, Inc. Lyophilization methods for preparing lipid formulated therapeutics
CZ310443B6 (cs) 2021-07-19 2025-06-25 Ústav organické chemie a biochemie AV ČR, v. v. i. Cyklohexanové lipidoidy pro transfekci nukleových kyselin a jejich použití
US12186387B2 (en) 2021-11-29 2025-01-07 BioNTech SE Coronavirus vaccine
WO2024002985A1 (en) 2022-06-26 2024-01-04 BioNTech SE Coronavirus vaccine
WO2024081639A1 (en) * 2022-10-11 2024-04-18 Seawolf Therapeutics, Inc. Novel lipid nanoparticle compositions for the delivery of nucleic acids
WO2024089634A1 (en) * 2022-10-27 2024-05-02 Pfizer Inc. Immunogenic compositions against influenza and rsv
IL320459A (en) * 2022-10-27 2025-06-01 Pfizer Rna molecules encoding rsv-f and vaccines containing them
JP2026500218A (ja) * 2022-12-11 2026-01-06 ファイザー・インク インフルエンザおよびrsvに対する免疫原性組成物
CN116139108B (zh) * 2023-04-23 2023-08-01 威瑞生物科技(昆明)有限责任公司 一种脂质递送系统及其所构成的类病毒结构疫苗
CN119101681A (zh) * 2023-06-09 2024-12-10 仁景(苏州)生物科技有限公司 表达可调控的工程化rna分子
WO2025038371A1 (en) * 2023-08-11 2025-02-20 Purdue Research Foundation Salt-loaded solid lipid nanoparticles loaded with an active agent
WO2025077899A1 (zh) * 2023-10-13 2025-04-17 北京先声祥瑞生物制品股份有限公司 一种核酸药物冻干制剂及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101766408B1 (ko) * 2009-06-10 2017-08-10 알닐람 파마슈티칼스 인코포레이티드 향상된 지질 조성물
WO2016005004A1 (en) 2014-07-11 2016-01-14 Biontech Rna Pharmaceuticals Gmbh Stabilization of poly(a) sequence encoding dna sequences
HRP20230209T1 (hr) * 2015-10-28 2023-04-14 Acuitas Therapeutics Inc. Novi lipidi i lipidne formulacije nanočestica za isporuku nukleinskih kiselina
WO2017218704A1 (en) * 2016-06-14 2017-12-21 Modernatx, Inc. Stabilized formulations of lipid nanoparticles
CA3040337A1 (en) * 2016-10-26 2018-05-03 Curevac Ag Lipid nanoparticle mrna vaccines
US20220009878A1 (en) * 2018-10-02 2022-01-13 Intellia Therapeutics, Inc. Ionizable amine lipids
JP2023511633A (ja) * 2020-01-28 2023-03-20 モデルナティエックス インコーポレイテッド コロナウイルスrnaワクチン

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