DE69528170T2 - Intrazelluläre verabreichung therapeutischer sustanzenmittels virosomen - Google Patents
Intrazelluläre verabreichung therapeutischer sustanzenmittels virosomenInfo
- Publication number
- DE69528170T2 DE69528170T2 DE69528170T DE69528170T DE69528170T2 DE 69528170 T2 DE69528170 T2 DE 69528170T2 DE 69528170 T DE69528170 T DE 69528170T DE 69528170 T DE69528170 T DE 69528170T DE 69528170 T2 DE69528170 T2 DE 69528170T2
- Authority
- DE
- Germany
- Prior art keywords
- virosomes
- therapeutic substances
- intracellular administration
- therapeutic compounds
- intracellular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5176—Compounds of unknown constitution, e.g. material from plants or animals
- A61K9/5184—Virus capsids or envelopes enclosing drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Optics & Photonics (AREA)
- Botany (AREA)
- Nanotechnology (AREA)
- Dispersion Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25146994A | 1994-05-31 | 1994-05-31 | |
PCT/CA1995/000321 WO1995032706A1 (en) | 1994-05-31 | 1995-05-31 | Virosome-mediated intracellular delivery of therapeutic agents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69528170D1 DE69528170D1 (de) | 2002-10-17 |
DE69528170T2 true DE69528170T2 (de) | 2003-05-22 |
Family
ID=22952103
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69528170T Expired - Lifetime DE69528170T2 (de) | 1994-05-31 | 1995-05-31 | Intrazelluläre verabreichung therapeutischer sustanzenmittels virosomen |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0762870B1 (de) |
JP (1) | JPH10505320A (de) |
AT (1) | ATE223701T1 (de) |
AU (1) | AU2520595A (de) |
CA (1) | CA2191750C (de) |
DE (1) | DE69528170T2 (de) |
WO (1) | WO1995032706A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0850064A1 (de) * | 1995-09-14 | 1998-07-01 | Lxr Biotechnology Inc. | Anti-apoptose zusammensetzung die eine mischung von phospholipiden enthält |
NZ332666A (en) * | 1996-05-08 | 2000-05-26 | Nika Health Products Ltd | Cationic virosomes having a positively charged lipid bilayer membrane with an integrated viral fusogenic peptide as genetic transfer systems for use in gene therapy |
US7470426B1 (en) | 1997-10-09 | 2008-12-30 | Wellstat Biologics Corporation | Treatment of neoplasms with viruses |
US7780962B2 (en) | 1997-10-09 | 2010-08-24 | Wellstat Biologics Corporation | Treatment of neoplasms with RNA viruses |
US20030044384A1 (en) | 1997-10-09 | 2003-03-06 | Pro-Virus, Inc. | Treatment of neoplasms with viruses |
EP1390046A4 (de) | 1999-04-15 | 2005-04-20 | Wellstat Biologics Corp | Behandlung von neoplasmen mit viren |
US8147822B1 (en) | 1999-09-17 | 2012-04-03 | Wellstat Biologics Corporation | Oncolytic virus |
JP4497894B2 (ja) * | 2003-11-07 | 2010-07-07 | 明彦 河合 | 物質導入剤およびその製造方法 |
EP1773303A2 (de) | 2004-05-25 | 2007-04-18 | Chimeracore, Inc. | Selbstmontierendes nanopartikel-wirkstofffreisetzungssystem |
PL1802746T3 (pl) | 2004-10-27 | 2011-10-31 | Crucell Switzerland Ag | Cząstki wirosomu zawierające antygeny wirusa grypy i wirusa zapalenia wątroby typu B |
JP2009533350A (ja) * | 2006-04-07 | 2009-09-17 | キメロス, インコーポレイテッド | B細胞悪性疾患を処置するための組成物および方法 |
WO2010120874A2 (en) | 2009-04-14 | 2010-10-21 | Chimeros, Inc. | Chimeric therapeutics, compositions, and methods for using same |
EP2747774A4 (de) | 2011-09-09 | 2015-02-11 | Biomed Realty L P | Verfahren und zusammensetzungen zur kontrolle einer virusproteinassemblierung |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9018690D0 (en) * | 1990-08-24 | 1990-10-10 | Wellcome Found | Vaccines |
PL296382A1 (en) * | 1991-02-02 | 1993-11-02 | Nika Health Products Ltd Li Li | Artificial membrane beads containing functionally active peptides responsible for fusion as a drug administering system |
US5292524A (en) * | 1991-09-06 | 1994-03-08 | California Institute Of Technology | Blood platelet loaded with diagnostic or therapeutic-containing liposome or reconstituted Sendai virus |
-
1995
- 1995-05-31 WO PCT/CA1995/000321 patent/WO1995032706A1/en active IP Right Grant
- 1995-05-31 DE DE69528170T patent/DE69528170T2/de not_active Expired - Lifetime
- 1995-05-31 JP JP8500118A patent/JPH10505320A/ja active Pending
- 1995-05-31 AT AT95919296T patent/ATE223701T1/de not_active IP Right Cessation
- 1995-05-31 CA CA002191750A patent/CA2191750C/en not_active Expired - Fee Related
- 1995-05-31 AU AU25205/95A patent/AU2520595A/en not_active Abandoned
- 1995-05-31 EP EP95919296A patent/EP0762870B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0762870A1 (de) | 1997-03-19 |
ATE223701T1 (de) | 2002-09-15 |
DE69528170D1 (de) | 2002-10-17 |
AU2520595A (en) | 1995-12-21 |
JPH10505320A (ja) | 1998-05-26 |
CA2191750C (en) | 2008-06-10 |
WO1995032706A1 (en) | 1995-12-07 |
CA2191750A1 (en) | 1995-12-07 |
EP0762870B1 (de) | 2002-09-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: UNIVERSITY OF GRONINGEN,FACULTY OF MEDICAL SCIENCE |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: BESTEWIL HOLDING B.V., AMSTERDAM, NL |
|
8364 | No opposition during term of opposition |