JPWO2022101486A5 - - Google Patents
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- Publication number
- JPWO2022101486A5 JPWO2022101486A5 JP2023528680A JP2023528680A JPWO2022101486A5 JP WO2022101486 A5 JPWO2022101486 A5 JP WO2022101486A5 JP 2023528680 A JP2023528680 A JP 2023528680A JP 2023528680 A JP2023528680 A JP 2023528680A JP WO2022101486 A5 JPWO2022101486 A5 JP WO2022101486A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- lipid
- formulation
- cryoprotectant
- mrna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063114478P | 2020-11-16 | 2020-11-16 | |
| US63/114,478 | 2020-11-16 | ||
| EP2020082602 | 2020-11-18 | ||
| EPPCT/EP2020/082602 | 2020-11-18 | ||
| PCT/EP2021/081741 WO2022101486A1 (en) | 2020-11-16 | 2021-11-15 | Pharmaceutical compositions comprising particles and mrna and methods for preparing and storing the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023552678A JP2023552678A (ja) | 2023-12-19 |
| JPWO2022101486A5 true JPWO2022101486A5 (https=) | 2024-11-22 |
| JP2023552678A5 JP2023552678A5 (https=) | 2024-11-22 |
Family
ID=78617419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023528680A Pending JP2023552678A (ja) | 2020-11-16 | 2021-11-15 | 粒子およびｍＲＮＡを含む医薬組成物ならびにそれを調製および貯蔵する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240033344A1 (https=) |
| EP (1) | EP4243787A1 (https=) |
| JP (1) | JP2023552678A (https=) |
| AU (1) | AU2021377746A1 (https=) |
| CA (1) | CA3198309A1 (https=) |
| WO (2) | WO2022101486A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2021379090A1 (en) * | 2020-11-16 | 2023-06-15 | BioNTech SE | Lnp compositions comprising rna and methods for preparing, storing and using the same |
| US11524023B2 (en) * | 2021-02-19 | 2022-12-13 | Modernatx, Inc. | Lipid nanoparticle compositions and methods of formulating the same |
| CN114989182B (zh) * | 2022-06-23 | 2023-06-23 | 尧唐(上海)生物科技有限公司 | 脂质化合物、包含其的组合物及应用 |
| WO2024006863A1 (en) * | 2022-06-30 | 2024-01-04 | Precision NanoSystems ULC | Lipid nanoparticle formulations for vaccines |
| CN115869394A (zh) * | 2022-07-21 | 2023-03-31 | 中国食品药品检定研究院 | 核酸佐剂、含有所述核酸佐剂的疫苗及应用 |
| IL321279A (en) * | 2022-12-23 | 2025-08-01 | Lilly Co Eli | Stabilization of lipid nanoparticle formulations |
| WO2024160826A1 (en) * | 2023-01-31 | 2024-08-08 | BioNTech SE | Compositions and methods |
| US11833224B1 (en) * | 2023-02-08 | 2023-12-05 | Leuvian Llc | Lyoprotectant compositions and uses thereof |
| KR20250153298A (ko) * | 2023-03-08 | 2025-10-24 | 큐어백 에스이 | 핵산 전달을 위한 신규의 지질 나노입자 제형 |
| WO2024193827A1 (en) * | 2023-03-23 | 2024-09-26 | BioNTech SE | Stabilized nucleic acid compositions and methods for preparing, storing and using the same |
| EP4442256A1 (en) * | 2023-04-04 | 2024-10-09 | Københavns Universitet | Lipid nanoparticle compositions |
| TW202446402A (zh) * | 2023-04-12 | 2024-12-01 | 美商艾拉倫製藥公司 | 用於寡核苷酸遞送之調配物 |
| US12311033B2 (en) | 2023-05-31 | 2025-05-27 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| AU2023457271A1 (en) * | 2023-06-28 | 2025-12-18 | Global Life Sciences Solutions Canada Ulc | Lipid nanoparticle formulations for cell therapy and related methods |
| CN121712495A (zh) * | 2023-08-21 | 2026-03-20 | 环球生命科学解决方案加拿大有限公司 | 用于离子流脂质纳米颗粒的制造方法和装置 |
| WO2025061153A1 (en) * | 2023-09-22 | 2025-03-27 | Everest Medicines (China) Co., Ltd. | Rna-lipid particles comprising polysarcosine-lipid conjugate |
| WO2025087303A1 (en) * | 2023-10-24 | 2025-05-01 | Mote Therapeutics Inc. | Lipid nanoparticle with non-covalent bifunctional binders for active targeting |
| WO2025133105A1 (en) * | 2023-12-21 | 2025-06-26 | Biontech Delivery Technologies Gmbh | Compositions and methods |
| WO2025176732A1 (en) | 2024-02-20 | 2025-08-28 | BioNTech SE | Compositions and methods |
| WO2025261607A1 (en) | 2024-06-21 | 2025-12-26 | BioNTech SE | Particles, compositions and methods |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| ES2707966T3 (es) * | 2013-10-22 | 2019-04-08 | Translate Bio Inc | Terapia de ARNm para la deficiencia en síntesis de argininosuccinato |
| WO2016005004A1 (en) | 2014-07-11 | 2016-01-14 | Biontech Rna Pharmaceuticals Gmbh | Stabilization of poly(a) sequence encoding dna sequences |
| SG11201707663SA (en) * | 2015-04-17 | 2017-11-29 | Curevac Ag | Lyophilization of rna |
| US20180303925A1 (en) | 2015-04-27 | 2018-10-25 | The Trustees Of The University Of Pennsylvania | Nucleoside-Modified RNA For Inducing an Adaptive Immune Response |
| IL307179A (en) * | 2015-10-28 | 2023-11-01 | Acuitas Therapeutics Inc | Novel lipids and lipid nanoparticle formulations for delivery of nucleic acids |
| BR112018069417A2 (pt) | 2016-04-22 | 2019-01-22 | Biontech Rna Pharmaceuticals Gmbh | método para fornecer rna fita simples e ssrna |
| WO2017218704A1 (en) * | 2016-06-14 | 2017-12-21 | Modernatx, Inc. | Stabilized formulations of lipid nanoparticles |
| BR112019008481A2 (pt) * | 2016-10-26 | 2020-03-03 | Curevac Ag | Vacinas de mrna de nanopartículas lipídicas |
| WO2020072605A1 (en) * | 2018-10-02 | 2020-04-09 | Intellia Therapeutics, Inc. | Ionizable amine lipids |
-
2021
- 2021-11-15 US US18/036,681 patent/US20240033344A1/en active Pending
- 2021-11-15 WO PCT/EP2021/081741 patent/WO2022101486A1/en not_active Ceased
- 2021-11-15 WO PCT/EP2021/081676 patent/WO2022101471A1/en not_active Ceased
- 2021-11-15 CA CA3198309A patent/CA3198309A1/en active Pending
- 2021-11-15 AU AU2021377746A patent/AU2021377746A1/en active Pending
- 2021-11-15 EP EP21806755.1A patent/EP4243787A1/en active Pending
- 2021-11-15 JP JP2023528680A patent/JP2023552678A/ja active Pending
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