|
NL154598B
(nl)
|
1970-11-10 |
1977-09-15 |
Organon Nv |
Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
|
|
US3817837A
(en)
|
1971-05-14 |
1974-06-18 |
Syva Corp |
Enzyme amplification assay
|
|
US4277437A
(en)
|
1978-04-05 |
1981-07-07 |
Syva Company |
Kit for carrying out chemically induced fluorescence immunoassay
|
|
US4275149A
(en)
|
1978-11-24 |
1981-06-23 |
Syva Company |
Macromolecular environment control in specific receptor assays
|
|
US4366241A
(en)
|
1980-08-07 |
1982-12-28 |
Syva Company |
Concentrating zone method in heterogeneous immunoassays
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
|
US4737456A
(en)
|
1985-05-09 |
1988-04-12 |
Syntex (U.S.A.) Inc. |
Reducing interference in ligand-receptor binding assays
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
IL162181A
(en)
|
1988-12-28 |
2006-04-10 |
Pdl Biopharma Inc |
A method of producing humanized immunoglubulin, and polynucleotides encoding the same
|
|
FR2646437B1
(fr)
|
1989-04-28 |
1991-08-30 |
Transgene Sa |
Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5264618A
(en)
|
1990-04-19 |
1993-11-23 |
Vical, Inc. |
Cationic lipids for intracellular delivery of biologically active molecules
|
|
AU7979491A
(en)
|
1990-05-03 |
1991-11-27 |
Vical, Inc. |
Intracellular delivery of biologically active substances by means of self-assembling lipid complexes
|
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
|
ES2108048T3
(es)
|
1990-08-29 |
1997-12-16 |
Genpharm Int |
Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos.
|
|
AU2235992A
(en)
|
1991-06-14 |
1993-01-12 |
Genpharm International, Inc. |
Transgenic immunodeficient non-human animals
|
|
EP0940468A1
(en)
|
1991-06-14 |
1999-09-08 |
Genentech, Inc. |
Humanized antibody variable domain
|
|
JPH06508880A
(ja)
|
1991-07-08 |
1994-10-06 |
ユニバーシティ オブ マサチューセッツ アット アムハースト |
サーモトロピック液晶セグメント化ブロックコポリマー
|
|
JPH08509612A
(ja)
|
1993-04-26 |
1996-10-15 |
ジェンファーム インターナショナル インコーポレイテッド |
異種抗体を産生することができるトランスジェニック非ヒト動物
|
|
AU760562B2
(en)
|
1997-12-05 |
2003-05-15 |
Scripps Research Institute, The |
Humanization of murine antibody
|
|
IL147765A0
(en)
|
1999-07-29 |
2002-08-14 |
Medarex Inc |
HUMAN MONOCLONAL ANTIBODIES TO HER2/neu
|
|
US7271240B2
(en)
|
2001-03-14 |
2007-09-18 |
Agensys, Inc. |
125P5C8: a tissue specific protein highly expressed in various cancers
|
|
US20040081653A1
(en)
|
2002-08-16 |
2004-04-29 |
Raitano Arthur B. |
Nucleic acids and corresponding proteins entitled 251P5G2 useful in treatment and detection of cancer
|
|
RU2386638C2
(ru)
|
2004-03-31 |
2010-04-20 |
Дженентек, Инк. |
Гуманизированные анти-тфр-бета-антитела
|
|
AR066476A1
(es)
|
2007-05-08 |
2009-08-19 |
Genentech Inc |
Anticuerpos anti-muc16 disenados con cisteina y conjugaods de anticuerpos y farmacos
|
|
CA2698541C
(en)
|
2007-10-19 |
2018-01-09 |
Genentech, Inc. |
Cysteine engineered anti-tenb2 antibodies and antibody drug conjugates
|
|
MX336540B
(es)
|
2010-06-08 |
2016-01-22 |
Genentech Inc |
Conjugados y anticuerpos manipulados geneticamente con cisteina.
|
|
MX347954B
(es)
|
2010-09-29 |
2017-05-19 |
Agensys Inc |
Conjugados de anticuerpo farmaco (adc) que enlazan a proteinas 191p4d12.
|
|
CN102469482A
(zh)
|
2010-11-12 |
2012-05-23 |
中兴通讯股份有限公司 |
一种广播控制信道信息倒换方法及系统
|
|
EP2729898A1
(en)
|
2011-07-10 |
2014-05-14 |
Blendology Limited |
An electronic data sharing device and method of use
|
|
US20140283153A1
(en)
|
2011-10-28 |
2014-09-18 |
Trianni, Inc. |
Transgenic animals and methods of use
|
|
EP2793947B1
(en)
|
2011-12-23 |
2021-02-03 |
Innate Pharma |
Enzymatic conjugation of polypeptides
|
|
HK1208216A1
(en)
|
2012-05-15 |
2016-02-26 |
Concortis Biosystems, Corp |
Drug-conjugates, conjugation methods, and uses thereof
|
|
ES2718478T3
(es)
|
2012-06-08 |
2019-07-02 |
Sutro Biopharma Inc |
Anticuerpos que comprenden restos de aminoácidos no naturales de localización específica, métodos para su preparación y métodos para su uso
|
|
NO2789793T3
(enExample)
|
2012-10-24 |
2018-01-27 |
|
|
|
US10036010B2
(en)
|
2012-11-09 |
2018-07-31 |
Innate Pharma |
Recognition tags for TGase-mediated conjugation
|
|
EP3010547B1
(en)
|
2013-06-20 |
2021-04-21 |
Innate Pharma |
Enzymatic conjugation of polypeptides
|
|
CN105517577A
(zh)
|
2013-06-21 |
2016-04-20 |
先天制药公司 |
多肽的酶促偶联
|
|
EP2845550B1
(de)
|
2013-09-10 |
2017-03-29 |
Erbe Elektromedizin GmbH |
Chirurgisches Instrument mit Kunststoffschaft
|
|
WO2015191883A1
(en)
|
2014-06-12 |
2015-12-17 |
Dophen Biomedical |
Homogenous antibody drug conjugates via enzymatic methods
|
|
SI3185908T1
(sl)
|
2014-08-28 |
2020-08-31 |
Pfizer Inc. |
Linkerji za modulacijo stabilnosti, ki se uporabljajo s konjugati zdravil s protitelesi
|
|
CN108289964B
(zh)
|
2015-08-10 |
2022-08-12 |
杭州多禧生物科技有限公司 |
新型连接体及其用于药物和生物分子的特异性偶联
|
|
US20180230238A1
(en)
|
2015-08-24 |
2018-08-16 |
Trianni, Inc |
Enhanced production of immunoglobulins
|
|
JP6985252B2
(ja)
*
|
2015-09-09 |
2021-12-22 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
ネクチン−4に対する特異性を有する抗体及びその使用
|
|
CN108472386A
(zh)
|
2015-10-02 |
2018-08-31 |
百时美施贵宝公司 |
用于缀合抗体的转谷氨酰胺酶变体
|
|
SG11201810591VA
(en)
*
|
2016-05-27 |
2018-12-28 |
Abbvie Biotherapeutics Inc |
Bispecific binding proteins binding an immunomodulatory protein and a tumor antigen
|
|
WO2018140590A1
(en)
|
2017-01-25 |
2018-08-02 |
Massachusetts Institute Of Technology |
Seft-labeling miniproteins and conjugates comprising them
|
|
WO2018158398A1
(en)
*
|
2017-03-02 |
2018-09-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies having specificity to nectin-4 and uses thereof
|
|
EP3606922A4
(en)
|
2017-04-06 |
2021-03-03 |
Hangzhou Dac Biotech Co., Ltd |
CONJUGATION OF A CYTOSTATIC WITH BIS CONNECTION
|
|
MX2019014318A
(es)
*
|
2017-06-05 |
2020-08-13 |
Agensys Inc |
Proteinas de union a nectina-4 y metodos de uso de las mismas.
|
|
JP6633247B1
(ja)
|
2018-05-07 |
2020-01-22 |
和寛 檜山 |
診断情報提供装置、方法及びシステム
|
|
CA3097679A1
(en)
|
2018-05-09 |
2019-11-14 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. |
Antibodies specific to human nectin4
|