JPWO2020076790A5 - - Google Patents

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Publication number
JPWO2020076790A5
JPWO2020076790A5 JP2021519609A JP2021519609A JPWO2020076790A5 JP WO2020076790 A5 JPWO2020076790 A5 JP WO2020076790A5 JP 2021519609 A JP2021519609 A JP 2021519609A JP 2021519609 A JP2021519609 A JP 2021519609A JP WO2020076790 A5 JPWO2020076790 A5 JP WO2020076790A5
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JP
Japan
Prior art keywords
antigen
antibody
binding fragment
seq
nos
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JP2021519609A
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English (en)
Japanese (ja)
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JP7459075B2 (ja
JP2022512646A (ja
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Priority claimed from PCT/US2019/055144 external-priority patent/WO2020076790A1/en
Publication of JP2022512646A publication Critical patent/JP2022512646A/ja
Publication of JPWO2020076790A5 publication Critical patent/JPWO2020076790A5/ja
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Publication of JP7459075B2 publication Critical patent/JP7459075B2/ja
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JP2021519609A 2018-10-09 2019-10-08 スタフィロコッカス・アウレウス(Staphylococcus aureus)ロイコトキシンに対して向けられた抗体 Active JP7459075B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862743501P 2018-10-09 2018-10-09
US62/743,501 2018-10-09
PCT/US2019/055144 WO2020076790A1 (en) 2018-10-09 2019-10-08 Antibodies directed against staphylococcus aureus leukotoxins

Publications (3)

Publication Number Publication Date
JP2022512646A JP2022512646A (ja) 2022-02-07
JPWO2020076790A5 true JPWO2020076790A5 (enExample) 2022-10-18
JP7459075B2 JP7459075B2 (ja) 2024-04-01

Family

ID=68393067

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021519609A Active JP7459075B2 (ja) 2018-10-09 2019-10-08 スタフィロコッカス・アウレウス(Staphylococcus aureus)ロイコトキシンに対して向けられた抗体

Country Status (11)

Country Link
US (2) US11059884B2 (enExample)
EP (1) EP3864040A1 (enExample)
JP (1) JP7459075B2 (enExample)
KR (1) KR20210080411A (enExample)
CN (1) CN113015745B (enExample)
AU (1) AU2019359207A1 (enExample)
BR (1) BR112021006704A2 (enExample)
CA (1) CA3115765A1 (enExample)
MX (1) MX2021004114A (enExample)
TW (1) TWI895248B (enExample)
WO (1) WO2020076790A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2917360T3 (da) * 2012-11-06 2020-03-30 Medimmune Llc Antistoffer mod S. aureus-overflade-determinanter
CA3107463A1 (en) 2018-07-24 2020-01-30 Medimmune, Llc Antibody directed against s. aureus clumping factor a (clfa)
JP7459075B2 (ja) 2018-10-09 2024-04-01 メディミューン,エルエルシー スタフィロコッカス・アウレウス(Staphylococcus aureus)ロイコトキシンに対して向けられた抗体
CN113164602A (zh) 2018-10-09 2021-07-23 免疫医疗有限责任公司 抗金黄色葡萄球菌抗体的组合
CN113811544A (zh) 2019-03-13 2021-12-17 免疫医疗有限责任公司 减少定殖患者中的金黄色葡萄球菌感染
CN113583119B (zh) * 2021-07-07 2023-05-02 西北农林科技大学 抗金黄色葡萄球菌的纳米抗体Nb56、应用及试剂盒
CN113493510A (zh) * 2021-07-07 2021-10-12 上海交通大学 一种牛源抗金黄色葡萄球菌LukD毒力因子的单链抗体及其制备和应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7658921B2 (en) 2000-12-12 2010-02-09 Medimmune, Llc Molecules with extended half-lives, compositions and uses thereof
US6881557B2 (en) 2001-07-12 2005-04-19 Arrowsmith Technologies Llp Super humanized antibodies
US20040014194A1 (en) 2002-03-27 2004-01-22 Schering Corporation Beta-secretase crystals and methods for preparing and using the same
JP5675109B2 (ja) 2007-02-20 2015-02-25 アナプティスバイオ インコーポレイティッド ライブラリーの生成方法及びその使用
EP2391384A4 (en) 2009-01-29 2012-12-26 Medimmune Llc HUMAN ANTI-IL-6 ANTIBODIES WITH EXTENDED IN VIVO HALF-TIME AND USE THEREOF FOR TREATMENTS IN ONCOLOGY AND FOR AUTOIMMUNE AND IGNITION
BR112012029521A2 (pt) * 2010-05-05 2018-03-06 New York University leucocidinas do staphylococcus aureus, composições terapêuticas, e aplicações das mesmas.
MX375113B (es) 2011-02-08 2025-03-04 Medimmune Llc Anticuerpos que se unen específicamente a la toxina alfa de staphylococcus aureus y métodos de uso.
DK2917360T3 (da) 2012-11-06 2020-03-30 Medimmune Llc Antistoffer mod S. aureus-overflade-determinanter
CN112316135A (zh) 2012-11-06 2021-02-05 米迪缪尼有限公司 治疗金黄色葡萄球菌相关疾病的方法
BR112016008275A2 (pt) * 2013-10-17 2017-10-03 Arsanis Biosciences Gmbh Anticorpo com reatividade cruzada ao staphylococcus aureus, preparações farmacêuticas ou para diagnóstico compreendendo o anticorpo, anticorpo para uso médico e para diagnóstico, um ácido nucleico isolado que codifica o anticorpo, plasmideo ou cassete de expressao, e célula hospedeira compreendendo tal plasmideo ou cassete de expressao, método para produzir o anticorpo usando tal célula hospedeira, método para produzir variantes de anticorpos, um cristal formado por um monômero da hla ou lukd com dito anticorpo, um paratopo isolado do anticorpo, o epítopo isolado e uma molécula de ligação ligando especificamente ao dito epítopo, um método de triagem para identificar um ligante que se liga ao dito epítopo, um imunógeno compreendendo dito epítopo, e dito imunógeno usado para induzir uma resposta imune protetora
ES2869459T3 (es) 2014-05-16 2021-10-25 Medimmune Llc Moléculas con unión a receptor de fc de neonato alterada que tiene propiedades terapéuticas y de diagnóstico potenciadas
TWI719938B (zh) 2014-06-19 2021-03-01 美商麥迪紐有限責任公司 多重細菌感染之治療
KR20170136637A (ko) 2015-04-17 2017-12-11 알사니스 바이오사이언시스 게엠베하 항-스타필로코커스 아우레우스 항체 배합 제제
US20190077851A1 (en) 2015-10-30 2019-03-14 Bruno Francois Methods of using anti-alpha toxin antibody
CA3107463A1 (en) 2018-07-24 2020-01-30 Medimmune, Llc Antibody directed against s. aureus clumping factor a (clfa)
JP7459075B2 (ja) 2018-10-09 2024-04-01 メディミューン,エルエルシー スタフィロコッカス・アウレウス(Staphylococcus aureus)ロイコトキシンに対して向けられた抗体
CN113164602A (zh) 2018-10-09 2021-07-23 免疫医疗有限责任公司 抗金黄色葡萄球菌抗体的组合

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