JPWO2021148610A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2021148610A5 JPWO2021148610A5 JP2022540698A JP2022540698A JPWO2021148610A5 JP WO2021148610 A5 JPWO2021148610 A5 JP WO2021148610A5 JP 2022540698 A JP2022540698 A JP 2022540698A JP 2022540698 A JP2022540698 A JP 2022540698A JP WO2021148610 A5 JPWO2021148610 A5 JP WO2021148610A5
- Authority
- JP
- Japan
- Prior art keywords
- lacto
- lnfp
- fucopentaose
- nucleic acid
- genetically modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA202000088 | 2020-01-23 | ||
| DKPA202000088 | 2020-01-23 | ||
| PCT/EP2021/051466 WO2021148610A1 (en) | 2020-01-23 | 2021-01-22 | Hmo production |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023511524A JP2023511524A (ja) | 2023-03-20 |
| JP2023511524A5 JP2023511524A5 (https=) | 2023-09-22 |
| JPWO2021148610A5 true JPWO2021148610A5 (https=) | 2023-09-22 |
Family
ID=74505190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022540698A Pending JP2023511524A (ja) | 2020-01-23 | 2021-01-22 | Ｈｍｏ産生 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230109661A1 (https=) |
| EP (1) | EP4093748A1 (https=) |
| JP (1) | JP2023511524A (https=) |
| CN (1) | CN114981291B (https=) |
| BR (1) | BR112022014420A2 (https=) |
| WO (1) | WO2021148610A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK181497B1 (en) | 2021-05-17 | 2024-03-12 | Dsm Ip Assets Bv | ENHANCING FORMATION OF THE HMOS LNT AND/OR LNnT BY MODIFYING LACTOSE IMPORT IN THE CELL |
| DK181991B1 (en) | 2021-11-11 | 2025-05-15 | Dsm Ip Assets Bv | Combined fermentation process for producing one or more human milk oligosaccharide(s) (hmo(s)) in escherichia coli |
| US20260028634A1 (en) | 2022-03-02 | 2026-01-29 | Dsm Ip Assets B.V. | New sialyltransferases for in vivo synthesis of 3'sl and 6'sl |
| DK181319B1 (en) | 2022-03-02 | 2023-08-10 | Dsm Ip Assets Bv | Genetically engineered cells and methods comprising use of a sialyltransferase for in vivo synthesis of 3’sl |
| DK181683B1 (en) | 2022-03-02 | 2024-09-20 | Dsm Ip Assets Bv | Cells exprssing new sialyltransferases for in vivo synthesis of lst-a, methods using same and constructs encoding said sialyltransferases |
| US20250290078A1 (en) | 2022-04-29 | 2025-09-18 | Dsm Ip Assets B.V. | Hmo producing microorganism with increased robustness towards glucose gradients |
| EP4577061A1 (en) | 2022-08-25 | 2025-07-02 | DSM IP Assets B.V. | Hybrid method for producing complex hmos |
| WO2024110667A1 (en) | 2022-11-25 | 2024-05-30 | Dsm Ip Assets B.V. | Two-strain system for producing oligosaccharides |
| CN120677242A (zh) | 2023-02-24 | 2025-09-19 | 帝斯曼知识产权资产管理有限公司 | 用于体内合成人乳寡糖的产物特异性转运蛋白 |
| DK181822B1 (en) | 2023-06-07 | 2025-01-30 | Dsm Ip Assets Bv | Genetically engineered strains with reduced byproduct formation and methods and uses of same |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2440661T3 (en) * | 2009-06-08 | 2018-03-12 | Jennewein Biotechnologie Gmbh | HMO synthesis |
| EP2675899A4 (en) | 2011-02-16 | 2014-09-10 | Glycosyn LLC | BIOSYNTHESIS OF HUMAN MILK OLIGOSACCHARIDES IN MANIPULATED BACTERIA |
| EP3461890B1 (en) * | 2014-03-31 | 2025-09-24 | Chr. Hansen HMO GmbH | Total fermentation of oligosaccharides |
| DE202015009782U1 (de) | 2014-06-11 | 2020-02-10 | Glycom A/S | Trennung von 2'-O-Fucosyllactose aus Fermentationsbrühe |
| EP3191499A4 (en) | 2014-09-09 | 2018-06-06 | Glycosyn LLC | Alpha (1,3) fucosyltransferases for use in the production of fucosylated oligosaccharides |
| US10676770B2 (en) | 2014-12-16 | 2020-06-09 | Glycom A/S | Separation of 2′-FL from a fermentation broth |
| EP3141610A1 (en) | 2015-09-12 | 2017-03-15 | Jennewein Biotechnologie GmbH | Production of human milk oligosaccharides in microbial hosts with engineered import / export |
| DE202017007249U1 (de) | 2016-03-07 | 2020-04-23 | Glycom A/S | Abtrennung von Oligosacchariden aus der Fermentationsbrühe |
| EP4674526A3 (en) | 2016-04-19 | 2026-04-01 | Glycom A/S | Separation of oligosaccharides from fermentation broth |
| ES2856749T3 (es) | 2016-10-29 | 2021-09-28 | Chr Hansen Hmo Gmbh | Proceso para la producción de oligosacáridos fucosilados |
| US11608504B2 (en) * | 2017-12-21 | 2023-03-21 | Glycom A/S | Nucleic acid construct for in vitro and in vivo gene expression |
| US20190323053A1 (en) | 2018-04-23 | 2019-10-24 | Dupont Nutrition Biosciences Aps | Increasing activity of 2? fucosyllactose transporters endogenous to microbial cells |
| US20190323052A1 (en) | 2018-04-23 | 2019-10-24 | Dupont Nutrition Biosciences Aps | Increasing export of 2? fucosyllactose from microbial cells through the expression of a heterologous nucleic acid |
| EP3569713A1 (en) * | 2018-05-16 | 2019-11-20 | Jennewein Biotechnologie GmbH | Use of glycosidases in the production of oligosaccharides |
| US10519475B1 (en) | 2018-11-21 | 2019-12-31 | Amyris, Inc. | Biosynthesis of compounds in yeast |
-
2021
- 2021-01-22 JP JP2022540698A patent/JP2023511524A/ja active Pending
- 2021-01-22 EP EP21702884.4A patent/EP4093748A1/en active Pending
- 2021-01-22 BR BR112022014420A patent/BR112022014420A2/pt not_active Application Discontinuation
- 2021-01-22 WO PCT/EP2021/051466 patent/WO2021148610A1/en not_active Ceased
- 2021-01-22 CN CN202180010202.2A patent/CN114981291B/zh active Active
- 2021-01-22 US US17/759,275 patent/US20230109661A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2021148615A5 (https=) | ||
| JPWO2021148611A5 (https=) | ||
| AU2024278250A1 (en) | Compositions and methods of treating Huntington's Disease | |
| CN115003687B (zh) | Hmo生产 | |
| JPWO2021148614A5 (https=) | ||
| CN114981291B (zh) | Hmo产生 | |
| CN115003814A (zh) | Hmo产生 | |
| JPWO2021148610A5 (https=) | ||
| CN114174520A (zh) | 用于选择性基因调节的组合物和方法 | |
| TW202208630A (zh) | 針對肌肉營養不良症的腺相關病毒載體遞送 | |
| US11446375B2 (en) | Endothelium-specific nucleic acid regulatory elements and methods and use thereof | |
| DK202001450A1 (en) | A dfl-producing strain | |
| KR20250102136A (ko) | 중추 신경계에서의 유전자 발현을 위한 핵산 조절 요소 및 사용 방법 | |
| CN118440186A (zh) | 一种广谱抗SARS-like冠状病毒和/或新冠突变株的抗体及其应用 | |
| CN110256539B (zh) | O型口蹄疫病毒新型基因工程亚单位疫苗 | |
| CN106350541A (zh) | 先天性免疫缺陷基因治疗载体构建方法及其用途 | |
| CN109280700A (zh) | 精确测定中华绒螯蟹线粒体全基因组序列的方法 | |
| CN103626851A (zh) | 一种镉离子结合多肽及其编码序列 | |
| CN115605266A (zh) | Dysferlin双载体的基因疗法 | |
| WO2007018318A1 (ja) | 小脳星状細胞及び／又は籠細胞特異的な遺伝子発現方法 | |
| CN104711240B (zh) | 禽呼肠孤病毒σA蛋白及其相关生物材料的应用 | |
| EP4007609A1 (en) | Targeted gene therapy to treat neurological diseases | |
| WO2022136388A1 (en) | Cardiomyocyte-derived nucleic acid regulatory elements and methods and use thereof | |
| CN118440187A (zh) | 一种抗SARS-like冠状病毒和/或新冠突变株的广谱抗体及其应用 | |
| CN106554968A (zh) | 日本血吸虫重组蛋白及其制备方法和应用 |