JPWO2020264253A5 - - Google Patents

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JPWO2020264253A5
JPWO2020264253A5 JP2021576250A JP2021576250A JPWO2020264253A5 JP WO2020264253 A5 JPWO2020264253 A5 JP WO2020264253A5 JP 2021576250 A JP2021576250 A JP 2021576250A JP 2021576250 A JP2021576250 A JP 2021576250A JP WO2020264253 A5 JPWO2020264253 A5 JP WO2020264253A5
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host cells
sois
cell
library
sequence
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JP2021576250A
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Japanese (ja)
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JP2022538073A (ja
JP7720787B2 (ja
JP2022538073A5 (https=
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Priority claimed from PCT/US2020/039753 external-priority patent/WO2020264253A1/en
Publication of JP2022538073A publication Critical patent/JP2022538073A/ja
Publication of JPWO2020264253A5 publication Critical patent/JPWO2020264253A5/ja
Publication of JP2022538073A5 publication Critical patent/JP2022538073A5/ja
Priority to JP2025073331A priority Critical patent/JP2025121945A/ja
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Publication of JP7720787B2 publication Critical patent/JP7720787B2/ja
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JP2021576250A 2019-06-26 2020-06-26 核酸のランダム化された構成標的化組込み Active JP7720787B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025073331A JP2025121945A (ja) 2019-06-26 2025-04-25 核酸のランダム化された構成標的化組込み

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962866893P 2019-06-26 2019-06-26
US62/866,893 2019-06-26
US202062991708P 2020-03-19 2020-03-19
US62/991,708 2020-03-19
PCT/US2020/039753 WO2020264253A1 (en) 2019-06-26 2020-06-26 Randomized configuration targeted integration of nucleic acids

Related Child Applications (1)

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JP2025073331A Division JP2025121945A (ja) 2019-06-26 2025-04-25 核酸のランダム化された構成標的化組込み

Publications (4)

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JP2022538073A JP2022538073A (ja) 2022-08-31
JPWO2020264253A5 true JPWO2020264253A5 (https=) 2023-07-04
JP2022538073A5 JP2022538073A5 (https=) 2023-07-04
JP7720787B2 JP7720787B2 (ja) 2025-08-08

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ID=71728890

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JP2021576250A Active JP7720787B2 (ja) 2019-06-26 2020-06-26 核酸のランダム化された構成標的化組込み
JP2025073331A Pending JP2025121945A (ja) 2019-06-26 2025-04-25 核酸のランダム化された構成標的化組込み

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JP2025073331A Pending JP2025121945A (ja) 2019-06-26 2025-04-25 核酸のランダム化された構成標的化組込み

Country Status (11)

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US (2) US11634836B2 (https=)
EP (1) EP3990649A1 (https=)
JP (2) JP7720787B2 (https=)
KR (1) KR20220025806A (https=)
CN (1) CN114080454A (https=)
AU (1) AU2020308002A1 (https=)
CA (1) CA3141233A1 (https=)
IL (1) IL289146A (https=)
MX (1) MX2021015698A (https=)
TW (1) TWI891643B (https=)
WO (1) WO2020264253A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021262798A1 (en) * 2020-06-24 2021-12-30 Genentech, Inc. Targeted integration of nucleic acids
CN117305334B (zh) * 2022-06-21 2024-11-08 深圳太力生物技术有限责任公司 靶向整合细胞及其制备方法、生产目标基因表达产物的方法
JP2026502534A (ja) * 2023-01-12 2026-01-23 ジェネンテック， インコーポレイテッド 核酸の標的組込みのためのコンビナトリアルベクターのクローニングおよびトランスフェクション戦略
CN116466074B (zh) * 2023-03-20 2026-02-24 吉林大学 基于特异性抗原fhh的肝片吸虫胶体金检测方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2096222C (en) 1990-11-13 1998-12-29 Stephen D. Lupton Bifunctional selectable fusion genes
WO1994028143A1 (en) 1993-05-21 1994-12-08 Targeted Genetics Corporation Bifunctional selectable fusion genes based on the cytosine deaminase (cd) gene
US7126041B1 (en) * 1999-12-10 2006-10-24 North Carolina State Unversity High efficiency gene targeting in plants
WO2008106985A1 (en) * 2007-03-07 2008-09-12 Aarhus Universitet Pig model
FR2927089B1 (fr) * 2008-02-05 2011-03-25 Inst Nat De La Rech Agronomique Inra Procede d'integration ciblee de multicopies d'un gene d'interet dans une souche de yarrowia
WO2014085711A1 (en) 2012-11-30 2014-06-05 Larix Biosciences Llc A novel cell line screening method
BR112015031639A2 (pt) * 2013-06-19 2019-09-03 Sigma Aldrich Co Llc integração alvo
US9932607B2 (en) * 2013-11-15 2018-04-03 The Board Of Trustees Of The Leland Stanford Junior University Site-specific integration of transgenes into human cells
GB201407852D0 (en) 2014-05-02 2014-06-18 Iontas Ltd Preparation of libraries od protein variants expressed in eukaryotic cells and use for selecting binding molecules
KR102243243B1 (ko) 2014-10-23 2021-04-22 리제너론 파마슈티칼스 인코포레이티드 신규한 cho 통합 부위 및 이의 용도
EA201892137A1 (ru) 2016-04-20 2019-03-29 Регенерон Фармасьютикалз, Инк. Композиции и способы получения антител, основанные на применении локусов, обеспечивающих повышенную экспрессию
US11512144B2 (en) 2016-04-20 2022-11-29 Regeneran Pharmaceuticals, Inc. Compositions and methods for making antibodies based on use of an expression-enhancing loci
IL275462B2 (en) * 2017-12-22 2026-01-01 Genentech Inc Targeted integration of nucleic acids
AU2019403279A1 (en) * 2018-12-21 2021-07-01 Genentech, Inc. Targeted integration of nucleic acids

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