JP2022538073A5 - - Google Patents
Info
- Publication number
- JP2022538073A5 JP2022538073A5 JP2021576250A JP2021576250A JP2022538073A5 JP 2022538073 A5 JP2022538073 A5 JP 2022538073A5 JP 2021576250 A JP2021576250 A JP 2021576250A JP 2021576250 A JP2021576250 A JP 2021576250A JP 2022538073 A5 JP2022538073 A5 JP 2022538073A5
- Authority
- JP
- Japan
- Prior art keywords
- host cells
- sois
- cell
- library
- specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025073331A JP2025121945A (ja) | 2019-06-26 | 2025-04-25 | 核酸のランダム化された構成標的化組込み |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962866893P | 2019-06-26 | 2019-06-26 | |
| US62/866,893 | 2019-06-26 | ||
| US202062991708P | 2020-03-19 | 2020-03-19 | |
| US62/991,708 | 2020-03-19 | ||
| PCT/US2020/039753 WO2020264253A1 (en) | 2019-06-26 | 2020-06-26 | Randomized configuration targeted integration of nucleic acids |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025073331A Division JP2025121945A (ja) | 2019-06-26 | 2025-04-25 | 核酸のランダム化された構成標的化組込み |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022538073A JP2022538073A (ja) | 2022-08-31 |
| JP2022538073A5 true JP2022538073A5 (https=) | 2023-07-04 |
| JP7720787B2 JP7720787B2 (ja) | 2025-08-08 |
Family
ID=71728890
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021576250A Active JP7720787B2 (ja) | 2019-06-26 | 2020-06-26 | 核酸のランダム化された構成標的化組込み |
| JP2025073331A Pending JP2025121945A (ja) | 2019-06-26 | 2025-04-25 | 核酸のランダム化された構成標的化組込み |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025073331A Pending JP2025121945A (ja) | 2019-06-26 | 2025-04-25 | 核酸のランダム化された構成標的化組込み |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11634836B2 (https=) |
| EP (1) | EP3990649A1 (https=) |
| JP (2) | JP7720787B2 (https=) |
| KR (1) | KR20220025806A (https=) |
| CN (1) | CN114080454A (https=) |
| AU (1) | AU2020308002A1 (https=) |
| CA (1) | CA3141233A1 (https=) |
| IL (1) | IL289146A (https=) |
| MX (1) | MX2021015698A (https=) |
| TW (1) | TWI891643B (https=) |
| WO (1) | WO2020264253A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023532665A (ja) * | 2020-06-24 | 2023-07-31 | ジェネンテック， インコーポレイテッド | 核酸の標的化組み込み |
| CN117305334B (zh) * | 2022-06-21 | 2024-11-08 | 深圳太力生物技术有限责任公司 | 靶向整合细胞及其制备方法、生产目标基因表达产物的方法 |
| EP4649148A1 (en) * | 2023-01-12 | 2025-11-19 | Genentech, Inc. | Combinatorial vector cloning and transfection strategies for targeted integration of nucleic acids |
| CN116466074B (zh) * | 2023-03-20 | 2026-02-24 | 吉林大学 | 基于特异性抗原fhh的肝片吸虫胶体金检测方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE913929A1 (en) | 1990-11-13 | 1992-05-20 | Immunex Corp | Bifunctional selectable fusion genes |
| AU6953394A (en) | 1993-05-21 | 1994-12-20 | Targeted Genetics Corporation | Bifunctional selectable fusion genes based on the cytosine deaminase (cd) gene |
| US7126041B1 (en) * | 1999-12-10 | 2006-10-24 | North Carolina State Unversity | High efficiency gene targeting in plants |
| WO2008106985A1 (en) * | 2007-03-07 | 2008-09-12 | Aarhus Universitet | Pig model |
| FR2927089B1 (fr) * | 2008-02-05 | 2011-03-25 | Inst Nat De La Rech Agronomique Inra | Procede d'integration ciblee de multicopies d'un gene d'interet dans une souche de yarrowia |
| EP2925867B1 (en) | 2012-11-30 | 2018-06-27 | Larix Biosciences LLC | A novel cell line screening method |
| BR112015031639A2 (pt) | 2013-06-19 | 2019-09-03 | Sigma Aldrich Co Llc | integração alvo |
| US9932607B2 (en) * | 2013-11-15 | 2018-04-03 | The Board Of Trustees Of The Leland Stanford Junior University | Site-specific integration of transgenes into human cells |
| GB201407852D0 (en) | 2014-05-02 | 2014-06-18 | Iontas Ltd | Preparation of libraries od protein variants expressed in eukaryotic cells and use for selecting binding molecules |
| BR112017008022A2 (pt) | 2014-10-23 | 2018-02-20 | Regeneron Pharmaceuticals, Inc. | célula, polinucleotídeo, veículo, e, métodos para modificação de um genoma de células cho e para preparação de uma proteína de interesse. |
| BR112018071285A2 (pt) | 2016-04-20 | 2019-02-12 | Regeneron Pharma | célula, conjunto de vetores, vetor, sistema, e, método |
| SG11201807885PA (en) * | 2016-04-20 | 2018-10-30 | Regeneron Pharma | Compositions and methods for making antibodies based on use of expression-enhancing loci |
| IL275462B2 (en) * | 2017-12-22 | 2026-01-01 | Genentech Inc | Targeted integration of nucleic acids |
| AU2019403279A1 (en) * | 2018-12-21 | 2021-07-01 | Genentech, Inc. | Targeted integration of nucleic acids |
-
2020
- 2020-06-26 AU AU2020308002A patent/AU2020308002A1/en not_active Abandoned
- 2020-06-26 EP EP20743418.4A patent/EP3990649A1/en active Pending
- 2020-06-26 JP JP2021576250A patent/JP7720787B2/ja active Active
- 2020-06-26 KR KR1020227000914A patent/KR20220025806A/ko active Pending
- 2020-06-26 WO PCT/US2020/039753 patent/WO2020264253A1/en not_active Ceased
- 2020-06-26 CA CA3141233A patent/CA3141233A1/en active Pending
- 2020-06-26 CN CN202080047399.2A patent/CN114080454A/zh active Pending
- 2020-06-26 MX MX2021015698A patent/MX2021015698A/es unknown
- 2020-06-29 TW TW109121966A patent/TWI891643B/zh active
-
2021
- 2021-12-19 IL IL289146A patent/IL289146A/en unknown
- 2021-12-27 US US17/562,950 patent/US11634836B2/en active Active
-
2023
- 2023-04-03 US US18/129,976 patent/US20230279583A1/en active Pending
-
2025
- 2025-04-25 JP JP2025073331A patent/JP2025121945A/ja active Pending
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