JPWO2020225934A5 - - Google Patents
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- Publication number
- JPWO2020225934A5 JPWO2020225934A5 JP2021518296A JP2021518296A JPWO2020225934A5 JP WO2020225934 A5 JPWO2020225934 A5 JP WO2020225934A5 JP 2021518296 A JP2021518296 A JP 2021518296A JP 2021518296 A JP2021518296 A JP 2021518296A JP WO2020225934 A5 JPWO2020225934 A5 JP WO2020225934A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- hair follicle
- epithelial cells
- culture medium
- mesenchymal cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000003780 hair follicle Anatomy 0.000 claims 14
- 210000002919 epithelial cell Anatomy 0.000 claims 13
- 210000004027 cell Anatomy 0.000 claims 9
- 239000001963 growth medium Substances 0.000 claims 8
- 238000004519 manufacturing process Methods 0.000 claims 6
- 210000002782 epithelial mesenchymal cell Anatomy 0.000 claims 5
- 102000004266 Collagen Type IV Human genes 0.000 claims 4
- 108010042086 Collagen Type IV Proteins 0.000 claims 4
- 102100037369 Nidogen-1 Human genes 0.000 claims 4
- 238000012258 culturing Methods 0.000 claims 4
- 210000004209 hair Anatomy 0.000 claims 4
- 108010008217 nidogen Proteins 0.000 claims 4
- 239000012530 fluid Substances 0.000 claims 3
- 238000010899 nucleation Methods 0.000 claims 3
- 230000000717 retained effect Effects 0.000 claims 3
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 238000004113 cell culture Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 238000003501 co-culture Methods 0.000 claims 1
- 230000014759 maintenance of location Effects 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 210000001732 sebaceous gland Anatomy 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019087747 | 2019-05-07 | ||
| JP2019087747 | 2019-05-07 | ||
| PCT/JP2019/031142 WO2020225934A1 (ja) | 2019-05-07 | 2019-08-07 | 毛包原基及びその製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2020225934A1 JPWO2020225934A1 (https=) | 2020-11-12 |
| JPWO2020225934A5 true JPWO2020225934A5 (https=) | 2022-07-21 |
| JP7427180B2 JP7427180B2 (ja) | 2024-02-05 |
Family
ID=73050764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021518296A Active JP7427180B2 (ja) | 2019-05-07 | 2019-08-07 | 毛包原基及びその製造方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220228113A1 (https=) |
| EP (1) | EP3967749A4 (https=) |
| JP (1) | JP7427180B2 (https=) |
| CN (1) | CN113785047B (https=) |
| WO (1) | WO2020225934A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7847810B2 (ja) * | 2021-10-08 | 2026-04-20 | 国立大学法人横浜国立大学 | 毛髪再生能を有する細胞凝集塊の製造方法及びこれに関連する方法 |
| JP2023056592A (ja) * | 2021-10-08 | 2023-04-20 | 国立大学法人横浜国立大学 | 移植用毛様組織及びこれに関連する方法 |
| JP2025067221A (ja) * | 2023-10-12 | 2025-04-24 | 国立大学法人横浜国立大学 | 毛乳頭細胞活性化用組成物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0605450D0 (en) * | 2006-03-17 | 2006-04-26 | Intercytex Ltd | Cell co-culture |
| EP2105499A1 (en) * | 2008-03-28 | 2009-09-30 | Technische Universität Berlin | Methods for producing de novo papillae and hair microfollicles and their use for in vitro tests and in vivo implantations |
| EP2991692B1 (en) * | 2013-05-03 | 2019-08-21 | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | Skin substitutes and methods for hair follicle neogenesis |
| US20180355315A1 (en) | 2014-09-08 | 2018-12-13 | Organ Technologies, Inc. | Method of producing full thickness skin having skin accessory organs |
| EP3351621B1 (en) | 2015-10-30 | 2023-11-22 | National University Corporation Yokohama National University | Regenerated hair follicle primordium aggregation manufacturing method, hair follicle tissue-containing sheet, and method for manufacturing hair follicle tissue-containing sheet |
| JP6857877B2 (ja) * | 2016-11-21 | 2021-04-14 | 国立大学法人横浜国立大学 | 毛細血管構造を有する再生毛包原基の集合体の製造方法、毛包組織含有シート、及び毛包組織含有シートの製造方法 |
| US20200208106A1 (en) | 2017-08-22 | 2020-07-02 | National University Corporation Yokohama National University | Production Method of Multiple Regenerated Hair Follicle Primordia, Production Method of Hair Follicle Tissue-Containing Sheet, Hair Regeneration Kit and Method for Screening Hair Growth promoter or Hair Growth Inhibitor |
| CN109395165A (zh) * | 2018-12-21 | 2019-03-01 | 江阴司特易生物技术有限公司 | 一种人工复合神经导管及制备方法 |
-
2019
- 2019-08-07 WO PCT/JP2019/031142 patent/WO2020225934A1/ja not_active Ceased
- 2019-08-07 CN CN201980096118.XA patent/CN113785047B/zh active Active
- 2019-08-07 JP JP2021518296A patent/JP7427180B2/ja active Active
- 2019-08-07 EP EP19927959.7A patent/EP3967749A4/en active Pending
- 2019-08-07 US US17/609,164 patent/US20220228113A1/en active Pending