JP2020523013A5 - - Google Patents
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- JP2020523013A5 JP2020523013A5 JP2019567628A JP2019567628A JP2020523013A5 JP 2020523013 A5 JP2020523013 A5 JP 2020523013A5 JP 2019567628 A JP2019567628 A JP 2019567628A JP 2019567628 A JP2019567628 A JP 2019567628A JP 2020523013 A5 JP2020523013 A5 JP 2020523013A5
- Authority
- JP
- Japan
- Prior art keywords
- day
- beno
- matrix
- neural
- culturing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17175874 | 2017-06-13 | ||
| EP17175874.1 | 2017-06-13 | ||
| EP17205951.1 | 2017-12-07 | ||
| EP17205951.1A EP3415618B1 (en) | 2017-06-13 | 2017-12-07 | Methods of producing bioengineered neuronal organoids (benos) and uses thereof |
| PCT/EP2018/065204 WO2018228948A1 (en) | 2017-06-13 | 2018-06-08 | Methods of producing bioengineered neuronal organoids (benos) and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020523013A JP2020523013A (ja) | 2020-08-06 |
| JP2020523013A5 true JP2020523013A5 (https=) | 2021-08-05 |
| JP7340252B2 JP7340252B2 (ja) | 2023-09-07 |
Family
ID=59239778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019567628A Active JP7340252B2 (ja) | 2017-06-13 | 2018-06-08 | 生物工学的に作製された神経オルガノイド（ｂｅｎｏｓ）の生産方法およびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11781109B2 (https=) |
| EP (1) | EP3415618B1 (https=) |
| JP (1) | JP7340252B2 (https=) |
| KR (1) | KR102590084B1 (https=) |
| CN (1) | CN110741078B (https=) |
| AU (1) | AU2018283364B2 (https=) |
| CA (1) | CA3067068C (https=) |
| DK (1) | DK3415618T3 (https=) |
| ES (1) | ES2903187T3 (https=) |
| WO (1) | WO2018228948A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12599670B2 (en) | 2014-12-12 | 2026-04-14 | The Trustees Of The University Of Pennsylvania | Composition comprising three-dimensional astrocyte bundles of bi-polar and aligned astrocyte processes and a method of making thereof |
| WO2017181068A1 (en) | 2016-04-14 | 2017-10-19 | The Trustees Of The University Of Pennsylvania | Implantable living electrodes and methods for use thereof |
| CN108456659B (zh) | 2018-03-14 | 2020-05-05 | 浙江霍德生物工程有限公司 | 3d大脑类器官的制备方法 |
| WO2020165059A1 (en) * | 2019-02-11 | 2020-08-20 | Miltenyi Biotec B.V. & Co. KG | Generation of human pluripotent stem cell derived artificial tissue structures without three dimensional matrices |
| US20220233602A1 (en) * | 2019-07-05 | 2022-07-28 | Novo Nordisk A/S | Generation of neural stem cell lines derived from human pluripotent stem cells |
| CN112481212A (zh) * | 2020-11-27 | 2021-03-12 | 杭州联众医疗科技股份有限公司 | 一种利用多能干细胞生成脑部类器官的方法 |
| KR102638839B1 (ko) * | 2021-04-06 | 2024-02-23 | 충북대학교 산학협력단 | 돼지 신경 오가노이드 제조방법 |
| WO2022256643A1 (en) * | 2021-06-04 | 2022-12-08 | The Trustees Of The University Of Pennsylvania | Tissue-engineered rostral migratory stream for neuronal replacement |
| CN115404218B (zh) * | 2022-01-13 | 2024-09-24 | 南华大学附属第一医院 | 一种包含胶质细胞的3d人脑类器官培养方法 |
| EP4386384A1 (en) | 2022-12-15 | 2024-06-19 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin | Potency assay for pharmaceutical products |
| CN116159182B (zh) * | 2023-02-02 | 2024-09-24 | 中国科学院苏州纳米技术与纳米仿生研究所 | 用于治疗脊髓损伤的神经类器官-水凝胶体系及制备方法 |
| CN118272307A (zh) * | 2024-04-23 | 2024-07-02 | 妙顺（上海）生物科技有限公司 | 一种神经类器官三维培养诱导分化的方法及其应用 |
| EP4678739A1 (en) * | 2024-07-10 | 2026-01-14 | Fundación Pública Andaluza Progreso Y Salud | In vitro method for obtaining cortical brain organoids, cortical brain organoids and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8343923B2 (en) * | 2007-11-09 | 2013-01-01 | Washington University | Use of notch signaling regulators for modulating osteogenesis |
| US10227563B2 (en) * | 2008-06-06 | 2019-03-12 | Riken | Method for culture of stem cell |
| JP6185907B2 (ja) * | 2011-03-30 | 2017-08-23 | セルラー ダイナミクス インターナショナル， インコーポレイテッド | 神経分化のための多能性幹細胞の予備刺激 |
| EP2743345A1 (en) * | 2012-12-13 | 2014-06-18 | IMBA-Institut für Molekulare Biotechnologie GmbH | Three dimensional heterogeneously differentiated tissue culture |
| JP2016521971A (ja) * | 2013-04-23 | 2016-07-28 | イェダ リサーチ アンド ディベロップメント カンパニー リミテッド | 単離ナイーブ型多能性幹細胞およびそれを発生させる方法関連出願本出願は、米国特許法１１９条第（ｅ）項に基づき、２０１４年１月２９日出願の米国特許仮出願第６１／９３２，９３５号、２０１３年９月１７日出願の米国特許仮出願第６１／８７８，７６９号、および２０１３年４月２３日出願の米国特許仮出願第６１／８１４，９２０号の優先権を主張する。また、本出願は、同時に提出された同出願人による同時係属出願である、ＹａｑｕｂＨＡＮＮＡ、ＮｏａＮＯＶＥＲＳＨＴＥＲＮ、およびＹｏａｃｈＲＡＩＳによる米国特許出願（発明の名称「単離ナイーブ型多能性幹細胞およびそれを発生させる方法（ＩＳＯＬＡＴＥＤＮＡＩＶＥＰＬＵＲＩＰＯＴＥＮＴＳＴＥＭＣＥＬＬＳＡＮＤＭＥＴＨＯＤＳＯＦＧＥＮＥＲＡＴＩＮＧＳＡＭＥ）」）（代理人事件記録簿第５８８７０号）にも関する。上記出願の内容はその全体を参考として本明細書に組み込む。 |
| AU2015261380B2 (en) * | 2014-05-16 | 2021-04-15 | Koninklijke Nederlandse Akademie Van Wetenschappen | Improved culture method for organoids |
| WO2016028880A1 (en) * | 2014-08-19 | 2016-02-25 | Cellular Dynamics International, Inc. | Neural networks formed from cells derived from pluripotent stem cells |
| LU92845B1 (en) * | 2015-10-08 | 2017-05-02 | Univ Du Luxembourg Campus Belval | Means and methods for generating midbrain organoids |
| WO2017117547A1 (en) * | 2015-12-31 | 2017-07-06 | President And Fellows Of Harvard College | Methods for generating neural tissue and uses thereof |
| EP3190176A1 (en) * | 2016-01-11 | 2017-07-12 | IMBA-Institut für Molekulare Biotechnologie GmbH | Method for tissue culture development on scaffold and differentiated tissue culture |
-
2017
- 2017-12-07 EP EP17205951.1A patent/EP3415618B1/en active Active
- 2017-12-07 DK DK17205951.1T patent/DK3415618T3/da active
- 2017-12-07 ES ES17205951T patent/ES2903187T3/es active Active
-
2018
- 2018-06-08 WO PCT/EP2018/065204 patent/WO2018228948A1/en not_active Ceased
- 2018-06-08 CA CA3067068A patent/CA3067068C/en active Active
- 2018-06-08 KR KR1020197037323A patent/KR102590084B1/ko active Active
- 2018-06-08 JP JP2019567628A patent/JP7340252B2/ja active Active
- 2018-06-08 CN CN201880038743.4A patent/CN110741078B/zh active Active
- 2018-06-08 US US16/621,707 patent/US11781109B2/en active Active
- 2018-06-08 AU AU2018283364A patent/AU2018283364B2/en active Active
-
2023
- 2023-08-21 US US18/453,306 patent/US20250067727A1/en active Pending
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