JP2020523013A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020523013A5 JP2020523013A5 JP2019567628A JP2019567628A JP2020523013A5 JP 2020523013 A5 JP2020523013 A5 JP 2020523013A5 JP 2019567628 A JP2019567628 A JP 2019567628A JP 2019567628 A JP2019567628 A JP 2019567628A JP 2020523013 A5 JP2020523013 A5 JP 2020523013A5
- Authority
- JP
- Japan
- Prior art keywords
- day
- beno
- matrix
- neural
- culturing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17175874 | 2017-06-13 | ||
| EP17175874.1 | 2017-06-13 | ||
| EP17205951.1A EP3415618B1 (en) | 2017-06-13 | 2017-12-07 | Methods of producing bioengineered neuronal organoids (benos) and uses thereof |
| EP17205951.1 | 2017-12-07 | ||
| PCT/EP2018/065204 WO2018228948A1 (en) | 2017-06-13 | 2018-06-08 | Methods of producing bioengineered neuronal organoids (benos) and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020523013A JP2020523013A (ja) | 2020-08-06 |
| JP2020523013A5 true JP2020523013A5 (https=) | 2021-08-05 |
| JP7340252B2 JP7340252B2 (ja) | 2023-09-07 |
Family
ID=59239778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019567628A Active JP7340252B2 (ja) | 2017-06-13 | 2018-06-08 | 生物工学的に作製された神経オルガノイド（ｂｅｎｏｓ）の生産方法およびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11781109B2 (https=) |
| EP (1) | EP3415618B1 (https=) |
| JP (1) | JP7340252B2 (https=) |
| KR (1) | KR102590084B1 (https=) |
| CN (1) | CN110741078B (https=) |
| AU (1) | AU2018283364B2 (https=) |
| CA (1) | CA3067068C (https=) |
| DK (1) | DK3415618T3 (https=) |
| ES (1) | ES2903187T3 (https=) |
| WO (1) | WO2018228948A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016094850A1 (en) | 2014-12-12 | 2016-06-16 | The Trustees Of The University Of Pennsylvania | Methods of Promoting Nervous System Regeneration |
| EP3442409A4 (en) | 2016-04-14 | 2019-11-13 | The Trustees of The University of Pennsylvania | IMPLANTABLE LIVING ELECTRODES AND METHOD FOR USE THEREOF |
| CN108456659B (zh) | 2018-03-14 | 2020-05-05 | 浙江霍德生物工程有限公司 | 3d大脑类器官的制备方法 |
| US20220145247A1 (en) * | 2019-02-11 | 2022-05-12 | Miltenyi Biotec B.V. & Co. KG | Generation of human pluripotent stem cell derived artificial tissue structures without three dimensional matrices |
| WO2021004864A1 (en) * | 2019-07-05 | 2021-01-14 | Novo Nordisk A/S | Generation of neural stem cell lines derived from human pluripotent stem cells |
| CN112481212A (zh) * | 2020-11-27 | 2021-03-12 | 杭州联众医疗科技股份有限公司 | 一种利用多能干细胞生成脑部类器官的方法 |
| KR102638839B1 (ko) * | 2021-04-06 | 2024-02-23 | 충북대학교 산학협력단 | 돼지 신경 오가노이드 제조방법 |
| WO2022256643A1 (en) * | 2021-06-04 | 2022-12-08 | The Trustees Of The University Of Pennsylvania | Tissue-engineered rostral migratory stream for neuronal replacement |
| CN115404218B (zh) * | 2022-01-13 | 2024-09-24 | 南华大学附属第一医院 | 一种包含胶质细胞的3d人脑类器官培养方法 |
| EP4386384A1 (en) | 2022-12-15 | 2024-06-19 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin | Potency assay for pharmaceutical products |
| CN116159182B (zh) * | 2023-02-02 | 2024-09-24 | 中国科学院苏州纳米技术与纳米仿生研究所 | 用于治疗脊髓损伤的神经类器官-水凝胶体系及制备方法 |
| CN118272307A (zh) * | 2024-04-23 | 2024-07-02 | 妙顺（上海）生物科技有限公司 | 一种神经类器官三维培养诱导分化的方法及其应用 |
| EP4678739A1 (en) * | 2024-07-10 | 2026-01-14 | Fundación Pública Andaluza Progreso Y Salud | In vitro method for obtaining cortical brain organoids, cortical brain organoids and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8343923B2 (en) * | 2007-11-09 | 2013-01-01 | Washington University | Use of notch signaling regulators for modulating osteogenesis |
| JPWO2009148170A1 (ja) * | 2008-06-06 | 2011-11-04 | 独立行政法人理化学研究所 | 幹細胞の培養方法 |
| DK2694644T3 (en) * | 2011-03-30 | 2018-04-16 | Cellular Dynamics Int Inc | Priming of pluripotent stem cells for neural differentiation |
| EP2743345A1 (en) | 2012-12-13 | 2014-06-18 | IMBA-Institut für Molekulare Biotechnologie GmbH | Three dimensional heterogeneously differentiated tissue culture |
| CN105531365A (zh) * | 2013-04-23 | 2016-04-27 | 耶达研究及发展有限公司 | 分离的幼稚多能干细胞和产生所述细胞的方法 |
| CA2949171A1 (en) * | 2014-05-16 | 2015-11-19 | Koninklijke Nederlandse Akademie Van Wetenschappen | Improved culture method for organoids |
| AU2015305515B2 (en) * | 2014-08-19 | 2020-12-03 | FUJIFILM Cellular Dynamics, Inc. | Neural networks formed from cells derived from pluripotent stem cells |
| LU92845B1 (en) * | 2015-10-08 | 2017-05-02 | Univ Du Luxembourg Campus Belval | Means and methods for generating midbrain organoids |
| WO2017117547A1 (en) * | 2015-12-31 | 2017-07-06 | President And Fellows Of Harvard College | Methods for generating neural tissue and uses thereof |
| EP3190176A1 (en) * | 2016-01-11 | 2017-07-12 | IMBA-Institut für Molekulare Biotechnologie GmbH | Method for tissue culture development on scaffold and differentiated tissue culture |
-
2017
- 2017-12-07 ES ES17205951T patent/ES2903187T3/es active Active
- 2017-12-07 EP EP17205951.1A patent/EP3415618B1/en active Active
- 2017-12-07 DK DK17205951.1T patent/DK3415618T3/da active
-
2018
- 2018-06-08 KR KR1020197037323A patent/KR102590084B1/ko active Active
- 2018-06-08 CN CN201880038743.4A patent/CN110741078B/zh active Active
- 2018-06-08 AU AU2018283364A patent/AU2018283364B2/en active Active
- 2018-06-08 JP JP2019567628A patent/JP7340252B2/ja active Active
- 2018-06-08 WO PCT/EP2018/065204 patent/WO2018228948A1/en not_active Ceased
- 2018-06-08 CA CA3067068A patent/CA3067068C/en active Active
- 2018-06-08 US US16/621,707 patent/US11781109B2/en active Active
-
2023
- 2023-08-21 US US18/453,306 patent/US20250067727A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020523013A5 (https=) | ||
| Tani et al. | Understanding paraxial mesoderm development and sclerotome specification for skeletal repair | |
| Vats et al. | Chondrogenic differentiation of human embryonic stem cells: the effect of the micro-environment | |
| DuRaine et al. | Emergence of scaffold-free approaches for tissue engineering musculoskeletal cartilages | |
| Franck et al. | Evaluation of silk biomaterials in combination with extracellular matrix coatings for bladder tissue engineering with primary and pluripotent cells | |
| Huber et al. | Phenotypic changes in cultured smooth muscle cells: limitation or opportunity for tissue engineering of hollow organs? | |
| JP2019141074A (ja) | 軟骨細胞系統細胞及び／又は軟骨様組織を作製するための方法及び組成物 | |
| Pagliarosi et al. | Building an artificial cardiac microenvironment: A focus on the extracellular matrix | |
| Hofbauer et al. | In vitro models of the human heart | |
| Shi et al. | Enhanced osteogenesis by a biomimic pseudo‐periosteum‐involved tissue engineering Strategy | |
| CN116249767A (zh) | 人多能干细胞来源的心脏类器官的制备方法以及由其制备而得的人多能干细胞来源的心脏类器官 | |
| Rodboon et al. | Development of high-throughput lacrimal gland organoid platforms for drug discovery in dry eye disease | |
| JP7376760B2 (ja) | 多能性幹細胞から各種細胞への段階的製造方法 | |
| Stephenson et al. | Induced pluripotent stem cell-derived vascular smooth muscle cells | |
| Hu et al. | Patient-specific cardiovascular progenitor cells derived from integration-free induced pluripotent stem cells for vascular tissue regeneration | |
| Little et al. | Generating a self-organizing kidney from pluripotent cells | |
| Zhao et al. | Organoid models for salivary gland biology and regenerative medicine | |
| Shankar et al. | From Snapshots to Development: Identifying the Gaps in the Development of Stem Cell‐based Embryo Models along the Embryonic Timeline | |
| Zhao et al. | Application of stem cells in engineered vascular graft and vascularized organs | |
| Ren et al. | The building blocks of embryo models: embryonic and extraembryonic stem cells | |
| Biswas et al. | Applications, challenges, and prospects of induced pluripotent stem cells for vascular disease | |
| CN116751738B (zh) | 一种信号巢细胞以及类胚胎的制备方法 | |
| Gerwinn et al. | Spheroids of bladder smooth muscle cells for bladder tissue engineering | |
| Mai et al. | Application of hiPSCs in tooth regeneration via cellular modulation | |
| Hwang et al. | Directing embryonic stem cell differentiation into osteogenic chondrogenic lineage in vitro |