CN110741078B - 用于产生生物工程化的神经元类器官(beno)的方法及其用途 - Google Patents

用于产生生物工程化的神经元类器官(beno)的方法及其用途 Download PDF

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CN110741078B
CN110741078B CN201880038743.4A CN201880038743A CN110741078B CN 110741078 B CN110741078 B CN 110741078B CN 201880038743 A CN201880038743 A CN 201880038743A CN 110741078 B CN110741078 B CN 110741078B
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beno
day
cells
neuronal
matrix
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CN110741078A (zh
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W-H·齐默尔曼
M·P·扎菲里奥
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Georg August Universitaet Goettingen
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CN201880038743.4A 2017-06-13 2018-06-08 用于产生生物工程化的神经元类器官(beno)的方法及其用途 Active CN110741078B (zh)

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Application Number Priority Date Filing Date Title
EP17175874 2017-06-13
EP17175874.1 2017-06-13
EP17205951.1 2017-12-07
EP17205951.1A EP3415618B1 (en) 2017-06-13 2017-12-07 Methods of producing bioengineered neuronal organoids (benos) and uses thereof
PCT/EP2018/065204 WO2018228948A1 (en) 2017-06-13 2018-06-08 Methods of producing bioengineered neuronal organoids (benos) and uses thereof

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CN110741078A CN110741078A (zh) 2020-01-31
CN110741078B true CN110741078B (zh) 2024-01-23

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US (2) US11781109B2 (https=)
EP (1) EP3415618B1 (https=)
JP (1) JP7340252B2 (https=)
KR (1) KR102590084B1 (https=)
CN (1) CN110741078B (https=)
AU (1) AU2018283364B2 (https=)
CA (1) CA3067068C (https=)
DK (1) DK3415618T3 (https=)
ES (1) ES2903187T3 (https=)
WO (1) WO2018228948A1 (https=)

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US12599670B2 (en) 2014-12-12 2026-04-14 The Trustees Of The University Of Pennsylvania Composition comprising three-dimensional astrocyte bundles of bi-polar and aligned astrocyte processes and a method of making thereof
WO2017181068A1 (en) 2016-04-14 2017-10-19 The Trustees Of The University Of Pennsylvania Implantable living electrodes and methods for use thereof
CN108456659B (zh) 2018-03-14 2020-05-05 浙江霍德生物工程有限公司 3d大脑类器官的制备方法
WO2020165059A1 (en) * 2019-02-11 2020-08-20 Miltenyi Biotec B.V. & Co. KG Generation of human pluripotent stem cell derived artificial tissue structures without three dimensional matrices
US20220233602A1 (en) * 2019-07-05 2022-07-28 Novo Nordisk A/S Generation of neural stem cell lines derived from human pluripotent stem cells
CN112481212A (zh) * 2020-11-27 2021-03-12 杭州联众医疗科技股份有限公司 一种利用多能干细胞生成脑部类器官的方法
KR102638839B1 (ko) * 2021-04-06 2024-02-23 충북대학교 산학협력단 돼지 신경 오가노이드 제조방법
WO2022256643A1 (en) * 2021-06-04 2022-12-08 The Trustees Of The University Of Pennsylvania Tissue-engineered rostral migratory stream for neuronal replacement
CN115404218B (zh) * 2022-01-13 2024-09-24 南华大学附属第一医院 一种包含胶质细胞的3d人脑类器官培养方法
EP4386384A1 (en) 2022-12-15 2024-06-19 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Potency assay for pharmaceutical products
CN116159182B (zh) * 2023-02-02 2024-09-24 中国科学院苏州纳米技术与纳米仿生研究所 用于治疗脊髓损伤的神经类器官-水凝胶体系及制备方法
CN118272307A (zh) * 2024-04-23 2024-07-02 妙顺（上海）生物科技有限公司 一种神经类器官三维培养诱导分化的方法及其应用
EP4678739A1 (en) * 2024-07-10 2026-01-14 Fundación Pública Andaluza Progreso Y Salud In vitro method for obtaining cortical brain organoids, cortical brain organoids and uses thereof

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