JPWO2020184479A1 - - Google Patents

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Publication number
JPWO2020184479A1
JPWO2020184479A1 JP2021505049A JP2021505049A JPWO2020184479A1 JP WO2020184479 A1 JPWO2020184479 A1 JP WO2020184479A1 JP 2021505049 A JP2021505049 A JP 2021505049A JP 2021505049 A JP2021505049 A JP 2021505049A JP WO2020184479 A1 JPWO2020184479 A1 JP WO2020184479A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021505049A
Other languages
Japanese (ja)
Other versions
JPWO2020184479A5 (https=
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2020184479A1 publication Critical patent/JPWO2020184479A1/ja
Publication of JPWO2020184479A5 publication Critical patent/JPWO2020184479A5/ja
Priority to JP2024177773A priority Critical patent/JP2024180505A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/4174Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biophysics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2021505049A 2019-03-08 2020-03-06 Pending JPWO2020184479A1 (https=)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024177773A JP2024180505A (ja) 2019-03-08 2024-10-10 刺激感が抑制された眼科組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019043089 2019-03-08
JP2019071396 2019-04-03
PCT/JP2020/009847 WO2020184479A1 (ja) 2019-03-08 2020-03-06 刺激感が抑制された眼科組成物

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024177773A Division JP2024180505A (ja) 2019-03-08 2024-10-10 刺激感が抑制された眼科組成物

Publications (2)

Publication Number Publication Date
JPWO2020184479A1 true JPWO2020184479A1 (https=) 2020-09-17
JPWO2020184479A5 JPWO2020184479A5 (https=) 2023-03-10

Family

ID=72427534

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021505049A Pending JPWO2020184479A1 (https=) 2019-03-08 2020-03-06
JP2024177773A Pending JP2024180505A (ja) 2019-03-08 2024-10-10 刺激感が抑制された眼科組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024177773A Pending JP2024180505A (ja) 2019-03-08 2024-10-10 刺激感が抑制された眼科組成物

Country Status (4)

Country Link
JP (2) JPWO2020184479A1 (https=)
CN (1) CN113423428A (https=)
TW (2) TW202100144A (https=)
WO (1) WO2020184479A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12601929B2 (en) * 2022-04-28 2026-04-14 Coopervision International Limited Contact lens

Citations (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4505909A (en) * 1980-09-17 1985-03-19 Bernstein Joel E Method and composition for treating and preventing irritation of the eyes
JPH07316060A (ja) * 1994-03-31 1995-12-05 Lion Corp 安定な点眼剤
JPH09132526A (ja) * 1995-11-09 1997-05-20 Lion Corp 点眼剤
JPH09169642A (ja) * 1995-12-18 1997-06-30 Lion Corp テトラヒドロゾリン含有液剤
JPH09309835A (ja) * 1996-05-21 1997-12-02 Lion Corp グリチルリチン酸アルキルエステル含有薬液
JP2000327573A (ja) * 1999-05-18 2000-11-28 Taisho Pharmaceut Co Ltd 粘膜適用組成物
JP2001302518A (ja) * 2000-02-15 2001-10-31 Rohto Pharmaceut Co Ltd 官能改善方法および官能改善剤
JP2003073303A (ja) * 2001-09-05 2003-03-12 Senju Pharmaceut Co Ltd 眼局所用液剤の清涼化作用の持続方法
JP2003146908A (ja) * 2001-11-12 2003-05-21 Rohto Pharmaceut Co Ltd 水性組成物
JP2003183157A (ja) * 2001-12-19 2003-07-03 Lion Corp 眼科用組成物
JP2004143156A (ja) * 2002-10-01 2004-05-20 Taisho Pharmaceut Co Ltd 点眼剤
JP2004175770A (ja) * 2002-11-29 2004-06-24 Rohto Pharmaceut Co Ltd ケトチフェン及びイミダゾリン化合物含有組成物
US20050271748A1 (en) * 2002-04-26 2005-12-08 Allergan, Inc. Compositions for treating hyperemia
JP2006176501A (ja) * 2004-11-26 2006-07-06 Taisho Pharmaceut Co Ltd 眼科用剤
JP2006312628A (ja) * 2005-04-08 2006-11-16 Rohto Pharmaceut Co Ltd アシタザノラスト含有水性組成物
JP2006312627A (ja) * 2005-04-08 2006-11-16 Rohto Pharmaceut Co Ltd アシタザノラスト含有組成物
WO2007108541A1 (ja) * 2006-03-23 2007-09-27 Senju Pharmaceutical Co., Ltd. キサンタンガムおよびブドウ糖を含有する眼科用組成物
JP2008024700A (ja) * 2006-06-23 2008-02-07 Rohto Pharmaceut Co Ltd ベルベリン含有水性組成物
JP2009029779A (ja) * 2007-06-29 2009-02-12 Rohto Pharmaceut Co Ltd レボカバスチン及び/又はその塩を含有する水性医薬組成物
JP2009096793A (ja) * 2007-06-01 2009-05-07 Rohto Pharmaceut Co Ltd プラノプロフェン含有水性医薬組成物
JP2011074092A (ja) * 2003-04-04 2011-04-14 Rohto Pharmaceutical Co Ltd 眼科用組成物
JP2011093897A (ja) * 2009-09-30 2011-05-12 Rohto Pharmaceutical Co Ltd 眼科用液体組成物
JP2011093898A (ja) * 2009-09-30 2011-05-12 Rohto Pharmaceutical Co Ltd 眼科組成物
JP2012144509A (ja) * 2011-01-12 2012-08-02 Saga Seiyaku Kk 多成分配合の点眼剤
JP2012206977A (ja) * 2011-03-29 2012-10-25 Rohto Pharmaceutical Co Ltd 眼科用組成物
JP2013189623A (ja) * 2012-01-30 2013-09-26 Symrise Ag 組成物
JP2013237638A (ja) * 2012-05-15 2013-11-28 Lion Corp 眼科組成物
JP2014015451A (ja) * 2012-06-14 2014-01-30 Rohto Pharmaceut Co Ltd 水性眼科組成物
WO2014050301A1 (ja) * 2012-09-27 2014-04-03 千寿製薬株式会社 水性液剤
JP2014166976A (ja) * 2013-01-31 2014-09-11 Rohto Pharmaceut Co Ltd 点眼剤
JP2015024964A (ja) * 2013-07-24 2015-02-05 学校法人近畿大学 Cyp2a13阻害剤
JP2017119669A (ja) * 2015-10-15 2017-07-06 ロート製薬株式会社 異物感改善用眼科組成物
WO2018009717A1 (en) * 2016-07-06 2018-01-11 Algomedix, Inc. Trpa1 antagonists for treatment of dry eye, ocular pain and inflammation
JP2018515538A (ja) * 2015-05-15 2018-06-14 シムライズ アーゲー 液状冷却組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9856196B2 (en) * 2012-01-05 2018-01-02 Kao Corporation Agent for reduction of sensory irritation
US20130315843A1 (en) * 2012-05-25 2013-11-28 The Procter & Gamble Company Composition for reduction of trpa1 and trpv1 sensations

Patent Citations (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4505909A (en) * 1980-09-17 1985-03-19 Bernstein Joel E Method and composition for treating and preventing irritation of the eyes
JPH07316060A (ja) * 1994-03-31 1995-12-05 Lion Corp 安定な点眼剤
JPH09132526A (ja) * 1995-11-09 1997-05-20 Lion Corp 点眼剤
JPH09169642A (ja) * 1995-12-18 1997-06-30 Lion Corp テトラヒドロゾリン含有液剤
JPH09309835A (ja) * 1996-05-21 1997-12-02 Lion Corp グリチルリチン酸アルキルエステル含有薬液
JP2000327573A (ja) * 1999-05-18 2000-11-28 Taisho Pharmaceut Co Ltd 粘膜適用組成物
JP2001302518A (ja) * 2000-02-15 2001-10-31 Rohto Pharmaceut Co Ltd 官能改善方法および官能改善剤
JP2003073303A (ja) * 2001-09-05 2003-03-12 Senju Pharmaceut Co Ltd 眼局所用液剤の清涼化作用の持続方法
JP2003146908A (ja) * 2001-11-12 2003-05-21 Rohto Pharmaceut Co Ltd 水性組成物
JP2003183157A (ja) * 2001-12-19 2003-07-03 Lion Corp 眼科用組成物
US20050271748A1 (en) * 2002-04-26 2005-12-08 Allergan, Inc. Compositions for treating hyperemia
JP2004143156A (ja) * 2002-10-01 2004-05-20 Taisho Pharmaceut Co Ltd 点眼剤
JP2004175770A (ja) * 2002-11-29 2004-06-24 Rohto Pharmaceut Co Ltd ケトチフェン及びイミダゾリン化合物含有組成物
JP2011074092A (ja) * 2003-04-04 2011-04-14 Rohto Pharmaceutical Co Ltd 眼科用組成物
JP2006176501A (ja) * 2004-11-26 2006-07-06 Taisho Pharmaceut Co Ltd 眼科用剤
JP2006312628A (ja) * 2005-04-08 2006-11-16 Rohto Pharmaceut Co Ltd アシタザノラスト含有水性組成物
JP2006312627A (ja) * 2005-04-08 2006-11-16 Rohto Pharmaceut Co Ltd アシタザノラスト含有組成物
WO2007108541A1 (ja) * 2006-03-23 2007-09-27 Senju Pharmaceutical Co., Ltd. キサンタンガムおよびブドウ糖を含有する眼科用組成物
JP2008024700A (ja) * 2006-06-23 2008-02-07 Rohto Pharmaceut Co Ltd ベルベリン含有水性組成物
JP2009096793A (ja) * 2007-06-01 2009-05-07 Rohto Pharmaceut Co Ltd プラノプロフェン含有水性医薬組成物
JP2009029779A (ja) * 2007-06-29 2009-02-12 Rohto Pharmaceut Co Ltd レボカバスチン及び/又はその塩を含有する水性医薬組成物
JP2011093897A (ja) * 2009-09-30 2011-05-12 Rohto Pharmaceutical Co Ltd 眼科用液体組成物
JP2011093898A (ja) * 2009-09-30 2011-05-12 Rohto Pharmaceutical Co Ltd 眼科組成物
JP2012144509A (ja) * 2011-01-12 2012-08-02 Saga Seiyaku Kk 多成分配合の点眼剤
JP2012206977A (ja) * 2011-03-29 2012-10-25 Rohto Pharmaceutical Co Ltd 眼科用組成物
JP2013189623A (ja) * 2012-01-30 2013-09-26 Symrise Ag 組成物
JP2013237638A (ja) * 2012-05-15 2013-11-28 Lion Corp 眼科組成物
JP2014015451A (ja) * 2012-06-14 2014-01-30 Rohto Pharmaceut Co Ltd 水性眼科組成物
WO2014050301A1 (ja) * 2012-09-27 2014-04-03 千寿製薬株式会社 水性液剤
JP2014166976A (ja) * 2013-01-31 2014-09-11 Rohto Pharmaceut Co Ltd 点眼剤
JP2015024964A (ja) * 2013-07-24 2015-02-05 学校法人近畿大学 Cyp2a13阻害剤
JP2018515538A (ja) * 2015-05-15 2018-06-14 シムライズ アーゲー 液状冷却組成物
JP2017119669A (ja) * 2015-10-15 2017-07-06 ロート製薬株式会社 異物感改善用眼科組成物
WO2018009717A1 (en) * 2016-07-06 2018-01-11 Algomedix, Inc. Trpa1 antagonists for treatment of dry eye, ocular pain and inflammation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PRETI, D. ET AL.: "Transient receptor potential ankyrin 1 (TRPA1) antagonists", PHARMACEUTICAL PATENT ANALYST, vol. 4, no. 2, JPN6020017404, 2015, pages 75 - 94, ISSN: 0005269854 *

Also Published As

Publication number Publication date
TW202100144A (zh) 2021-01-01
TW202545507A (zh) 2025-12-01
WO2020184479A1 (ja) 2020-09-17
JP2024180505A (ja) 2024-12-26
CN113423428A (zh) 2021-09-21

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