JPWO2020180591A5 - - Google Patents
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- Publication number
- JPWO2020180591A5 JPWO2020180591A5 JP2021550277A JP2021550277A JPWO2020180591A5 JP WO2020180591 A5 JPWO2020180591 A5 JP WO2020180591A5 JP 2021550277 A JP2021550277 A JP 2021550277A JP 2021550277 A JP2021550277 A JP 2021550277A JP WO2020180591 A5 JPWO2020180591 A5 JP WO2020180591A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- chimeric antigen
- antigen receptor
- domain
- dll3
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024208345A JP2025041642A (ja) | 2019-03-01 | 2024-11-29 | Ｄｌｌ３標的化キメラ抗原受容体および結合剤 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962812585P | 2019-03-01 | 2019-03-01 | |
| US62/812,585 | 2019-03-01 | ||
| US202062969976P | 2020-02-04 | 2020-02-04 | |
| US62/969,976 | 2020-02-04 | ||
| PCT/US2020/020042 WO2020180591A1 (en) | 2019-03-01 | 2020-02-27 | Dll3 targeting chimeric antigen receptors and binding agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024208345A Division JP2025041642A (ja) | 2019-03-01 | 2024-11-29 | Ｄｌｌ３標的化キメラ抗原受容体および結合剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022523781A JP2022523781A (ja) | 2022-04-26 |
| JPWO2020180591A5 true JPWO2020180591A5 (enExample) | 2023-03-06 |
| JP7702874B2 JP7702874B2 (ja) | 2025-07-04 |
Family
ID=70057267
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021550277A Active JP7702874B2 (ja) | 2019-03-01 | 2020-02-27 | Ｄｌｌ３標的化キメラ抗原受容体および結合剤 |
| JP2024208345A Pending JP2025041642A (ja) | 2019-03-01 | 2024-11-29 | Ｄｌｌ３標的化キメラ抗原受容体および結合剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024208345A Pending JP2025041642A (ja) | 2019-03-01 | 2024-11-29 | Ｄｌｌ３標的化キメラ抗原受容体および結合剤 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11673953B2 (enExample) |
| EP (1) | EP3930744A1 (enExample) |
| JP (2) | JP7702874B2 (enExample) |
| KR (1) | KR20210138574A (enExample) |
| CN (1) | CN113543799B (enExample) |
| AU (1) | AU2020231308B2 (enExample) |
| BR (1) | BR112021016984A2 (enExample) |
| CA (1) | CA3131908A1 (enExample) |
| CO (1) | CO2021011326A2 (enExample) |
| IL (1) | IL285943A (enExample) |
| MX (1) | MX2021010441A (enExample) |
| PE (1) | PE20220495A1 (enExample) |
| PH (1) | PH12021551720A1 (enExample) |
| SG (1) | SG11202108011UA (enExample) |
| WO (1) | WO2020180591A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US12247060B2 (en) | 2018-01-09 | 2025-03-11 | Marengo Therapeutics, Inc. | Calreticulin binding constructs and engineered T cells for the treatment of diseases |
| CA3105448A1 (en) | 2018-07-03 | 2020-01-09 | Elstar Therapeutics, Inc. | Anti-tcr antibody molecules and uses thereof |
| GB2597851B (en) | 2019-02-21 | 2024-05-29 | Marengo Therapeutics Inc | Antibody molecules that bind to NKP30 and uses thereof |
| EP3927744A1 (en) | 2019-02-21 | 2021-12-29 | Marengo Therapeutics, Inc. | Multifunctional molecules that bind to t cell related cancer cells and uses thereof |
| EP4084823A4 (en) | 2020-01-03 | 2024-05-15 | Marengo Therapeutics, Inc. | ANTI-TCR ANTIBODY MOLECULES AND THEIR USES |
| CN116194488A (zh) | 2020-07-21 | 2023-05-30 | 艾洛基治疗公司 | 具有增强的信号传导和活性的嵌合抗原受体和其用途 |
| CA3195114A1 (en) * | 2020-10-09 | 2022-04-14 | Martin Klatt | Compositions targeting ndc80/mhc complexes and uses thereof |
| WO2022140388A1 (en) | 2020-12-21 | 2022-06-30 | Allogene Therapeutics, Inc. | Protease-activating cd45-gate car |
| EP4284918A1 (en) | 2021-01-29 | 2023-12-06 | Allogene Therapeutics, Inc. | Knockdown or knockout of one or more of tap2, nlrc5, beta2m, trac, rfx5, rfxap and rfxank to mitigate t cell recognition of allogeneic cell products |
| TW202302650A (zh) * | 2021-05-08 | 2023-01-16 | 大陸商上海齊魯製藥研究中心有限公司 | 針對dll3的結合分子及其應用 |
| WO2023034557A1 (en) * | 2021-09-02 | 2023-03-09 | Memorial Sloan-Kettering Cancer Center | Radioligand binding to anti-dll3 antibodies for pretargeted pet imaging and therapeutic uses thereof |
| AU2022339815A1 (en) * | 2021-09-02 | 2024-03-14 | Memorial Hospital For Cancer And Allied Diseases | Antigen recognizing receptors targeting dll3 and uses thereof |
| CN114181311B (zh) * | 2021-12-20 | 2023-06-20 | 华东师范大学 | 一种全人源抗DLL3 scFv及其在CART细胞治疗中的应用 |
| WO2023192895A1 (en) | 2022-03-29 | 2023-10-05 | Allogene Therapeutics Inc. | Chimeric switch receptors for the conversion of immunesuppressive signals to costimulatory signals |
| CN119256017A (zh) * | 2022-06-23 | 2025-01-03 | 江苏恒瑞医药股份有限公司 | 特异性结合dll3和cd3的抗原结合分子及其医药用途 |
| CN119654406A (zh) | 2022-07-29 | 2025-03-18 | 艾洛基治疗公司 | 具有降低的基因表达以减轻免疫细胞识别的经工程化的细胞 |
| CN116003628A (zh) * | 2022-08-15 | 2023-04-25 | 南京博安生物技术有限公司 | 靶向人dll3抗原的全人源特异性嵌合抗原受体及其应用 |
| AU2023329484A1 (en) * | 2022-08-26 | 2025-02-20 | Juno Therapeutics, Inc. | Antibodies and chimeric antigen receptors specific for delta-like ligand 3 (dll3) |
| CN116813784B (zh) * | 2023-05-17 | 2024-03-01 | 星奕昂(上海)生物科技有限公司 | 靶向dll3的抗体及其应用 |
| CN118878683B (zh) * | 2023-07-11 | 2025-11-04 | 四川大学 | 靶向人dll3的嵌合抗原受体t细胞及其应用 |
| CN117126296B (zh) * | 2023-07-20 | 2024-02-23 | 广州默锐医药科技有限公司 | 一种car-t细胞及其构建方法和应用 |
| WO2025082340A1 (zh) * | 2023-10-16 | 2025-04-24 | 上海先博生物科技有限公司 | 一种靶向δ样配体3的CAR及应用 |
| WO2025096560A1 (en) | 2023-10-30 | 2025-05-08 | Allogene Therapeutics, Inc. | Engineered cells |
| WO2025184421A1 (en) * | 2024-02-28 | 2025-09-04 | Juno Therapeutics, Inc. | Chimeric antigen receptors and antibodies specific for delta-like ligand 3 (dll3) and related methods |
| WO2025212519A1 (en) * | 2024-04-01 | 2025-10-09 | Moonlight Bio, Inc. | Dll3 binding proteins and uses thereof |
| WO2026039940A1 (zh) * | 2024-08-19 | 2026-02-26 | 南京博安生物技术有限公司 | 一种增强型靶向dll3蛋白的嵌合抗原受体和突变体以及应用 |
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-
2020
- 2020-02-27 MX MX2021010441A patent/MX2021010441A/es unknown
- 2020-02-27 US US16/802,822 patent/US11673953B2/en active Active
- 2020-02-27 CN CN202080018238.0A patent/CN113543799B/zh active Active
- 2020-02-27 SG SG11202108011UA patent/SG11202108011UA/en unknown
- 2020-02-27 JP JP2021550277A patent/JP7702874B2/ja active Active
- 2020-02-27 PE PE2021001410A patent/PE20220495A1/es unknown
- 2020-02-27 KR KR1020217025642A patent/KR20210138574A/ko active Pending
- 2020-02-27 CA CA3131908A patent/CA3131908A1/en active Pending
- 2020-02-27 AU AU2020231308A patent/AU2020231308B2/en active Active
- 2020-02-27 PH PH1/2021/551720A patent/PH12021551720A1/en unknown
- 2020-02-27 EP EP20715560.7A patent/EP3930744A1/en active Pending
- 2020-02-27 BR BR112021016984A patent/BR112021016984A2/pt unknown
- 2020-02-27 WO PCT/US2020/020042 patent/WO2020180591A1/en not_active Ceased
-
2021
- 2021-08-27 CO CONC2021/0011326A patent/CO2021011326A2/es unknown
- 2021-08-29 IL IL285943A patent/IL285943A/en unknown
-
2023
- 2023-04-27 US US18/308,143 patent/US20230287120A1/en active Pending
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2024
- 2024-11-29 JP JP2024208345A patent/JP2025041642A/ja active Pending