JPWO2020176428A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020176428A5 JPWO2020176428A5 JP2021549625A JP2021549625A JPWO2020176428A5 JP WO2020176428 A5 JPWO2020176428 A5 JP WO2020176428A5 JP 2021549625 A JP2021549625 A JP 2021549625A JP 2021549625 A JP2021549625 A JP 2021549625A JP WO2020176428 A5 JPWO2020176428 A5 JP WO2020176428A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- alkyl
- pharmaceutically acceptable
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962810324P | 2019-02-25 | 2019-02-25 | |
| US62/810,324 | 2019-02-25 | ||
| US201962943643P | 2019-12-04 | 2019-12-04 | |
| US62/943,643 | 2019-12-04 | ||
| PCT/US2020/019552 WO2020176428A1 (en) | 2019-02-25 | 2020-02-24 | Inhibitors of integrated stress response pathway |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022521605A JP2022521605A (ja) | 2022-04-11 |
| JPWO2020176428A5 true JPWO2020176428A5 (pt) | 2023-03-06 |
Family
ID=72141533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021549625A Pending JP2022521605A (ja) | 2019-02-25 | 2020-02-24 | 統合的ストレス応答経路の阻害剤 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20200270232A1 (pt) |
| EP (1) | EP3930697A4 (pt) |
| JP (1) | JP2022521605A (pt) |
| KR (1) | KR20210134351A (pt) |
| CN (1) | CN113840597A (pt) |
| AU (1) | AU2020229748A1 (pt) |
| BR (1) | BR112021014514A2 (pt) |
| CA (1) | CA3130511A1 (pt) |
| CL (1) | CL2021002238A1 (pt) |
| IL (1) | IL285697A (pt) |
| MX (1) | MX2021010106A (pt) |
| SG (1) | SG11202107871UA (pt) |
| WO (1) | WO2020176428A1 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112020011914A2 (pt) | 2017-12-13 | 2020-11-24 | Praxis Biotech LLC | inibidores de via de resposta de tensão integrada |
| BR112020023115A2 (pt) | 2018-06-05 | 2021-02-02 | Praxis Biotech LLC | inibidores da via integrada de resposta a tensão |
| WO2020252207A1 (en) | 2019-06-12 | 2020-12-17 | Praxis Biotech LLC | Modulators of integrated stress response pathway |
| IL296220A (en) | 2020-03-11 | 2022-11-01 | Evotec Int Gmbh | Modulators for an integrated stress response pathway |
| AU2021363616A1 (en) | 2020-10-22 | 2023-06-22 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| KR20230110511A (ko) | 2020-10-22 | 2023-07-24 | 에보텍 인터내셔널 게엠베하 | 통합 스트레스 반응 경로의 조절제 |
| AU2021366303A1 (en) | 2020-10-22 | 2023-06-22 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| EP4001917A1 (en) | 2020-11-12 | 2022-05-25 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Inhibitors for use in treating liver disorders |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050197350A1 (en) * | 2003-03-31 | 2005-09-08 | Taisho Pharmaceutical Co., Ltd. | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof |
| JP4868731B2 (ja) * | 2004-11-17 | 2012-02-01 | 独立行政法人理化学研究所 | 哺乳動物培養細胞由来の無細胞タンパク質合成システム |
| TR201809547T4 (tr) * | 2012-11-09 | 2018-07-23 | Biontech Rna Pharmaceuticals Gmbh | Hücresel RNA ifadesine yönelik yöntem. |
| AU2014233520B2 (en) * | 2013-03-15 | 2019-02-21 | The Regents Of The University Of California | Modulators of the eIF2alpha pathway |
| TWI763668B (zh) * | 2016-05-05 | 2022-05-11 | 美商嘉來克生命科學有限責任公司 | 整合應激途徑之調節劑 |
| TW201808903A (zh) * | 2016-05-05 | 2018-03-16 | 嘉來克生命科學有限責任公司 | 整合應激途徑之調節劑 |
| TW201808888A (zh) * | 2016-05-05 | 2018-03-16 | 嘉來克生命科學有限責任公司 | 整合應激途徑之調節劑 |
-
2020
- 2020-02-24 EP EP20763810.7A patent/EP3930697A4/en not_active Withdrawn
- 2020-02-24 US US16/799,765 patent/US20200270232A1/en not_active Abandoned
- 2020-02-24 CA CA3130511A patent/CA3130511A1/en active Pending
- 2020-02-24 AU AU2020229748A patent/AU2020229748A1/en not_active Abandoned
- 2020-02-24 KR KR1020217030624A patent/KR20210134351A/ko unknown
- 2020-02-24 BR BR112021014514-1A patent/BR112021014514A2/pt unknown
- 2020-02-24 SG SG11202107871UA patent/SG11202107871UA/en unknown
- 2020-02-24 JP JP2021549625A patent/JP2022521605A/ja active Pending
- 2020-02-24 MX MX2021010106A patent/MX2021010106A/es unknown
- 2020-02-24 CN CN202080016491.2A patent/CN113840597A/zh active Pending
- 2020-02-24 WO PCT/US2020/019552 patent/WO2020176428A1/en unknown
-
2021
- 2021-08-18 IL IL285697A patent/IL285697A/en unknown
- 2021-08-24 CL CL2021002238A patent/CL2021002238A1/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2020122711A (ru) | Ингибиторы пути интегрированной реакции на стресс | |
| JP2020128408A (ja) | 高活性抗新生物薬及び抗増殖剤 | |
| JPWO2020176428A5 (pt) | ||
| TWI338004B (en) | Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors | |
| JP2021529814A (ja) | 化学化合物 | |
| JP2014504860A5 (pt) | ||
| RU2010153578A (ru) | Иммуноглобулины с двойными вариабельными доменами и их применение | |
| JP2013500721A5 (pt) | ||
| RU2012154210A (ru) | Связывающие il-1 белки | |
| RU2017133485A (ru) | Композиция для лечения заболеваний, связанных с ил-6 | |
| RU2018115569A (ru) | Оксаспиропроизводное, способ его получения и его применения в лекарственных средствах | |
| RU2013133811A (ru) | Иммуноглобулины с двойными вариабельными доменами и их применения | |
| RU2018121946A (ru) | Модуляторы ror-гамма | |
| RU2015143833A (ru) | СВЯЗЫВАЮЩИЕ БЕЛКИ С ДВОЙНОЙ СПЕЦИФИЧНОСТЬЮ, НАПРАВЛЕННЫЕ ПРОТИВ TNFα | |
| JP2022536663A (ja) | 統合的ストレス応答経路のモジュレーター | |
| CA2896976C (en) | Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases | |
| US9963464B2 (en) | Macrocyclic compounds | |
| JP2013507969A5 (pt) | ||
| PE20141282A1 (es) | Derivados de 8-carbamoil-2-(2,3-pirid-6-ilo di sustituido)-1,2,3,4-tetrahidroisoquinolina como agentes inductores de la apoptosis para el tratamiento del cancer y enfermedades inmunes y autoinmunes | |
| JP2016523973A5 (pt) | ||
| JP2010522184A5 (pt) | ||
| RU2010153580A (ru) | Иммуноглобулины с двумя вариабельными доменами и их применение | |
| CA3049501A1 (en) | Compositions and methods for the depletion of cd137+ cells | |
| JP2006523216A (ja) | 環状プロテインチロシンキナーゼインヒビター | |
| BR112021014514A2 (pt) | Inibidores de via de resposta integrada ao estresse |