JPWO2020154665A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2020154665A5
JPWO2020154665A5 JP2021542425A JP2021542425A JPWO2020154665A5 JP WO2020154665 A5 JPWO2020154665 A5 JP WO2020154665A5 JP 2021542425 A JP2021542425 A JP 2021542425A JP 2021542425 A JP2021542425 A JP 2021542425A JP WO2020154665 A5 JPWO2020154665 A5 JP WO2020154665A5
Authority
JP
Japan
Prior art keywords
max
emx2os
dido1
jsrp1
nbpf8
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021542425A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022518762A (ja
JP2022518762A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/015059 external-priority patent/WO2020154665A1/en
Publication of JP2022518762A publication Critical patent/JP2022518762A/ja
Publication of JPWO2020154665A5 publication Critical patent/JPWO2020154665A5/ja
Publication of JP2022518762A5 publication Critical patent/JP2022518762A5/ja
Priority to JP2024108772A priority Critical patent/JP2024133634A/ja
Pending legal-status Critical Current

Links

JP2021542425A 2019-01-24 2020-01-24 子宮内膜癌の検出 Pending JP2022518762A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024108772A JP2024133634A (ja) 2019-01-24 2024-07-05 子宮内膜癌の検出

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962796384P 2019-01-24 2019-01-24
US62/796,384 2019-01-24
PCT/US2020/015059 WO2020154665A1 (en) 2019-01-24 2020-01-24 Detecting endometrial cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024108772A Division JP2024133634A (ja) 2019-01-24 2024-07-05 子宮内膜癌の検出

Publications (3)

Publication Number Publication Date
JP2022518762A JP2022518762A (ja) 2022-03-16
JPWO2020154665A5 true JPWO2020154665A5 (https=) 2023-02-01
JP2022518762A5 JP2022518762A5 (https=) 2023-02-01

Family

ID=71735383

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021542425A Pending JP2022518762A (ja) 2019-01-24 2020-01-24 子宮内膜癌の検出
JP2024108772A Pending JP2024133634A (ja) 2019-01-24 2024-07-05 子宮内膜癌の検出

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024108772A Pending JP2024133634A (ja) 2019-01-24 2024-07-05 子宮内膜癌の検出

Country Status (8)

Country Link
US (1) US12584177B2 (https=)
EP (1) EP3914733A4 (https=)
JP (2) JP2022518762A (https=)
KR (1) KR20210119474A (https=)
CN (2) CN118910258A (https=)
AU (1) AU2020211461B2 (https=)
CA (1) CA3127329A1 (https=)
WO (1) WO2020154665A1 (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2816122A1 (en) 2008-02-15 2014-12-24 Mayo Foundation For Medical Education And Research Detecting neoplasm from a stool sample
US8361720B2 (en) 2010-11-15 2013-01-29 Exact Sciences Corporation Real time cleavage assay
ES2859645T3 (es) 2013-03-14 2021-10-04 Mayo Found Medical Education & Res Detección de neoplasia
EP4234722A3 (en) 2014-03-31 2023-09-20 Mayo Foundation for Medical Education and Research Detecting colorectal neoplasm
US10184154B2 (en) 2014-09-26 2019-01-22 Mayo Foundation For Medical Education And Research Detecting cholangiocarcinoma
CN107532124B (zh) 2015-03-27 2022-08-09 精密科学公司 检测食管疾病
CN108138235B (zh) 2015-08-31 2022-04-15 梅约医药教育及研究基金会 检测胃肿瘤
AU2016343937B2 (en) 2015-10-30 2023-01-19 Exact Sciences Corporation Multiplex amplification detection assay and isolation and detection of DNA from plasma
KR102892245B1 (ko) 2017-01-27 2025-11-27 이그젝트 싸이언스 디블롭먼트 컴패니, 엘엘씨 메틸화된 dna 분석에 의한 결장 신조직형성의 검출
US10975443B2 (en) 2017-11-30 2021-04-13 Mayo Foundation For Medical Education And Research Detecting breast cancer
US10648025B2 (en) 2017-12-13 2020-05-12 Exact Sciences Development Company, Llc Multiplex amplification detection assay II
US12584177B2 (en) 2019-01-24 2026-03-24 Mayo Foundation For Medical Education And Research Detecting endometrial cancer
EP3948292A4 (en) * 2019-04-03 2023-01-18 Mayo Foundation for Medical Education and Research DETECTION OF DUCTAL PANCREATIC CARCINOMA IN PLASMA
CA3154354A1 (en) 2019-10-31 2021-05-06 William R. Taylor Detecting ovarian cancer
US11898199B2 (en) 2019-11-11 2024-02-13 Universal Diagnostics, S.A. Detection of colorectal cancer and/or advanced adenomas
WO2021228418A1 (en) 2020-05-15 2021-11-18 Universal Diagnostics, S.L. Methods and systems for identifying methylation biomarkers
WO2022002424A1 (en) 2020-06-30 2022-01-06 Universal Diagnostics, S.L. Systems and methods for detection of multiple cancer types
AU2022213409A1 (en) * 2021-01-29 2023-08-17 Exact Sciences Corporation Detecting the presence or absence of multiple types of cancer
CN114645094B (zh) * 2022-03-21 2023-10-20 武汉凯德维斯生物技术有限公司 一种子宫内膜癌的生物标志物及其应用
CN115725734B (zh) * 2022-08-10 2023-10-13 人和未来生物科技(长沙)有限公司 Znf781基因在制备宫颈癌诊断试剂中的应用
US12606872B2 (en) 2022-11-16 2026-04-21 Universal Diagnostics, S.A. Methods for stratification and early detection of advanced adenoma and/or colorectal cancer using DNA methylation markers
CN116179698B (zh) * 2022-12-02 2025-08-01 武汉艾米森生命科技有限公司 检测目标区域的甲基化水平的试剂在制备子宫内膜癌诊断产品中的应用
WO2024136659A1 (en) * 2022-12-22 2024-06-27 Methylomics B.V. Methylation marker for cancer
CN116162707B (zh) * 2022-12-28 2024-11-29 武汉艾米森生命科技有限公司 检测cyth2基因或/和six3基因中的目标区域的甲基化水平的试剂的新应用
CN116356029B (zh) * 2023-03-29 2023-12-12 北京优迅医疗器械有限公司 Txnrd1基因甲基化水平检测在子宫内膜癌诊断和/或筛查中的应用
CN116790761B (zh) * 2023-08-22 2023-11-17 湖南宏雅基因技术有限公司 一种子宫内膜良恶性病变的生物标志物及其应用
CN118064587B (zh) * 2024-03-15 2024-09-10 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 用于子宫内膜癌早期检测的引物探针组合、甲基化检测试剂盒及其应用

Family Cites Families (135)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288609A (en) 1984-04-27 1994-02-22 Enzo Diagnostics, Inc. Capture sandwich hybridization method and composition
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5011769A (en) 1985-12-05 1991-04-30 Meiogenics U.S. Limited Partnership Methods for detecting nucleic acid sequences
US5124246A (en) 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
US5359100A (en) 1987-10-15 1994-10-25 Chiron Corporation Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
US5403711A (en) 1987-11-30 1995-04-04 University Of Iowa Research Foundation Nucleic acid hybridization and amplification method for detection of specific sequences in which a complementary labeled nucleic acid probe is cleaved
CA1340807C (en) 1988-02-24 1999-11-02 Lawrence T. Malek Nucleic acid amplification process
US5639611A (en) 1988-12-12 1997-06-17 City Of Hope Allele specific polymerase chain reaction
CA2036946C (en) 1990-04-06 2001-10-16 Kenneth V. Deugau Indexing linkers
US5494810A (en) 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
US5849481A (en) 1990-07-27 1998-12-15 Chiron Corporation Nucleic acid hybridization assays employing large comb-type branched polynucleotides
US5994069A (en) 1996-01-24 1999-11-30 Third Wave Technologies, Inc. Detection of nucleic acids by multiple sequential invasive cleavages
US5846717A (en) 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
US6872816B1 (en) 1996-01-24 2005-03-29 Third Wave Technologies, Inc. Nucleic acid detection kits
US5338671A (en) 1992-10-07 1994-08-16 Eastman Kodak Company DNA amplification with thermostable DNA polymerase and polymerase inhibiting antibody
SE501439C2 (sv) 1993-06-22 1995-02-13 Pharmacia Lkb Biotech Sätt och anordning för analys av polynukleotidsekvenser
WO1995014106A2 (en) 1993-11-17 1995-05-26 Id Biomedical Corporation Cycling probe cleavage detection of nucleic acid sequences
AU1061395A (en) 1993-11-30 1995-06-19 Mcgill University Inhibition of dna methyltransferase
US5851770A (en) 1994-04-25 1998-12-22 Variagenics, Inc. Detection of mismatches by resolvase cleavage using a magnetic bead support
AU693198B2 (en) 1994-04-25 1998-06-25 Avitech Diagnostics, Inc. Detection of mutation by resolvase cleavage
WO1996020287A2 (en) 1994-12-23 1996-07-04 Behringwerke Aktiengesellschaft Detection of nucleic acids by target-catalyzed product formation
US5882867A (en) 1995-06-07 1999-03-16 Dade Behring Marburg Gmbh Detection of nucleic acids by formation of template-dependent product
US5773258A (en) 1995-08-25 1998-06-30 Roche Molecular Systems, Inc. Nucleic acid amplification using a reversibly inactivated thermostable enzyme
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
US5965408A (en) 1996-07-09 1999-10-12 Diversa Corporation Method of DNA reassembly by interrupting synthesis
JP2001517925A (ja) 1995-12-22 2001-10-09 ベーリングウエルケ、アクティエンゲゼルシャフト 核酸の均質増幅および検出
US5985557A (en) 1996-01-24 1999-11-16 Third Wave Technologies, Inc. Invasive cleavage of nucleic acids
EP0892808B1 (en) 1996-04-12 2008-05-14 PHRI Properties, Inc. Detection probes, kits and assays
US5786146A (en) 1996-06-03 1998-07-28 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US6017704A (en) 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US6096273A (en) 1996-11-05 2000-08-01 Clinical Micro Sensors Electrodes linked via conductive oligomers to nucleic acids
US6251594B1 (en) 1997-06-09 2001-06-26 Usc/Norris Comprehensive Cancer Ctr. Cancer diagnostic method based upon DNA methylation differences
US6013459A (en) 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
DE19754482A1 (de) 1997-11-27 1999-07-01 Epigenomics Gmbh Verfahren zur Herstellung komplexer DNA-Methylierungs-Fingerabdrücke
US6063573A (en) 1998-01-27 2000-05-16 Clinical Micro Sensors, Inc. Cycling probe technology using electron transfer detection
AU753273B2 (en) 1998-02-04 2002-10-10 Variagenics, Inc. Mismatch detection techniques
US6235502B1 (en) 1998-09-18 2001-05-22 Molecular Staging Inc. Methods for selectively isolating DNA using rolling circle amplification
US7700324B1 (en) 1998-11-03 2010-04-20 The Johns Hopkins University School Of Medicine Methylated CpG island amplification (MCA)
CA2463920A1 (en) * 2001-10-16 2003-04-24 Mount Sinai Hospital Methods for detecting ovarian cancer
US7662594B2 (en) 2002-09-20 2010-02-16 New England Biolabs, Inc. Helicase-dependent amplification of RNA
EP2354253A3 (en) 2003-09-05 2011-11-16 Trustees of Boston University Method for non-invasive prenatal diagnosis
ES2432025T3 (es) 2003-10-09 2013-11-29 Epigenomics Ag Conversión mejorada de ADN con bisulfito
US20110077215A1 (en) 2005-12-07 2011-03-31 The University Of Utah Research Foundation DNA Methylation As A Target For Diagnosis And Treatment Of Chronic Lymphocytic Leukema (CLL)
TR201910868T4 (tr) 2006-02-02 2019-08-21 Univ Leland Stanford Junior Dijital analizle invazif olmayan fetal genetik tarama.
GB0700374D0 (en) 2007-01-09 2007-02-14 Oncomethylome Sciences S A NDRG family methylation markers
US20090075264A1 (en) 2007-02-02 2009-03-19 Orion Genomics Llc Gene methylation in liver cancer diagnosis
ITTO20070201A1 (it) 2007-03-19 2007-10-08 Elena Miotto Nuovi marcatori di metilazione del dna utili per la diagnosi di malattie neoplastiche
US9670552B2 (en) 2007-11-30 2017-06-06 Genomictree, Inc. Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene
US10113203B2 (en) 2007-11-30 2018-10-30 Genomictree, Inc. Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene
EP2816122A1 (en) 2008-02-15 2014-12-24 Mayo Foundation For Medical Education And Research Detecting neoplasm from a stool sample
WO2009117327A2 (en) 2008-03-15 2009-09-24 Hologic, Inc. Compositions and methods for analysis of nucleic acid molecules during amplification reactions
WO2009153667A2 (en) 2008-06-17 2009-12-23 Occure Gmbh Method for the detection of ovarian cancer
US8962247B2 (en) 2008-09-16 2015-02-24 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
WO2010062914A1 (en) 2008-11-26 2010-06-03 The Johns Hopkins University Methods for identifying cancer risk
DK2394170T3 (en) 2009-02-03 2015-07-13 Mdxhealth Sa Methods for detecting colorectal cancer
EP2308998A1 (de) * 2009-09-18 2011-04-13 Universitätsklinikum Jena Körperschaft des öffentlichen Rechts und Teilkörperschaft der Friedrich-Schiller-Universität Jena Verfahren zur frühen Diagnose von Karzinomen des Anogenitaltraktes
US20110236916A1 (en) 2010-03-26 2011-09-29 Mayo Foundation For Medical Education And Research Methods and materials for detecting colorectal neoplasm
WO2011127136A1 (en) 2010-04-06 2011-10-13 University Of Chicago Composition and methods related to modification of 5-hydroxymethylcytosine (5-hmc)
US8916344B2 (en) 2010-11-15 2014-12-23 Exact Sciences Corporation Methylation assay
US8361720B2 (en) 2010-11-15 2013-01-29 Exact Sciences Corporation Real time cleavage assay
US8715937B2 (en) 2010-11-15 2014-05-06 Exact Sciences Corporation Mutation detection assay
EP3441479B1 (en) 2011-02-02 2020-09-02 Exact Sciences Development Company, LLC Digital sequence analysis of dna methylation
GB201102014D0 (en) 2011-02-04 2011-03-23 Ucl Business Plc Method for predicting risk of developing cancer
PT105553B (pt) 2011-03-01 2020-04-20 Infogene Lda Dispositivo portátil para o armazenamento, transporte e recuperação de material biológico
EP2520661A1 (en) 2011-05-02 2012-11-07 Rheinische Friedrich-Wilhelms-Universität Bonn Blood-based gene expression signatures in lung cancer
EP2527459A1 (en) 2011-05-02 2012-11-28 Rheinische Friedrich-Wilhelms-Universität Bonn Blood-based gene detection of non-small cell lung cancer
CN103649298A (zh) 2011-05-12 2014-03-19 精密科学公司 核酸的分离
US8808990B2 (en) 2011-05-12 2014-08-19 Exact Sciences Corporation Serial isolation of multiple DNA targets from stool
WO2013070950A1 (en) 2011-11-08 2013-05-16 University Of Southern California Identification of a dna methylation marker for blood-based detection of ovarian cancer
WO2013096661A1 (en) 2011-12-22 2013-06-27 Illumina, Inc. Methylation biomarkers for ovarian cancer
DK2809810T3 (da) 2012-01-06 2020-02-03 Viomics Inc System og fremgangsmåde til påvisning i perifert blod af rna'er der er forandret af lungecancer
CA2863215C (en) 2012-01-30 2021-05-04 Exact Sciences Corporation Modification of dna on magnetic beads
WO2013142545A1 (en) 2012-03-20 2013-09-26 Exact Sciences Corporation Marker panel for detecting cancer
US9428813B2 (en) 2012-03-26 2016-08-30 The United States Of America, As Represented By The Secretary, Dept. Of Health & Human Services DNA methylation analysis for the diagnosis, prognosis and treatment of adrenal neoplasms
MX2014014356A (es) * 2012-05-24 2015-07-06 Fundació Inst D Investigació Biomédica De Bellvitge Idibell Metodo para la identificacion del origen de un cancer de origen primario desconocido.
EP2899275B1 (en) * 2012-09-19 2018-06-27 Sysmex Corporation Method for obtaining information about endometrial cancer, and marker and kit for obtaining information about endometrial cancer
US9212392B2 (en) 2012-09-25 2015-12-15 Exact Sciences Corporation Normalization of polymerase activity
US10041124B2 (en) 2013-01-14 2018-08-07 King Abdullah University Of Science And Technology Methylation biomarkers for ovarian cancer
ES2859645T3 (es) 2013-03-14 2021-10-04 Mayo Found Medical Education & Res Detección de neoplasia
WO2015066695A1 (en) 2013-11-04 2015-05-07 Exact Sciences Corporation Multiple-control calibrators for dna quantitation
EP4209600A1 (en) 2013-12-19 2023-07-12 Exact Sciences Corporation Synthetic nucleic acid control molecules
CN106232833A (zh) 2014-01-30 2016-12-14 加利福尼亚大学董事会 用于非侵入性诊断的甲基化单体型分析(monod)
EP4234722A3 (en) 2014-03-31 2023-09-20 Mayo Foundation for Medical Education and Research Detecting colorectal neoplasm
WO2015169947A1 (en) 2014-05-09 2015-11-12 Lifecodexx Ag Detection of dna that originates from a specific cell-type and related methods
US20160010081A1 (en) 2014-07-11 2016-01-14 Exact Sciences Corporation Systems, methods and kits for extracting nucleic acid from digestive fluid
US10184154B2 (en) 2014-09-26 2019-01-22 Mayo Foundation For Medical Education And Research Detecting cholangiocarcinoma
WO2016094839A2 (en) 2014-12-12 2016-06-16 Exact Sciences Corporation Compositions and methods for performing methylation detection assays
ES2879964T3 (es) 2014-12-12 2021-11-23 Exact Sciences Dev Co Llc Composiciones y métodos para realizar ensayos de detección de metilación
WO2016115354A1 (en) 2015-01-14 2016-07-21 Taipei Medical University Methods for cancer diagnosis and prognosis
US10030272B2 (en) 2015-02-27 2018-07-24 Mayo Foundation For Medical Education And Research Detecting gastrointestinal neoplasms
CN107532124B (zh) 2015-03-27 2022-08-09 精密科学公司 检测食管疾病
CN108138235B (zh) 2015-08-31 2022-04-15 梅约医药教育及研究基金会 检测胃肿瘤
WO2017067477A1 (en) * 2015-10-20 2017-04-27 Hung-Cheng Lai Methods for making diagnosis and/or prognosis of gynecologic neoplasm
AU2016343937B2 (en) 2015-10-30 2023-01-19 Exact Sciences Corporation Multiplex amplification detection assay and isolation and detection of DNA from plasma
MX391039B (es) 2016-04-07 2025-03-21 Univ Leland Stanford Junior Diagnostico no invasivo por medio de la secuenciacion del adn libre de celulas 5-hidroxi-metilado.
CA3020628A1 (en) 2016-04-14 2017-10-19 Mayo Foundation For Medical Education And Research Detecting pancreatic high-grade dysplasia
US10370726B2 (en) 2016-04-14 2019-08-06 Mayo Foundation For Medical Education And Research Detecting colorectal neoplasia
US20170321286A1 (en) 2016-05-05 2017-11-09 Exact Sciences Corporation Detection of lung neoplasia by amplification of rna sequences
CN116064796A (zh) 2016-05-05 2023-05-05 精密科学公司 通过分析甲基化dna来检测肺肿瘤
ES2915074T3 (es) 2016-05-31 2022-06-20 Translational Genomics Res Inst Métodos de marcaje molecular y bibliotecas de secuenciación
EP3488004B1 (en) 2016-07-19 2021-10-06 Exact Sciences Development Company, LLC Methylated control dna
CN109790198B (zh) 2016-09-02 2022-09-09 梅约医学教育与研究基金会 检测肝细胞癌
KR102892245B1 (ko) 2017-01-27 2025-11-27 이그젝트 싸이언스 디블롭먼트 컴패니, 엘엘씨 메틸화된 dna 분석에 의한 결장 신조직형성의 검출
CN110431241B (zh) 2017-02-28 2024-04-19 梅约医学教育与研究基金会 检测前列腺癌
IL319255A (en) 2017-08-07 2025-04-01 Univ Johns Hopkins Methods and materials for cancer assessment and treatment
US10975443B2 (en) 2017-11-30 2021-04-13 Mayo Foundation For Medical Education And Research Detecting breast cancer
US10648025B2 (en) 2017-12-13 2020-05-12 Exact Sciences Development Company, Llc Multiplex amplification detection assay II
WO2019160994A1 (en) 2018-02-14 2019-08-22 Bluestar Genomics, Inc. Methods for the epigenetic analysis of dna, particularly cell-free dna
US20210388445A1 (en) 2018-04-12 2021-12-16 Singlera Genomics, Inc. Compositions and methods for cancer and neoplasia assessment
SG11202106398WA (en) 2018-11-04 2021-07-29 Pfs Genomics Inc Methods and genomic classifiers for prognosis of breast cancer and predicting benefit from adjuvant radiotherapy
BR112021009795A2 (pt) 2018-11-27 2021-08-17 Exact Sciences Development Company, Llc métodos de caracterização e para caracterizar uma amostra, kit e composição
US12480164B2 (en) 2018-12-04 2025-11-25 EpiMedTechGlobal (EMTG) DNA methylation biomarkers for early detection of cervical cancer
WO2020118274A1 (en) 2018-12-08 2020-06-11 Pfs Genomics, Inc. Transcriptomic profiling for prognosis of breast cancer
US12584177B2 (en) 2019-01-24 2026-03-24 Mayo Foundation For Medical Education And Research Detecting endometrial cancer
EP3948292A4 (en) 2019-04-03 2023-01-18 Mayo Foundation for Medical Education and Research DETECTION OF DUCTAL PANCREATIC CARCINOMA IN PLASMA
WO2020227100A1 (en) 2019-05-03 2020-11-12 Cornell University Markers for identifying and quantifying of nucleic acid sequence mutation, expression, splice variant, translocation, copy number, or methylation changes
WO2020236939A2 (en) 2019-05-23 2020-11-26 Paradigm Diagnostics Tissue preparation using nuclease
US11396679B2 (en) 2019-05-31 2022-07-26 Universal Diagnostics, S.L. Detection of colorectal cancer
WO2020264220A1 (en) 2019-06-25 2020-12-30 The Translational Genomics Research Institute Detection and treatment of residual disease using circulating tumor dna analysis
WO2021041726A1 (en) 2019-08-27 2021-03-04 Exact Sciences Development Company, Llc Characterizing methylated dna, rna, and proteins in subjects suspected of having lung neoplasia
JP7741067B2 (ja) 2019-10-18 2025-09-17 エグザクト サイエンシーズ コーポレーション 複数の分析物を用いた糞便抗原検査
CA3154354A1 (en) 2019-10-31 2021-05-06 William R. Taylor Detecting ovarian cancer
US20220071605A1 (en) 2020-04-17 2022-03-10 Exact Sciences Development Company, Llc Sampling device and analysis of methylated dna
AU2021268333A1 (en) 2020-05-04 2022-11-24 Exact Sciences Corporation Detecting melanoma
EP4146678A4 (en) 2020-05-04 2025-08-27 Mayo Found Medical Education & Res DETECTION OF PANCREATIC NEUROENDOCRINE TUMORS
EP4189086B1 (en) 2020-07-29 2026-03-11 Exact Sciences Corporation Purification of sulfonated dna
EP4200445A4 (en) 2020-08-19 2025-08-27 Mayo Found Medical Education & Res DETECTION OF NON-HODGKIN'S LYMPHOMA
EP4281588B1 (en) 2021-01-25 2025-05-21 Université Paris Cité A method for diagnosing endometrial or ovarian carcinoma
AU2022213409A1 (en) 2021-01-29 2023-08-17 Exact Sciences Corporation Detecting the presence or absence of multiple types of cancer
IL305500A (en) 2021-03-01 2023-10-01 Pfs Genomics Inc Genomic methods and classifiers for predicting breast cancer and identifying patients who may not benefit from radiotherapy
WO2022187695A1 (en) 2021-03-05 2022-09-09 Mayo Foundation For Medical Education And Research Detecting cervical cancer
US20220349009A1 (en) 2021-04-23 2022-11-03 Mayo Foundation For Medical Education And Research Detecting esophageal disorders
US20260071277A1 (en) 2021-11-05 2026-03-12 Mayo Foundation For Medical Education And Research Compositions and methods for detecting oropharyngeal cancer

Similar Documents

Publication Publication Date Title
JPWO2020154665A5 (https=)
de la Rica et al. Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression
US12152273B2 (en) Methods and systems for detecting methylation changes in DNA samples
JP2023025184A5 (ja) メチル化dnaの分析による腫瘍の検出
JP2025063204A5 (https=)
Alonso et al. Real-time PCR designs to estimate nuclear and mitochondrial DNA copy number in forensic and ancient DNA studies
JP2024123233A5 (https=)
JPWO2019108626A5 (https=)
Tost et al. DNA methylation analysis by pyrosequencing
JP2025041764A5 (https=)
JP2020506680A5 (https=)
JP2014507164A (ja) ハプロタイプ決定のための方法およびシステム
US20200291464A1 (en) Enhanced methods of ribonucleic acid hybridization
JPWO2020112869A5 (https=)
JPWO2021041726A5 (https=)
JP2021511075A (ja) 癌におけるマイクロサテライト不安定性を検出するためのバイオマーカーパネル及び方法
RU2018122965A (ru) Улучшенный способ и набор для определения тяжести и прогрессирования периодонтального заболевания
JPWO2020206256A5 (https=)
JPWO2021087275A5 (https=)
JPWO2021226071A5 (https=)
US20150299809A1 (en) Biomarkers for Clinical Cancer Management
CN103249844B (zh) 目标核酸多标靶定量鉴定
EP4229221B1 (en) Method for parallel nucleic acid analysis
US20200040390A1 (en) Methods for Sequencing Repetitive Genomic Regions
US10907203B1 (en) DNA methylation assays for body fluid identification