JPWO2020118041A5 - - Google Patents
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- Publication number
- JPWO2020118041A5 JPWO2020118041A5 JP2021531946A JP2021531946A JPWO2020118041A5 JP WO2020118041 A5 JPWO2020118041 A5 JP WO2020118041A5 JP 2021531946 A JP2021531946 A JP 2021531946A JP 2021531946 A JP2021531946 A JP 2021531946A JP WO2020118041 A5 JPWO2020118041 A5 JP WO2020118041A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- alkylene
- alkyl
- composition
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000002947 alkylene group Chemical group 0.000 claims 8
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 125000006705 (C5-C7) cycloalkyl group Chemical group 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000004432 carbon atoms Chemical group C* 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 125000004433 nitrogen atoms Chemical group N* 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862775783P | 2018-12-05 | 2018-12-05 | |
| US62/775,783 | 2018-12-05 | ||
| PCT/US2019/064663 WO2020118041A1 (en) | 2018-12-05 | 2019-12-05 | Modified amine lipids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022514214A JP2022514214A (ja) | 2022-02-10 |
| JPWO2020118041A5 true JPWO2020118041A5 (zh) | 2023-02-13 |
Family
ID=69006051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021531946A Pending JP2022514214A (ja) | 2018-12-05 | 2019-12-05 | 修飾されたアミン脂質 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20220119341A1 (zh) |
| EP (1) | EP3891127A1 (zh) |
| JP (1) | JP2022514214A (zh) |
| KR (1) | KR20210108969A (zh) |
| CN (1) | CN113260607A (zh) |
| AU (1) | AU2019392673A1 (zh) |
| BR (1) | BR112021010853A2 (zh) |
| CA (1) | CA3121621A1 (zh) |
| CO (1) | CO2021008838A2 (zh) |
| EA (1) | EA202191559A1 (zh) |
| IL (1) | IL283622A (zh) |
| MA (1) | MA54385A (zh) |
| MX (1) | MX2021006150A (zh) |
| PH (1) | PH12021551279A1 (zh) |
| SG (1) | SG11202105367QA (zh) |
| WO (1) | WO2020118041A1 (zh) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021222287A2 (en) | 2020-04-28 | 2021-11-04 | Intellia Therapeutics, Inc. | Methods of in vitro cell delivery |
| IL303506A (en) | 2020-12-11 | 2023-08-01 | Intellia Therapeutics Inc | Polynucleotides, compounds and methods for genome editing involving deamination |
| WO2022159463A1 (en) * | 2021-01-20 | 2022-07-28 | Beam Therapeutics Inc. | Nanomaterials |
| JPWO2022168884A1 (zh) | 2021-02-04 | 2022-08-11 | ||
| KR20240017791A (ko) | 2021-04-17 | 2024-02-08 | 인텔리아 테라퓨틱스, 인크. | Dna-의존적 단백질 키나제의 억제제 및 이의 조성물 및 용도 |
| KR20240032013A (ko) | 2021-06-10 | 2024-03-08 | 인텔리아 테라퓨틱스, 인크. | 유전자 편집을 위한 내부 링커를 포함하는 변형된 가이드 rna |
| CA3235867A1 (en) | 2021-10-22 | 2023-04-27 | Munir MOSAHEB | Mrna vaccine composition |
| AU2022382975A1 (en) | 2021-11-03 | 2024-05-02 | Intellia Therapeutics, Inc. | Polynucleotides, compositions, and methods for genome editing |
| WO2023096858A1 (en) | 2021-11-23 | 2023-06-01 | Senda Biosciences, Inc. | A bacteria-derived lipid composition and use thereof |
| WO2023122080A1 (en) | 2021-12-20 | 2023-06-29 | Senda Biosciences, Inc. | Compositions comprising mrna and lipid reconstructed plant messenger packs |
| CN114213347B (zh) * | 2022-02-22 | 2022-05-20 | 中国科学院基础医学与肿瘤研究所(筹) | 一种双价可电离脂质化合物、组合物及其应用 |
| CN114213346B (zh) * | 2022-02-22 | 2022-05-20 | 中国科学院基础医学与肿瘤研究所(筹) | 一种双价可电离脂质化合物、组合物及其应用 |
| CN116354836A (zh) * | 2022-03-25 | 2023-06-30 | 深圳市新合生物医疗科技有限公司 | 阳离子脂质化合物及其制备方法和应用、以及mRNA递送系统 |
| TW202408595A (zh) | 2022-06-16 | 2024-03-01 | 美商英特利亞醫療公司 | 用於對細胞進行遺傳修飾之方法及組合物 |
| WO2024102434A1 (en) | 2022-11-10 | 2024-05-16 | Senda Biosciences, Inc. | Rna compositions comprising lipid nanoparticles or lipid reconstructed natural messenger packs |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030083272A1 (en) | 1997-09-19 | 2003-05-01 | Lahive & Cockfield, Llp | Sense mrna therapy |
| WO2006007712A1 (en) | 2004-07-19 | 2006-01-26 | Protiva Biotherapeutics, Inc. | Methods comprising polyethylene glycol-lipid conjugates for delivery of therapeutic agents |
| SG10201407996PA (en) | 2009-12-23 | 2015-01-29 | Novartis Ag | Lipids, lipid compositions, and methods of using them |
| IL300109A (en) * | 2010-06-03 | 2023-03-01 | Alnylam Pharmaceuticals Inc | Biodegradable lipids for the transfer of active substances |
| CN103748078B (zh) * | 2011-06-08 | 2016-11-09 | 夏尔人类遗传性治疗公司 | 可裂解脂质 |
| ES2887254T3 (es) * | 2013-03-08 | 2021-12-22 | Novartis Ag | Lípidos y composiciones lipídicas para el suministro de agentes activos |
| WO2015095346A1 (en) * | 2013-12-19 | 2015-06-25 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
| ES2774968T3 (es) | 2013-12-19 | 2020-07-23 | Novartis Ag | Lípidos y composiciones lipídicas para la administración de agentes activos |
| ES2949172T3 (es) | 2014-07-16 | 2023-09-26 | Novartis Ag | Método de encapsulamiento de un ácido nucleico en un hospedante de nanopartículas lipídicas |
| LT3350157T (lt) | 2015-09-17 | 2022-02-25 | Modernatx, Inc. | Junginiai ir kompozicijos terapinei medžiagai teikti intraceliuliniu būdu |
| WO2017173054A1 (en) * | 2016-03-30 | 2017-10-05 | Intellia Therapeutics, Inc. | Lipid nanoparticle formulations for crispr/cas components |
-
2019
- 2019-12-05 EP EP19828120.6A patent/EP3891127A1/en active Pending
- 2019-12-05 AU AU2019392673A patent/AU2019392673A1/en active Pending
- 2019-12-05 JP JP2021531946A patent/JP2022514214A/ja active Pending
- 2019-12-05 WO PCT/US2019/064663 patent/WO2020118041A1/en active Application Filing
- 2019-12-05 CA CA3121621A patent/CA3121621A1/en active Pending
- 2019-12-05 BR BR112021010853-0A patent/BR112021010853A2/pt unknown
- 2019-12-05 MA MA054385A patent/MA54385A/fr unknown
- 2019-12-05 US US17/299,925 patent/US20220119341A1/en active Pending
- 2019-12-05 SG SG11202105367QA patent/SG11202105367QA/en unknown
- 2019-12-05 KR KR1020217020770A patent/KR20210108969A/ko active Search and Examination
- 2019-12-05 EA EA202191559A patent/EA202191559A1/ru unknown
- 2019-12-05 MX MX2021006150A patent/MX2021006150A/es unknown
- 2019-12-05 CN CN201980086265.9A patent/CN113260607A/zh active Pending
-
2021
- 2021-06-01 PH PH12021551279A patent/PH12021551279A1/en unknown
- 2021-06-01 IL IL283622A patent/IL283622A/en unknown
- 2021-07-02 CO CONC2021/0008838A patent/CO2021008838A2/es unknown
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