JPWO2020028348A5 - - Google Patents
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- Publication number
- JPWO2020028348A5 JPWO2020028348A5 JP2021505732A JP2021505732A JPWO2020028348A5 JP WO2020028348 A5 JPWO2020028348 A5 JP WO2020028348A5 JP 2021505732 A JP2021505732 A JP 2021505732A JP 2021505732 A JP2021505732 A JP 2021505732A JP WO2020028348 A5 JPWO2020028348 A5 JP WO2020028348A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- composition
- alkyl
- concentration
- spa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 12
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 7
- 229910052739 hydrogen Inorganic materials 0.000 claims 6
- 239000001257 hydrogen Substances 0.000 claims 6
- 108010060159 Apolipoprotein E4 Proteins 0.000 claims 5
- 125000004450 alkenylene group Chemical group 0.000 claims 5
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 125000002947 alkylene group Chemical group 0.000 claims 5
- 125000000304 alkynyl group Chemical group 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 4
- 125000003342 alkenyl group Chemical group 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 208000024827 Alzheimer disease Diseases 0.000 claims 3
- 125000004419 alkynylene group Chemical group 0.000 claims 3
- 125000001475 halogen functional group Chemical group 0.000 claims 3
- 125000001424 substituent group Chemical group 0.000 claims 3
- 108700028369 Alleles Proteins 0.000 claims 2
- 150000001370 alpha-amino acid derivatives Chemical class 0.000 claims 2
- 235000008206 alpha-amino acids Nutrition 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 125000004452 carbocyclyl group Chemical group 0.000 claims 2
- 125000004122 cyclic group Chemical group 0.000 claims 2
- 125000001072 heteroaryl group Chemical group 0.000 claims 2
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 claims 1
- 238000001212 derivatisation Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862713056P | 2018-08-01 | 2018-08-01 | |
| US62/713,056 | 2018-08-01 | ||
| PCT/US2019/044114 WO2020028348A1 (en) | 2018-08-01 | 2019-07-30 | Sulfopropanoic acid derivatives for treating neurodegenerative disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021534086A JP2021534086A (ja) | 2021-12-09 |
| JPWO2020028348A5 true JPWO2020028348A5 (pt) | 2022-08-04 |
| JP7466520B2 JP7466520B2 (ja) | 2024-04-12 |
Family
ID=67587959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505732A Active JP7466520B2 (ja) | 2018-08-01 | 2019-07-30 | 神経変性障害を治療するためのスルホプロパン酸誘導体 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20220087967A1 (pt) |
| EP (2) | EP4296670A3 (pt) |
| JP (1) | JP7466520B2 (pt) |
| KR (1) | KR20210039416A (pt) |
| CN (1) | CN112867487A (pt) |
| AU (1) | AU2019314323A1 (pt) |
| BR (1) | BR112021001718A2 (pt) |
| CA (1) | CA3108182A1 (pt) |
| DK (1) | DK3829568T3 (pt) |
| EA (1) | EA202190359A1 (pt) |
| ES (1) | ES2969887T3 (pt) |
| FI (1) | FI3829568T3 (pt) |
| HR (1) | HRP20231576T1 (pt) |
| HU (1) | HUE064501T2 (pt) |
| IL (1) | IL280441A (pt) |
| LT (1) | LT3829568T (pt) |
| MX (1) | MX2021001273A (pt) |
| PL (1) | PL3829568T3 (pt) |
| PT (1) | PT3829568T (pt) |
| RS (1) | RS65022B1 (pt) |
| SG (1) | SG11202100761PA (pt) |
| SI (1) | SI3829568T1 (pt) |
| WO (1) | WO2020028348A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114315655A (zh) * | 2021-12-18 | 2022-04-12 | 青岛科技大学 | 一种吸电子基团的不饱和烷烃的磺化方法 |
| WO2024119183A1 (en) | 2022-12-02 | 2024-06-06 | Alzheon, Inc. | Methods for treating neurodegenerative disorders with tramiprosate |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5840294A (en) * | 1993-03-29 | 1998-11-24 | Queen's University At Kingston | Method for treating amyloidosis |
| CN100571701C (zh) * | 2002-12-24 | 2009-12-23 | 贝卢斯健康(国际）有限公司 | 治疗β淀粉样蛋白相关疾病的治疗性制品 |
| US10471029B2 (en) * | 2014-03-21 | 2019-11-12 | Alzheon, Inc. | Methods for treating neurological disorders |
| JP6789579B2 (ja) * | 2015-09-10 | 2020-11-25 | アルジオン， インコーポレイテッド | 特定の患者集団において神経変性障害を処置する方法 |
-
2019
- 2019-07-30 ES ES19752609T patent/ES2969887T3/es active Active
- 2019-07-30 HR HRP20231576TT patent/HRP20231576T1/hr unknown
- 2019-07-30 PL PL19752609.8T patent/PL3829568T3/pl unknown
- 2019-07-30 CA CA3108182A patent/CA3108182A1/en active Pending
- 2019-07-30 EP EP23188362.0A patent/EP4296670A3/en active Pending
- 2019-07-30 AU AU2019314323A patent/AU2019314323A1/en active Pending
- 2019-07-30 SG SG11202100761PA patent/SG11202100761PA/en unknown
- 2019-07-30 JP JP2021505732A patent/JP7466520B2/ja active Active
- 2019-07-30 PT PT197526098T patent/PT3829568T/pt unknown
- 2019-07-30 EA EA202190359A patent/EA202190359A1/ru unknown
- 2019-07-30 RS RS20231168A patent/RS65022B1/sr unknown
- 2019-07-30 US US17/264,478 patent/US20220087967A1/en active Pending
- 2019-07-30 KR KR1020217005804A patent/KR20210039416A/ko unknown
- 2019-07-30 DK DK19752609.8T patent/DK3829568T3/da active
- 2019-07-30 MX MX2021001273A patent/MX2021001273A/es unknown
- 2019-07-30 CN CN201980064442.3A patent/CN112867487A/zh active Pending
- 2019-07-30 SI SI201930675T patent/SI3829568T1/sl unknown
- 2019-07-30 BR BR112021001718-6A patent/BR112021001718A2/pt unknown
- 2019-07-30 EP EP19752609.8A patent/EP3829568B1/en active Active
- 2019-07-30 FI FIEP19752609.8T patent/FI3829568T3/fi active
- 2019-07-30 LT LTEPPCT/US2019/044114T patent/LT3829568T/lt unknown
- 2019-07-30 HU HUE19752609A patent/HUE064501T2/hu unknown
- 2019-07-30 WO PCT/US2019/044114 patent/WO2020028348A1/en active Application Filing
-
2021
- 2021-01-27 IL IL280441A patent/IL280441A/en unknown
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