JPWO2019230835A1 - マスク塗布用製剤 - Google Patents
マスク塗布用製剤 Download PDFInfo
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- JPWO2019230835A1 JPWO2019230835A1 JP2020522265A JP2020522265A JPWO2019230835A1 JP WO2019230835 A1 JPWO2019230835 A1 JP WO2019230835A1 JP 2020522265 A JP2020522265 A JP 2020522265A JP 2020522265 A JP2020522265 A JP 2020522265A JP WO2019230835 A1 JPWO2019230835 A1 JP WO2019230835A1
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- acid
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Abstract
Description
(A)揮散性有効成分
(B)ワックス剤
(C)揮散調整剤
(D)定着性向上剤
を含有するマスク塗布用製剤である。
(A)揮散性有効成分
(B)ワックス剤
(C)揮散調整剤
(D)定着性向上剤
原料として、トドマツの葉を用い、以下のようにしてその精油を得た。すなわち、トドマツ葉を圧砕式粉砕機(KYB製作所製)で粉砕し、その約50kgを、マイクロ波水蒸気蒸留装置の蒸留槽に投入した。攪拌しながら蒸留槽内の圧力を、約20KPaの減圧条件下に保持し(蒸気温度は約67℃)、1時間マイクロ波照射し精油を蒸留した。得られた精油の量は180mLであり、投入試料に対する精油の割合は、0.34%であった。
上記表1の成分(A)以外のものを加熱融解し、これに成分(A)を加えた後、型に流し込んで冷却し、スティック状に成型した。これを、図2に示すリップスティック容器に装着し、マスク塗布用製剤とした。
花粉症の症状を有する被験者に、実施例1で調製したマスク塗布用製剤(φ16mm;長さ70mm)と不織布製マスクを渡し、マスクの外側面の鼻腔周辺に塗布して使用する旨説明した後、自由に使用してもらった。その後、使用感についての効果についてアンケートを取った。この結果を表2から表8に示す。なお、これら表中、塗布回数は、マスクの横方向に4〜5cm塗布することを1回の塗布とし、これを使用に先立ち何回繰り返したかを意味し、使用実感は、「とても実感できた」、「やや実感できた」、「どちらともいえない」「あまり実感できなかった」「全く実感できなかった」の五段階での評価を訊いた結果である。
全成分を混合し、均一となるまで撹拌した。
上記表10の成分(A)以外のものを加熱融解し、これに成分(A)を加えた後、型に流し込んで冷却し、スティック状に成型した。これを、図2に示すリップスティック容器に装着し、マスク塗布用製剤とした。
花粉症の症状を有する被験者60名に、実施例3で調製した実施品2または3のマスク塗布用製剤(φ16mm;長さ70mm)と不織布製マスクを渡し、マスクの外側面の鼻腔周辺に塗布して使用する旨説明した後、自由に使用してもらった。その後、花粉症及び花症状の主な症状に対する効果実感についてアンケートを取った。結果を表11〜表14に示す。なお、表中上段の数値は当該選択肢の回答者数、下段は回答者数全体に占める当該選択肢の回答者数の割合(%)である。
スティック剤:
下記の組成で、スティック剤を調製した。
成 分 配合量(%)
揮散性有効成分 製造例1のトドマツ精油 10
dl−カンフル 1
ワックス剤 マイクロクリスタリン
ワックス 15
パラフィンワックス 15
カルナウバワックス 5
ワセリン 5
揮散調整剤 リンゴ酸ジイソステアリル 7
トリイソステアリン酸
グリセリル 15
ジカプリン酸プロピレン
グリコール 7
定着性向上剤 デカメチルシクロペンタ
シロキサン 10
その他成分 ステアリン酸イヌリン 2
精製水 5
1,3−ブチレングリコール 1
防腐剤 適 量
香 料 適 量
合 計 100
スティック剤:
下記の組成で、スティック剤を調製した。
成 分 配合量(%)
揮散性有効成分 製造例1のトドマツ精油 10
ペパーミント油 1
ワックス剤 セレシン 6
パラフィンワックス 6
キャンデリラワックス 5
揮散調整剤 1−イソステアロイル
−3−ミリストイル 22.5
グリセロール
トリ2−エチルヘキサン
酸グリセリル 11
パルミチン酸イソプロピル 22.5
ホホバ油 10
定着性向上剤 ジメチコン 4
その他成分 酸化防止剤 適 量
香 料 適 量
合 計 100
スティック剤:
下記の組成で、スティック剤を調製した。
成 分 配合量(%)
揮散性有効成分 製造例1のトドマツ精油 15
ヒノキチオール 1
ワックス剤 ポリエチレンーポリプロ
ピレンコポリマー 5
キャンデリラワックス 5
カルナウバワックス 5
ワセリン 10
揮散調整剤 2−エチルヘキサン酸セチル 10
ジイソステアリン酸
グリセリル 14.5
マカデミア油 7
定着性向上剤 ジメチコン 2
その他成分 ステアリン酸イヌリン 23
防腐剤 適 量
香 料 適 量
合 計 100
軟膏剤:
下記の組成で、軟膏剤を調製した。
成 分 配合量(%)
揮散性有効成分 製造例1のトドマツ精油 10
ワックス剤 テトラ(ヒドロキシステ
アリン酸/イソステア 5
リン酸)ジペンタエリ
スリチル
揮散調整剤 パルミチン酸2−エチル
ヘキシル 3
ステアリン酸グリセリル 1
ステアリン酸ポリグリセ
リル 1
トリ(カプリル酸/カプ
リン酸)グリセリル 0.1
ベヘニルアルコール 1
ミリスチルアルコール 1
定着性向上剤 ジメチコン 0.1
その他成分 グリセリン 3
フェノキシエタノール 適 量
メチルパラベン 適 量
ステアロイルグルタ
ミン酸ナトリウム 適 量
精製水 残 部
合 計 100
クリーム剤:
下記の組成で、クリーム剤を調製した。
成 分 配合量(%)
揮散性有効成分 製造例1のトドマツ精油 10
ワックス剤 ワセリン 5
揮散調整剤 パルミチン酸セチル 1
ステアリン酸グリセリル 1
スクワラン 16
メドウフォーム油 2
セタノール 1
定着性向上剤 ジメチコン 0.1
その他成分 グリセリン 3
トリエチルヘキサノイン 3
精製水 53.9
合 計 100
Claims (12)
- 次の成分、(A)ないし(D)
(A)揮散性有効成分
(B)ワックス剤
(C)揮散調整剤
(D)定着性向上剤
を含有することを特徴とするマスク塗布用製剤。 - 成分(A)が、アレルゲンの低減、鼻症状改善または咽症状改善を目的とする揮散性有効成分の何れかである請求項1記載のマスク塗布用製剤。
- スティック状である請求項1または2記載のマスク塗布用製剤。
- スティック状の製剤を、上部が収納物を出没可能にされたキャップ付き容器に充填してなる請求項3記載のマスク塗布用製剤。
- 成分(A)の配合量が1〜20質量%、成分(B)の配合量が1〜30質量%、成分(C)の配合量が10〜50質量%、成分(D)の配合量が0.1〜30質量%である請求項1〜4のいずれかの項記載のマスク塗布用製剤。
- 成分(A)の揮散性有効成分が、l−メントール、dl−カンフル、d−ボルネオール、カマズレン、テルピネン-4-オール、ゲラニオール、シトロネラール、ゲラ二アール、ネラール、ヒノキチオール、ペパーミント油、ユーカリ油、ヒバ油、桂皮油、ベルガモット油、テレピン油、ローズ油、ウイキョウからの精油、セージからの精油、ヒノキ科ヒノキ属、ヒノキ科スギ属及びマツ科モミ属よりなる群から選ばれた樹木からの精油である請求項1〜5のいずれかの項記載のマスク塗布用製剤。
- 成分(A)の揮散性有効成分が次の成分(A−1)及び(A−2)、
(A−1)植物からの精油、例えば、マツ科モミ属、コウヤマキ科コ
ウヤマキ属およびヒノキ科アスナロ属から選ばれた樹木の
木質部及び/または葉からの精油
(A−2)l−メントール、dl−カンフル、d−ボルネオール、ウ
イキョウ、セージ等の精油、ペパーミント油、ユーカリ油
、ヒバ油、ヒノキチオール、桂皮油、ベルガモット油、テ
レピン油、ローズ油、ウイキョウからの精油またはセージ
からの精油
を組合わせたものである請求項1〜6のいずれかの項記載のマスク塗布用製剤。 - 成分(C)が、植物油、脂肪酸エステル、脂肪酸グリコール、脂肪酸グリセリル、高級脂肪酸アルコール及び炭化水素油よりなる群から選ばれる1種または2種以上である請求項1〜7のいずれかの項記載のマスク塗布用製剤。
- 成分(D)が、流動パラフィン、流動イソパラフィン、ポリブテン、ポリイソブテン、脂肪酸ポリグリセリル、ジリノール酸エステル、ロジン、ロジン誘導体、イソステアリン酸水添ヒマシ油、(PPG−7・コハク酸)コポリマー、(ヘキシルデカン酸・セバシン酸)ジグリセリルオリゴエステル、オレフィンオリゴマー及びシリコーン油よりなる群から選ばれる1種または2種以上である請求項1〜8のいずれかの項記載のマスク塗布用製剤。
- 請求項1〜9の何れかに記載のマスク塗布用製剤をマスクに塗布し、これを口鼻部に適用することを特徴とする揮散性有効成分の吸入方法。
- アレルゲン活性低減のために行う請求項10記載の揮散性有効成分の吸入方法。
- 鼻症状改善のために行う請求項10記載の揮散性有効成分の吸入方法。
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JP2009234992A (ja) * | 2008-03-27 | 2009-10-15 | Kose Corp | スティック状化粧料 |
JP2014129266A (ja) * | 2012-12-28 | 2014-07-10 | Kao Corp | 油性化粧料 |
JP2015030704A (ja) * | 2013-08-02 | 2015-02-16 | エステー株式会社 | アレルゲン活性低減化剤及びこれを利用したアレルゲン活性低減化方法 |
JP2015117197A (ja) * | 2013-12-18 | 2015-06-25 | エステー株式会社 | 鼻症状改善剤 |
JP2016094354A (ja) * | 2014-11-12 | 2016-05-26 | 三笠製薬株式会社 | 抗炎症外用剤 |
JP2016196435A (ja) * | 2015-04-06 | 2016-11-24 | コーベビオケミア株式会社 | スキンケア用組成物 |
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CN112188886A (zh) | 2021-01-05 |
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