JPWO2019175799A5 - - Google Patents
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- JPWO2019175799A5 JPWO2019175799A5 JP2020547393A JP2020547393A JPWO2019175799A5 JP WO2019175799 A5 JPWO2019175799 A5 JP WO2019175799A5 JP 2020547393 A JP2020547393 A JP 2020547393A JP 2020547393 A JP2020547393 A JP 2020547393A JP WO2019175799 A5 JPWO2019175799 A5 JP WO2019175799A5
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- Prior art keywords
- cancer
- virus
- leishmania
- pharmaceutical composition
- represents hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 150000002431 hydrogen Chemical class 0.000 claims 14
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 13
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 12
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023202431A JP7830412B2 (ja) | 2018-03-14 | 2023-11-30 | １，２，４－オキサジアゾール化合物を用いてｔｉｇｉｔおよびｐｄ－１のシグナル伝達経路をモジュレートする方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201841009306 | 2018-03-14 | ||
| IN201841009306 | 2018-03-14 | ||
| PCT/IB2019/052039 WO2019175799A2 (en) | 2018-03-14 | 2019-03-13 | Method of modulating tigit and pd-1 signalling pathways using 1,2,4-oxadiazole compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023202431A Division JP7830412B2 (ja) | 2018-03-14 | 2023-11-30 | １，２，４－オキサジアゾール化合物を用いてｔｉｇｉｔおよびｐｄ－１のシグナル伝達経路をモジュレートする方法 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021517146A JP2021517146A (ja) | 2021-07-15 |
| JP2021517146A5 JP2021517146A5 (https=) | 2022-03-16 |
| JPWO2019175799A5 true JPWO2019175799A5 (https=) | 2022-03-16 |
| JP7417804B2 JP7417804B2 (ja) | 2024-01-19 |
Family
ID=67907451
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020547393A Active JP7417804B2 (ja) | 2018-03-14 | 2019-03-13 | １，２，４－オキサジアゾール化合物を用いてｔｉｇｉｔおよびｐｄ－１のシグナル伝達経路をモジュレートする方法 |
| JP2023202431A Active JP7830412B2 (ja) | 2018-03-14 | 2023-11-30 | １，２，４－オキサジアゾール化合物を用いてｔｉｇｉｔおよびｐｄ－１のシグナル伝達経路をモジュレートする方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023202431A Active JP7830412B2 (ja) | 2018-03-14 | 2023-11-30 | １，２，４－オキサジアゾール化合物を用いてｔｉｇｉｔおよびｐｄ－１のシグナル伝達経路をモジュレートする方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20210379024A1 (https=) |
| EP (1) | EP3768259A4 (https=) |
| JP (2) | JP7417804B2 (https=) |
| KR (1) | KR102940324B1 (https=) |
| CN (2) | CN111836621A (https=) |
| BR (1) | BR112020018555A2 (https=) |
| EA (1) | EA202091773A1 (https=) |
| MX (2) | MX2020009443A (https=) |
| WO (1) | WO2019175799A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019175799A2 (en) * | 2018-03-14 | 2019-09-19 | Aurigene Discovery Technologies Limited | Method of modulating tigit and pd-1 signalling pathways using 1,2,4-oxadiazole compounds |
| JP7623279B2 (ja) * | 2018-11-08 | 2025-01-28 | オーリジーン オンコロジー リミテッド | 小分子ｃｄ－４７阻害剤の他の抗癌剤との組み合わせ |
| CN115916348A (zh) | 2020-06-18 | 2023-04-04 | 基因泰克公司 | 使用抗tigit抗体和pd-1轴结合拮抗剂的治疗 |
| CN118871463A (zh) | 2021-07-28 | 2024-10-29 | 基因泰克公司 | 用于治疗癌症的方法和组合物 |
| TW202321308A (zh) | 2021-09-30 | 2023-06-01 | 美商建南德克公司 | 使用抗ｔｉｇｉｔ抗體、抗ｃｄ３８抗體及ｐｄ—１軸結合拮抗劑治療血液癌症的方法 |
| EP4537107A2 (en) | 2022-06-07 | 2025-04-16 | Genentech, Inc. | Method for determining the efficacy of a lung cancer treatment comprising an anti-pd-l1 antagonist and an anti-tigit antagonist antibody |
Family Cites Families (30)
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|---|---|---|---|---|
| US4172896A (en) | 1978-06-05 | 1979-10-30 | Dainippon Pharmaceutical Co., Ltd. | Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same |
| GB9217295D0 (en) | 1992-08-14 | 1992-09-30 | Wellcome Found | Controlled released tablets |
| US5541231A (en) | 1993-07-30 | 1996-07-30 | Glaxo Wellcome Inc. | Stabilized Pharmaceutical |
| GB9315856D0 (en) | 1993-07-30 | 1993-09-15 | Wellcome Found | Stabilized pharmaceutical |
| US5358970A (en) | 1993-08-12 | 1994-10-25 | Burroughs Wellcome Co. | Pharmaceutical composition containing bupropion hydrochloride and a stabilizer |
| US5811097A (en) | 1995-07-25 | 1998-09-22 | The Regents Of The University Of California | Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling |
| DK0999825T3 (da) | 1997-07-29 | 2004-02-09 | Alcon Lab Inc | Oftalmiske sammensætninger indeholdende galactomannanpolymerer og borater |
| US6110973A (en) | 1998-01-29 | 2000-08-29 | Sepracor | Methods for treating obesity and weight gain using optically pure (-)-bupropion |
| US8889112B2 (en) | 1999-09-16 | 2014-11-18 | Ocularis Pharma, Llc | Ophthalmic formulations including selective alpha 1 antagonists |
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2019
- 2019-03-13 WO PCT/IB2019/052039 patent/WO2019175799A2/en not_active Ceased
- 2019-03-13 CN CN201980018382.1A patent/CN111836621A/zh active Pending
- 2019-03-13 MX MX2020009443A patent/MX2020009443A/es unknown
- 2019-03-13 BR BR112020018555-8A patent/BR112020018555A2/pt unknown
- 2019-03-13 EP EP19767288.4A patent/EP3768259A4/en active Pending
- 2019-03-13 EA EA202091773A patent/EA202091773A1/ru unknown
- 2019-03-13 US US17/045,916 patent/US20210379024A1/en active Pending
- 2019-03-13 CN CN202410341475.0A patent/CN118236374A/zh active Pending
- 2019-03-13 KR KR1020207026540A patent/KR102940324B1/ko active Active
- 2019-03-13 JP JP2020547393A patent/JP7417804B2/ja active Active
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2020
- 2020-09-10 MX MX2023010303A patent/MX2023010303A/es unknown
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2023
- 2023-11-22 US US18/518,292 patent/US12005045B2/en active Active
- 2023-11-30 JP JP2023202431A patent/JP7830412B2/ja active Active
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