JP2020189977A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020189977A5 JP2020189977A5 JP2020107176A JP2020107176A JP2020189977A5 JP 2020189977 A5 JP2020189977 A5 JP 2020189977A5 JP 2020107176 A JP2020107176 A JP 2020107176A JP 2020107176 A JP2020107176 A JP 2020107176A JP 2020189977 A5 JP2020189977 A5 JP 2020189977A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- compound according
- oxo
- therapeutic agent
- terminated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022072939A JP2022109994A (ja) | 2014-07-17 | 2022-04-27 | マクロファージおよび他のマンノース結合ｃ型レクチン受容体高発現細胞を標的化するための化合物および組成物、ならびにそれらを使用して治療するおよび診断する方法 |
Applications Claiming Priority (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462025991P | 2014-07-17 | 2014-07-17 | |
| US62/025,991 | 2014-07-17 | ||
| US201462027193P | 2014-07-21 | 2014-07-21 | |
| US201462027220P | 2014-07-21 | 2014-07-21 | |
| US62/027,193 | 2014-07-21 | ||
| US62/027,220 | 2014-07-21 | ||
| US201462027733P | 2014-07-22 | 2014-07-22 | |
| US62/027,733 | 2014-07-22 | ||
| US201562106194P | 2015-01-21 | 2015-01-21 | |
| US62/106,194 | 2015-01-21 | ||
| US201562187064P | 2015-06-30 | 2015-06-30 | |
| US201562187132P | 2015-06-30 | 2015-06-30 | |
| US62/187,132 | 2015-06-30 | ||
| US62/187,064 | 2015-06-30 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523194A Division JP6722663B2 (ja) | 2014-07-17 | 2015-07-17 | マクロファージおよび他のマンノース結合ｃ型レクチン受容体高発現細胞を標的化するための化合物および組成物、ならびにそれらを使用して治療するおよび診断する方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022072939A Division JP2022109994A (ja) | 2014-07-17 | 2022-04-27 | マクロファージおよび他のマンノース結合ｃ型レクチン受容体高発現細胞を標的化するための化合物および組成物、ならびにそれらを使用して治療するおよび診断する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020189977A JP2020189977A (ja) | 2020-11-26 |
| JP2020189977A5 true JP2020189977A5 (https=) | 2021-07-26 |
| JP7066780B2 JP7066780B2 (ja) | 2022-05-13 |
Family
ID=55079179
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523194A Active JP6722663B2 (ja) | 2014-07-17 | 2015-07-17 | マクロファージおよび他のマンノース結合ｃ型レクチン受容体高発現細胞を標的化するための化合物および組成物、ならびにそれらを使用して治療するおよび診断する方法 |
| JP2020107176A Active JP7066780B2 (ja) | 2014-07-17 | 2020-06-22 | マクロファージおよび他のマンノース結合ｃ型レクチン受容体高発現細胞を標的化するための化合物および組成物、ならびにそれらを使用して治療するおよび診断する方法 |
| JP2022072939A Pending JP2022109994A (ja) | 2014-07-17 | 2022-04-27 | マクロファージおよび他のマンノース結合ｃ型レクチン受容体高発現細胞を標的化するための化合物および組成物、ならびにそれらを使用して治療するおよび診断する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523194A Active JP6722663B2 (ja) | 2014-07-17 | 2015-07-17 | マクロファージおよび他のマンノース結合ｃ型レクチン受容体高発現細胞を標的化するための化合物および組成物、ならびにそれらを使用して治療するおよび診断する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022072939A Pending JP2022109994A (ja) | 2014-07-17 | 2022-04-27 | マクロファージおよび他のマンノース結合ｃ型レクチン受容体高発現細胞を標的化するための化合物および組成物、ならびにそれらを使用して治療するおよび診断する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220211680A1 (https=) |
| EP (1) | EP3169792A4 (https=) |
| JP (3) | JP6722663B2 (https=) |
| CA (1) | CA2955438C (https=) |
| WO (1) | WO2016011415A2 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100196272A1 (en) | 2009-01-30 | 2010-08-05 | Neoprobe Corporation | Compositions for radiolabeling diethylenetriaminepentaacetic acid (dtpa)-dextran |
| US10806803B2 (en) | 2014-07-17 | 2020-10-20 | Ohio State Innovation Foundation | Compositions for targeting macrophages and other CD206 high expressing cells and methods of treating and diagnosis |
| WO2016011419A1 (en) * | 2014-07-17 | 2016-01-21 | Ohio State Innovation Foundation | Compositions for targeting macrophages and other cd206 high expressing cells and methods of treating and diagnosis |
| WO2018067751A1 (en) * | 2016-10-04 | 2018-04-12 | Navidea Biopharmaceuticals, Inc. | Compositions and methods for diagnosing and treating macrophage-related disorders using carbohydrate-based macromolecular carrier |
| EP3522899A4 (en) * | 2016-10-07 | 2020-05-06 | Navidea Biopharmaceuticals, Inc. | Compounds and compositions for treating leishmaniasis and methods of diagnosis and treating using same |
| MX2019004029A (es) | 2016-10-07 | 2019-09-27 | Navidea Biopharmaceuticals Inc | Compuestos y metodos para diagnosis y tratamiento de infecciones virales. |
| WO2019018815A1 (en) * | 2017-07-21 | 2019-01-24 | Navidea Biopharmaceuticals, Inc. | USE OF 99MTC-TILMANOCEPT AND ASSOCIATED MOLECULAR CONSTRUCTS FOR THE IDENTIFICATION AND DIAGNOSIS OF MALIGNANT TUMORS, AND FOR THE MONITORING OF ANTI-TUMOR THERAPEUTIC INTERVENTIONS |
| BR112021019187A2 (pt) * | 2019-03-27 | 2021-12-21 | Navidea Biopharmaceuticals Inc | Método para repolarização de um macrófago associado a tumor de m2 a m1, e, composto para repolarização de um macrófago associado a tumor de m2 a m1 |
| US20210052639A1 (en) * | 2019-08-19 | 2021-02-25 | Navidea Biopharmaceuticals, Inc. | Compositions and related methods for the ablation of m2 macrophages and myeloid derived suppressor cells |
| US20210145989A1 (en) * | 2019-09-30 | 2021-05-20 | Navidea Biopharmaceuticals, Inc. | Compositions and related methods for blocking off-target localization of mannosylated dextrans and other cd206 ligands |
| EP4076540A4 (en) | 2020-07-08 | 2024-02-21 | Navidea Biopharmaceuticals, Inc. | Synthesis of uniformly defined molecular weight mannosylated dextrans and derivatives thereof |
| CA3192041A1 (en) * | 2020-08-21 | 2022-02-24 | Resolute Science, Inc. | Compositions and methods for targeting tumor-associated macrophages |
| EP4472643A1 (en) | 2022-02-04 | 2024-12-11 | Navidea Biopharmaceuticals, Inc. | Altering net charge on mannosylated dextrans to maximize target tissue uptake and off target competitive blocking |
| JP2025517414A (ja) | 2022-05-20 | 2025-06-05 | ナビディア、バイオファーマスーティカルズ、インコーポレイテッド | 分解性リンカーを介して新規ビスホスホネート薬物ペイロードを担持するｃｄ２０６標的化薬物送達ビヒクル |
| WO2024076988A2 (en) | 2022-10-03 | 2024-04-11 | Navidea Biopharmaceuticals, Inc. | Amide linkages of sugar moieties to amine terminated leashes attached to carbohydrate polymers |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1178838B1 (en) * | 1999-05-14 | 2004-09-29 | The Regents of the University of California | Macromolecular carrier based on dextran for drug and diagnostic agent delivery |
| US8273357B2 (en) * | 2004-07-16 | 2012-09-25 | Massachusetts Institute Of Technology | Antigen-carbohydrate conjugates |
| US8343497B2 (en) * | 2008-10-12 | 2013-01-01 | The Brigham And Women's Hospital, Inc. | Targeting of antigen presenting cells with immunonanotherapeutics |
| US20100196272A1 (en) * | 2009-01-30 | 2010-08-05 | Neoprobe Corporation | Compositions for radiolabeling diethylenetriaminepentaacetic acid (dtpa)-dextran |
| US9101674B2 (en) * | 2010-03-29 | 2015-08-11 | Vib Vzw | Targeting and in vivo imaging of tumor-associated macrophages |
| WO2012171035A1 (en) * | 2011-06-10 | 2012-12-13 | University Of Washington Through Its Center For Commercialization | Carbohydrate-based compositions and methods for targeted drug delivery |
| US20130330274A1 (en) * | 2012-05-22 | 2013-12-12 | University of Virginia Patent Foundation d/b/a University of Virginia Licensing & Ventures Group | Compositions and methods for detecting and treating cancer |
| CN114377143A (zh) * | 2013-07-22 | 2022-04-22 | 康德乐健康414有限责任公司 | 用于诊断和治疗与表达cd206的细胞相关的病症的组合物、方法和药盒 |
| WO2016011419A1 (en) * | 2014-07-17 | 2016-01-21 | Ohio State Innovation Foundation | Compositions for targeting macrophages and other cd206 high expressing cells and methods of treating and diagnosis |
-
2015
- 2015-07-17 CA CA2955438A patent/CA2955438C/en active Active
- 2015-07-17 JP JP2017523194A patent/JP6722663B2/ja active Active
- 2015-07-17 EP EP15821443.7A patent/EP3169792A4/en active Pending
- 2015-07-17 WO PCT/US2015/041009 patent/WO2016011415A2/en not_active Ceased
-
2020
- 2020-06-22 JP JP2020107176A patent/JP7066780B2/ja active Active
- 2020-12-22 US US17/131,087 patent/US20220211680A1/en active Pending
-
2022
- 2022-04-27 JP JP2022072939A patent/JP2022109994A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020189977A5 (https=) | ||
| JP3268913B2 (ja) | 高分子担体 | |
| JP2020536845A5 (https=) | ||
| JP2020508985A5 (https=) | ||
| JP3270592B2 (ja) | ブロック共重合体−抗癌剤複合体医薬製剤 | |
| JP5314590B2 (ja) | カンプトテシン結合部分 | |
| JP2021073272A5 (https=) | ||
| JP5746615B2 (ja) | 癌細胞への抗体の動員のためのキメラ小分子 | |
| JP2020536847A5 (https=) | ||
| JP2022512900A5 (https=) | ||
| JP2022549510A5 (https=) | ||
| JPH05117385A (ja) | ブロツク共重合体の製造法、ブロツク共重合体及び水溶性高分子抗癌剤 | |
| EA002030B1 (ru) | Полимерные производные камптотецинов | |
| JP2021121590A5 (https=) | ||
| JP2010516675A (ja) | 治療薬剤のポリマー担体および疾病部位の抗体に基づく標的化のための認識部分 | |
| JP2012025932A (ja) | 分岐型ヘテロポリエチレングリコールおよび中間体 | |
| JP2014515406A5 (https=) | ||
| JP2003506319A (ja) | ビタミンに関連したデュアルターゲッティング治療法 | |
| JP2020519676A5 (https=) | ||
| JP2022537521A5 (https=) | ||
| CA2497167A1 (en) | Modified saccharides, conjugates thereof, and their manufacture | |
| JP2025510623A5 (https=) | ||
| US20200297693A1 (en) | Glucose conjugates of triptolide, analogs and uses thereof | |
| JP2025176137A5 (https=) | ||
| JP2007505044A5 (https=) |