KR102940324B1 - 1,2,4-옥사다이아졸 화합물을 사용하여 tigit 및 pd-1 신호전달 경로를 조절하는 방법 - Google Patents

1,2,4-옥사다이아졸 화합물을 사용하여 tigit 및 pd-1 신호전달 경로를 조절하는 방법

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KR102940324B1
KR102940324B1 KR1020207026540A KR20207026540A KR102940324B1 KR 102940324 B1 KR102940324 B1 KR 102940324B1 KR 1020207026540 A KR1020207026540 A KR 1020207026540A KR 20207026540 A KR20207026540 A KR 20207026540A KR 102940324 B1 KR102940324 B1 KR 102940324B1
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포타열 고빈단 나이르 사시쿠마
무라리드하라 라마찬드라
시싸라마야 세티 수다르샨 나레마데팔리
군달라 첸나크리시나레디
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오리진 온콜로지 리미티드
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KR1020207026540A 2018-03-14 2019-03-13 1,2,4-옥사다이아졸 화합물을 사용하여 tigit 및 pd-1 신호전달 경로를 조절하는 방법 Active KR102940324B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN201841009306 2018-03-14
IN201841009306 2018-03-14
PCT/IB2019/052039 WO2019175799A2 (en) 2018-03-14 2019-03-13 Method of modulating tigit and pd-1 signalling pathways using 1,2,4-oxadiazole compounds

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KR20200131247A KR20200131247A (ko) 2020-11-23
KR102940324B1 true KR102940324B1 (ko) 2026-03-17

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US (2) US20210379024A1 (https=)
EP (1) EP3768259A4 (https=)
JP (2) JP7417804B2 (https=)
KR (1) KR102940324B1 (https=)
CN (2) CN111836621A (https=)
BR (1) BR112020018555A2 (https=)
EA (1) EA202091773A1 (https=)
MX (2) MX2020009443A (https=)
WO (1) WO2019175799A2 (https=)

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* Cited by examiner, † Cited by third party
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WO2019175799A2 (en) * 2018-03-14 2019-09-19 Aurigene Discovery Technologies Limited Method of modulating tigit and pd-1 signalling pathways using 1,2,4-oxadiazole compounds
JP7623279B2 (ja) * 2018-11-08 2025-01-28 オーリジーン オンコロジー リミテッド 小分子cd-47阻害剤の他の抗癌剤との組み合わせ
CN115916348A (zh) 2020-06-18 2023-04-04 基因泰克公司 使用抗tigit抗体和pd-1轴结合拮抗剂的治疗
CN118871463A (zh) 2021-07-28 2024-10-29 基因泰克公司 用于治疗癌症的方法和组合物
TW202321308A (zh) 2021-09-30 2023-06-01 美商建南德克公司 使用抗tigit抗體、抗cd38抗體及pd—1軸結合拮抗劑治療血液癌症的方法
EP4537107A2 (en) 2022-06-07 2025-04-16 Genentech, Inc. Method for determining the efficacy of a lung cancer treatment comprising an anti-pd-l1 antagonist and an anti-tigit antagonist antibody

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Also Published As

Publication number Publication date
EP3768259A2 (en) 2021-01-27
WO2019175799A3 (en) 2019-10-31
CN111836621A (zh) 2020-10-27
KR20200131247A (ko) 2020-11-23
CN118236374A (zh) 2024-06-25
US20240122904A1 (en) 2024-04-18
JP7830412B2 (ja) 2026-03-16
BR112020018555A2 (pt) 2020-12-29
EP3768259A4 (en) 2022-04-06
JP2024026225A (ja) 2024-02-28
WO2019175799A2 (en) 2019-09-19
MX2020009443A (es) 2021-01-08
US20210379024A1 (en) 2021-12-09
US12005045B2 (en) 2024-06-11
JP2021517146A (ja) 2021-07-15
JP7417804B2 (ja) 2024-01-19
EA202091773A1 (ru) 2021-06-22
MX2023010303A (es) 2023-09-12

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KR102940324B1 (ko) 1,2,4-옥사다이아졸 화합물을 사용하여 tigit 및 pd-1 신호전달 경로를 조절하는 방법
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