JPWO2018151076A1 - Gel dentifrice composition and its stickiness inhibitor - Google Patents

Abstract

(A) 40 to 60% by mass of sorbitol, (B) 0.1 to 1% by mass of menthol, and (C) 0.02 to 0.2% by mass of N-ethyl-p-menthan-3-carboxamide. A gel dentifrice composition containing (B) / (C) in a mass ratio of 0.5 to 40 and containing no abrasive. Further, (D) the gel-type dentifrice composition containing eugenol in an amount of 0.01 to 0.1% by mass and the gel-type dentifrice composition containing the component (A) and containing no abrasive are used. A tackiness inhibitor, which comprises the components (B) and (C), more preferably the component (D), and has a weight ratio (B) / (C) of 0.5 to 40. ADVANTAGE OF THE INVENTION According to this invention, the stickiness is suppressed and the gel-like dentifrice composition without an abrasive which is excellent in a feeling of use and the stickiness inhibitor used for it can be provided.

Description

  The present invention relates to a gel-like dentifrice composition containing no abrasive and having excellent stickiness and a feeling of use, and a stickiness inhibitor used therefor.

  A dentifrice composition usually contains an abrasive for the purpose of removing plaque and the like, but some users prefer a dentifrice that does not contain an abrasive. For those with high risk of periodontal disease such as gingivitis and periodontitis with weak gums, dentifrice containing no abrasive is recommended to prevent adverse effects such as irritation caused by abrasive. Sometimes it is done. For this reason, there is a growing demand for dentifrice compositions such as gels that do not contain abrasives and that are less invasive to the oral mucosa even for high-risk individuals with periodontal disease and that can gently and carefully toothpaste. Yes.

  In addition to abrasives, dentifrice compositions basically contain wetting agents, binders, surfactants, and the like. For the purpose of preventing drying and maintaining good appearance as wetting agents, Polyhydric alcohol is blended. Dentifrice compositions that do not contain abrasives, especially gel-like dentifrice compositions, generally contain a relatively large amount of wetting agent in order to maintain general properties such as shape retention and suppression of liquid separation. Done. However, in the composition containing no abrasive, stickiness is generated due to an increase in the amount of the wetting agent, and the feeling of use tends to deteriorate, and the flavor expression of the fragrance may be lowered, and improvement of the feeling of use has been an issue.

  Patent Documents 1 to 3 (Japanese Patent Laid-Open No. 2006-102076, Japanese Patent Laid-Open No. 2007-176856, Japanese Patent Laid-Open No. 2006-40306) are blended with menthol and other specific fragrances to rinse, refreshing, and taste. The composition for oral cavity which the etc. improved is proposed. Although the composition for oral cavity of patent document 1 is prepared in the dentifrice gel agent which does not contain an abrasive | polishing agent, the specific examination regarding the stickiness after use is not done.

JP, 2006-102076, A JP 2007-176856 A Japanese Patent Laid-Open No. 2006-40306

  The present invention has been made in view of the above circumstances, and an object thereof is to provide a gel-like dentifrice composition containing no abrasive and excellent in feeling of use, and a stickiness inhibitor used therefor.

As a result of intensive studies to achieve the above object, the inventors of the present invention have added menthol and N-ethyl-p to an abrasive-free gel dentifrice composition containing 40% by mass or more of sorbitol as a wetting agent. It has been found that when -menthane-3-carboxamide is combined and blended at a specific ratio, stickiness due to the wetting agent is suppressed and an excellent feeling of use can be imparted. That is, in this invention, (A) It is a gel-like dentifrice composition containing 40-60 mass% of sorbitol, and further contains (B) menthol and 0.1-1 mass% ( C) N-ethyl-p-menthane-3-carboxamide in an amount of 0.02 to 0.2% by mass, and (B) / (C) as a mass ratio of 0.5 to 40, A) The stickiness due to the component is suppressed, the sticky feeling is hardly felt after use, and the refreshing feeling is improved while suppressing the irritation, and the original expression of the flavor of the preparation is well maintained. It has been found that a gel-like dentifrice composition that gives a good feeling of use can be obtained, and has led to the present invention.
In the present invention, the expression of flavor can be further improved by further adding (D) eugenol to the gel dentifrice composition, whereby the flavor can be sufficiently expressed and stickiness can be suppressed. I found it.

In the present invention, the combination of the fragrances (B) and (C) has a mass ratio of (B) / (C) within a specific range, and is surprisingly unique to the component (A) as a stickiness inhibitor. It was able to give an exceptional effect. In this case, in general, in gel dentifrice compositions containing no abrasive, stickiness may be strongly felt when the amount of wetting agent is increased. In particular, the sugar alcohol sorbitol, which is generally used as a wetting agent, is preferable in that it is less irritating, but it tends to give stickiness depending on the blending amount, and the stickiness may increase as the amount increases. On the other hand, in this invention, as shown also in the below-mentioned Example, in the gel-like dentifrice composition which does not contain an abrasive | polishing agent, (A) component is 40 mass% or more, further increased and mix | blended comparatively much. However, when a system in which the components (B) and (C) are used together in a specific ratio is mixed, stickiness is suppressed after use and hardly felt, and the stimulation by menthol is moderately suppressed and a refreshing feeling is obtained. It was improved and felt satisfactory, and the flavor development was also good.
The effect of this invention is inferior even if the general fragrance | flavor for oral cavity other than these is contained when (B) or (C) component is missing, and contains (B) and (C) component. However, it is inferior that the mass ratio of (B) / (C) is inappropriate, and in either case, the object of the present invention was not achieved.

Accordingly, the present invention provides the following gel dentifrice composition and its stickiness inhibitor.
[1]
(A) 40-60% by mass of sorbitol,
(B) 0.1 to 1% by mass of menthol and (C) 0.02 to 0.2% by mass of N-ethyl-p-menthane-3-carboxamide
A gel dentifrice composition containing (B) / (C) as a mass ratio of 0.5 to 40 and containing no abrasive.
[2]
Furthermore, (D) Gel-like dentifrice composition as described in [1] which contains 0.01-0.1 mass% of eugenol.
[3]
(D) / (C) is a gel dentifrice composition as described in [2] whose mass ratio is 0.05-5.
[4]
(A) A stickiness inhibitor for gel-like dentifrice compositions containing 40 to 60% by mass of sorbitol and not containing an abrasive,
The stickiness inhibitor which consists of (B) menthol and (C) N-ethyl-p-menthane-3-carboxamide, and (B) / (C) is 0.5-40 as mass ratio.
[5]
(A) A stickiness inhibitor for gel-like dentifrice compositions containing 40 to 60% by mass of sorbitol and not containing an abrasive,
(B) Menthol, (C) N-ethyl-p-menthane-3-carboxamide, and (D) eugenol, (B) / (C) stickiness suppression whose mass ratio is 0.5-40 Agent.
[6]
(D) / (C) is a stickiness inhibitor as described in [5] whose mass ratio is 0.05-5.

  ADVANTAGE OF THE INVENTION According to this invention, stickiness is suppressed and the gel-like dentifrice composition without an abrasive | polishing agent which is excellent in a usability | use_condition, and the stickiness inhibitor used for it can be provided. This gel dentifrice composition is low in invasiveness to the oral mucosa because it does not contain abrasives, has good general properties such as shape retention, and can be used widely for high-risk people who have developed periodontal disease. It is.

The present invention will be described in further detail below. The gel dentifrice composition of the present invention is free of abrasive, contains (A) 40% by mass or more of sorbitol, and (B) menthol and (C) N-ethyl-p-menthane-3-carboxamide. The mass ratio of (B) / (C) is contained within a specific range.
Here, the gel-like dentifrice composition of the present invention is a dentifrice composition that does not contain an abrasive but has a shape-retaining property that does not drip from the toothbrush when placed on the toothbrush.

(A) Sorbitol is a wetting agent, and for example, commercially available products such as those manufactured by Mitsubishi Shoji Foodtech Co., Ltd. can be used.
The blending amount of (A) sorbitol is 40 to 60% (mass%, the same applies hereinafter) of the whole composition, preferably 40 to 50%, and in particular from the viewpoint of the shape retention of the preparation, 42 to 50 % Is more preferable. When it is 40% or more, basic physical properties such as shape retention can be sufficiently secured with a composition not containing an abrasive. If it exceeds 60%, the stickiness becomes too strong to be suppressed, and the refreshing feeling is lowered and the flavor expression is also lowered.
In addition, in this invention, even if the compounding quantity of (A) component is 42% or more, and also 45% or more, stickiness is fully suppressed and the non-stickiness after use is excellent.

In the present invention, as a wetting agent, in addition to (A) sorbitol, other sugar alcohols and polyhydric alcohols can be blended within a range that does not interfere with the effects of the present invention. In particular, the blending amount of sugar alcohols other than sorbitol may be 20% or less, particularly 15% or less of the whole composition, or may be unblended (0%).
Polyhydric alcohol is also used as a solvent, and examples thereof include propylene glycol, polyethylene glycol having an average molecular weight of 200 to 6,000 (average molecular weight described in quasi-drug raw material specifications), ethylene glycol, and the like. The blending amount of these polyhydric alcohols is preferably 0 to 10%, particularly 4 to 10% of the whole composition.

  In the present invention, by combining (B) menthol and (C) N-ethyl-p-menthane-3-carboxamide, these act specifically on the component (A) as stickiness inhibitors. If the component (B) or (C) is absent, stickiness is not suppressed. Moreover, the feeling of refreshing after use is inferior, and flavor expression is also inferior.

(B) L-menthol is used as the menthol, and for example, a commercial product such as L-menthol manufactured by Takasago International Corporation can be used. Also, menthol-containing essential oils such as peppermint oil and peppermint oil can be used.
The blending amount of (B) menthol is 0.1 to 1% of the whole composition as a pure component, preferably 0.2 to 1%, more preferably 0.2 to 0.5%. If it is less than 0.1%, stickiness is not sufficiently suppressed, and the feeling of refreshing after use is also inferior. If it exceeds 1%, its own irritation may become too strong to perform sufficient oral cleaning.

(C) N-ethyl-p-menthane-3-carboxamide can use a synthetic product, for example, can use commercial items, such as the product made by Givodan Japan.
(C) The compounding quantity of N-ethyl-p-menthane-3-carboxamide is 0.02-0.2% of the whole composition, Preferably it is 0.05-0.1%. If it is less than 0.02%, the stickiness derived from the component (A) is not sufficiently suppressed, and the refreshing feeling after use may be inferior. If it exceeds 0.2%, flavor expression may be suppressed.

  Furthermore, (B) / (C) which shows the mixture ratio of (B) component with respect to (C) component is 0.5-40 as mass ratio, Preferably it is 2-10, More preferably, it is 3-10. . When the (B) component and the (C) component are used in an inappropriate ratio, the stimulation becomes stronger or the flavor expression is suppressed than when the (B) component alone or the (C) component alone is added. Problems such as disappearance or stickiness may not be suppressed, but if it is within the above range, the stickiness derived from the component (A) is sufficiently eliminated, and the stimulus derived from the component (B) is suppressed. It is possible to satisfactorily give a feeling of use after use while suppressing it, to improve the flavor expression, and to dramatically improve the feeling of use. When (B) / (C) is less than 0.5, the feeling of refreshing after use is inferior or the expression of flavor is suppressed. If it exceeds 40, stickiness will not be improved and stimulation will increase.

In the present invention, when (D) eugenol is further blended with the (C) component, the flavor expression is prevented from being lowered by the (C) component, and the flavor expression is further improved, while sufficiently expressing the flavor, Stickiness can be suppressed.
(D) As eugenol, for example, a commercial product such as manufactured by Toyoda Fragrance Co., Ltd. can be used. In addition, essential oils containing eugenol, such as clove oil, cassia oil, pimento oil, bay oil, basil oil, laurel oil, and the like can also be used.

  (D) As for the compounding quantity of eugenol, 0.01 to 0.1% of the whole composition is desirable as a pure part. If it is 0.01% or more, the flavor expression is sufficiently improved. When it is 0.1% or less, irritation and taste (bitterness) by itself can be sufficiently suppressed.

  Furthermore, (D) / (C) which shows the mixture ratio of (D) component with respect to (C) component has 0.05-5 as a mass ratio, More preferably, it is 0.1-2. Within this range, flavor development is further enhanced.

  In addition to the components (B) and (C), and further, the component (D), a fragrance other than these can be added to the composition of the present invention. Specifically, one or more known fragrance materials such as a natural fragrance added as a general oral fragrance, a fragrance obtained by processing a natural fragrance, a simple fragrance, and a blended fragrance can be used. The blending amount of such a fragrance is preferably 0.000001 to 2%, particularly 0.00001 to 1% of the whole composition.

Specific examples of the above general oral flavor include spearmint oil, anise oil, eucalyptus oil, winter green oil, thyme oil, sage oil, lemon oil, orange oil, cardamom oil, coriander oil, mandarin oil, lime oil. , Natural fragrances such as lavender oil, rosemary oil, camomile oil, caraway oil, marjoram oil, lemongrass oil, origanum oil, pine needle oil, neroli oil, rose oil, jasmine oil, Iris concrete, absolute rose, orange flower , Fragrances obtained by processing these natural fragrances (pre-reservoir cut, rear reservoir cut, fractional distillation, liquid-liquid extraction, essence, powder fragrance, etc.), carvone, anethole, cineol, methyl salicylate, 3-l-ment Xipropane-1,2-diol, thymol, linalool, linalyl acetate , Limonene, menthone, menthyl acetate, pinene, octyl aldehyde, citral, pulegone, carbyl acetate, anisaldehyde, ethyl acetate, ethyl butyrate, allyl cyclohexane propionate, methyl anthranilate, ethyl methyl phenyl glycidate, Single flavors such as vanillin, undecalactone, hexanal, propyl alcohol, butanol, isoamyl alcohol, hexenol, dimethyl sulfide, cycloten, furfural, trimethylpyrazine, ethyl lactate, methyl lactate, ethyl thioacetate, strawberry flavor, apple flavor, Banana Flavor, Pineapple Flavor, Grape Flavor, Mango Flavor, Butter Flavor, Mi Click flavor, fruit mix flavors, include the blended fragrance such as tropical fruit flavors.
In addition, when the component (B), (C) or (D) is contained in the fragrance, the amount of these components is included in the blending amount of the component (B), (C) or (D) described above. , And can be used within the range of the amount of each component.

  The gel-like dentifrice composition of the present invention does not contain an abrasive, but may contain other known components in addition to the above components as long as the effects of the present invention are not hindered. For example, a binder, a surfactant, a sweetener, an antiseptic, a colorant, various active ingredients, a pH adjuster, and the like can be blended, and these ingredients can be mixed with water to produce by a known method.

  As binder, organic binders such as sodium polyacrylate, xanthan gum, sodium alginate, propylene glycol alginate, sodium carboxymethylcellulose, hydroxyethylcellulose, carboxyvinyl polymer, guar gum, gelatin, crystalline cellulose, polyvinyl alcohol, polyvinylpyrrolidone, etc. Inorganic binders such as gelling silica, gelling aluminum silica, montmorillonite, kaolin and bentonite can be used, and one or more of these can be used. The compounding amount of the binder is usually 0.1 to 13%, particularly 1.1 to 10% of the whole composition. In particular, the blending amount of the organic binder is preferably 0.1 to 5% of the entire composition, and the blending amount of the inorganic binder is preferably 1 to 8%, particularly 1 to 5% of the entire composition.

Examples of the surfactant include an anionic surfactant, a nonionic surfactant, a cationic surfactant, and an amphoteric surfactant. Specifically, the following can be used.
Anionic surfactants; alkyl sulfates such as sodium lauryl sulfate and sodium myristyl sulfate; sodium lauryl sulfoacetate; sodium α-olefin sulfonate; nonionic surfactants; polyoxyethylene fatty acid esters such as polyoxyethylene hydrogenated castor oil; Polyoxyethylene higher alcohol ether such as polyoxyethylene lauryl ether, sugar fatty acid ester such as sucrose fatty acid ester, sugar alcohol fatty acid ester, sorbitan fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester cationic surfactant; distearyl chloride Methylammonium, stearyldimethylbenzylammonium chloride amphoteric surfactants; 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolini The amount of betaine surfactants such as Mubetain is usually from 0.6 to 7% of the total composition, in particular from 1.1 to 5%. Moreover, the compounding quantity of anionic surfactant, especially alkyl sulfates, such as sodium lauryl sulfate, is 0.1 to 3% of the whole composition, and 0.2 to 2% is especially preferable.

Examples of the sweetening agent include saccharin sodium, aspartame, stevioside, stevia extract, neohesperidyl dihydrochalcone, and perilartin.
Examples of the preservative include paraoxybenzoic acid esters such as butylparaben and ethylparaben, benzoic acid such as sodium benzoate, and salts thereof.
As the colorant, Blue No. 1, Yellow No. 4, Green No. 3, and the like can be blended in a normal amount.

  Examples of active ingredients include known ingredients that are usually blended in dentifrice compositions, such as fluorides, bactericides, anti-inflammatory agents, enzymes, plant extracts, anticalculus agents, anti-plaque agents, and the like of the present invention. An effective amount can be blended within a range that does not interfere with the effect. Specifically, fluorides such as sodium fluoride, stannous fluoride, strontium fluoride, sodium monofluorophosphate, sodium salt of orthophosphoric acid, tranexamic acid, epsilon aminocaproic acid, tocopherol acetate, α-bisabolol , Dihydrocholesterol, chlorohexidine salts, azulene, glycyrrhetin, glycyrrhetinic acid, glycyrrhizic acid or salts thereof, copper compounds such as copper chlorophyllin sodium, chlorophyll, copper gluconate, chelating phosphate compounds such as glycerophosphate, hydroxamic acid or derivatives thereof , Sodium tripolyphosphate, methoxyethylene, epidihydrocholesterin, isopropylmethylphenol, benzethonium chloride, cetylpyridinium chloride, allantochlorohydroxyal Chloride, ascorbic acid or a salt thereof, ascorbic acid phosphoric acid ester or its salt, lysozyme chloride, trichlorocarbanilide, zinc citrate, and the like bark extract. Of these, tocopherol acetate and isopropylmethylphenol are preferable in terms of effects, and the blending amount may be an effective amount, but 0.01 to 2%, particularly 0.05 to 1% of the entire composition is preferable.

  Examples of the pH adjuster include organic acids such as citric acid, lactic acid and malic acid or salts thereof, phosphoric acid or salts thereof, and inorganic compounds such as hydrochloric acid, sodium hydroxide and potassium hydroxide.

  20-60% of the whole composition is preferable, and, as for the moisture content of the gel-like dentifrice composition of this invention, 30-50% is more preferable.

Further, the stickiness inhibitor of the present invention is (A) a stickiness inhibitor for a gel dentifrice composition containing 40-60% sorbitol and not containing an abrasive, comprising (B) menthol and (C ) N-ethyl-p-menthane-3-carboxamide, more preferably (D) eugenol, wherein (B) / (C) has a mass ratio of 0.5 to 40.
Here, the components (B) and (C), more preferably the component (D) are effective components for suppressing stickiness, and the components (B) and (C) are used in combination at a specific blending ratio (mass ratio). It can be used as a stickiness inhibitor composed of only the above-mentioned active ingredient, which is blended into the gel dentifrice composition. Further, these components can be used as stickiness suppressing agents for gel dentifrice compositions by adding these components as active ingredients for stickiness suppression and further adding other components.
In this case, the details of the components (A), (B) and (C), further the component (D), the blending amount and blending ratio thereof, and other components are all the same as the gel dentifrice composition. It is the same.

  EXAMPLES Hereinafter, although an Example and a comparative example are shown and this invention is demonstrated concretely, this invention is not restrict | limited to the following Example. In the following examples, “%” means “% by mass” unless otherwise specified.

[Examples and Comparative Examples]
Gel dentifrice compositions having the compositions shown in Tables 1 to 3 were prepared by a conventional method.
For preparation of the gel dentifrice composition, sorbitol (manufactured by Mitsubishi Corporation Foodtech), menthol (manufactured by Takasago International Corporation, L-menthol), N-ethyl-p-menthane-3-carboxamide ( Gibodan Japan Co., Ltd., trade name: WS-3), Eugenol (Toyotama Fragrance Co., Ltd.) was used. The blending amount is a pure amount.
The other ingredients were used as standard products for the outer general standards (quasi-drug raw material standards), and the purified water was used as the standard for the cosmetic base (cosmetic raw material standards). The fragrance A used is a general oral fragrance, and does not include menthol, N-ethyl-p-menthane-3-carboxamide, and eugenol. The composition of perfume A is shown below.
Composition of perfume A;
Cineol 20 parts by weight Limonene 10
Mentone 20
Carvone 10
Anethol 20
Ethanol 20
Total 100 parts by mass

The following evaluation was performed about the usability | use_condition of the prepared gel-like dentifrice composition.
10 subjects took 1g of gel dentifrice composition on a toothbrush (Lion Corporation, Denta Systemma, Lion Habrush, Regular), brushed for 3 minutes, and then felt non-sticky and unstimulated in the oral cavity. For each of the refreshing feeling and flavor expression (good flavor expression), a sensory test was performed by relative evaluation or absolute evaluation, and judged according to the following score criteria. The average value of the scores of 10 people was calculated and evaluated according to the following evaluation criteria. The results are shown in Tables 1-3.
Here, “stickiness” is a sensation in which the sweetness (moist quality) derived from the wetting agent remains in the mouth, and “stimulation” is a sensation of irritation in the mouth.

(I) No stickiness (rating)
4 points: No stickiness 3 points: Little stickiness 2 points: Stickiness 1 point: Very sticky (Evaluation criteria)
Average point of non-stickiness ◎: 3.5 points or more and 4.0 points or less ○: 3.0 points or more and less than 3.5 points △: 2.0 points or more and less than 3.0 points ×: 1.0 points or more and 2 Less than 0 points

(Ii) No stimulation (score)
4 points: I do not feel any stimulation 3 points: I hardly feel stimulation 2 points: I feel stimulation 1 point: I feel stimulation very much (evaluation criteria)
Average point of no stimulation ◎: 3.5 points or more and 4.0 points or less ○: 3.0 points or more and less than 3.5 points △: 2.0 points or more and less than 3.0 points ×: 1.0 points or more and 2 Less than 0 points

(Iii) Refreshing feeling (score)
4 points: I feel a refreshing feeling 3 points: I feel a feeling of refreshing 2 points: I feel a feeling of refreshing slightly 1 point: I do not feel a feeling of refreshing at all (evaluation criteria)
Average point of refreshing feeling ◎: 3.5 point or more and 4.0 point or less ○: 3.0 point or more and less than 3.5 point Δ: 2.0 point or more and less than 3.0 point ×: 1.0 point or more and 2. Less than 0

(Iv) Flavor expression (score)
4 points: very good flavor expression 3 points: good flavor expression 2 points: slightly good flavor expression 1 point: poor flavor expression (evaluation criteria)
Average score for flavor development ◎: 3.5 to 4.0 points ○: 3.0 to less than 3.5 points △: 2.0 to less than 3.0 points ×: 1.0 to 2 Less than 0 points

  As shown in Tables 1 and 2, the gel-like dentifrice compositions (Examples) of the present invention were excellent in non-stickiness, non-irritated, refreshing feeling and flavor expression. On the other hand, as shown in Table 3, when the components (B) and / or (C) were absent, the non-stickiness was inferior, and the refreshing feeling and flavor expression were also inferior (Comparative Examples 1 to 3). Moreover, when (B) / (C) was too large, even if it contained (B) and (C) component, the non-stickiness was inferior and irritation | stimulation became strong. The flavor expression was also suppressed (Comparative Example 4).

[Example 21] Gel dentifrice (A) Sorbitol 40%
(B) Menthol 0.25
(C) N-ethyl-p-menthane-3-carboxamide 0.1
(D) Clove oil (manufactured by Taiyo Fragrance Co., Ltd.) 0.02 as eugenol
Tocopherol acetate 0.6
Tranexamic acid 0.05
Isopropyl methylphenol 0.05
Sodium fluoride 0.2
Xanthan gum 1.0
Alginic acid propylene glycol ester 0.1
Thickening silica 6.0
Saccharin sodium 0.1
Propylene glycol 3.0
Carrageenan 0.8
Polyethylene glycol 4000 0.4
Lauroylmethyl taurine sodium 0.6
Polyoxyethylene (20) hydrogenated castor oil 1.2
Polyoxyethylene (5) stearyl ether 1.2
Sodium dihydrogen phosphate 0.5
Sodium sulfate 1.0
Sodium hydroxide 0.1
Fragrance A 0.5
Purified water balance
Total 100%
(B) / (C) = 2.5, (D) / (C) = 0.2

[Example 22] Gel dentifrice (A) Sorbitol 45%
(B) Menthol 0.25
(C) N-ethyl-p-menthane-3-carboxamide 0.15
Tocopherol acetate 0.6
Magnesium ascorbate phosphate 0.3
Isopropyl methylphenol 0.05
Sodium monofluorophosphate 0.7
Xanthan gum 1.0
Alginic acid propylene glycol ester 0.1
Thickening silica 6.0
Saccharin sodium 0.1
Propylene glycol 5.0
Carrageenan 0.8
Polyethylene glycol 4000 0.4
Lauroylmethyl taurine sodium 0.6
Polyoxyethylene (20) hydrogenated castor oil 1.2
Polyoxyethylene (5) stearyl ether 1.2
Sodium dihydrogen phosphate 0.5
Sodium sulfate 1.0
Sodium hydroxide 0.3
Citric acid 0.1
Fragrance A 0.5
Purified water balance
Total 100%
(B) / (C) = 1.67

[Example 23] Gel dentifrice (A) Sorbitol 40%
(B) Menthol 0.2
(C) N-ethyl-p-menthane-3-carboxamide 0.02
Cetylpyridinium chloride 0.02
Sodium fluoride 0.2
Sodium alginate 0.6
Thickening silica 4.5
Saccharin sodium 0.1
Propylene glycol 5.0
Xanthan gum 1.1
Polyoxyethylene (20) hydrogenated castor oil 3.0
Fragrance A 0.3
Purified water balance
Total 100%
(B) / (C) = 10

[Example 24] Gel dentifrice (A) Sorbitol 40%
(B) Menthol 0.6
(C) N-ethyl-p-menthane-3-carboxamide 0.06
(D) Eugenol 0.05
Tocopherol acetate 0.1
Tranexamic acid 0.05
Isopropylmethylphenol 0.1
Sodium fluoride 0.2
Lauroyl sarcosine sodium 0.2
Sodium alginate 0.6
Thickening silica 6.0
Saccharin sodium 0.1
Propylene glycol 3.5
Xanthan gum 1.4
Polyethylene glycol 4000 1.0
Sodium lauryl sulfate 1.3
Polyoxyethylene (20) hydrogenated castor oil 1.5
Polyoxyethylene (5) stearyl ether 1.5
Sodium sulfate 1.0
Fragrance A 1.0
Purified water balance
Total 100%
(B) / (C) = 10, (D) / (C) = 0.83

Claims (6)

(A) 40-60% by mass of sorbitol,
(B) 0.1 to 1% by mass of menthol and (C) 0.02 to 0.2% by mass of N-ethyl-p-menthane-3-carboxamide
A gel dentifrice composition containing (B) / (C) as a mass ratio of 0.5 to 40 and containing no abrasive.   Furthermore, the gel-like dentifrice composition of Claim 1 which contains 0.01-0.1 mass% of (D) eugenol.   The gel-like dentifrice composition according to claim 2, wherein (D) / (C) is 0.05 to 5 as a mass ratio. (A) A stickiness inhibitor for gel-like dentifrice compositions containing 40 to 60% by mass of sorbitol and not containing an abrasive,
The stickiness inhibitor which consists of (B) menthol and (C) N-ethyl-p-menthane-3-carboxamide, and (B) / (C) is 0.5-40 as mass ratio. (A) A stickiness inhibitor for gel-like dentifrice compositions containing 40 to 60% by mass of sorbitol and not containing an abrasive,
(B) Menthol, (C) N-ethyl-p-menthane-3-carboxamide, and (D) eugenol, (B) / (C) stickiness suppression whose mass ratio is 0.5-40 Agent.   (D) / (C) is 0.05-5 as mass ratio, The stickiness inhibitor of Claim 5.