JP7388126B2 - Oral composition - Google Patents

Description

The present invention relates to an oral composition that improves the retention of potassium nitrate in the oral cavity and has an excellent long-lasting effect of suppressing hypersensitivity.

In the oral cavity, when the tooth root surface is exposed, stimulation is transmitted from the dentinal tubules on the tooth root surface to the nerves, causing hypersensitivity. Potassium nitrate, which has a neurodepressant effect, is an active ingredient that has an effect of suppressing hypersensitivity, and it is known that this exists as a potassium ion to exert a neurodepressant effect.
In order to enhance the hypersensitivity suppressing effect of potassium nitrate, it is important to increase the elution amount of potassium ions, but on the other hand, it is effective to maintain the hypersensitivity suppressing effect even after application to the oral cavity. It is. In order to sustain the hypersensitivity suppressing effect of potassium nitrate, it is considered important to retain potassium ions in the oral cavity.

As a prior art, Patent Document 1 (Japanese Unexamined Patent Publication No. 2016-222579) discloses that by using a specific amino acid type anionic surfactant and a nonionic surfactant in combination, the elution of potassium ions from potassium nitrate is improved. In Patent Document 2 (Japanese Unexamined Patent Publication No. 2017-141178), it was proposed that the foaming performance could be improved by adding α-olefin sulfonate and sucralose to a dentifrice composition containing potassium nitrate. Although it has been proposed that potassium ion retention can be improved, there have been no reports on the retention of potassium ions, and the sustainability of the hypersensitivity suppressing effect of potassium nitrate is unknown.

Japanese Patent Application Publication No. 2016-222579 JP 2017-141178 Publication

The present invention was made in view of the above circumstances, and an object of the present invention is to provide an oral composition that improves the retention of potassium nitrate in the oral cavity and has an excellent long-lasting effect of suppressing hypersensitivity.

As a result of intensive studies to achieve the above object, the present inventors identified an anionic surfactant α-olefin sulfonate and a nonionic surfactant in an oral composition containing potassium nitrate. When used in combination with a cationic polymer substance, the retention of potassium ions increases, the retention of potassium nitrate in the oral cavity is improved, the sustainability of the hypersensitivity suppressing effect is improved, and foaming is ensured. I found out that it can also be done. That is, according to the present invention, (A) potassium nitrate, (B) α-olefin sulfonate, (C) nonionic surfactant, and (D) cationic polymeric substance are contained; ) The mass ratio of (B)/(C) indicating the quantity ratio of the components is 0.02 to 0.2, thereby increasing the retention of potassium ions and improving the retention of the component (A) in the oral cavity. The present inventors have discovered that it is possible to provide an oral composition that has an excellent long-lasting effect of suppressing hypersensitivity and also foams well, leading to the present invention.

More specifically, even if potassium nitrate was blended into the oral composition and an anionic surfactant was further blended to ensure foaming, the potassium nitrate could not be sufficiently retained in the oral cavity. ), an anionic surfactant (B) α-olefin sulfonate and (C) a nonionic surfactant are used in combination at a mass ratio of (B)/(C) within a specific range; By further incorporating (D) a cationic polymer substance into the system, the above-mentioned special effects could be provided. In this case, when an anionic surfactant was used in combination with component (A) to ensure foaming, the retention of potassium ions in component (A) on the tooth surface decreased, resulting in poor retention in the oral cavity. However, when component (A) is combined with components (B), (C), and (D), the mass ratio of (B)/(C) is within the above specified range, and (B), (C), and ( D) The components interact specifically, and the anionic surfactant increases the retention of the component (A) in the oral cavity without deteriorating the retention of potassium ions as described above, and the hypersensitivity suppressing effect is enhanced in the oral cavity. The formulation was able to last for a long time after use. As a result, in the present invention, in the oral composition containing the component (A), the component (A) is sufficiently retained in the oral cavity while ensuring satisfactory foaming, and has an excellent hypersensitivity suppressing effect that persists even after use. was able to be granted.
As is clear from the results of Examples and Comparative Examples described below, the effects of the present invention are achieved by appropriately combining component (A) with components (B), (C), and (D). , (B), (C) or (D), the effect is poor, and when the (B)/(C) ratio is inappropriate, the effect is also poor.
As shown in the Comparative Examples, in Comparative Examples 1 and 3 in which component (C) or (D) was not blended, the retention of potassium nitrate in the oral cavity and the durability of the hypersensitivity suppressing effect were poor, and the component (B) In Comparative Example 6, which does not contain potassium nitrate, even though sodium lauryl sulfate, an anionic surfactant, and components (C) and (D) are blended, the effect of suppressing potassium nitrate's retention in the oral cavity and hypersensitivity is low. The durability was poor. Furthermore, even if components (B), (C), and (D) are blended with component (A), Comparative Example 4, in which the mass ratio of (B)/(C) is too small, has poor foaming. In Comparative Example 5, where the value was too large, the retention of potassium nitrate in the oral cavity and the durability of the hypersensitivity suppressing effect were poor. In addition, in Comparative Example 2 in which no anionic surfactant was blended, although the retention of potassium nitrate in the oral cavity and the effect of suppressing hypersensitivity were good, there was almost no foaming. In contrast, an oral cavity composition in which components (A), (B), (C), and (D) of the present invention shown in Examples are blended and the mass ratio of (B)/(C) is within a specific range. The product had excellent retention of potassium nitrate in the oral cavity and durability of the hypersensitivity suppressing effect, and foamed well.

Therefore, the present invention provides the following oral composition.
[1]
(A) Potassium nitrate,
(B) α-olefin sulfonate,
Contains (C) a nonionic surfactant and (D) a cationic polymer substance, where (B)/(C) indicating the quantitative ratio of components (B) and (C) is from 0.02 to 0.02 as a mass ratio. An oral composition characterized in that the molecular weight is 0.2.
[2]
(B) The oral composition according to [1], wherein the α-olefin sulfonate has 14 to 16 carbon atoms.
[3]
(C) The nonionic surfactant according to [1] or [2], wherein the nonionic surfactant is one or more selected from polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl ether, fatty acid glycerin ester, and alkyl glycoside. Oral composition.
[4]
(D) The cationic polymeric substance is made of a cationic cellulose polymer, a homopolymer of dimethyldiallylammonium, a copolymer of dimethyldiallylammonium chloride and a polymerizable monomer having an ethylenically unsaturated hydrocarbon group, and a cationized polymethacrylate. The oral composition according to any one of [1] to [3], which is one or more selected types.
[5]
(D) The oral composition according to [4], wherein the cationic polymeric substance is hydroxyethyl cellulose dimethyl diallylammonium chloride.
[6]
Contains 1 to 10% by mass of component (A), 0.1 to 0.5% by mass of component (B), 1 to 5% by mass of component (C), and 0.001 to 5% by mass of component (D). The oral composition according to any one of [1] to [5].
[7]
The oral cavity composition according to any one of [1] to [6], which is a dentifrice composition.

According to the present invention, it is possible to provide an oral composition that improves the retention of potassium nitrate in the oral cavity, has excellent sustainability of the hypersensitivity suppressing effect, and has good foaming properties, and is suitable for suppressing hypersensitivity.

The present invention will be explained in more detail below. The oral composition of the present invention contains (A) potassium nitrate, (B) an α-olefin sulfonate, (C) a nonionic surfactant, and (D) a cationic polymeric substance.

(A) Potassium nitrate is a hypersensitivity suppressant that has a neurodepressant effect.
The blending amount of (A) potassium nitrate is preferably 1 to 10% (mass%, the same applies hereinafter) of the entire composition, and more preferably 3 to 8%. When the amount is 1% or more, the hypersensitivity suppressing effect is sufficiently expressed, and when it is 10% or less, the taste can be maintained by preventing the development of its own astringency.

(B) α-olefin sulfonate has the effect of ensuring foaming.
As component (B), sodium α-olefin sulfonic acid having 14 to 16 carbon atoms is selected in particular from the viewpoint of foaming property, retention of potassium ions in the oral cavity of component (A), and durability of the hypersensitivity suppressing effect. Alkali metal salts such as potassium and potassium can be used, preferably α-olefin sulfonates having 14 carbon atoms, especially sodium salts (common name: sodium tetradecene sulfonate). For these, commercially available products that can be used in oral compositions can be used, such as the trade name K-Liporan PJ-400CJ (manufactured by Lion Specialty Chemicals Co., Ltd.).

The blending amount of (B) α-olefin sulfonate is preferably 0.1 to 0.5%, more preferably 0.1 to 0.3% of the total composition. When the blending amount is 0.1% or more, sufficient foaming can be ensured. When the content is 0.5% or less, potassium ions can be sufficiently retained, the retention of component (A) in the oral cavity can be sufficiently improved, and the sustainability of the hypersensitivity suppressing effect can be improved. Moreover, especially when it is 0.3% or less, it is possible to sufficiently prevent the development of bitterness by itself and maintain a good taste.

In addition, in the present invention, anionic surfactants other than component (B), such as lauryl sulfate, acylamino acid salt, acyl taurine salt, etc., may be blended, but when these are blended, the effects of the present invention may be reduced. It is preferable to use the anionic surfactant other than component (B) within a range that does not interfere with the composition, and the amount of anionic surfactant other than component (B) is preferably 1% or less, particularly 0.5% or less, especially 0.3% or less of the total composition. It may be omitted and the content may be 0%.

(C) Nonionic surfactant, when used in combination with component (D), increases the retention of potassium ions, improves the retention of component (A) in the oral cavity, and improves the sustainability of the hypersensitivity suppressing effect. It has the effect of
(C) Nonionic surfactants include, for example, polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl ether, fatty acid glycerin ester, alkyl glycoside, sucrose fatty acid ester, alkylolamide, polyoxyethylene sorbitan monostearate, and polyoxyethylene sorbitan monostearate. Examples include ethylene polyoxypropylene glycol. Among these, polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl ether, fatty acid glycerin ester, and alkyl glycosides in which the alkyl group has 8 to 12 carbon atoms are preferable, particularly polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl ether, and fatty acid. Glycerin esters are preferred. As the fatty acid glycerin ester, a polyglycerin fatty acid ester can be used, and it may be a mono-, di-, or triester, or a mixture.
These may be used alone or in combination of two or more.
In addition, from the viewpoint of the retention of component (A) in the oral cavity and the sustainability of the hypersensitivity suppressing effect, the average number of moles of ethylene oxide added to polyoxyethylene hydrogenated castor oil is preferably 10 to 60 moles, more preferably 10 to 60 moles. The average number of moles of ethylene oxide added to the polyoxyethylene alkyl ether is preferably 5 to 30 moles, more preferably 5 to 10 moles, and the number of carbon atoms in the alkyl group is preferably 12 to 18. The fatty acid glycerin ester is preferably a polyglycerin fatty acid ester in which the fatty acid has 12 to 18 carbon atoms, and specifically, lauric acid decaglycerin monoester and the like can be used.
(C) A commercially available product can be used as the nonionic surfactant.

The amount of nonionic surfactant (C) blended is preferably 1 to 5%, more preferably 1.3 to 4.5% of the total composition. When the blending amount is 1% or more, potassium ions are sufficiently retained, the retention of component (A) in the oral cavity is sufficiently improved, and the durability of the hypersensitivity suppressing effect is more excellent. When it is 5% or less, sufficient foaming can be ensured.

In the present invention, (B)/(C), which indicates the ratio of the amounts of components (B) and (C), is 0.02 to 0.2 as a mass ratio, preferably 0.04 to 0.15. It is. If (B)/(C) exceeds 0.2, the retention of potassium ions will not be improved even if component (D) is blended, and the retention of component (A) in the oral cavity will be poor, resulting in an effect of suppressing hypersensitivity. The sustainability is also poor. If it is less than 0.02, foaming will be poor even if component (B) is blended.

(D) When used in combination with component (C), the cationic polymer substance increases the retention of potassium ions, improves the retention of component (A) in the oral cavity, and particularly improves the sustainability of the hypersensitivity suppressing effect. It has an improving effect. Although the details of the mechanism of action are not clear, component (D) has low reactivity with potassium ions and high adsorption to the tooth surface, which contributes to preventing the outflow of potassium ions from the dentinal tubules. It is assumed that

The cationic polymeric substance of component (D) includes a cationized cellulose polymer, a homopolymer of dimethyldiallylammonium, a copolymer of dimethyldiallylammonium chloride and a polymerizable monomer having an ethylenically unsaturated hydrocarbon group, and a cationized polymer. Polyvinylpyrrolidone, cationic polyamide, cationic polymethacrylate, cationic polyacrylamide, copolymer of cationic methacrylate and acrylamide, copolymer of cationic methacrylate and methacrylate, polyethyleneimide, cationic starch, cationic amylose, cationic guar gum, cationic Examples include cationized roasted bean gum, cationized agar, chitin, chitosan, and modified products thereof, and these may be used alone or in combination of two or more. Among these, from the viewpoint of the retention of component (A) in the oral cavity and the sustainability of the hypersensitivity suppressing effect, cationic cellulose-based polymers, dimethyldiallylammonium homopolymers, dimethyldiallylammonium chloride and ethylenically unsaturated hydrocarbon groups are preferred. Copolymers with polymerizable monomers having the following are preferred, cationized polymethacrylates are preferred, and cationized cellulose-based polymers are more preferred, and hydroxyethyl cellulose dimethyldiallylammonium chloride, in which dimethyldiallylammonium is added to a cellulose derivative as a cationic group, is particularly preferred. .
(D) As the cationic polymer substance, a commercially available product can be used. For example, hydroxyethyl cellulose dimethyl diallylammonium chloride can be used under the trade name Cellcoat L-200 (manufactured by Akzo Nobel, Inc.).

(D) The amount of the cationic polymer substance blended is preferably 0.001 to 5%, more preferably 0.01 to 2% of the total composition. When the blending amount is 0.001% or more, the retention of potassium ions increases, the retention of component (A) in the oral cavity is sufficiently improved, and the durability of the hypersensitivity suppressing effect is more excellent. When the content is 5% or less, the appearance of the preparation and the feeling of use with good taste and odor can be sufficiently maintained. When the content is 2% or less, a preparation with a sufficiently smooth surface and a good appearance can be obtained, especially when used as a toothpaste or gel-like dentifrice.

The oral composition of the present invention can be used as a dentifrice, a mouthwash, a liniment, a patch, etc., and the form is not particularly limited, and can be prepared in liquid, liquid, paste, etc. It is. Particularly preferred are dentifrice compositions or mouthwash compositions, especially dentifrice compositions. The dentifrice composition is preferably prepared into a toothpaste, a liquid dentifrice, a liquid dentifrice, a moisturized dentifrice, etc., particularly a toothpaste.
In addition to the above ingredients, other known ingredients may be added as necessary depending on the dosage form, form, use, etc. Other optional ingredients other than the above ingredients may be added within a range that does not impede the effects of the present invention. It can be mixed as appropriate. Specifically, dentifrice compositions such as toothpastes contain abrasives, binders, thickeners, cationic surfactants and amphoteric surfactants as surfactants, and if necessary, sweeteners and preservatives. , pigments, fragrances, various active ingredients, etc. may be added.

Abrasives include silica-based abrasives such as crystalline silica, amorphous silica, silica gel, and aluminosilicate, zeolite, calcium hydrogen phosphate anhydrate, tertiary calcium phosphate, quaternary calcium phosphate, and calcium hydrogen phosphate dihydrate. , calcium pyrophosphate, calcium carbonate, aluminum hydroxide, alumina, magnesium carbonate, tertiary magnesium phosphate, zirconium silicate, hydroxyapatite, and synthetic resin abrasives. The amount of abrasive is usually 5 to 70%, particularly 10 to 50% of the total composition.

The binder may contain an organic binder or an inorganic binder other than component (D). Specifically, examples of the organic binder include sodium carboxymethyl cellulose, alginate, xanthan gum, carrageenan, etc., and examples of the inorganic binder include gelling silica, gelling aluminum silica, and the like. The amount of these organic binders is preferably 0 to 5% of the total composition, and the amount of inorganic binders is preferably 0 to 10% of the total composition.

Examples of thickeners include sugar alcohols such as sorbitol, xylitol, and erythritol, and polyhydric alcohols such as propylene glycol, butylene glycol, glycerin, and polyethylene glycol. The amount of the thickening agent is usually 0 to 70%, particularly 3 to 50% of the total composition.

Examples of the surfactant include cationic surfactants such as alkylammonium and alkylbenzylammonium salts, and amphoteric surfactants such as betaine acetate, betaine, imidazoline, and imidazolium betaine. The amount of the cationic surfactant and the amphoteric surfactant is preferably 0 to 3% of the total composition.

Examples of sweeteners include sodium saccharin.
Examples of preservatives include benzoates such as sodium benzoate, and paraoxybenzoic acid esters such as methylparaben, ethylparaben, and butylparaben.
Examples of pigments include food pigments such as brilliant blue and tartrazine, and pigments such as titanium oxide.

Fragrances include peppermint oil, spearmint oil, anise oil, eucalyptus oil, wintergreen oil, cassia oil, clove oil, thyme oil, sage oil, lemon oil, orange oil, peppermint oil, cardamom oil, coriander oil, mandarin oil, lime. Oil, lavender oil, rosemary oil, laurel oil, chamomile oil, caraway oil, marjoram oil, bay oil, lemongrass oil, origanum oil, pine needle oil, neroli oil, rose oil, jasmine oil, grapefruit oil, sweetie oil Natural fragrances such as , yuzu oil, iris concrete, absolute peppermint, absolute rose, orange flower, etc., and processing of these natural fragrances (front distillation cut, rear distillation cut, fractional distillation, liquid extraction, essence production, powder fragrance production) etc.), and l-menthol, carvone, anethole, cineole, methyl salicylate, cinnamic aldehyde, eugenol, 3-l-menthoxypropane-1,2-diol, thymol, linalool, linaryl acetate, limonene, Menthone, menthyl acetate, N-substituted-paramenthane-3-carboxamide, pinene, octylaldehyde, citral, pulegone, carbyl acetate, anisaldehyde, ethyl acetate, ethyl butyrate, allylcyclohexanepropionate, methyl anthranilate, ethyl Individual fragrances such as methylphenylglycidate, vanillin, undecalactone, hexanal, butanol, isoamyl alcohol, hexenol, dimethyl sulfide, cyclotene, furfural, trimethylpyrazine, ethyl lactate, and ethylthioacetate, as well as strawberry flavor, apple flavor, and banana. It is possible to use a combination of known flavor materials used in oral compositions, such as blended flavors such as pineapple flavor, grape flavor, mango flavor, butter flavor, milk flavor, mixed fruit flavor, and tropical fruit flavor. Further, the amount of the fragrance material to be blended is not particularly limited, but it is preferable that the above-mentioned fragrance material is used in the composition in an amount of 0.000001 to 1%. It is preferable to use 0.1 to 2% of the fragrance material in the composition for flavoring using the above fragrance material.

In addition to component (A), active ingredients include bactericidal or antibacterial agents such as chlorhexidine, triclosan, isopropylmethylphenol, cetylpyridinium chloride, benzethonium chloride, benzalkonium chloride, zinc gluconate, zinc citrate, and ethane hydroxydi Tartar prevention agents such as phosphonates, tranexamic acid, glycyrrhizic acid and its salts, anti-inflammatory agents such as allantoin chlorhydroxyaluminum, enzyme agents such as dextranase, mutanase, lysozyme chloride, vitamins such as ascorbic acid, tocopherol acetate, etc. , astringents such as sodium chloride, hypersensitivity suppressants other than component (A) such as aluminum lactate and strontium chloride, and fluorine-containing compounds such as sodium fluoride, sodium monofluorophosphate, and stannous fluoride. These can be used within a pharmaceutically acceptable range without interfering with the effects of the present invention.

EXAMPLES Hereinafter, the present invention will be specifically explained with reference to Examples and Comparative Examples, but the present invention is not limited to the following Examples. In addition, in the following examples, % indicates mass % unless otherwise specified.

[Examples, comparative examples]
Dentifrice compositions (dentifrices) having the compositions shown in Tables 1 to 3 were prepared by a conventional method and evaluated by the following method. The results are also listed in Tables 1 to 3.

(1) Method for evaluating the retention of potassium nitrate in the oral cavity A dentifrice composition diluted 4 times with purified water is applied to a hydroxyapatite (HA) disk (diameter 7 mm, thickness 3.5 mm, manufactured by PENTAX) for 3 minutes. and immediately washed with purified water. After drying the HA disk, the top surface of the HA disk was deashed with 80 μL of 0.1N HCl for 2 minutes, potassium ions were extracted, and the amount of potassium ions contained in the solution was measured using an ion meter (Orion 1115000 4-Star: Thermometer). (manufactured by Fisher Scientific) and evaluated based on the following criteria (N=6).
Evaluation criteria ◎: Potassium ion amount is 2.0 ppm or more ○: Potassium ion amount is 1.5 ppm or more and less than 2.0 ppm ×: Potassium ion amount is less than 1.5 ppm

(2) Evaluation method for sustainability of hypersensitivity suppressing effect Evaluation was carried out through a sensory test using 10 panelists as subjects whose teeth were sensitive to cold water in their mouths. After taking 1 cm of the dentifrice composition on the fingertip and directly imprinting it on the affected teeth, the subjects brushed their teeth in the same way as usual for 3 minutes. One hour after brushing the teeth, the degree to which the teeth stung when cold water was sipped in the mouth was evaluated according to the rating criteria shown below. The average score of 10 people was calculated and evaluated according to the evaluation criteria shown below.
Scoring Criteria: 5 points: Even if you put cold water in your mouth, your teeth won't stain at all (no discomfort).
4 points: Even if you take cold water in your mouth, your teeth won't get stained. 3 points: Even if you take cold water in your mouth, your teeth won't get stained. 2 points: If you take cold water in your mouth, your teeth will get stained. 1 point: Cold water If you put it in your mouth, your teeth will become extremely sensitive. Evaluation criteria: ◎: Average score is 4.0 points or more and 5.0 points or less. ○: Average score is 3.0 points or more and less than 4.0 points. △: Average score is 2.0 points or more. 0 points or more and less than 3.0 points ×: Average score is less than 2.0 points

(3) Evaluation method of foaming property in the oral cavity (foaming speed and foaming amount during tooth brushing) Evaluation was carried out by a sensory test using 10 expert panelists as subjects. The dentifrice composition was extruded 1 cm onto a toothbrush, the teeth were brushed for 3 minutes in the same manner as usual, and the foamability in the oral cavity (foaming speed and amount of foaming during tooth brushing) was evaluated based on the scoring criteria shown below. The average score of 10 people was calculated and evaluated according to the evaluation criteria shown below.
Scoring Criteria 4 points: The foaming speed is very fast and the amount of foaming is large. 3 points: The foaming speed is fast, but the amount of foaming is somewhat small. 2 points: The foaming speed is slow. 1 point: There is almost no foaming.
Evaluation criteria ◎: 3.5 points or more and 4.0 points or less ○: 3.0 points or more and less than 3.5 points △: 2.0 points or more and less than 3.0 points ×: Less than 2.0 points

Details of the raw materials used are shown below.
(A) Potassium nitrate Product name: Potassium nitrate (manufactured by Otsuka Chemical Co., Ltd.)
(B) Sodium tetradecene sulfonate Product name: K Liporan PJ-400CJ (manufactured by Lion Specialty Chemicals Co., Ltd.)
(C) Polyoxyethylene (20) Hydrogenated castor oil Product name: HCO-20 (average number of added moles of ethylene oxide 20) (manufactured by Nikko Chemicals Co., Ltd.)
(C) Polyoxyethylene (5) Stearyl ether Product name: POE stearyl ether (polyoxyethylene stearyl ether, average number of added moles of ethylene oxide 5) (manufactured by Lion Chemical Co., Ltd.)
(C) Fatty acid glycerin ester Product name: SY Glister ML-750 (lauric acid decaglycerin monoester) (manufactured by Sakamoto Pharmaceutical Co., Ltd.)
(C) Alkyl glycoside Product name: Alkyl glycoside (alkyl group has 8 carbon atoms) (manufactured by Lion Corporation)
(D) Hydroxyethyl cellulose dimethyl diallylammonium chloride Product name: Cellcoat L-200 (manufactured by Akzo Nobel Co., Ltd.)

Claims (9)

(A) 1 to 10% by mass of potassium nitrate,
(B) 0.1 to 0.5% by mass of α-olefin sulfonate,
(C) 1 to 5% by mass of a nonionic surfactant, and (D) 0.001 to 5% by mass of a cationic polymer substance.
An oral cavity composition characterized in that (B)/(C), which represents the quantitative ratio of components (B) and (C), is 0.02 to 0.2 as a mass ratio. The oral composition according to claim 1, wherein the α-olefin sulfonate (B) has 14 to 16 carbon atoms. The oral composition according to claim 1 or 2, wherein the nonionic surfactant (C) is one or more selected from polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl ether, fatty acid glycerin ester, and alkyl glycoside. thing. (D) The cationic polymeric substance is made of a cationic cellulose polymer, a homopolymer of dimethyldiallylammonium, a copolymer of dimethyldiallylammonium chloride and a polymerizable monomer having an ethylenically unsaturated hydrocarbon group, and a cationized polymethacrylate. The oral composition according to any one of claims 1 to 3, which comprises one or more selected types. The oral composition according to claim 4, wherein the cationic polymeric substance (D) is hydroxyethylcellulose dimethyldiallylammonium chloride. The oral composition according to any one of claims 1 to 5 , which contains 1.3 to 4.5 % by mass of component (C) and 0.01 to 2 % by mass of component ( D). The oral composition according to any one of claims 1 to 6, wherein (B)/(C), which represents the quantitative ratio of components (B) and (C), is 0.04 to 0.15 as a mass ratio.. The oral composition according to any one of claims 1 to 7 , which is a dentifrice composition. The oral composition according to any one of claims 1 to 8, which is used for suppressing hypersensitivity .