JPWO2017191680A1 - 発熱具 - Google Patents
発熱具 Download PDFInfo
- Publication number
- JPWO2017191680A1 JPWO2017191680A1 JP2018515381A JP2018515381A JPWO2017191680A1 JP WO2017191680 A1 JPWO2017191680 A1 JP WO2017191680A1 JP 2018515381 A JP2018515381 A JP 2018515381A JP 2018515381 A JP2018515381 A JP 2018515381A JP WO2017191680 A1 JPWO2017191680 A1 JP WO2017191680A1
- Authority
- JP
- Japan
- Prior art keywords
- heating tool
- packaging material
- adhesive layer
- container
- release sheet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000010438 heat treatment Methods 0.000 title claims abstract description 127
- 239000010410 layer Substances 0.000 claims abstract description 137
- 239000012790 adhesive layer Substances 0.000 claims abstract description 96
- 239000005022 packaging material Substances 0.000 claims abstract description 89
- 230000004888 barrier function Effects 0.000 claims abstract description 57
- 239000007789 gas Substances 0.000 claims description 47
- 230000002093 peripheral effect Effects 0.000 claims description 34
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 32
- 239000001301 oxygen Substances 0.000 claims description 32
- 229910052760 oxygen Inorganic materials 0.000 claims description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 27
- 230000035699 permeability Effects 0.000 claims description 26
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 18
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 18
- 229940041616 menthol Drugs 0.000 claims description 18
- 239000000853 adhesive Substances 0.000 claims description 16
- 230000001070 adhesive effect Effects 0.000 claims description 16
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 claims description 8
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 claims description 8
- VLDFMKOUUQYFGF-UHFFFAOYSA-N 4-(butoxymethyl)-2-methoxyphenol Chemical compound CCCCOCC1=CC=C(O)C(OC)=C1 VLDFMKOUUQYFGF-UHFFFAOYSA-N 0.000 claims description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 6
- KVYGGMBOZFWZBQ-UHFFFAOYSA-N benzyl nicotinate Chemical compound C=1C=CN=CC=1C(=O)OCC1=CC=CC=C1 KVYGGMBOZFWZBQ-UHFFFAOYSA-N 0.000 claims description 6
- YKPUWZUDDOIDPM-SOFGYWHQSA-N capsaicin Chemical compound COC1=CC(CNC(=O)CCCC\C=C\C(C)C)=CC=C1O YKPUWZUDDOIDPM-SOFGYWHQSA-N 0.000 claims description 6
- 229940002508 ginger extract Drugs 0.000 claims description 6
- 235000020708 ginger extract Nutrition 0.000 claims description 6
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims description 6
- 230000000149 penetrating effect Effects 0.000 claims description 6
- 235000019477 peppermint oil Nutrition 0.000 claims description 6
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 claims description 6
- 229940078465 vanillyl butyl ether Drugs 0.000 claims description 6
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims description 5
- 239000002253 acid Substances 0.000 claims description 5
- 241000723346 Cinnamomum camphora Species 0.000 claims description 4
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 claims description 4
- 229960001948 caffeine Drugs 0.000 claims description 4
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 claims description 4
- 229930008380 camphor Natural products 0.000 claims description 4
- 229960000846 camphor Drugs 0.000 claims description 4
- 229960001047 methyl salicylate Drugs 0.000 claims description 4
- BPIUIOXAFBGMNB-UHFFFAOYSA-N 1-hexoxyhexane Chemical compound CCCCCCOCCCCCC BPIUIOXAFBGMNB-UHFFFAOYSA-N 0.000 claims description 3
- 239000005844 Thymol Substances 0.000 claims description 3
- MSCCTZZBYHQMQJ-AZAGJHQNSA-N Tocopheryl nicotinate Chemical compound C([C@@](OC1=C(C)C=2C)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)CC1=C(C)C=2OC(=O)C1=CC=CN=C1 MSCCTZZBYHQMQJ-AZAGJHQNSA-N 0.000 claims description 3
- 229950004580 benzyl nicotinate Drugs 0.000 claims description 3
- 229960002504 capsaicin Drugs 0.000 claims description 3
- 235000017663 capsaicin Nutrition 0.000 claims description 3
- POLCUAVZOMRGSN-UHFFFAOYSA-N dipropyl ether Chemical compound CCCOCCC POLCUAVZOMRGSN-UHFFFAOYSA-N 0.000 claims description 3
- NLDDIKRKFXEWBK-AWEZNQCLSA-N gingerol Chemical compound CCCCC[C@H](O)CC(=O)CCC1=CC=C(O)C(OC)=C1 NLDDIKRKFXEWBK-AWEZNQCLSA-N 0.000 claims description 3
- JZLXEKNVCWMYHI-UHFFFAOYSA-N gingerol Natural products CCCCC(O)CC(=O)CCC1=CC=C(O)C(OC)=C1 JZLXEKNVCWMYHI-UHFFFAOYSA-N 0.000 claims description 3
- 235000002780 gingerol Nutrition 0.000 claims description 3
- 229940077082 red pepper extract Drugs 0.000 claims description 3
- 235000002020 sage Nutrition 0.000 claims description 3
- 229960000790 thymol Drugs 0.000 claims description 3
- 229950009883 tocopheryl nicotinate Drugs 0.000 claims description 3
- TZZAKSLHHIJRLL-UHFFFAOYSA-N 4-hydroxy-3-methoxybenzamide Chemical compound COC1=CC(C(N)=O)=CC=C1O TZZAKSLHHIJRLL-UHFFFAOYSA-N 0.000 claims description 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 2
- 125000001400 nonyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 2
- 229930184148 Spiranthol Natural products 0.000 claims 1
- 238000003860 storage Methods 0.000 abstract description 30
- 230000009471 action Effects 0.000 abstract description 10
- 238000001179 sorption measurement Methods 0.000 abstract description 4
- 229920005989 resin Polymers 0.000 description 64
- 239000011347 resin Substances 0.000 description 64
- 239000000463 material Substances 0.000 description 59
- 239000000203 mixture Substances 0.000 description 52
- 229910052751 metal Inorganic materials 0.000 description 39
- 239000002184 metal Substances 0.000 description 39
- 239000002585 base Substances 0.000 description 35
- -1 pulp Substances 0.000 description 31
- 239000000835 fiber Substances 0.000 description 28
- 239000011888 foil Substances 0.000 description 25
- 239000003795 chemical substances by application Substances 0.000 description 18
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 16
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 16
- 238000007254 oxidation reaction Methods 0.000 description 16
- 238000000034 method Methods 0.000 description 15
- 230000003647 oxidation Effects 0.000 description 15
- 238000007740 vapor deposition Methods 0.000 description 15
- 229920000139 polyethylene terephthalate Polymers 0.000 description 12
- 239000005020 polyethylene terephthalate Substances 0.000 description 12
- 230000000052 comparative effect Effects 0.000 description 11
- 230000020169 heat generation Effects 0.000 description 11
- 238000003466 welding Methods 0.000 description 11
- 230000000694 effects Effects 0.000 description 10
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 9
- 239000000284 extract Substances 0.000 description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- 239000004698 Polyethylene Substances 0.000 description 8
- 229910052782 aluminium Inorganic materials 0.000 description 8
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 8
- 239000003205 fragrance Substances 0.000 description 8
- 238000003475 lamination Methods 0.000 description 8
- 239000004743 Polypropylene Substances 0.000 description 7
- 230000005540 biological transmission Effects 0.000 description 7
- 229920000573 polyethylene Polymers 0.000 description 7
- 150000003839 salts Chemical class 0.000 description 7
- 229920005992 thermoplastic resin Polymers 0.000 description 7
- 239000004677 Nylon Substances 0.000 description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 6
- 239000002998 adhesive polymer Substances 0.000 description 6
- 239000003610 charcoal Substances 0.000 description 6
- 230000035597 cooling sensation Effects 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 239000004745 nonwoven fabric Substances 0.000 description 6
- 229920001778 nylon Polymers 0.000 description 6
- 239000002245 particle Substances 0.000 description 6
- 229920001155 polypropylene Polymers 0.000 description 6
- 229920001296 polysiloxane Polymers 0.000 description 6
- 238000007873 sieving Methods 0.000 description 6
- 239000004793 Polystyrene Substances 0.000 description 5
- 238000000576 coating method Methods 0.000 description 5
- 239000000470 constituent Substances 0.000 description 5
- 229920001971 elastomer Polymers 0.000 description 5
- 229920002223 polystyrene Polymers 0.000 description 5
- 239000011148 porous material Substances 0.000 description 5
- 238000007789 sealing Methods 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 244000025254 Cannabis sativa Species 0.000 description 4
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 238000009820 dry lamination Methods 0.000 description 4
- 230000014759 maintenance of location Effects 0.000 description 4
- 230000000144 pharmacologic effect Effects 0.000 description 4
- 229920005862 polyol Polymers 0.000 description 4
- 150000003077 polyols Chemical class 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 239000002356 single layer Substances 0.000 description 4
- 238000010792 warming Methods 0.000 description 4
- 229920000742 Cotton Polymers 0.000 description 3
- 229920000219 Ethylene vinyl alcohol Polymers 0.000 description 3
- 229920002125 Sokalan® Polymers 0.000 description 3
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- 239000002537 cosmetic Substances 0.000 description 3
- 238000004049 embossing Methods 0.000 description 3
- 230000002708 enhancing effect Effects 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 238000001125 extrusion Methods 0.000 description 3
- 230000001965 increasing effect Effects 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 229910052742 iron Inorganic materials 0.000 description 3
- 238000005304 joining Methods 0.000 description 3
- 238000010030 laminating Methods 0.000 description 3
- 150000002739 metals Chemical class 0.000 description 3
- 239000002304 perfume Substances 0.000 description 3
- 239000004584 polyacrylic acid Substances 0.000 description 3
- 229920002239 polyacrylonitrile Polymers 0.000 description 3
- 239000004800 polyvinyl chloride Substances 0.000 description 3
- 229920000915 polyvinyl chloride Polymers 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 238000010998 test method Methods 0.000 description 3
- 239000010455 vermiculite Substances 0.000 description 3
- 229910052902 vermiculite Inorganic materials 0.000 description 3
- 235000019354 vermiculite Nutrition 0.000 description 3
- 229910052725 zinc Inorganic materials 0.000 description 3
- 239000011701 zinc Substances 0.000 description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- POEDHWVTLBLWDA-UHFFFAOYSA-N 1-butylindole-2,3-dione Chemical compound C1=CC=C2N(CCCC)C(=O)C(=O)C2=C1 POEDHWVTLBLWDA-UHFFFAOYSA-N 0.000 description 2
- LVYLCBNXHHHPSB-UHFFFAOYSA-N 2-hydroxyethyl salicylate Chemical compound OCCOC(=O)C1=CC=CC=C1O LVYLCBNXHHHPSB-UHFFFAOYSA-N 0.000 description 2
- KOCVACNWDMSLBM-UHFFFAOYSA-N 4-(Ethoxymethyl)-2-methoxyphenol Chemical compound CCOCC1=CC=C(O)C(OC)=C1 KOCVACNWDMSLBM-UHFFFAOYSA-N 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 2
- 241000157282 Aesculus Species 0.000 description 2
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 2
- 235000017491 Bambusa tulda Nutrition 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 235000012766 Cannabis sativa ssp. sativa var. sativa Nutrition 0.000 description 2
- 235000012765 Cannabis sativa ssp. sativa var. spontanea Nutrition 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 2
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 2
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 description 2
- 244000082204 Phyllostachys viridis Species 0.000 description 2
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 229920000297 Rayon Polymers 0.000 description 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 2
- 229920002978 Vinylon Polymers 0.000 description 2
- 239000011425 bamboo Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 235000009120 camo Nutrition 0.000 description 2
- 235000005607 chanvre indien Nutrition 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000010227 cup method (microbiological evaluation) Methods 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 239000005038 ethylene vinyl acetate Substances 0.000 description 2
- 235000013312 flour Nutrition 0.000 description 2
- 210000000245 forearm Anatomy 0.000 description 2
- 239000011487 hemp Substances 0.000 description 2
- 235000010181 horse chestnut Nutrition 0.000 description 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 229910052749 magnesium Inorganic materials 0.000 description 2
- 239000011777 magnesium Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 229930003658 monoterpene Natural products 0.000 description 2
- 150000002773 monoterpene derivatives Chemical class 0.000 description 2
- 229910052759 nickel Inorganic materials 0.000 description 2
- RGOVYLWUIBMPGK-UHFFFAOYSA-N nonivamide Chemical compound CCCCCCCCC(=O)NCC1=CC=C(O)C(OC)=C1 RGOVYLWUIBMPGK-UHFFFAOYSA-N 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 235000019198 oils Nutrition 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 2
- 229920001707 polybutylene terephthalate Polymers 0.000 description 2
- 239000004417 polycarbonate Substances 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000002964 rayon Substances 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 229910052709 silver Inorganic materials 0.000 description 2
- 239000004332 silver Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- 229920002994 synthetic fiber Polymers 0.000 description 2
- 239000012209 synthetic fiber Substances 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 239000002023 wood Substances 0.000 description 2
- 239000002759 woven fabric Substances 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- VZSRBBMJRBPUNF-UHFFFAOYSA-N 2-(2,3-dihydro-1H-inden-2-ylamino)-N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]pyrimidine-5-carboxamide Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C(=O)NCCC(N1CC2=C(CC1)NN=N2)=O VZSRBBMJRBPUNF-UHFFFAOYSA-N 0.000 description 1
- OEPOKWHJYJXUGD-UHFFFAOYSA-N 2-(3-phenylmethoxyphenyl)-1,3-thiazole-4-carbaldehyde Chemical compound O=CC1=CSC(C=2C=C(OCC=3C=CC=CC=3)C=CC=2)=N1 OEPOKWHJYJXUGD-UHFFFAOYSA-N 0.000 description 1
- GOXQRTZXKQZDDN-UHFFFAOYSA-N 2-Ethylhexyl acrylate Chemical compound CCCCC(CC)COC(=O)C=C GOXQRTZXKQZDDN-UHFFFAOYSA-N 0.000 description 1
- AJBZENLMTKDAEK-UHFFFAOYSA-N 3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-4,9-diol Chemical compound CC12CCC(O)C(C)(C)C1CCC(C1(C)CC3O)(C)C2CCC1C1C3(C)CCC1C(=C)C AJBZENLMTKDAEK-UHFFFAOYSA-N 0.000 description 1
- UPMLOUAZCHDJJD-UHFFFAOYSA-N 4,4'-Diphenylmethane Diisocyanate Chemical compound C1=CC(N=C=O)=CC=C1CC1=CC=C(N=C=O)C=C1 UPMLOUAZCHDJJD-UHFFFAOYSA-N 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 description 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- 235000003880 Calendula Nutrition 0.000 description 1
- 240000001432 Calendula officinalis Species 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- 229910001018 Cast iron Inorganic materials 0.000 description 1
- 240000003538 Chamaemelum nobile Species 0.000 description 1
- 235000007866 Chamaemelum nobile Nutrition 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- 244000060011 Cocos nucifera Species 0.000 description 1
- 235000013162 Cocos nucifera Nutrition 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 241000195955 Equisetum hyemale Species 0.000 description 1
- JIGUQPWFLRLWPJ-UHFFFAOYSA-N Ethyl acrylate Chemical compound CCOC(=O)C=C JIGUQPWFLRLWPJ-UHFFFAOYSA-N 0.000 description 1
- 244000119830 Ferocactus wislizenii Species 0.000 description 1
- 235000017187 Ferocactus wislizenii Nutrition 0.000 description 1
- 235000011201 Ginkgo Nutrition 0.000 description 1
- 235000008100 Ginkgo biloba Nutrition 0.000 description 1
- 244000194101 Ginkgo biloba Species 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- 241000208690 Hamamelis Species 0.000 description 1
- 239000005057 Hexamethylene diisocyanate Substances 0.000 description 1
- 108010003272 Hyaluronate lyase Proteins 0.000 description 1
- 102000001974 Hyaluronidases Human genes 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 241000546188 Hypericum Species 0.000 description 1
- 235000017309 Hypericum perforatum Nutrition 0.000 description 1
- 208000029422 Hypernatremia Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 239000005909 Kieselgur Substances 0.000 description 1
- 235000007232 Matricaria chamomilla Nutrition 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 description 1
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical class OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 1
- 235000010676 Ocimum basilicum Nutrition 0.000 description 1
- 240000007926 Ocimum gratissimum Species 0.000 description 1
- 239000006002 Pepper Substances 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 235000016761 Piper aduncum Nutrition 0.000 description 1
- 240000003889 Piper guineense Species 0.000 description 1
- 235000017804 Piper guineense Nutrition 0.000 description 1
- 235000008184 Piper nigrum Nutrition 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 229920000805 Polyaspartic acid Polymers 0.000 description 1
- 108010020346 Polyglutamic Acid Proteins 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 229910021536 Zeolite Inorganic materials 0.000 description 1
- 244000273928 Zingiber officinale Species 0.000 description 1
- 235000006886 Zingiber officinale Nutrition 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 229940022663 acetate Drugs 0.000 description 1
- 239000006230 acetylene black Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000003522 acrylic cement Substances 0.000 description 1
- 238000007259 addition reaction Methods 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 150000001340 alkali metals Chemical class 0.000 description 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 1
- 150000001342 alkaline earth metals Chemical class 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- FQPFAHBPWDRTLU-UHFFFAOYSA-N aminophylline Chemical compound NCCN.O=C1N(C)C(=O)N(C)C2=C1NC=N2.O=C1N(C)C(=O)N(C)C2=C1NC=N2 FQPFAHBPWDRTLU-UHFFFAOYSA-N 0.000 description 1
- 229960003556 aminophylline Drugs 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 229930014669 anthocyanidin Natural products 0.000 description 1
- 150000001453 anthocyanidins Chemical class 0.000 description 1
- 235000008758 anthocyanidins Nutrition 0.000 description 1
- 239000004410 anthocyanin Substances 0.000 description 1
- 235000010208 anthocyanin Nutrition 0.000 description 1
- 229930002877 anthocyanin Natural products 0.000 description 1
- 150000004636 anthocyanins Chemical class 0.000 description 1
- 210000000617 arm Anatomy 0.000 description 1
- 239000012298 atmosphere Substances 0.000 description 1
- 210000000467 autonomic pathway Anatomy 0.000 description 1
- 239000000440 bentonite Substances 0.000 description 1
- 229910000278 bentonite Inorganic materials 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- QRZAKQDHEVVFRX-UHFFFAOYSA-N biphenyl-4-ylacetic acid Chemical compound C1=CC(CC(=O)O)=CC=C1C1=CC=CC=C1 QRZAKQDHEVVFRX-UHFFFAOYSA-N 0.000 description 1
- 239000002802 bituminous coal Substances 0.000 description 1
- 210000001217 buttock Anatomy 0.000 description 1
- CQEYYJKEWSMYFG-UHFFFAOYSA-N butyl acrylate Chemical compound CCCCOC(=O)C=C CQEYYJKEWSMYFG-UHFFFAOYSA-N 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 239000000378 calcium silicate Substances 0.000 description 1
- 229910052918 calcium silicate Inorganic materials 0.000 description 1
- 235000012241 calcium silicate Nutrition 0.000 description 1
- CNYFJCCVJNARLE-UHFFFAOYSA-L calcium;2-sulfanylacetic acid;2-sulfidoacetate Chemical compound [Ca+2].[O-]C(=O)CS.[O-]C(=O)CS CNYFJCCVJNARLE-UHFFFAOYSA-L 0.000 description 1
- OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 description 1
- 239000006229 carbon black Substances 0.000 description 1
- 239000003575 carbonaceous material Substances 0.000 description 1
- 229940008396 carrot extract Drugs 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 235000010980 cellulose Nutrition 0.000 description 1
- 229940106189 ceramide Drugs 0.000 description 1
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 description 1
- 238000005229 chemical vapour deposition Methods 0.000 description 1
- 150000001805 chlorine compounds Chemical class 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000011651 chromium Substances 0.000 description 1
- 239000003245 coal Substances 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 239000002826 coolant Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 239000008406 cosmetic ingredient Substances 0.000 description 1
- 150000004292 cyclic ethers Chemical group 0.000 description 1
- 150000003997 cyclic ketones Chemical group 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- SHFGJEQAOUMGJM-UHFFFAOYSA-N dialuminum dipotassium disodium dioxosilane iron(3+) oxocalcium oxomagnesium oxygen(2-) Chemical compound [O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[Na+].[Na+].[Al+3].[Al+3].[K+].[K+].[Fe+3].[Fe+3].O=[Mg].O=[Ca].O=[Si]=O SHFGJEQAOUMGJM-UHFFFAOYSA-N 0.000 description 1
- 229960001259 diclofenac Drugs 0.000 description 1
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 description 1
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 229940011399 escin Drugs 0.000 description 1
- 229930186222 escin Natural products 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 229960000192 felbinac Drugs 0.000 description 1
- 229960002390 flurbiprofen Drugs 0.000 description 1
- SYTBZMRGLBWNTM-UHFFFAOYSA-N flurbiprofen Chemical compound FC1=CC(C(C(O)=O)C)=CC=C1C1=CC=CC=C1 SYTBZMRGLBWNTM-UHFFFAOYSA-N 0.000 description 1
- FODTZLFLDFKIQH-FSVGXZBPSA-N gamma-Oryzanol (TN) Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)O[C@@H]2C([C@@H]3CC[C@H]4[C@]5(C)CC[C@@H]([C@@]5(C)CC[C@@]54C[C@@]53CC2)[C@H](C)CCC=C(C)C)(C)C)=C1 FODTZLFLDFKIQH-FSVGXZBPSA-N 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 238000004817 gas chromatography Methods 0.000 description 1
- 235000008397 ginger Nutrition 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 229960002389 glycol salicylate Drugs 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229940065115 grapefruit extract Drugs 0.000 description 1
- 239000010439 graphite Substances 0.000 description 1
- 229910002804 graphite Inorganic materials 0.000 description 1
- 238000005338 heat storage Methods 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- RRAMGCGOFNQTLD-UHFFFAOYSA-N hexamethylene diisocyanate Chemical compound O=C=NCCCCCCN=C=O RRAMGCGOFNQTLD-UHFFFAOYSA-N 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 229960002773 hyaluronidase Drugs 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-M hydrogensulfate Chemical compound OS([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-M 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 229960000905 indomethacin Drugs 0.000 description 1
- 239000008235 industrial water Substances 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 229910001506 inorganic fluoride Inorganic materials 0.000 description 1
- 229910052809 inorganic oxide Inorganic materials 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- FBAFATDZDUQKNH-UHFFFAOYSA-M iron chloride Chemical compound [Cl-].[Fe] FBAFATDZDUQKNH-UHFFFAOYSA-M 0.000 description 1
- 239000000453 juniperus communis l. leaf oil Substances 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- DKYWVDODHFEZIM-UHFFFAOYSA-N ketoprofen Chemical compound OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-UHFFFAOYSA-N 0.000 description 1
- 229960000991 ketoprofen Drugs 0.000 description 1
- 210000002414 leg Anatomy 0.000 description 1
- 239000003077 lignite Substances 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- ORUIBWPALBXDOA-UHFFFAOYSA-L magnesium fluoride Chemical compound [F-].[F-].[Mg+2] ORUIBWPALBXDOA-UHFFFAOYSA-L 0.000 description 1
- 229910001635 magnesium fluoride Inorganic materials 0.000 description 1
- 239000000391 magnesium silicate Substances 0.000 description 1
- 229910052919 magnesium silicate Inorganic materials 0.000 description 1
- 235000019792 magnesium silicate Nutrition 0.000 description 1
- ZADYMNAVLSWLEQ-UHFFFAOYSA-N magnesium;oxygen(2-);silicon(4+) Chemical compound [O-2].[O-2].[O-2].[Mg+2].[Si+4] ZADYMNAVLSWLEQ-UHFFFAOYSA-N 0.000 description 1
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000010445 mica Substances 0.000 description 1
- 229910052618 mica group Inorganic materials 0.000 description 1
- 230000001333 moisturizer Effects 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 108010032809 mucopolysaccharidase Proteins 0.000 description 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 description 1
- 150000005527 organic iodine compounds Chemical class 0.000 description 1
- 239000011368 organic material Substances 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000003415 peat Substances 0.000 description 1
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 description 1
- 239000010451 perlite Substances 0.000 description 1
- 235000019362 perlite Nutrition 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 238000005240 physical vapour deposition Methods 0.000 description 1
- 229960002702 piroxicam Drugs 0.000 description 1
- QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 108010064470 polyaspartate Proteins 0.000 description 1
- 229920001610 polycaprolactone Polymers 0.000 description 1
- 239000004632 polycaprolactone Substances 0.000 description 1
- 229920005906 polyester polyol Polymers 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920002643 polyglutamic acid Polymers 0.000 description 1
- 239000005056 polyisocyanate Substances 0.000 description 1
- 229920001228 polyisocyanate Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920005606 polypropylene copolymer Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 239000005033 polyvinylidene chloride Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 229940092258 rosemary extract Drugs 0.000 description 1
- 235000020748 rosemary extract Nutrition 0.000 description 1
- 239000001233 rosmarinus officinalis l. extract Substances 0.000 description 1
- IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 description 1
- 239000003352 sequestering agent Substances 0.000 description 1
- SCPYDCQAZCOKTP-UHFFFAOYSA-N silanol Chemical compound [SiH3]O SCPYDCQAZCOKTP-UHFFFAOYSA-N 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 229910021647 smectite Inorganic materials 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000011232 storage material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229910052715 tantalum Inorganic materials 0.000 description 1
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 238000009210 therapy by ultrasound Methods 0.000 description 1
- 229920002803 thermoplastic polyurethane Polymers 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- DVKJHBMWWAPEIU-UHFFFAOYSA-N toluene 2,4-diisocyanate Chemical compound CC1=CC=C(N=C=O)C=C1N=C=O DVKJHBMWWAPEIU-UHFFFAOYSA-N 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 229910021642 ultra pure water Inorganic materials 0.000 description 1
- 239000012498 ultrapure water Substances 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
- 229910001928 zirconium oxide Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F7/03—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F7/03—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
- A61F7/032—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction using oxygen from the air, e.g. pocket-stoves
- A61F7/034—Flameless
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0098—Heating or cooling appliances for medical or therapeutic treatment of the human body ways of manufacturing heating or cooling devices for therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0203—Cataplasms, poultices or compresses, characterised by their contents; Bags therefor
- A61F2007/0206—Cataplasms, poultices or compresses, characterised by their contents; Bags therefor containing organic solids or fibres
- A61F2007/0207—Plants, dried plants, seeds or fruits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0203—Cataplasms, poultices or compresses, characterised by their contents; Bags therefor
- A61F2007/022—Bags therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0225—Compresses or poultices for effecting heating or cooling connected to the body or a part thereof
- A61F2007/0226—Compresses or poultices for effecting heating or cooling connected to the body or a part thereof adhesive, self-sticking
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0244—Compresses or poultices for effecting heating or cooling with layers
- A61F2007/0257—Compresses or poultices for effecting heating or cooling with layers with a fluid impermeable layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0261—Compresses or poultices for effecting heating or cooling medicated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F7/03—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
- A61F7/032—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction using oxygen from the air, e.g. pocket-stoves
- A61F7/034—Flameless
- A61F2007/036—Fuels
- A61F2007/038—Carbon or charcoal, e.g. active
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24V—COLLECTION, PRODUCTION OR USE OF HEAT NOT OTHERWISE PROVIDED FOR
- F24V30/00—Apparatus or devices using heat produced by exothermal chemical reactions other than combustion
Abstract
発熱部(1)と、当該発熱部(1)を収容する収容体(2)と、当該収容体(2)の貼付面側に設けられた粘着層(3)と、当該粘着層(3)の貼付面側に設けられた離型シート(4)とを備える発熱具において、当該粘着層(3)に揮発性成分を含有させ、且つ当該収容体(2)の貼付面側を構成する第1包材(21)及び当該離型シート(4)のそれぞれに、ガスバリア層(211)(41)を設けることによって、保管中に揮発性成分を粘着層(3)中に安定に保持することが可能になり、その結果、保管中の発熱部(1)への揮発性成分の吸着を抑制でき、使用時に優れた温熱作用が発揮される。
Description
項1. 被着体に貼付して使用される発熱具であって、
被着体に伝える熱を発生させる発熱部と、
前記発熱部を収容し、被着体に貼付される貼付面を有する収容体と、
前記収容体の貼付面側に設けられた粘着層と、
前記粘着層の貼付面側に設けられた、前記粘着層から離型可能な離型シートと、を備え、
前記粘着層は、揮発性成分を含有し、
前記収容体の貼付面側に配される第1包材が、第1ガスバリア層を含み、
前記離型シートが、第2ガスバリア層を含む、
ことを特徴とする、発熱具。
項2. 前記第1包材の酸素透過度が1.5cc/m2・day・atm以下である、項1に記載の発熱具。
項3. 前記離型シートの酸素透過度が1.5cc/m2・day・atm以下である、項1又は2に記載の発熱具。
項4. 前記第1包材の水蒸気透過度が1.5g/m2・day・atm以下である、項1〜3のいずれかに記載の発熱具。
項5. 前記離型シートの水蒸気透過度が1.5g/m2・day・atm以下である、項1〜4のいずれかに記載の発熱具。
項6. 前記収容体が、前記第1包材と、貼付面とは反対側の面に配される第2包材とからなり、
前記収容体が、前記第1包材と前記第2包材の周縁部が接合された周縁接合部と、前記発熱部を収容するための空間を形成している収容部とを含み、
前記粘着層が、少なくとも、前記第1包材の前記周縁接合部を形成している領域に設けられている、項1〜5のいずれかに記載の発熱具。
項7. 前記揮発性成分が、メントール、カンフル、チモール、スピラントール、ハッカ油、ペパーミント油、サリチル酸メチル、カプサイシン、ノニル酸ワニリルアミド、セージ、カフェイン、ニコチン酸トコフェロール、ニコチン酸ベンジルエステル、バニリルブチルエーテル、バニリルエチルエーテル、ジンゲロール、バニリルプロピルエーテル、バニリルペンテルエーテル、バニリルヘキシルエーテル、バニリルブチルエーテルアセテート、トウガラシエキス、及び生姜エキスよりなる群から選択される少なくとも1種である、項1〜6のいずれかに記載の発熱具。
項8. 前記離型シートが、厚み方向に貫通する貫通部を有していない、項1〜7のいずれかに記載の発熱具。
本発明の発熱具は、発熱体として、被着体に伝える熱を発生させる発熱部1を備える。当該発熱部1は、発熱し、温感を付与する役割を果たす。
本発明の発熱具は、発熱部1を収容している収容体2を備える。収容体2は、前記発熱部1を収容するための収容部22を有している。
本発明の発熱具は、収容体2における前記貼付面に、揮発性成分を含む粘着層3が設けられる。このような粘着層3を設けることによって、被着体上に発熱具を固定するための固定具を別途使用することなく、被着体の所定部位に簡便に発熱具を貼付することが可能となる。また、粘着層3に揮発性成分が含まれていることにより、使用時に温熱作用と共に当該揮発性成分に基づく作用を発揮することができる。
が挙げられる。
本発明の発熱具は、粘着層3の表面(被着体に貼付される側)の全面に、第2ガスバリア層41を含む離型シート4が離型可能な状態で密着されている。このように、第2ガスバリア層41を有する離型シート4を粘着層3に密着させることによって、保管中に粘着層3に含まれる揮発性成分が密封袋内に揮散するのを抑制し、揮発性成分を粘着層3内で安定に保持させることが可能になる。
本発明の発熱具の好適な一形態の断面構造の概略図を図1及び2に示す。図1及び2に示す発熱具では、第1包材21と第2包材23の周縁部を接合することにより、収容部22と周縁接合部24とが形成され、更に収容部22と周縁接合部24の境界で段差2aがある収容体2が形成されている。収容体2中に、発熱部1として、酸素との接触により発熱する発熱性組成物が収容されている。図1に示す発熱具では、収容体2の第1包材21が、収容部22側から貼付面に向けて、溶着樹脂層212、金属箔膜からなる第1ガスバリア層211、及び繊維基材213がこの順で積層されている積層シートで構成されている。図2に示す発熱具では、収容体2の第1包材21が、収容部22側から貼付面に向けて、溶着樹脂層212、第1樹脂層214、蒸着膜からなる第1ガスバリア層211、及び繊維基材213がこの順で積層されている積層シートで構成されている。また、図1及び2に示す発熱具では、収容体2の第2包材23が、収容部22側から外側に向けて通気性樹脂層231及び繊維基材232がこの順で積層されている積層シートで形成されている。図1及び2に示す発熱具では、収容体2の第1包材21に粘着層3が積層され、更に粘着層3に対して、離型シート4が段差2aに追従して密着した状態になっている。また、図1及び2に示す発熱具では、離型シート4は、粘着層3側から、第2ガスバリア層41及び基材層42がこの順で積層されている積層シートで形成されている。また、図1に示す領域Eの拡大概略図を図3に示す。図3では、周縁接合部24において、離型シート4に凹凸形状が形成されおり、粘着層3、第1包材21、及び第2包材23を構成する各層でも、離型シート4の凹凸形状に追従するように凹凸形状が形成されている。
本発明の発熱具は、粘着層3を皮膚や衣類等の被着体に貼付することによって、身体の保温具又は治療用具として使用される。特に、本発明の発熱具は、優れた温熱作用を発揮できるので、血行促進、疼痛緩和、肩こり改善等のための治療用具として特に好適に使用される。
1.発熱具の製造
表1に示す層構成の非通気性積層シートからなる第1包材A〜D(縦13cm、横9.5cmの長方形)を準備した。また、各第1包材について、JIS K 7126−1:2006に規定されている差圧法に準じて、温度20℃、湿度90%RHの条件下で酸素透過度の測定を行った。更に、各第1包材について、JIS Z0208:1976に規定されているカップ法に準じて、温度40℃、湿度90%RHの条件下で水蒸気透過度の測定を行った。
<粘着層形成用組成物1>
メントール(商品名「薄荷脳」、長岡実業株式会社製) 5重量%
ゴム系粘着剤 95重量%
合計 100重量%
密封袋に収容した発熱具を50℃で2か月間保管した。製造直後及び2か月間保管後の発熱具の粘着層を剥がし取り、これをクロロホルムに加えて30分間超音波処理することにより、メントールの抽出を行った。次いで、抽出したメントール量をガスクロマトグラフィーにて測定し、粘着層中のメントール量を求めた。また、下記算出式に従って、粘着層のメントールの保持率を算出した。
製造直後の発熱具(実施例1及び比較例1)を密封袋に収容して50℃で2か月間保管した後に、発熱特性について評価した。具体的には、各10個の発熱具について、密封袋からから取り出し、密封袋から取り出した時点からJIS S 4100:2007に規定されている方法に従って、経時的に発熱温度の測定を行った。
1.発熱具の製造
(実施例6)
下記組成の粘着層形成用組成物2を使用したこと以外は、前記実施例1と同条件で発熱具を製造した。
<粘着層形成用組成物2>
メントール(商品名「薄荷脳」、長岡実業株式会社製) 5重量%
カンフル(商品名「dl−カンフル[SP]」、長岡実業株式会社製) 1.5重量%
生姜エキス(商品名「ショウガ抽出液」、アルプス薬品工業株式会社製)(液状)(乾燥原料換算で約0.12重量%に相当) 3重量%
ゴム系粘着剤 90.5重量%
合計 100重量%
第1包材D及び離型シートCを使用したこと以外は、前記実施例6と同条件で発熱具を製造した。
製造直後の発熱具(実施例6及び比較例4)を密封袋に収容して50℃で2か月間保管した後に、10名の被験者によって温感及び冷感について評価した。具体的には、被験者が座位で前腕を心臓と同じ高さの机においた姿勢を10分間保持した後に、机の上において、密閉袋から取り出した発熱具を前腕に直接貼付した。その後、50分間、5分間毎に呈される温感及び冷感を以下の判定基準に従って評点化し、その平均値を算出した。
(温感及び冷感の判定基準)
5:非常に強く感じる
4:強く感じる
3:感じる
2:やや弱く感じる
1:全く感じない
2 収容体
2a 段差(高低差)
21 第1包材
211 第1ガスバリア層
212 溶着樹脂層
213 繊維基材
214 第1樹脂層
22 収容部
23 第2包材
231 通気性樹脂層
232 繊維基材
24 周縁接合部
3 粘着層
4 離型シート
41 第2ガスバリア層
42 基材層
Claims (8)
- 被着体に貼付して使用される発熱具であって、
被着体に伝える熱を発生させる発熱部と、
前記発熱部を収容し、被着体に貼付される貼付面を有する収容体と、
前記収容体の貼付面側に設けられた粘着層と、
前記粘着層の貼付面側に設けられた、前記粘着層から離型可能な離型シートと、を備え、
前記粘着層は、揮発性成分を含有し、
前記収容体の貼付面側に配される第1包材が、第1ガスバリア層を含み、
前記離型シートが、第2ガスバリア層を含む、
ことを特徴とする、発熱具。 - 前記第1包材の酸素透過度が1.5cc/m2・day・atm以下である、請求項1に記載の発熱具。
- 前記離型シートの酸素透過度が1.5cc/m2・day・atm以下である、請求項1又は2に記載の発熱具。
- 前記第1包材の水蒸気透過度が1.5g/m2・day・atm以下である、請求項1〜3のいずれかに記載の発熱具。
- 前記離型シートの水蒸気透過度が1.5g/m2・day・atm以下である、請求項1〜4のいずれかに記載の発熱具。
- 前記収容体が、前記第1包材と、貼付面とは反対側の面に配される第2包材とからなり、
前記収容体が、前記第1包材と前記第2包材の周縁部が接合された周縁接合部と、前記発熱部を収容するための空間を形成している収容部とを含み、
前記粘着層が、少なくとも、前記第1包材の前記周縁接合部を形成している領域に設けられている、請求項1〜5のいずれかに記載の発熱具。 - 前記揮発性成分が、メントール、カンフル、チモール、スピラントール、ハッカ油、ペパーミント油、サリチル酸メチル、カプサイシン、ノニル酸ワニリルアミド、セージ、カフェイン、ニコチン酸トコフェロール、ニコチン酸ベンジルエステル、バニリルブチルエーテル、バニリルエチルエーテル、ジンゲロール、バニリルプロピルエーテル、バニリルペンテルエーテル、バニリルヘキシルエーテル、バニリルブチルエーテルアセテート、トウガラシエキス、及び生姜エキスよりなる群から選択される少なくとも1種である、請求項1〜6のいずれかに記載の発熱具。
- 前記離型シートが、厚み方向に貫通する貫通部を有していない、請求項1〜7のいずれかに記載の発熱具。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP2016/063608 WO2017191680A1 (ja) | 2016-05-02 | 2016-05-02 | 発熱具 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPWO2017191680A1 true JPWO2017191680A1 (ja) | 2019-03-14 |
JP6750007B2 JP6750007B2 (ja) | 2020-09-02 |
Family
ID=60203721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2018515381A Expired - Fee Related JP6750007B2 (ja) | 2016-05-02 | 2016-05-02 | 発熱具 |
Country Status (6)
Country | Link |
---|---|
US (1) | US10980665B2 (ja) |
EP (1) | EP3453364B1 (ja) |
JP (1) | JP6750007B2 (ja) |
CN (1) | CN109069289A (ja) |
HK (1) | HK1258221A1 (ja) |
WO (1) | WO2017191680A1 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014199986A1 (ja) * | 2013-06-10 | 2014-12-18 | 花王株式会社 | 温熱具 |
KR20230169479A (ko) | 2015-02-19 | 2023-12-15 | 캔디샌트 바이오메디컬 인코포레이티드 | 열 생성용 의료 장치 및 이를 이용한 치료 방법 |
JP6765356B2 (ja) * | 2017-09-01 | 2020-10-07 | ユニ・チャーム株式会社 | 温感物品 |
JP7296721B2 (ja) * | 2018-12-27 | 2023-06-23 | 小林製薬株式会社 | 鼻通り改善具 |
US11306946B2 (en) * | 2019-10-30 | 2022-04-19 | Ignik Outdoors, Inc. | Air-activated device-warming systems and methods |
WO2021214989A1 (ja) * | 2020-04-24 | 2021-10-28 | 花王株式会社 | 温熱具 |
CN114569327A (zh) * | 2022-03-30 | 2022-06-03 | 珠海横琴澳叶健康科技有限公司 | 一种缓解视疲劳的中药蒸气眼罩 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005170865A (ja) * | 2003-12-12 | 2005-06-30 | Toray Advanced Film Co Ltd | 医療用離型フィルムおよびその製造方法 |
WO2006006650A1 (ja) * | 2004-07-14 | 2006-01-19 | Mycoal Products Corporation | 発熱体及び発熱体の製造方法 |
JP2009248453A (ja) * | 2008-04-07 | 2009-10-29 | Dainippon Printing Co Ltd | 医療用離型フィルム |
JP2009274768A (ja) * | 2009-08-12 | 2009-11-26 | Nitto Denko Corp | 薬物含有粘着シートの包装構造 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN86108172A (zh) * | 1986-12-01 | 1987-08-12 | 吕景田 | 药物怀炉及制造方法 |
JPH07250860A (ja) * | 1991-07-09 | 1995-10-03 | Yutaka Tanahashi | 医療兼用適冷マット |
AU6076200A (en) * | 1999-07-08 | 2001-01-30 | Johnson & Johnson Consumer Companies, Inc. | Exothermic bandage |
JP2002360624A (ja) * | 2001-06-13 | 2002-12-17 | Nittetsu Fine Prod:Kk | 使い捨てカイロ |
WO2006006658A1 (ja) * | 2004-07-14 | 2006-01-19 | Mycoal Products Corporation | 足温用発熱体及び足温用発熱体の製造方法 |
US8246978B2 (en) * | 2007-07-10 | 2012-08-21 | Agile Therapeutics, Inc. | Dermal delivery device with reduced loss of its volatile components |
JP2010088590A (ja) * | 2008-10-07 | 2010-04-22 | Ooshin Mlp:Kk | 皮膚への直貼用温熱発生体構造物及びその製造方法 |
CN102227198B (zh) | 2008-12-10 | 2015-10-14 | 花王株式会社 | 发热器具 |
JP5788135B2 (ja) | 2008-12-10 | 2015-09-30 | 花王株式会社 | 発熱具 |
JP5593083B2 (ja) | 2010-02-05 | 2014-09-17 | 花王株式会社 | 発熱具 |
JP2013001435A (ja) * | 2011-06-17 | 2013-01-07 | Nitto Lifetech Kk | 袋体構成部材用多孔質フィルム及びカイロ用袋体構成部材 |
JP5905683B2 (ja) | 2011-08-24 | 2016-04-20 | 花王株式会社 | 発熱具 |
JP6636231B2 (ja) | 2012-08-01 | 2020-01-29 | 桐灰化学株式会社 | 発熱具 |
CN203576964U (zh) * | 2013-09-29 | 2014-05-07 | 中国热带农业科学院热带作物品种资源研究所 | 一种艾纳香膏药贴 |
JP6553337B2 (ja) | 2014-07-31 | 2019-07-31 | 小林製薬株式会社 | 使い捨てカイロ外袋用多層フィルム及び使い捨てカイロ |
JP6456705B2 (ja) * | 2015-01-29 | 2019-01-23 | 桐灰化学株式会社 | 発熱具 |
KR20180053693A (ko) * | 2015-09-11 | 2018-05-23 | 고바야시 세이야쿠 가부시키가이샤 | 발열기구 |
-
2016
- 2016-05-02 EP EP16901067.5A patent/EP3453364B1/en active Active
- 2016-05-02 CN CN201680085343.XA patent/CN109069289A/zh active Pending
- 2016-05-02 JP JP2018515381A patent/JP6750007B2/ja not_active Expired - Fee Related
- 2016-05-02 WO PCT/JP2016/063608 patent/WO2017191680A1/ja unknown
- 2016-05-02 US US16/098,065 patent/US10980665B2/en active Active
-
2019
- 2019-01-14 HK HK19100579.8A patent/HK1258221A1/zh unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005170865A (ja) * | 2003-12-12 | 2005-06-30 | Toray Advanced Film Co Ltd | 医療用離型フィルムおよびその製造方法 |
WO2006006650A1 (ja) * | 2004-07-14 | 2006-01-19 | Mycoal Products Corporation | 発熱体及び発熱体の製造方法 |
JP2009248453A (ja) * | 2008-04-07 | 2009-10-29 | Dainippon Printing Co Ltd | 医療用離型フィルム |
JP2009274768A (ja) * | 2009-08-12 | 2009-11-26 | Nitto Denko Corp | 薬物含有粘着シートの包装構造 |
Also Published As
Publication number | Publication date |
---|---|
US10980665B2 (en) | 2021-04-20 |
WO2017191680A1 (ja) | 2017-11-09 |
EP3453364B1 (en) | 2022-08-24 |
US20200046550A1 (en) | 2020-02-13 |
JP6750007B2 (ja) | 2020-09-02 |
CN109069289A (zh) | 2018-12-21 |
EP3453364A1 (en) | 2019-03-13 |
EP3453364A4 (en) | 2020-01-01 |
HK1258221A1 (zh) | 2019-11-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2017191680A1 (ja) | 発熱具 | |
WO2017043119A1 (ja) | 発熱具 | |
EP2810627B1 (en) | Heating tool | |
US20170360602A1 (en) | Heat generation tool | |
WO2014003096A1 (ja) | 発熱具 | |
TWI690310B (zh) | 發熱件 | |
WO2017191682A1 (ja) | 発熱具 | |
JP2007319359A (ja) | 発熱体 | |
JP2007136053A (ja) | 膏薬温熱用具 | |
WO2017191681A1 (ja) | 発熱具 | |
WO2017042947A1 (ja) | 発熱具 | |
JP2015029607A (ja) | 鼻通り改善具 | |
JP2019037775A (ja) | 温熱具 | |
JP2012245044A (ja) | 発熱用シートおよび発熱性貼付用具 | |
WO2017042948A1 (ja) | 発熱具 | |
WO2020137492A1 (ja) | 温熱治療用の医療機器 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20190408 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20200422 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20200618 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20200714 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20200812 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6750007 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
LAPS | Cancellation because of no payment of annual fees |