JPS6357440B2 - - Google Patents

Info

Publication number
JPS6357440B2
JPS6357440B2 JP58195931A JP19593183A JPS6357440B2 JP S6357440 B2 JPS6357440 B2 JP S6357440B2 JP 58195931 A JP58195931 A JP 58195931A JP 19593183 A JP19593183 A JP 19593183A JP S6357440 B2 JPS6357440 B2 JP S6357440B2
Authority
JP
Japan
Prior art keywords
interleukin
ifn
dna
amino acid
cysteine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP58195931A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5993093A (ja
Inventor
Efu Maaku Debitsuto
Esu Rin Reo
Yu Ru Shida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of JPS5993093A publication Critical patent/JPS5993093A/ja
Publication of JPS6357440B2 publication Critical patent/JPS6357440B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP58195931A 1982-10-19 1983-10-19 変形されたインターロイキン―２及びその製造方法 Granted JPS5993093A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43515482A 1982-10-19 1982-10-19
US435154 1982-10-19
US486162 1983-04-15

Publications (2)

Publication Number Publication Date
JPS5993093A JPS5993093A (ja) 1984-05-29
JPS6357440B2 true JPS6357440B2 (ref) 1988-11-11

Family

ID=23727220

Family Applications (4)

Application Number Title Priority Date Filing Date
JP58195931A Granted JPS5993093A (ja) 1982-10-19 1983-10-19 変形されたインターロイキン―２及びその製造方法
JP18730484A Pending JPS6128394A (ja) 1982-10-19 1984-09-08 部位特定突然変異用オリゴヌクレオチド
JP18730384A Granted JPS6128384A (ja) 1982-10-19 1984-09-08 変形されたインターフェロン―βをコードするＤＮＡ、このＤＮＡを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌
JP18730284A Granted JPS6128393A (ja) 1982-10-19 1984-09-08 変形されたインターロイキン―２をコードするｄｎａ、このｄｎａを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP18730484A Pending JPS6128394A (ja) 1982-10-19 1984-09-08 部位特定突然変異用オリゴヌクレオチド
JP18730384A Granted JPS6128384A (ja) 1982-10-19 1984-09-08 変形されたインターフェロン―βをコードするＤＮＡ、このＤＮＡを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌
JP18730284A Granted JPS6128393A (ja) 1982-10-19 1984-09-08 変形されたインターロイキン―２をコードするｄｎａ、このｄｎａを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌

Country Status (4)

Country Link
JP (4) JPS5993093A (ref)
IL (1) IL90047A (ref)
IN (1) IN161992B (ref)
ZA (1) ZA837789B (ref)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL76360A0 (en) 1984-09-26 1986-01-31 Takeda Chemical Industries Ltd Mutual separation of proteins
JP2675294B2 (ja) * 1984-10-15 1997-11-12 カイロン コーポレイション ヒト腫瘍壊死因子
WO1986002381A1 (en) * 1984-10-15 1986-04-24 Cetus Corporation Human tumor necrosis factor
US4572798A (en) * 1984-12-06 1986-02-25 Cetus Corporation Method for promoting disulfide bond formation in recombinant proteins
JP2583753B2 (ja) * 1984-12-21 1997-02-19 大塚製薬株式会社 抗腫瘍活性物質およびその製造法
JP2721854B2 (ja) * 1984-12-21 1998-03-04 大塚製薬株式会社 抗腫瘍活性物質
HU206520B (en) * 1985-04-22 1992-11-30 Genentech Inc Process for producing new human tissue plasminogen activator /tpa/ mutants and pharmaceutical compositions containing them
US4818698A (en) * 1985-08-23 1989-04-04 Toyo Jozo Co., Ltd. Polypeptides and preparation process thereof
NZ226543A (en) * 1987-10-22 1992-02-25 Merck & Co Inc Recombinant mutant acidic fibroblast growth factor
DE69025211T2 (de) * 1989-02-17 1996-09-19 Merck & Co Inc Protein-Antikrebsmittel
IL93723A (en) * 1989-03-22 1997-02-18 Merck & Co Inc Cystein modified truncated pseudomonas exotoxin A
US6207798B1 (en) 1989-08-03 2001-03-27 Merck & Co., Inc. Modified PE40 toxin fusion proteins
JPH0751621A (ja) * 1993-08-12 1995-02-28 Kansei Kogyo Kk 静電吸着による管内面更生工法
UY27373A1 (es) * 2001-07-09 2003-02-28 Schering Ag Formulaciones de interferón beta-humano
JP2007530419A (ja) * 2003-07-11 2007-11-01 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト 改良組換えヒトインターフェロン−β−１ｂポリペプチド
JP7610816B2 (ja) * 2020-04-29 2025-01-09 ジェノファーム インク． インターフェロンβ変異体と抗体が融合された組換えタンパク質およびそれを含む薬学的組成物

Also Published As

Publication number Publication date
ZA837789B (en) 1984-11-28
JPS6128394A (ja) 1986-02-08
JPS6128393A (ja) 1986-02-08
JPS6128384A (ja) 1986-02-08
JPH0380475B2 (ref) 1991-12-25
JPS5993093A (ja) 1984-05-29
IN161992B (ref) 1988-03-12
JPH057996B2 (ref) 1993-01-29
IL90047A (en) 1992-12-01

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