JPS6343669A - 血液処理器の製造方法 - Google Patents
血液処理器の製造方法Info
- Publication number
- JPS6343669A JPS6343669A JP61185358A JP18535886A JPS6343669A JP S6343669 A JPS6343669 A JP S6343669A JP 61185358 A JP61185358 A JP 61185358A JP 18535886 A JP18535886 A JP 18535886A JP S6343669 A JPS6343669 A JP S6343669A
- Authority
- JP
- Japan
- Prior art keywords
- blood
- manufacturing
- weight
- processing device
- urethane resin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008280 blood Substances 0.000 title claims description 61
- 210000004369 blood Anatomy 0.000 title claims description 61
- 238000004519 manufacturing process Methods 0.000 title claims description 24
- 239000012528 membrane Substances 0.000 claims description 50
- 229920001228 polyisocyanate Polymers 0.000 claims description 41
- 239000005056 polyisocyanate Substances 0.000 claims description 41
- 229920002803 thermoplastic polyurethane Polymers 0.000 claims description 28
- 230000001954 sterilising effect Effects 0.000 claims description 22
- 150000005846 sugar alcohols Polymers 0.000 claims description 20
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 19
- 239000000178 monomer Substances 0.000 claims description 18
- 229920000620 organic polymer Polymers 0.000 claims description 11
- 229920002678 cellulose Polymers 0.000 claims description 10
- UPMLOUAZCHDJJD-UHFFFAOYSA-N 4,4'-Diphenylmethane Diisocyanate Chemical compound C1=CC(N=C=O)=CC=C1CC1=CC=C(N=C=O)C=C1 UPMLOUAZCHDJJD-UHFFFAOYSA-N 0.000 claims description 8
- 238000000465 moulding Methods 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 7
- 239000001913 cellulose Substances 0.000 claims description 6
- 229920000219 Ethylene vinyl alcohol Polymers 0.000 claims description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 2
- 150000001408 amides Chemical class 0.000 claims description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims description 2
- 229920002492 poly(sulfone) Polymers 0.000 claims description 2
- 229920002239 polyacrylonitrile Polymers 0.000 claims description 2
- 239000004417 polycarbonate Substances 0.000 claims description 2
- 229920000515 polycarbonate Polymers 0.000 claims description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 2
- 239000004926 polymethyl methacrylate Substances 0.000 claims 1
- 239000012510 hollow fiber Substances 0.000 description 27
- 238000004659 sterilization and disinfection Methods 0.000 description 20
- 230000023555 blood coagulation Effects 0.000 description 13
- 239000004359 castor oil Substances 0.000 description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- 235000019438 castor oil Nutrition 0.000 description 9
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 8
- 239000000853 adhesive Substances 0.000 description 7
- 230000001070 adhesive effect Effects 0.000 description 7
- 235000010980 cellulose Nutrition 0.000 description 6
- 239000012153 distilled water Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 235000011187 glycerol Nutrition 0.000 description 6
- 210000003734 kidney Anatomy 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 239000002994 raw material Substances 0.000 description 5
- 125000003118 aryl group Chemical group 0.000 description 4
- 238000005520 cutting process Methods 0.000 description 4
- 150000002334 glycols Chemical class 0.000 description 4
- 229920005989 resin Polymers 0.000 description 4
- 239000011347 resin Substances 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 150000001298 alcohols Chemical class 0.000 description 3
- 125000001931 aliphatic group Chemical group 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 3
- 238000001631 haemodialysis Methods 0.000 description 3
- 230000000322 hemodialysis Effects 0.000 description 3
- 239000002504 physiological saline solution Substances 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 2
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 description 2
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 2
- 239000002202 Polyethylene glycol Substances 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000004202 carbamide Substances 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 150000002314 glycerols Chemical class 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 239000004014 plasticizer Substances 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- 238000006116 polymerization reaction Methods 0.000 description 2
- 229920001451 polypropylene glycol Polymers 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- DVKJHBMWWAPEIU-UHFFFAOYSA-N toluene 2,4-diisocyanate Chemical compound CC1=CC=C(N=C=O)C=C1N=C=O DVKJHBMWWAPEIU-UHFFFAOYSA-N 0.000 description 2
- FKTHNVSLHLHISI-UHFFFAOYSA-N 1,2-bis(isocyanatomethyl)benzene Chemical compound O=C=NCC1=CC=CC=C1CN=C=O FKTHNVSLHLHISI-UHFFFAOYSA-N 0.000 description 1
- MTZUIIAIAKMWLI-UHFFFAOYSA-N 1,2-diisocyanatobenzene Chemical compound O=C=NC1=CC=CC=C1N=C=O MTZUIIAIAKMWLI-UHFFFAOYSA-N 0.000 description 1
- OVBFMUAFNIIQAL-UHFFFAOYSA-N 1,4-diisocyanatobutane Chemical compound O=C=NCCCCN=C=O OVBFMUAFNIIQAL-UHFFFAOYSA-N 0.000 description 1
- AXIWPQKLPMINAT-UHFFFAOYSA-N 1-ethyl-2,3-diisocyanatobenzene Chemical compound CCC1=CC=CC(N=C=O)=C1N=C=O AXIWPQKLPMINAT-UHFFFAOYSA-N 0.000 description 1
- 229920001747 Cellulose diacetate Polymers 0.000 description 1
- DQEFEBPAPFSJLV-UHFFFAOYSA-N Cellulose propionate Chemical compound CCC(=O)OCC1OC(OC(=O)CC)C(OC(=O)CC)C(OC(=O)CC)C1OC1C(OC(=O)CC)C(OC(=O)CC)C(OC(=O)CC)C(COC(=O)CC)O1 DQEFEBPAPFSJLV-UHFFFAOYSA-N 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- HEBKCHPVOIAQTA-QWWZWVQMSA-N D-arabinitol Chemical compound OC[C@@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-QWWZWVQMSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 239000005057 Hexamethylene diisocyanate Substances 0.000 description 1
- JCELWOGDGMAGGN-UHFFFAOYSA-N N=C=O.N=C=O.C1=CC=CC=C1C(C=1C=CC=CC=1)C1=CC=CC=C1 Chemical compound N=C=O.N=C=O.C1=CC=CC=C1C(C=1C=CC=CC=1)C1=CC=CC=C1 JCELWOGDGMAGGN-UHFFFAOYSA-N 0.000 description 1
- CCFQKJBRMQOAFR-UHFFFAOYSA-N N=C=O.N=C=O.CCC1=CC=CC=C1CC Chemical compound N=C=O.N=C=O.CCC1=CC=CC=C1CC CCFQKJBRMQOAFR-UHFFFAOYSA-N 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- FJWGYAHXMCUOOM-QHOUIDNNSA-N [(2s,3r,4s,5r,6r)-2-[(2r,3r,4s,5r,6s)-4,5-dinitrooxy-2-(nitrooxymethyl)-6-[(2r,3r,4s,5r,6s)-4,5,6-trinitrooxy-2-(nitrooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-3,5-dinitrooxy-6-(nitrooxymethyl)oxan-4-yl] nitrate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O)O[C@H]1[C@@H]([C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@@H](CO[N+]([O-])=O)O1)O[N+]([O-])=O)CO[N+](=O)[O-])[C@@H]1[C@@H](CO[N+]([O-])=O)O[C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O FJWGYAHXMCUOOM-QHOUIDNNSA-N 0.000 description 1
- 238000007259 addition reaction Methods 0.000 description 1
- 125000002723 alicyclic group Chemical group 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 229920006218 cellulose propionate Polymers 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 235000019414 erythritol Nutrition 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000002615 hemofiltration Methods 0.000 description 1
- RRAMGCGOFNQTLD-UHFFFAOYSA-N hexamethylene diisocyanate Chemical compound O=C=NCCCCCCN=C=O RRAMGCGOFNQTLD-UHFFFAOYSA-N 0.000 description 1
- 229920006158 high molecular weight polymer Polymers 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 231100000989 no adverse effect Toxicity 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 1
- 229920006393 polyether sulfone Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- -1 triedylamine Chemical compound 0.000 description 1
Landscapes
- External Artificial Organs (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61185358A JPS6343669A (ja) | 1986-08-08 | 1986-08-08 | 血液処理器の製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61185358A JPS6343669A (ja) | 1986-08-08 | 1986-08-08 | 血液処理器の製造方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4292999A Division JPH07121278B2 (ja) | 1992-10-30 | 1992-10-30 | 血液処理器の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6343669A true JPS6343669A (ja) | 1988-02-24 |
| JPH0379021B2 JPH0379021B2 (enExample) | 1991-12-17 |
Family
ID=16169391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61185358A Granted JPS6343669A (ja) | 1986-08-08 | 1986-08-08 | 血液処理器の製造方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6343669A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04231795A (ja) * | 1990-06-22 | 1992-08-20 | Degussa Ag | 断熱成形体、その製造方法および該成形体からなる容器ならびに冷蔵庫および冷凍庫における断熱材 |
Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51128880A (en) * | 1975-05-02 | 1976-11-10 | Nippon Zeon Co | Method of securing yarn bundle end to case |
| JPS5329360A (en) * | 1976-08-31 | 1978-03-18 | Okura Ind Co Ltd | Compositions consisting mainly of chaff |
| JPS5418476A (en) * | 1977-07-12 | 1979-02-10 | Teijin Ltd | Separating unit for fluid by use if hollow fiber |
| JPS5442420A (en) * | 1977-07-05 | 1979-04-04 | Cordis Dow Corp | Improved cellulose acetate hollow fiber and production thereof |
| JPS54132698A (en) * | 1978-03-25 | 1979-10-15 | Akzo Nv | Polyurethane sealing material and preparing same |
| JPS5527053A (en) * | 1978-08-15 | 1980-02-26 | Toray Ind Inc | Selectively permeable hollow filament and preparing the same |
| JPS57143510A (en) * | 1981-03-03 | 1982-09-04 | Asahi Chem Ind Co Ltd | Production of high-flux hollow fiber regenerated from cuprammonium cellulose |
| JPS59225066A (ja) * | 1983-06-03 | 1984-12-18 | テルモ株式会社 | 血液処理装置の製造方法 |
| JPS607496A (ja) * | 1983-06-28 | 1985-01-16 | 松下電器産業株式会社 | 音声認識装置 |
| JPS6020016A (ja) * | 1983-07-15 | 1985-02-01 | Matsushita Electric Ind Co Ltd | 燃焼装置 |
| JPS6058210A (ja) * | 1983-09-08 | 1985-04-04 | Toyobo Co Ltd | セルロ−スエステル系中空糸膜の製造方法 |
| JPS6058156A (ja) * | 1983-09-08 | 1985-04-04 | 三洋化成工業株式会社 | シ−ル材および人工臓器 |
| JPS60166007A (ja) * | 1984-02-06 | 1985-08-29 | Terumo Corp | 透析用中空繊維の製造方法 |
| JPS62136208A (ja) * | 1985-12-09 | 1987-06-19 | Asahi Chem Ind Co Ltd | 結束材及び分離装置 |
-
1986
- 1986-08-08 JP JP61185358A patent/JPS6343669A/ja active Granted
Patent Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51128880A (en) * | 1975-05-02 | 1976-11-10 | Nippon Zeon Co | Method of securing yarn bundle end to case |
| JPS5329360A (en) * | 1976-08-31 | 1978-03-18 | Okura Ind Co Ltd | Compositions consisting mainly of chaff |
| JPS5442420A (en) * | 1977-07-05 | 1979-04-04 | Cordis Dow Corp | Improved cellulose acetate hollow fiber and production thereof |
| JPS5418476A (en) * | 1977-07-12 | 1979-02-10 | Teijin Ltd | Separating unit for fluid by use if hollow fiber |
| JPS54132698A (en) * | 1978-03-25 | 1979-10-15 | Akzo Nv | Polyurethane sealing material and preparing same |
| JPS5527053A (en) * | 1978-08-15 | 1980-02-26 | Toray Ind Inc | Selectively permeable hollow filament and preparing the same |
| JPS57143510A (en) * | 1981-03-03 | 1982-09-04 | Asahi Chem Ind Co Ltd | Production of high-flux hollow fiber regenerated from cuprammonium cellulose |
| JPS59225066A (ja) * | 1983-06-03 | 1984-12-18 | テルモ株式会社 | 血液処理装置の製造方法 |
| JPS607496A (ja) * | 1983-06-28 | 1985-01-16 | 松下電器産業株式会社 | 音声認識装置 |
| JPS6020016A (ja) * | 1983-07-15 | 1985-02-01 | Matsushita Electric Ind Co Ltd | 燃焼装置 |
| JPS6058210A (ja) * | 1983-09-08 | 1985-04-04 | Toyobo Co Ltd | セルロ−スエステル系中空糸膜の製造方法 |
| JPS6058156A (ja) * | 1983-09-08 | 1985-04-04 | 三洋化成工業株式会社 | シ−ル材および人工臓器 |
| JPS60166007A (ja) * | 1984-02-06 | 1985-08-29 | Terumo Corp | 透析用中空繊維の製造方法 |
| JPS62136208A (ja) * | 1985-12-09 | 1987-06-19 | Asahi Chem Ind Co Ltd | 結束材及び分離装置 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04231795A (ja) * | 1990-06-22 | 1992-08-20 | Degussa Ag | 断熱成形体、その製造方法および該成形体からなる容器ならびに冷蔵庫および冷凍庫における断熱材 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0379021B2 (enExample) | 1991-12-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Cancellation because of no payment of annual fees |