JPS6317841B2 - - Google Patents
Info
- Publication number
- JPS6317841B2 JPS6317841B2 JP52057512A JP5751277A JPS6317841B2 JP S6317841 B2 JPS6317841 B2 JP S6317841B2 JP 52057512 A JP52057512 A JP 52057512A JP 5751277 A JP5751277 A JP 5751277A JP S6317841 B2 JPS6317841 B2 JP S6317841B2
- Authority
- JP
- Japan
- Prior art keywords
- support material
- groups
- isocyanate
- reactive groups
- biologically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/62—Polymers of compounds having carbon-to-carbon double bonds
- C08G18/6216—Polymers of alpha-beta ethylenically unsaturated carboxylic acids or of derivatives thereof
- C08G18/6266—Polymers of amides or imides from alpha-beta ethylenically unsaturated carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/30—Low-molecular-weight compounds
- C08G18/38—Low-molecular-weight compounds having heteroatoms other than oxygen
- C08G18/3893—Low-molecular-weight compounds having heteroatoms other than oxygen containing silicon
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/64—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63
- C08G18/6484—Polysaccharides and derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S8/00—Bleaching and dyeing; fluid treatment and chemical modification of textiles and fibers
- Y10S8/11—Isocyanate and carbonate modification of fibers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Peptides Or Proteins (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762621974 DE2621974A1 (de) | 1976-05-18 | 1976-05-18 | Verfahren zur herstellung eines zur kovalenten bindung mit biologisch aktivem material befaehigten traegermaterials |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS52140588A JPS52140588A (en) | 1977-11-24 |
| JPS6317841B2 true JPS6317841B2 (https=) | 1988-04-15 |
Family
ID=5978226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5751277A Granted JPS52140588A (en) | 1976-05-18 | 1977-05-18 | Vehicle substance capable of covalent combination with biologically active substance* and process for preparing the same |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4177038A (https=) |
| JP (1) | JPS52140588A (https=) |
| CH (1) | CH641479A5 (https=) |
| DE (1) | DE2621974A1 (https=) |
| FR (1) | FR2351990A1 (https=) |
| GB (1) | GB1569446A (https=) |
| IL (1) | IL52119A (https=) |
| SE (1) | SE7705543L (https=) |
Families Citing this family (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1083508A (fr) * | 1975-11-13 | 1980-08-12 | Jacques Grange | Supports porteurs de chaines laterales, procedes d'obtention de ces supports, procedes de fixation de composes organiques comportant un residu glucidique sur lesdits supports, produits et reactifs resultant de ladite fixation chimique |
| US4267280A (en) * | 1977-02-07 | 1981-05-12 | Mccormick Charles L | Controlled release pesticides and method of preparation |
| DE2834539A1 (de) | 1978-08-07 | 1980-02-21 | Basf Ag | Makroporoese polymere als traegermaterial zur kovalenten bindung von proteinen |
| SE450834B (sv) * | 1980-11-19 | 1987-08-03 | Biocompat Inc | Sett att binda ett protein till en berare innehallande hydroxylgrupper |
| US4582805A (en) * | 1982-05-03 | 1986-04-15 | The Dow Chemical Company | Immobilization of biological matter via copolymers of isocyanatoalkyl esters |
| US4496479A (en) * | 1983-05-18 | 1985-01-29 | Syntex (U.S.A.) Company | Chloramphenicol derivatives, antigens and antibodies |
| GB8334499D0 (en) * | 1983-12-24 | 1984-02-01 | Beecham Group Plc | Derivatives |
| US4478938A (en) * | 1984-03-02 | 1984-10-23 | The Dow Chemical Company | Process for crosslinking polyamines |
| US4530905A (en) * | 1984-10-25 | 1985-07-23 | The Dow Chemical Company | Crosslinked gelatin foams |
| US4748121A (en) * | 1984-11-30 | 1988-05-31 | Ppg Industries, Inc. | Porous glass fibers with immobilized biochemically active material |
| DE3782394T2 (de) * | 1986-03-28 | 1993-05-19 | Toray Industries | Immobilisiertes, physiologisch aktives material. |
| US5144013A (en) * | 1986-09-24 | 1992-09-01 | Ube Industries, Ltd. | Body fluid purifying material and method for purifying body fluid by use thereof |
| US4933285A (en) * | 1986-10-07 | 1990-06-12 | Environmental Technologies Group, Inc. | Multiple monolayers of polymeric linkages on a solid phase for immobilizing macromolecules |
| US4954444A (en) * | 1987-03-02 | 1990-09-04 | E. I. Du Pont De Nemours And Company | Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports |
| US5240602A (en) * | 1987-06-08 | 1993-08-31 | Chromatochem, Inc. | Chromatographic material |
| US6251278B1 (en) * | 1987-06-08 | 2001-06-26 | Chromatochem, Inc. | Process for separating a substance from a mixture |
| CA1336077C (en) * | 1987-11-10 | 1995-06-27 | Ruben G. Carbonell | Chromatography apparatus and method and material for making the same |
| JP2761881B2 (ja) * | 1988-03-10 | 1998-06-04 | チッソ株式会社 | 抗体を固定化したアフイニテイクロマトグラフイ用担体 |
| US5277813A (en) * | 1988-06-17 | 1994-01-11 | S.A.C. Corporation | Shielded stationary phases |
| US4940737A (en) * | 1988-11-02 | 1990-07-10 | W. R. Grace & Co.-Conn | Chemically modified hydrophilic prepolymers and polymers |
| US5091176A (en) * | 1988-11-02 | 1992-02-25 | W. R. Grace & Co.-Conn. | Polymer-modified peptide drugs having enhanced biological and pharmacological activities |
| US5045190A (en) * | 1988-11-08 | 1991-09-03 | Carbonell Ruben G | Chromatography apparatus |
| US5240601A (en) * | 1988-11-09 | 1993-08-31 | Chembiomed, Ltd. | Affinity supports for hemoperfusion |
| US5149425A (en) * | 1988-11-09 | 1992-09-22 | Chembiomed, Ltd. | Affinity supports for hemoperfusion |
| US5043062A (en) * | 1989-02-21 | 1991-08-27 | Eastman Kodak Company | High performance affinity chromatography column comprising non-porous, nondisperse polymeric packing material |
| EP0386926A3 (en) * | 1989-03-02 | 1991-12-18 | Supelco, Inc. | Silica gel supports suitable for chromatographic separations |
| US5135866A (en) * | 1989-03-03 | 1992-08-04 | W. R. Grace & Co.-Conn. | Very low protein nutrient medium for cell culture |
| US5085779A (en) * | 1989-06-07 | 1992-02-04 | J. T. Baker, Inc. | Polyethyleneimine matrixes for affinity chromatography |
| US5092992A (en) * | 1989-06-07 | 1992-03-03 | J. T. Baker Inc. | Polyethyleneimine matrixes for affinity chromatography |
| US5270193A (en) * | 1989-10-27 | 1993-12-14 | E. I. Dupont De Nemours And Company | Immobilization of biomolecules on perfluorocarbon surfaces |
| US5354461A (en) * | 1991-02-20 | 1994-10-11 | Eisai Co., Ltd. | Packings combining protein to a support via a spacer |
| CA2061519C (en) * | 1991-02-20 | 2004-05-18 | Naoki Asakawa | Packings combining protein to a support via a spacer |
| US5403750A (en) * | 1991-03-06 | 1995-04-04 | W. R. Grace & Co.-Conn. | Biocompatible, low protein adsorption affinity matrix |
| US5178756A (en) * | 1991-06-25 | 1993-01-12 | Jarrett Iii Harry W | Glucose-silica medium for high-pressure gel filtration chromatography |
| FR2678380B1 (fr) * | 1991-06-28 | 1993-10-08 | Sebia | Dispositif permettant l'etalement d'un ou plusieurs reactifs sur un gel. |
| CA2064683A1 (en) * | 1992-03-26 | 1993-09-27 | Krishna Mohan Rao Kallury | Formation of thermostable enzymes with extra-ordinary heat tolerance by immobilization on phospholipid matrices |
| US5334640A (en) * | 1992-04-08 | 1994-08-02 | Clover Consolidated, Ltd. | Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods |
| GB9407886D0 (en) * | 1994-04-21 | 1994-06-15 | Ici Plc | Purification process |
| US5662802A (en) * | 1994-07-07 | 1997-09-02 | Ionics, Incorporated | Solvent extraction process using water absorbing solvent at preselected temperature |
| US5869127A (en) * | 1995-02-22 | 1999-02-09 | Boston Scientific Corporation | Method of providing a substrate with a bio-active/biocompatible coating |
| US6558798B2 (en) | 1995-02-22 | 2003-05-06 | Scimed Life Systems, Inc. | Hydrophilic coating and substrates coated therewith having enhanced durability and lubricity |
| CA2214088A1 (en) * | 1995-03-03 | 1996-09-12 | Metabolex Inc. | Novel encapsulation process by a gelling polymer |
| US5916790A (en) * | 1995-03-03 | 1999-06-29 | Metabolex, Inc. | Encapsulation compositions, and methods |
| US5874214A (en) * | 1995-04-25 | 1999-02-23 | Irori | Remotely programmable matrices with memories |
| US6331273B1 (en) | 1995-04-25 | 2001-12-18 | Discovery Partners International | Remotely programmable matrices with memories |
| US6416714B1 (en) | 1995-04-25 | 2002-07-09 | Discovery Partners International, Inc. | Remotely programmable matrices with memories |
| US6329139B1 (en) | 1995-04-25 | 2001-12-11 | Discovery Partners International | Automated sorting system for matrices with memory |
| US5741462A (en) * | 1995-04-25 | 1998-04-21 | Irori | Remotely programmable matrices with memories |
| US5751629A (en) * | 1995-04-25 | 1998-05-12 | Irori | Remotely programmable matrices with memories |
| US6247995B1 (en) | 1996-02-06 | 2001-06-19 | Bruce Bryan | Bioluminescent novelty items |
| US5876995A (en) * | 1996-02-06 | 1999-03-02 | Bryan; Bruce | Bioluminescent novelty items |
| US6416960B1 (en) | 1996-08-08 | 2002-07-09 | Prolume, Ltd. | Detection and visualization of neoplastic tissues and other tissues |
| IL129767A0 (en) | 1996-12-12 | 2000-02-29 | Prolume Ltd | Apparatus and method for detecting and identifying infectious agents |
| JP2002507410A (ja) | 1998-03-27 | 2002-03-12 | プロルーム・リミテッド | ルシフェラーゼ、蛍光タンパク質、ルシフェラーゼおよび蛍光タンパク質をコードする核酸および、診断、高処理スクリーニングおよび新規アイテムにおけるその使用 |
| EP1925320A3 (en) | 1998-03-27 | 2008-09-03 | Prolume, Ltd. | Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics |
| FR2785200B1 (fr) * | 1998-10-30 | 2001-03-30 | Centre Nat Rech Scient | Utilisation d'un gel adsorbant pour eliminer et purifier les biomolecules |
| GB9909245D0 (en) | 1999-04-22 | 1999-06-16 | Univ Cranfield | Reactive polymers and their application in reactions and assays |
| US7192729B2 (en) | 1999-07-06 | 2007-03-20 | General Atomics | Methods for assaying homocysteine |
| SE9904197D0 (sv) * | 1999-11-22 | 1999-11-22 | Amersham Pharm Biotech Ab | A method for anion exchange adsorption on matrices carrying mixed mode ligands |
| AU2001227679A1 (en) * | 2000-02-25 | 2001-09-03 | General Atomics | Mutant nucleic binding enzymes and use thereof in diagnostic, detection and purification methods |
| WO2001068240A2 (en) * | 2000-03-14 | 2001-09-20 | Hammen Corporation | Composite matrices with interstitial polymer networks |
| US7109315B2 (en) | 2000-03-15 | 2006-09-19 | Bruce J. Bryan | Renilla reniformis fluorescent proteins, nucleic acids encoding the fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items |
| US6686461B1 (en) | 2000-03-22 | 2004-02-03 | Solulink Bioscience, Inc. | Triphosphate oligonucleotide modification reagents and uses thereof |
| US7102024B1 (en) | 2000-08-01 | 2006-09-05 | Schwartz David A | Functional biopolymer modification reagents and uses thereof |
| US6610504B1 (en) | 2000-04-10 | 2003-08-26 | General Atomics | Methods of determining SAM-dependent methyltransferase activity using a mutant SAH hydrolase |
| JP2004513981A (ja) * | 2000-07-17 | 2004-05-13 | プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ | 生物種の吸着に耐える表面 |
| GB0027047D0 (en) * | 2000-11-06 | 2000-12-20 | Ici Plc | Process for reducing the concentration of undesired compounds in a composition |
| US7201844B1 (en) | 2001-03-14 | 2007-04-10 | Hammen Corporation | Composite matrices with interstital polymer networks |
| US6802966B2 (en) * | 2001-08-14 | 2004-10-12 | W. R. Grace & Co. Conn. | Solid compositions for selective adsorption from complex mixtures |
| US6987079B2 (en) * | 2001-08-14 | 2006-01-17 | W.R. Grace & Co.-Conn. | Supported catalyst systems |
| WO2003062402A2 (en) * | 2002-01-24 | 2003-07-31 | Pointilliste, Inc. | Use of collections of binding sites for sample profiling and other applications |
| WO2004051231A1 (ja) * | 2002-11-29 | 2004-06-17 | Nec Corporation | 分離装置および分離方法 |
| KR100528959B1 (ko) * | 2003-02-11 | 2005-11-16 | 학교법인 포항공과대학교 | 쿠커비투릴이 결합된 실리카 겔 |
| US7384760B2 (en) * | 2004-04-30 | 2008-06-10 | General Atomics | Methods for assaying inhibitors of S-adenosylhomocysteine (SAH) hydrolase and S-adenosylmethionine (SAM)-dependent methyltransferase |
| US7402243B2 (en) | 2004-09-10 | 2008-07-22 | Dionex Corporation | Organosilanes and substrate bonded with same |
| US7439062B2 (en) * | 2004-12-23 | 2008-10-21 | Biocept, Inc. | Beads for capturing target cells from bodily fluid |
| US7468130B2 (en) * | 2005-02-15 | 2008-12-23 | Dionex Corporation | Organosilanes and substrates covalently bonded with same and methods for synthesis and use same |
| US7557232B2 (en) * | 2007-05-25 | 2009-07-07 | Dionex Corporation | Compositions useful as chromatography stationary phases |
| BRPI1009421A2 (pt) * | 2009-03-12 | 2016-03-01 | Shiseido Co Ltd | método para a fabricação de material de recheio, material de recheio e coluna |
| CN102939140B (zh) * | 2010-05-19 | 2015-05-20 | 迪奥内克斯公司 | 具有芳香族堆积特性的官能化的基质 |
| DE102016001407A1 (de) | 2016-02-09 | 2017-08-24 | Fresenius Medical Care Deutschland Gmbh | Blutbehandlung mit Inaktivierung von freien Nukleinsäuren |
| BR112018016240A2 (pt) * | 2016-02-11 | 2019-01-02 | Htg Molecular Diagnostics Inc | método de sequência alvo direta que utiliza proteção da nuclease |
| BR112019001171B1 (pt) * | 2016-07-22 | 2022-08-16 | Nutrition & Biosciences Usa 4, Inc | Polímero de poliuretano, composição de poliuretano, espuma de poliuretano e substrato fibroso revestido |
| CN110951273A (zh) * | 2019-12-24 | 2020-04-03 | 黑龙江幸福人生态农业开发股份有限公司 | 一种生物质表面改性方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3574062A (en) * | 1967-04-20 | 1971-04-06 | Beckman Instruments Inc | Method of immobilizing enzymes and product |
| US3705084A (en) * | 1970-03-18 | 1972-12-05 | Monsanto Co | Macroporous enzyme reactor |
| US3672955A (en) * | 1970-05-20 | 1972-06-27 | Us Agriculture | Preparation of an insoluble active enzyme |
| CS167530B1 (en) * | 1972-03-29 | 1976-04-29 | Jiri Coupek | Method of insoluble biologically active compounds preparation |
| US3929574A (en) * | 1972-05-03 | 1975-12-30 | Grace W R & Co | Use of enzymes bound to polyurethane |
| JPS4928031A (https=) * | 1972-07-18 | 1974-03-13 | ||
| JPS5118518B2 (https=) * | 1973-03-07 | 1976-06-10 | ||
| JPS5117197B2 (https=) * | 1973-10-23 | 1976-05-31 | ||
| US3905923A (en) * | 1974-04-04 | 1975-09-16 | Minnesota Mining & Mfg | Poly (urea-urethane) foams containing immobilized active enzymes |
| US3947352A (en) * | 1974-05-31 | 1976-03-30 | Pedro Cuatrecasas | Polysaccharide matrices for use as adsorbents in affinity chromatography techniques |
| SE434848B (sv) * | 1976-04-22 | 1984-08-20 | Purdue Research Foundation | Forfaringssett for framstellning av porosa cellulosaperlor |
| US4063017A (en) * | 1976-04-22 | 1977-12-13 | Purdue Research Foundation | Porous cellulose beads and the immobilization of enzymes therewith |
-
1976
- 1976-05-18 DE DE19762621974 patent/DE2621974A1/de not_active Withdrawn
-
1977
- 1977-05-12 SE SE7705543A patent/SE7705543L/xx not_active Application Discontinuation
- 1977-05-17 GB GB19216/77A patent/GB1569446A/en not_active Expired
- 1977-05-17 US US05/797,677 patent/US4177038A/en not_active Expired - Lifetime
- 1977-05-17 CH CH615077A patent/CH641479A5/de not_active IP Right Cessation
- 1977-05-18 JP JP5751277A patent/JPS52140588A/ja active Granted
- 1977-05-18 FR FR7715261A patent/FR2351990A1/fr active Granted
- 1977-05-18 IL IL52119A patent/IL52119A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH641479A5 (de) | 1984-02-29 |
| SE7705543L (sv) | 1977-11-19 |
| JPS52140588A (en) | 1977-11-24 |
| US4177038A (en) | 1979-12-04 |
| IL52119A0 (en) | 1977-07-31 |
| GB1569446A (en) | 1980-06-18 |
| FR2351990A1 (fr) | 1977-12-16 |
| IL52119A (en) | 1980-12-31 |
| FR2351990B1 (https=) | 1983-06-24 |
| DE2621974A1 (de) | 1977-11-24 |
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