JPS63164858A - 軟カプセルの外皮 - Google Patents
軟カプセルの外皮Info
- Publication number
- JPS63164858A JPS63164858A JP61309109A JP30910986A JPS63164858A JP S63164858 A JPS63164858 A JP S63164858A JP 61309109 A JP61309109 A JP 61309109A JP 30910986 A JP30910986 A JP 30910986A JP S63164858 A JPS63164858 A JP S63164858A
- Authority
- JP
- Japan
- Prior art keywords
- parts
- gum
- alginic acid
- polyhydric alcohol
- alkali
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007901 soft capsule Substances 0.000 title claims abstract description 25
- 150000005846 sugar alcohols Polymers 0.000 claims abstract description 18
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 16
- 239000005017 polysaccharide Substances 0.000 claims abstract description 16
- 150000004804 polysaccharides Chemical class 0.000 claims abstract description 16
- 239000000203 mixture Substances 0.000 claims abstract description 15
- 238000004898 kneading Methods 0.000 claims abstract description 9
- 235000010443 alginic acid Nutrition 0.000 claims abstract description 8
- 239000000783 alginic acid Substances 0.000 claims abstract description 8
- 229920000615 alginic acid Polymers 0.000 claims abstract description 8
- 229960001126 alginic acid Drugs 0.000 claims abstract description 8
- 150000004781 alginic acids Chemical class 0.000 claims abstract description 8
- 239000003513 alkali Substances 0.000 claims abstract description 8
- LUEWUZLMQUOBSB-FSKGGBMCSA-N (2s,3s,4s,5s,6r)-2-[(2r,3s,4r,5r,6s)-6-[(2r,3s,4r,5s,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5s,6r)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@@H](OC3[C@H](O[C@@H](O)[C@@H](O)[C@H]3O)CO)[C@@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-FSKGGBMCSA-N 0.000 claims abstract description 7
- 229920002581 Glucomannan Polymers 0.000 claims abstract description 7
- 235000010418 carrageenan Nutrition 0.000 claims abstract description 7
- 239000000679 carrageenan Substances 0.000 claims abstract description 7
- 229920001525 carrageenan Polymers 0.000 claims abstract description 7
- 229940113118 carrageenan Drugs 0.000 claims abstract description 7
- 229940046240 glucomannan Drugs 0.000 claims abstract description 7
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims abstract description 7
- 150000002772 monosaccharides Chemical class 0.000 claims abstract description 6
- 229920001542 oligosaccharide Polymers 0.000 claims abstract description 6
- 150000002482 oligosaccharides Chemical class 0.000 claims abstract description 6
- 239000000126 substance Substances 0.000 claims abstract description 6
- 229920001285 xanthan gum Polymers 0.000 claims abstract description 5
- 239000000230 xanthan gum Substances 0.000 claims abstract description 5
- 235000010493 xanthan gum Nutrition 0.000 claims abstract description 5
- 229940082509 xanthan gum Drugs 0.000 claims abstract description 5
- 229920001817 Agar Polymers 0.000 claims abstract description 4
- 229920002101 Chitin Polymers 0.000 claims abstract description 4
- 229920000858 Cyclodextrin Polymers 0.000 claims abstract description 4
- 229920002907 Guar gum Polymers 0.000 claims abstract description 4
- 229920000161 Locust bean gum Polymers 0.000 claims abstract description 4
- 239000004373 Pullulan Substances 0.000 claims abstract description 4
- 229920001218 Pullulan Polymers 0.000 claims abstract description 4
- 240000004584 Tamarindus indica Species 0.000 claims abstract description 4
- 235000004298 Tamarindus indica Nutrition 0.000 claims abstract description 4
- 239000008272 agar Substances 0.000 claims abstract description 4
- 235000010419 agar Nutrition 0.000 claims abstract description 4
- 239000000665 guar gum Substances 0.000 claims abstract description 4
- 235000010417 guar gum Nutrition 0.000 claims abstract description 4
- 229960002154 guar gum Drugs 0.000 claims abstract description 4
- 235000010420 locust bean gum Nutrition 0.000 claims abstract description 4
- 239000000711 locust bean gum Substances 0.000 claims abstract description 4
- 229920001277 pectin Polymers 0.000 claims abstract description 4
- 235000010987 pectin Nutrition 0.000 claims abstract description 4
- 239000001814 pectin Substances 0.000 claims abstract description 4
- 229960000292 pectin Drugs 0.000 claims abstract description 4
- 235000019423 pullulan Nutrition 0.000 claims abstract description 4
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims abstract description 4
- 150000002016 disaccharides Chemical class 0.000 claims abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract description 13
- 239000000243 solution Substances 0.000 abstract description 11
- 239000000463 material Substances 0.000 abstract description 9
- 239000002994 raw material Substances 0.000 abstract description 5
- 238000000034 method Methods 0.000 abstract description 3
- 229920000591 gum Polymers 0.000 abstract 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 12
- 108010010803 Gelatin Proteins 0.000 description 9
- 239000008273 gelatin Substances 0.000 description 9
- 229920000159 gelatin Polymers 0.000 description 9
- 235000019322 gelatine Nutrition 0.000 description 9
- 235000011852 gelatine desserts Nutrition 0.000 description 9
- 235000011187 glycerol Nutrition 0.000 description 7
- 239000007788 liquid Substances 0.000 description 6
- 235000018102 proteins Nutrition 0.000 description 6
- 108090000623 proteins and genes Proteins 0.000 description 6
- 102000004169 proteins and genes Human genes 0.000 description 6
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 4
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 4
- 239000002775 capsule Substances 0.000 description 4
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 108010025899 gelatin film Proteins 0.000 description 3
- ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical compound [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
- 241000287828 Gallus gallus Species 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 239000001099 ammonium carbonate Substances 0.000 description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 238000005266 casting Methods 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 238000000354 decomposition reaction Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- 235000011194 food seasoning agent Nutrition 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- -1 pentasaccharides Polymers 0.000 description 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
- 239000000600 sorbitol Substances 0.000 description 2
- 235000010356 sorbitol Nutrition 0.000 description 2
- 235000014347 soups Nutrition 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 229960004793 sucrose Drugs 0.000 description 2
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- QCVGEOXPDFCNHA-UHFFFAOYSA-N 5,5-dimethyl-2,4-dioxo-1,3-oxazolidine-3-carboxamide Chemical compound CC1(C)OC(=O)N(C(N)=O)C1=O QCVGEOXPDFCNHA-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 229910000013 Ammonium bicarbonate Inorganic materials 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 108010016626 Dipeptides Proteins 0.000 description 1
- 239000004278 EU approved seasoning Substances 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 244000017020 Ipomoea batatas Species 0.000 description 1
- 235000002678 Ipomoea batatas Nutrition 0.000 description 1
- 239000002211 L-ascorbic acid Substances 0.000 description 1
- 235000000069 L-ascorbic acid Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 102000014171 Milk Proteins Human genes 0.000 description 1
- 108010011756 Milk Proteins Proteins 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- 108010073771 Soybean Proteins Proteins 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 235000012538 ammonium bicarbonate Nutrition 0.000 description 1
- 235000012501 ammonium carbonate Nutrition 0.000 description 1
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- RQPZNWPYLFFXCP-UHFFFAOYSA-L barium dihydroxide Chemical compound [OH-].[OH-].[Ba+2] RQPZNWPYLFFXCP-UHFFFAOYSA-L 0.000 description 1
- 229910001863 barium hydroxide Inorganic materials 0.000 description 1
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 1
- 239000000920 calcium hydroxide Substances 0.000 description 1
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 235000013681 dietary sucrose Nutrition 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 235000014103 egg white Nutrition 0.000 description 1
- 210000000969 egg white Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 1
- 239000001095 magnesium carbonate Substances 0.000 description 1
- 229910000021 magnesium carbonate Inorganic materials 0.000 description 1
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 description 1
- 239000000347 magnesium hydroxide Substances 0.000 description 1
- 229910001862 magnesium hydroxide Inorganic materials 0.000 description 1
- 239000000845 maltitol Substances 0.000 description 1
- 235000010449 maltitol Nutrition 0.000 description 1
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 description 1
- 229940035436 maltitol Drugs 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 229960001855 mannitol Drugs 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 235000021239 milk protein Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 230000002797 proteolythic effect Effects 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 229960002920 sorbitol Drugs 0.000 description 1
- 235000019710 soybean protein Nutrition 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Grain Derivatives (AREA)
- Seeds, Soups, And Other Foods (AREA)
- Jellies, Jams, And Syrups (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP61309109A JPS63164858A (ja) | 1986-12-27 | 1986-12-27 | 軟カプセルの外皮 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP61309109A JPS63164858A (ja) | 1986-12-27 | 1986-12-27 | 軟カプセルの外皮 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS63164858A true JPS63164858A (ja) | 1988-07-08 |
JPH0457305B2 JPH0457305B2 (enrdf_load_stackoverflow) | 1992-09-11 |
Family
ID=17988995
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP61309109A Granted JPS63164858A (ja) | 1986-12-27 | 1986-12-27 | 軟カプセルの外皮 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS63164858A (enrdf_load_stackoverflow) |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0852912A3 (en) * | 1996-12-20 | 1998-07-22 | Societe Des Produits Nestle S.A. | Encapsulated liquid product |
FR2767070A1 (fr) * | 1997-08-08 | 1999-02-12 | Laurence Paris | Composition visqueuses aqueuses, limpides ou non, pour la fabrication de capsules molles et de capsules dures, et procede de fabrication de films pour de telles capsules |
US6340473B1 (en) | 1999-07-07 | 2002-01-22 | R.P. Scherer Technologies, Inc. | Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same |
WO2003004003A1 (fr) * | 2001-07-05 | 2003-01-16 | Wakunaga Pharmaceutical Co., Ltd. | Capsules molles |
WO2003008495A1 (en) * | 2001-07-19 | 2003-01-30 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Pullulan-containing powder, process for producing the same and use thereof |
WO2003009832A1 (en) * | 2001-07-24 | 2003-02-06 | Cardinal Health Australia 401 Pty Ltd | Non-gelatin based capsules |
WO2004096283A1 (ja) * | 2003-05-02 | 2004-11-11 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | ソフトカプセル皮膜及びソフトカプセル |
US6887307B1 (en) | 1999-07-22 | 2005-05-03 | Warner-Lambert Company, Llc | Pullulan film compositions |
US7189843B2 (en) | 2000-12-13 | 2007-03-13 | Fmc Corporation | Production of carrageenan and carrageenan products |
JP2007525551A (ja) * | 2003-04-14 | 2007-09-06 | エフ エム シー コーポレーション | カッパ−2カラゲニンを含有する均一で熱可逆性のゲルフィルム及びそれからつくったソフトカプセル |
WO2006059180A3 (en) * | 2004-12-03 | 2008-01-17 | Council Scient Ind Res | Process of preparation of biodegradable films from semi refined kappa carrageenan |
JP2008519075A (ja) * | 2004-11-08 | 2008-06-05 | アール.ピー. シェーラー テクノロジーズ インコーポレイテッド | 非ゼラチン軟質カプセルシステム |
US8820331B2 (en) | 2005-06-21 | 2014-09-02 | V. Mane Fils | Smoking device incorporating a breakable capsule, breakable capsule and process for manufacturing said capsule |
CN112772921A (zh) * | 2021-01-18 | 2021-05-11 | 卓翠琴 | 一种具有润肺止咳功效的柠檬膏及其制备方法 |
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JPS6012943A (ja) * | 1983-07-05 | 1985-01-23 | Ajinomoto Co Inc | 軟カプセルの製法 |
JPS6012941A (ja) * | 1983-07-05 | 1985-01-23 | Ajinomoto Co Inc | 軟カプセルの製造方法 |
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JPS6012943A (ja) * | 1983-07-05 | 1985-01-23 | Ajinomoto Co Inc | 軟カプセルの製法 |
JPS6012941A (ja) * | 1983-07-05 | 1985-01-23 | Ajinomoto Co Inc | 軟カプセルの製造方法 |
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EP0852912A3 (en) * | 1996-12-20 | 1998-07-22 | Societe Des Produits Nestle S.A. | Encapsulated liquid product |
FR2767070A1 (fr) * | 1997-08-08 | 1999-02-12 | Laurence Paris | Composition visqueuses aqueuses, limpides ou non, pour la fabrication de capsules molles et de capsules dures, et procede de fabrication de films pour de telles capsules |
WO1999007347A1 (fr) * | 1997-08-08 | 1999-02-18 | Laurence Paris | Compositions visqueuses aqueuses, limpides ou non, pour la fabrication de capsules molles et de capsules dures, et procede de fabrication de films pour de telles capsules |
US6340473B1 (en) | 1999-07-07 | 2002-01-22 | R.P. Scherer Technologies, Inc. | Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same |
JP2007126470A (ja) * | 1999-07-07 | 2007-05-24 | Rp Scherer Technologies Inc | 改質澱粉とイオタ−カラギーナンとを含有するフィルム形成性組成物およびこれを用いる軟質カプセルの製造方法 |
US6582727B2 (en) | 1999-07-07 | 2003-06-24 | R. P. Scherer Technologies, Inc. | Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same |
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US6887307B1 (en) | 1999-07-22 | 2005-05-03 | Warner-Lambert Company, Llc | Pullulan film compositions |
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US7772211B2 (en) | 2000-12-13 | 2010-08-10 | Fmc Corporation | Production of carrageenan and carrageenan products |
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US7846475B2 (en) | 2001-07-05 | 2010-12-07 | Wakunaga Pharmaceutical Co., Ltd. | Soft capsules |
WO2003004003A1 (fr) * | 2001-07-05 | 2003-01-16 | Wakunaga Pharmaceutical Co., Ltd. | Capsules molles |
US8821934B2 (en) | 2001-07-19 | 2014-09-02 | Hayashibara Co., Ltd. | Pullulan-containing powder, process for producing the same and use thereof |
WO2003008495A1 (en) * | 2001-07-19 | 2003-01-30 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Pullulan-containing powder, process for producing the same and use thereof |
AU2002317040B2 (en) * | 2001-07-24 | 2008-08-14 | R.P. Scherer Technologies Llc | Non-gelatin based capsules |
WO2003009832A1 (en) * | 2001-07-24 | 2003-02-06 | Cardinal Health Australia 401 Pty Ltd | Non-gelatin based capsules |
JP2007525551A (ja) * | 2003-04-14 | 2007-09-06 | エフ エム シー コーポレーション | カッパ−2カラゲニンを含有する均一で熱可逆性のゲルフィルム及びそれからつくったソフトカプセル |
JP2007526209A (ja) * | 2003-04-14 | 2007-09-13 | エフ エム シー コーポレーション | 均一かつ熱可逆性低粘度ポリマンナンフィルムの伝達システム |
WO2004096283A1 (ja) * | 2003-05-02 | 2004-11-11 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | ソフトカプセル皮膜及びソフトカプセル |
JP2011153147A (ja) * | 2003-05-02 | 2011-08-11 | Hayashibara Biochem Lab Inc | ソフトカプセル皮膜及びソフトカプセル |
JPWO2004096283A1 (ja) * | 2003-05-02 | 2006-07-13 | 株式会社林原生物化学研究所 | ソフトカプセル皮膜及びソフトカプセル |
JP2008519075A (ja) * | 2004-11-08 | 2008-06-05 | アール.ピー. シェーラー テクノロジーズ インコーポレイテッド | 非ゼラチン軟質カプセルシステム |
WO2006059180A3 (en) * | 2004-12-03 | 2008-01-17 | Council Scient Ind Res | Process of preparation of biodegradable films from semi refined kappa carrageenan |
GB2435768B (en) * | 2004-12-03 | 2010-06-16 | Council Scient Ind Res | Process of preparation of biodegradable films from semi refined kappa carrageenan |
US8820331B2 (en) | 2005-06-21 | 2014-09-02 | V. Mane Fils | Smoking device incorporating a breakable capsule, breakable capsule and process for manufacturing said capsule |
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