JPS6254319B2 - - Google Patents
Info
- Publication number
- JPS6254319B2 JPS6254319B2 JP55046003A JP4600380A JPS6254319B2 JP S6254319 B2 JPS6254319 B2 JP S6254319B2 JP 55046003 A JP55046003 A JP 55046003A JP 4600380 A JP4600380 A JP 4600380A JP S6254319 B2 JPS6254319 B2 JP S6254319B2
- Authority
- JP
- Japan
- Prior art keywords
- mycoplanesin
- chloroform
- color
- absorption spectrum
- measured
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 241000894006 Bacteria Species 0.000 claims description 4
- 238000004458 analytical method Methods 0.000 claims description 3
- 230000003115 biocidal effect Effects 0.000 claims description 3
- 238000012258 culturing Methods 0.000 claims description 3
- NDWOINLWKNMGFD-UHFFFAOYSA-N mycoplanecin c Chemical compound CC1OC(=O)CNC(=O)C(CCCCC)N(C)C(=O)C2CCCN2C(=O)C(C(C)C)N(C)C(=O)C(CCC(C)C)NC(=O)C2CC(C)CN2C(=O)C(CC(C)C)NC(=O)C1N(C)C(=O)C1CC(CC)CN1C(=O)C(C(C)C)N(C)C(=O)C(=O)CC NDWOINLWKNMGFD-UHFFFAOYSA-N 0.000 claims description 3
- 239000003242 anti bacterial agent Substances 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 12
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims 8
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 6
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims 6
- 238000000862 absorption spectrum Methods 0.000 claims 6
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 4
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims 4
- HEDRZPFGACZZDS-MICDWDOJSA-N Trichloro(2H)methane Chemical compound [2H]C(Cl)(Cl)Cl HEDRZPFGACZZDS-MICDWDOJSA-N 0.000 claims 4
- 238000000655 nuclear magnetic resonance spectrum Methods 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 3
- YNXFKYXSWNIWGO-LURJTMIESA-N (2s)-1-ethylpyrrolidin-1-ium-2-carboxylate Chemical compound CCN1CCC[C@H]1C(O)=O YNXFKYXSWNIWGO-LURJTMIESA-N 0.000 claims 2
- HORQAOAYAYGIBM-UHFFFAOYSA-N 2,4-dinitrophenylhydrazine Chemical compound NNC1=CC=C([N+]([O-])=O)C=C1[N+]([O-])=O HORQAOAYAYGIBM-UHFFFAOYSA-N 0.000 claims 2
- 241000187844 Actinoplanes Species 0.000 claims 2
- 241000187712 Actinoplanes sp. Species 0.000 claims 2
- 239000004471 Glycine Substances 0.000 claims 2
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims 2
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 2
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 2
- CWLQUGTUXBXTLF-UHFFFAOYSA-N N-methyl-L-proline monohydrate Natural products CN1CCCC1C(O)=O CWLQUGTUXBXTLF-UHFFFAOYSA-N 0.000 claims 2
- CWLQUGTUXBXTLF-YFKPBYRVSA-N N-methylproline Chemical compound CN1CCC[C@H]1C(O)=O CWLQUGTUXBXTLF-YFKPBYRVSA-N 0.000 claims 2
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 2
- 238000010521 absorption reaction Methods 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 238000000921 elemental analysis Methods 0.000 claims 2
- 230000007062 hydrolysis Effects 0.000 claims 2
- 238000006460 hydrolysis reaction Methods 0.000 claims 2
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims 2
- 238000002844 melting Methods 0.000 claims 2
- 230000008018 melting Effects 0.000 claims 2
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 claims 2
- 239000012286 potassium permanganate Substances 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 239000000741 silica gel Substances 0.000 claims 2
- 229910002027 silica gel Inorganic materials 0.000 claims 2
- CZDYPVPMEAXLPK-UHFFFAOYSA-N tetramethylsilane Chemical compound C[Si](C)(C)C CZDYPVPMEAXLPK-UHFFFAOYSA-N 0.000 claims 2
- 238000004809 thin layer chromatography Methods 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 230000000877 morphologic effect Effects 0.000 description 3
- 230000001766 physiological effect Effects 0.000 description 3
- 241000186361 Actinobacteria <class> Species 0.000 description 2
- 241000187747 Streptomyces Species 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 241000203809 Actinomycetales Species 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 208000031295 Animal disease Diseases 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 210000003495 flagella Anatomy 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000004816 paper chromatography Methods 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4600380A JPS56142250A (en) | 1980-04-08 | 1980-04-08 | Antibiotic, mycoplanecin c, and its preparation |
| US06/250,709 US4370266A (en) | 1980-04-07 | 1981-04-03 | Mycoplanecin derivatives and their preparation |
| EP81301502A EP0037736B1 (en) | 1980-04-07 | 1981-04-07 | Mycoplanecin derivatives, their preparation and pharmaceutical compositions containing them |
| DE8181301502T DE3160382D1 (en) | 1980-04-07 | 1981-04-07 | Mycoplanecin derivatives, their preparation and pharmaceutical compositions containing them |
| AT81301502T ATE3635T1 (de) | 1980-04-07 | 1981-04-07 | Mycoplanecin-derivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4600380A JPS56142250A (en) | 1980-04-08 | 1980-04-08 | Antibiotic, mycoplanecin c, and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56142250A JPS56142250A (en) | 1981-11-06 |
| JPS6254319B2 true JPS6254319B2 (enrdf_load_stackoverflow) | 1987-11-13 |
Family
ID=12734893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4600380A Granted JPS56142250A (en) | 1980-04-07 | 1980-04-08 | Antibiotic, mycoplanecin c, and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56142250A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0312946U (enrdf_load_stackoverflow) * | 1989-06-14 | 1991-02-08 | ||
| WO2021074746A1 (en) | 2019-10-16 | 2021-04-22 | 3M Innovative Properties Company | Substituted benzimidazole melt additives |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100385152B1 (ko) * | 2001-03-14 | 2003-05-23 | 씨제이 주식회사 | 카프레오마이신의 정제방법 |
-
1980
- 1980-04-08 JP JP4600380A patent/JPS56142250A/ja active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0312946U (enrdf_load_stackoverflow) * | 1989-06-14 | 1991-02-08 | ||
| WO2021074746A1 (en) | 2019-10-16 | 2021-04-22 | 3M Innovative Properties Company | Substituted benzimidazole melt additives |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS56142250A (en) | 1981-11-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE68925002T2 (de) | Verfahren zur Herstellung von optisch-aktiven alpha-substituierten organischen Säuren und Mikroorganismen und Enzyme, die dafür verwendet werden. | |
| JPS61268187A (ja) | 新規抗生物質ｓｋ−１０７１およびその製造法 | |
| JPS6254319B2 (enrdf_load_stackoverflow) | ||
| JP2863934B2 (ja) | 抗生物質プラスバシン | |
| JPS6024717B2 (ja) | 抗生物質マイコプラネシン | |
| JPS5920360B2 (ja) | ７−アミノセフアロスポラン酸および其の誘導体の製造法 | |
| RU2038376C1 (ru) | Штамм бактерий yersinia pestis, предназначенный для определения строения и функции новой дополнительной плазмиды мол.м. 19 мд у возбудителя чумы из таласского очага | |
| RU2031938C1 (ru) | Штамм бактерий yersinia pestis - продуцент фракции i чумного микроба | |
| JP2642707B2 (ja) | 抗生物質ムレイドマイシンｅ，ｆおよびその誘導体 | |
| JP2001008694A (ja) | Ｄ−キロ−イノシトールの新規製造方法 | |
| JPS6312080B2 (enrdf_load_stackoverflow) | ||
| JP2640932B2 (ja) | Ｔａｎ−８６６、その製造法および微生物 | |
| JPS6178377A (ja) | イースト菌細胞の生長禁止を増大させる方法 | |
| JPH0361662B2 (enrdf_load_stackoverflow) | ||
| JP4235298B2 (ja) | 抗生物質パレイン酸ａとその製造法 | |
| JPH0331720B2 (enrdf_load_stackoverflow) | ||
| JPH0249717B2 (enrdf_load_stackoverflow) | ||
| JPH0141158B2 (enrdf_load_stackoverflow) | ||
| JPS6216640B2 (enrdf_load_stackoverflow) | ||
| JPS6332798B2 (enrdf_load_stackoverflow) | ||
| JPS58107186A (ja) | 制癌作用物質及びその製造法 | |
| JPH0578380A (ja) | ペプチフルオリンおよびネオペプチフルオリン | |
| JPS62118882A (ja) | Ｌ−アルギニンオキシダ−ゼ及びその製造法 | |
| JPS5819679B2 (ja) | 新規抗生物質及びその製法 | |
| JPS5818384A (ja) | 抗生物質およびその製造法 |