JPS6245842B2 - - Google Patents
Info
- Publication number
- JPS6245842B2 JPS6245842B2 JP12915478A JP12915478A JPS6245842B2 JP S6245842 B2 JPS6245842 B2 JP S6245842B2 JP 12915478 A JP12915478 A JP 12915478A JP 12915478 A JP12915478 A JP 12915478A JP S6245842 B2 JPS6245842 B2 JP S6245842B2
- Authority
- JP
- Japan
- Prior art keywords
- biotin
- water
- dextrin
- ammonia
- aqueous solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims description 112
- 229960002685 biotin Drugs 0.000 claims description 56
- 235000020958 biotin Nutrition 0.000 claims description 56
- 239000011616 biotin Substances 0.000 claims description 56
- 229920001353 Dextrin Polymers 0.000 claims description 30
- 239000004375 Dextrin Substances 0.000 claims description 30
- 235000019425 dextrin Nutrition 0.000 claims description 30
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 25
- 229920002472 Starch Polymers 0.000 claims description 20
- 235000019698 starch Nutrition 0.000 claims description 20
- 239000008107 starch Substances 0.000 claims description 20
- 238000000354 decomposition reaction Methods 0.000 claims description 19
- 239000007864 aqueous solution Substances 0.000 claims description 17
- 238000002360 preparation method Methods 0.000 claims description 16
- 229910021529 ammonia Inorganic materials 0.000 claims description 11
- 238000001694 spray drying Methods 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 31
- 238000000034 method Methods 0.000 description 14
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 11
- 238000004090 dissolution Methods 0.000 description 9
- 239000000203 mixture Substances 0.000 description 8
- 239000007788 liquid Substances 0.000 description 5
- 239000002245 particle Substances 0.000 description 4
- 239000007921 spray Substances 0.000 description 4
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonium chloride Substances [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 3
- 235000011114 ammonium hydroxide Nutrition 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 239000003651 drinking water Substances 0.000 description 2
- 235000020188 drinking water Nutrition 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 244000144972 livestock Species 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000012798 spherical particle Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- 241000251468 Actinopterygii Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- VCUFZILGIRCDQQ-KRWDZBQOSA-N N-[[(5S)-2-oxo-3-(2-oxo-3H-1,3-benzoxazol-6-yl)-1,3-oxazolidin-5-yl]methyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C1O[C@H](CN1C1=CC2=C(NC(O2)=O)C=C1)CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F VCUFZILGIRCDQQ-KRWDZBQOSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000003674 animal food additive Substances 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- 239000008121 dextrose Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 239000013067 intermediate product Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12915478A JPS5555112A (en) | 1978-10-19 | 1978-10-19 | Preparation of biotin preparation rapidly soluble in water |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12915478A JPS5555112A (en) | 1978-10-19 | 1978-10-19 | Preparation of biotin preparation rapidly soluble in water |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5555112A JPS5555112A (en) | 1980-04-22 |
JPS6245842B2 true JPS6245842B2 (de) | 1987-09-29 |
Family
ID=15002469
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12915478A Granted JPS5555112A (en) | 1978-10-19 | 1978-10-19 | Preparation of biotin preparation rapidly soluble in water |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5555112A (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4098376B2 (ja) * | 1996-09-05 | 2008-06-11 | ビーエーエスエフ ソシエタス・ヨーロピア | 錠剤特性の優れた水溶性ビタミン組成物およびその製造法 |
JP3295033B2 (ja) | 1998-03-19 | 2002-06-24 | コナミ株式会社 | ゲームシステムおよびそれに用いるコンピュータ読み取り可能な記録媒体 |
JP2001181211A (ja) * | 1999-12-24 | 2001-07-03 | Sumitomo Chem Co Ltd | 水溶性ビタミン粉剤 |
-
1978
- 1978-10-19 JP JP12915478A patent/JPS5555112A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS5555112A (en) | 1980-04-22 |
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