JPS6242914B2 - - Google Patents

Info

Publication number
JPS6242914B2
JPS6242914B2 JP55060736A JP6073680A JPS6242914B2 JP S6242914 B2 JPS6242914 B2 JP S6242914B2 JP 55060736 A JP55060736 A JP 55060736A JP 6073680 A JP6073680 A JP 6073680A JP S6242914 B2 JPS6242914 B2 JP S6242914B2
Authority
JP
Japan
Prior art keywords
mmole
chloroform
camptothecin
little
hydrogen peroxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP55060736A
Other languages
English (en)
Japanese (ja)
Other versions
JPS56158786A (en
Inventor
Sada Myasaka
Masahiko Mutai
Seigo Sawada
Kenichiro Nogata
Hisao Hagiwara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yakult Honsha Co Ltd
Original Assignee
Yakult Honsha Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yakult Honsha Co Ltd filed Critical Yakult Honsha Co Ltd
Priority to JP6073680A priority Critical patent/JPS56158786A/ja
Priority to US06/166,953 priority patent/US4399282A/en
Priority to IT23348/80A priority patent/IT1199976B/it
Priority to AU60273/80A priority patent/AU536181B2/en
Priority to GB8022438A priority patent/GB2056973B/en
Priority to CH5265/80A priority patent/CH648316A5/de
Priority to DE19803026172 priority patent/DE3026172A1/de
Priority to FR8015418A priority patent/FR2462437A1/fr
Priority to DE3051054A priority patent/DE3051054C2/de
Priority to AR281720A priority patent/AR228575A1/es
Priority to NLAANVRAGE8003988,A priority patent/NL188219C/xx
Publication of JPS56158786A publication Critical patent/JPS56158786A/ja
Priority to US06/676,248 priority patent/USRE32518E/en
Publication of JPS6242914B2 publication Critical patent/JPS6242914B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP6073680A 1979-07-10 1980-05-09 Novel camptothecin derivative and its preparation Granted JPS56158786A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
JP6073680A JPS56158786A (en) 1980-05-09 1980-05-09 Novel camptothecin derivative and its preparation
US06/166,953 US4399282A (en) 1979-07-10 1980-07-08 Camptothecin derivatives
IT23348/80A IT1199976B (it) 1979-07-10 1980-07-09 Derivati della camptotecima e processi per la loro preparazione
AU60273/80A AU536181B2 (en) 1979-07-10 1980-07-09 Derivatives of camptothecin
GB8022438A GB2056973B (en) 1979-07-10 1980-07-09 Camptothecin derivatives useful as antitumour agents
CH5265/80A CH648316A5 (de) 1979-07-10 1980-07-09 Camptothecinderivate und verfahren zu ihrer herstellung.
FR8015418A FR2462437A1 (fr) 1979-07-10 1980-07-10 Nouveaux derives de la camptothecine doues d'activite antitumorale et leur procede de preparation
DE19803026172 DE3026172A1 (de) 1979-07-10 1980-07-10 Camptothecinderivate und ihre herstellung
DE3051054A DE3051054C2 (enrdf_load_html_response) 1980-05-09 1980-07-10
AR281720A AR228575A1 (es) 1979-07-10 1980-07-10 Procedimiento para obtener derivados de 7-hidroximetil o 7-carboxicamptotecina y sus sales
NLAANVRAGE8003988,A NL188219C (nl) 1979-07-10 1980-07-10 Camptothecinederivaten, werkwijze voor het bereiden daarvan, farmaceutische preparaten met anti-tumorwerking, werkwijze voor het bereiden daarvan.
US06/676,248 USRE32518E (en) 1979-07-10 1984-11-29 Camptothecin derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6073680A JPS56158786A (en) 1980-05-09 1980-05-09 Novel camptothecin derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS56158786A JPS56158786A (en) 1981-12-07
JPS6242914B2 true JPS6242914B2 (enrdf_load_html_response) 1987-09-10

Family

ID=13150837

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6073680A Granted JPS56158786A (en) 1979-07-10 1980-05-09 Novel camptothecin derivative and its preparation

Country Status (2)

Country Link
JP (1) JPS56158786A (enrdf_load_html_response)
DE (1) DE3051054C2 (enrdf_load_html_response)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8476438B2 (en) 2006-04-27 2013-07-02 Kabushiki Kaisha Yakult Honsha Process for production of camptothecin derivative

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8476438B2 (en) 2006-04-27 2013-07-02 Kabushiki Kaisha Yakult Honsha Process for production of camptothecin derivative

Also Published As

Publication number Publication date
DE3051054C2 (enrdf_load_html_response) 1991-07-04
JPS56158786A (en) 1981-12-07

Similar Documents

Publication Publication Date Title
USRE32518E (en) Camptothecin derivatives
JP3848837B2 (ja) 新規な中間体、それを用いたマイクロライド系抗生物質の製造方法
JP2003055368A (ja) ケミカルプロセス
JPS6242914B2 (enrdf_load_html_response)
JP2524804B2 (ja) 新規なカンプトテシン誘導体及びその製造法
EP0093945B1 (en) 1,4-dihydropyridine derivatives
JPH0532399B2 (enrdf_load_html_response)
JPH0453877B2 (enrdf_load_html_response)
JP2003286244A (ja) Ｎ−フェニルビス（トリフルオロメタンスルホンイミド）の製造方法
JPH05148293A (ja) 新規カプラマイシン誘導体およびその製造方法
WO2014094511A1 (zh) 一种制备曲前列尼尔的中间体、其制备方法以及通过其制备曲前列尼尔的方法
JP3298929B2 (ja) カルボン酸エステル又はカルボン酸チオエステルの新規製造方法
JPH0561271B2 (enrdf_load_html_response)
JPH029585B2 (enrdf_load_html_response)
US6723853B2 (en) Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
JP3290172B1 (ja) ２−アミノフェノキサジン−３−オン誘導体又は３−アミノフェノキサジン−２−オン誘導体を製造する方法
JP3009716B2 (ja) 新規なカンプトテシン誘導体
Takeuchi et al. Development of dual-acting agents for thromboxane receptor antagonism and thromboxane synthase inhibition-I. Synthesis, structure-activity relationship, and evaluation of substituted (ω-phenyl-ω)-(3-pyridyl) alkenoic acids
HUP0100841A2 (hu) 4,5-Epoximorfinán-6-olok glikozidálása
CN103387587A (zh) 恩替卡韦中间体及其制备方法
Holliday Stereoselective Synthesis of (+)-and (-)-cananodine
JP2710837B2 (ja) 光学活性β―ヒドロキシチオエステルの製造方法
JP3055234B2 (ja) スピロピリドピラン系化合物及びそれを使用したグアニンインディケーター
JP2743121B2 (ja) 一酸化窒素合成阻害剤
JP3037816B2 (ja) ピラノインドリジンジオン誘導体の製法