JPS62155215A - 抗腫瘍活性増強剤 - Google Patents

抗腫瘍活性増強剤

Info

Publication number
JPS62155215A
JPS62155215A JP60269171A JP26917185A JPS62155215A JP S62155215 A JPS62155215 A JP S62155215A JP 60269171 A JP60269171 A JP 60269171A JP 26917185 A JP26917185 A JP 26917185A JP S62155215 A JPS62155215 A JP S62155215A
Authority
JP
Japan
Prior art keywords
group
compound
nmr
yield
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP60269171A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0580451B2 (https=
Inventor
Setsuo Fujii
藤井　節郎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP60269171A priority Critical patent/JPS62155215A/ja
Publication of JPS62155215A publication Critical patent/JPS62155215A/ja
Publication of JPH0580451B2 publication Critical patent/JPH0580451B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP60269171A 1984-11-30 1985-11-27 抗腫瘍活性増強剤 Granted JPS62155215A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP60269171A JPS62155215A (ja) 1984-11-30 1985-11-27 抗腫瘍活性増強剤

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
JP25458784 1984-11-30
JP59-254587 1984-11-30
JP719085 1985-01-17
JP60-7190 1985-01-17
JP5978885 1985-03-25
JP60-59788 1985-03-25
JP60-192582 1985-08-30
JP19258285 1985-08-30
JP20789285 1985-09-19
JP60-207892 1985-09-19
JP60269171A JPS62155215A (ja) 1984-11-30 1985-11-27 抗腫瘍活性増強剤

Publications (2)

Publication Number Publication Date
JPS62155215A true JPS62155215A (ja) 1987-07-10
JPH0580451B2 JPH0580451B2 (https=) 1993-11-09

Family

ID=43447700

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60269171A Granted JPS62155215A (ja) 1984-11-30 1985-11-27 抗腫瘍活性増強剤

Country Status (1)

Country Link
JP (1) JPS62155215A (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021345A1 (en) * 1991-05-27 1992-12-10 Taiho Pharmaceutical Co., Ltd. Composition, method and kit for potentiating antitumor activity and for curing tumor
WO2006080339A1 (ja) * 2005-01-26 2006-08-03 Taiho Pharmaceutical Co., Ltd. ５－クロロ－２，４－ジヒドロキシピリジンの製造方法
WO2006106983A1 (ja) 2005-04-01 2006-10-12 Taiho Pharmaceutical Co., Ltd. 放射線治療増強剤

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021345A1 (en) * 1991-05-27 1992-12-10 Taiho Pharmaceutical Co., Ltd. Composition, method and kit for potentiating antitumor activity and for curing tumor
US5525603A (en) * 1991-05-27 1996-06-11 Taiho Pharmaceutical Co., Ltd. Compositions, methods and kits for potentiating antitumor effect and for treating tumor
JP2614164B2 (ja) * 1991-05-27 1997-05-28 大鵬薬品工業株式会社 抗腫瘍効果増強のための及び腫瘍治療のための組成物
WO2006080339A1 (ja) * 2005-01-26 2006-08-03 Taiho Pharmaceutical Co., Ltd. ５－クロロ－２，４－ジヒドロキシピリジンの製造方法
US7557216B2 (en) 2005-01-26 2009-07-07 Taiho Pharmaceutical Co., Ltd. Process for production of 5-chloro-2,4-dihydroxypyridine
JP4892472B2 (ja) * 2005-01-26 2012-03-07 大鵬薬品工業株式会社 ５−クロロ−２，４−ジヒドロキシピリジンの製造方法
KR101253367B1 (ko) * 2005-01-26 2013-04-11 다이호야쿠힌고교 가부시키가이샤 ５―클로로―２，４-디히드록시피리딘의 제조방법
WO2006106983A1 (ja) 2005-04-01 2006-10-12 Taiho Pharmaceutical Co., Ltd. 放射線治療増強剤

Also Published As

Publication number Publication date
JPH0580451B2 (https=) 1993-11-09

Similar Documents

Publication Publication Date Title
KR100589935B1 (ko) 신규한 피라진 유도체 또는 그 염, 및 이를 함유하는 의약 조성물
JP4202274B2 (ja) Ｎ４−アシル−５′−デオキシ−５−フルオロシチジン誘導体の新規製造法
Wigerinck et al. Synthesis and antiviral activity of 5-thien-2-yl-2'-deoxyuridine analogs
EP0180188B1 (en) A composition for increasing the anti-cancer activity of an anti-cancer compound
JP3229990B2 (ja) β―立体配置をもつジオキソランヌクレオシドの合成のための方法および成分
CN113621005A (zh) 半乳糖凝集素的α-D-半乳糖苷抑制剂
EP0323441B1 (en) 5-Fluorouracil derivatives
US5047521A (en) 5-fluorouracil derivatives
JPS62155215A (ja) 抗腫瘍活性増強剤
HK1003112B (en) 5-fluorouracil derivatives
Berber et al. Synthesis of some cyclic and acyclic nucleoside analogues derived from 4-(trifluoromethyl) pyrimidines
JPS62149696A (ja) ２′−デオキシ−５−フルオロウリジン誘導体
Jones et al. Synthesis of 5-(1-substituted ethyl) uracil derivatives and some of their chemical and biological properties
US5703224A (en) Antiviral c-nucleoside derivatives
JPH0446244B2 (https=)
JPS63301880A (ja) ５−フルオロウラシル誘導体
JPS61106593A (ja) ２′−デオキシ−５−フルオロウリジン誘導体
Enders et al. Asymmetric Synthesis of 4′-Quaternary 2′-Deoxy-3′-and-4′-epi-β-C-and-N-Nucleosides
JPH01199992A (ja) ２′−デオキシ−５−フルオロウリジン誘導体
US4689321A (en) Oxo propenyl nucleosides and nucleoside related analogs
JPH0665211A (ja) シクロペンタンヌクレオシド化合物
JPWO1995015964A1 (ja) ヌクレオシド誘導体
WO1990009999A1 (de) Seco-nucleosid-derivate und diese enthaltende arzneimittel
JPH10168096A (ja) ２’−アジド−２’−デオキシ−４’−チオリボヌクレオシド

Legal Events

Date Code Title Description
R153 Grant of patent term extension

Free format text: JAPANESE INTERMEDIATE CODE: R153

R153 Grant of patent term extension

Free format text: JAPANESE INTERMEDIATE CODE: R153

R153 Grant of patent term extension

Free format text: JAPANESE INTERMEDIATE CODE: R153

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20071109

Year of fee payment: 14

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20101109

Year of fee payment: 17

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20101109

Year of fee payment: 17

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20111109

Year of fee payment: 18

EXPY Cancellation because of completion of term
FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20111109

Year of fee payment: 18