JPS6136181B2 - - Google Patents
Info
- Publication number
- JPS6136181B2 JPS6136181B2 JP52071163A JP7116377A JPS6136181B2 JP S6136181 B2 JPS6136181 B2 JP S6136181B2 JP 52071163 A JP52071163 A JP 52071163A JP 7116377 A JP7116377 A JP 7116377A JP S6136181 B2 JPS6136181 B2 JP S6136181B2
- Authority
- JP
- Japan
- Prior art keywords
- test device
- supported
- reagent test
- substance
- carrier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000126 substance Substances 0.000 claims description 61
- 239000003153 chemical reaction reagent Substances 0.000 claims description 51
- 238000012360 testing method Methods 0.000 claims description 44
- 238000000034 method Methods 0.000 claims description 37
- 239000007788 liquid Substances 0.000 claims description 26
- 238000007639 printing Methods 0.000 claims description 22
- 239000000463 material Substances 0.000 claims description 10
- 238000004519 manufacturing process Methods 0.000 claims description 7
- 238000007641 inkjet printing Methods 0.000 claims description 3
- 238000007646 gravure printing Methods 0.000 claims description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 14
- 102000004190 Enzymes Human genes 0.000 description 10
- 108090000790 Enzymes Proteins 0.000 description 10
- 229940088598 enzyme Drugs 0.000 description 10
- 108010015776 Glucose oxidase Proteins 0.000 description 8
- 239000000203 mixture Substances 0.000 description 7
- 239000004366 Glucose oxidase Substances 0.000 description 6
- 102000003992 Peroxidases Human genes 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 6
- 229940116332 glucose oxidase Drugs 0.000 description 6
- 235000019420 glucose oxidase Nutrition 0.000 description 6
- 102000016938 Catalase Human genes 0.000 description 5
- 108010053835 Catalase Proteins 0.000 description 5
- OMOVVBIIQSXZSZ-UHFFFAOYSA-N [6-(4-acetyloxy-5,9a-dimethyl-2,7-dioxo-4,5a,6,9-tetrahydro-3h-pyrano[3,4-b]oxepin-5-yl)-5-formyloxy-3-(furan-3-yl)-3a-methyl-7-methylidene-1a,2,3,4,5,6-hexahydroindeno[1,7a-b]oxiren-4-yl] 2-hydroxy-3-methylpentanoate Chemical compound CC12C(OC(=O)C(O)C(C)CC)C(OC=O)C(C3(C)C(CC(=O)OC4(C)COC(=O)CC43)OC(C)=O)C(=C)C32OC3CC1C=1C=COC=1 OMOVVBIIQSXZSZ-UHFFFAOYSA-N 0.000 description 5
- NUIURNJTPRWVAP-UHFFFAOYSA-N 3,3'-Dimethylbenzidine Chemical compound C1=C(N)C(C)=CC(C=2C=C(C)C(N)=CC=2)=C1 NUIURNJTPRWVAP-UHFFFAOYSA-N 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 239000001913 cellulose Substances 0.000 description 3
- 229920002678 cellulose Polymers 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 108040007629 peroxidase activity proteins Proteins 0.000 description 3
- GZCGUPFRVQAUEE-VANKVMQKSA-N aldehydo-L-glucose Chemical compound OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)C=O GZCGUPFRVQAUEE-VANKVMQKSA-N 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 239000003094 microcapsule Substances 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 238000004445 quantitative analysis Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41M—PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES; COLOUR PRINTING
- B41M3/00—Printing processes to produce particular kinds of printed work, e.g. patterns
- B41M3/14—Security printing
- B41M3/142—Security printing using chemical colour-formers or chemical reactions, e.g. leuco-dye/acid, photochromes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41M—PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES; COLOUR PRINTING
- B41M3/00—Printing processes to produce particular kinds of printed work, e.g. patterns
- B41M3/001—Printing processes to produce particular kinds of printed work, e.g. patterns using chemical colour-formers or chemical reactions, e.g. leuco dyes or acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
- G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/521—Single-layer analytical elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00657—One-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7606999A SE423651B (sv) | 1976-06-18 | 1976-06-18 | Forfarande vid framstellning av en indikator av det slag som innefattar en berare och tva av denna uppburna substanser avsedda att aktiveras ner indikatorn skall anvendas |
| SE7613334A SE402822B (sv) | 1976-11-29 | 1976-11-29 | Indikator innefattande en berare och minst tva av denna uppburna substanser avsedda att aktiveras vid indikatorns anvendning |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5313485A JPS5313485A (en) | 1978-02-07 |
| JPS6136181B2 true JPS6136181B2 (fr) | 1986-08-16 |
Family
ID=26656724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7116377A Granted JPS5313485A (en) | 1976-06-18 | 1977-06-17 | Reagent tester and production method thereof |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5313485A (fr) |
| AR (1) | AR217076A1 (fr) |
| AU (1) | AU506896B2 (fr) |
| BR (1) | BR7703799A (fr) |
| CA (1) | CA1101771A (fr) |
| CH (1) | CH629306A5 (fr) |
| DD (1) | DD130280A5 (fr) |
| DE (1) | DE2727347A1 (fr) |
| DK (1) | DK269177A (fr) |
| ES (1) | ES459894A1 (fr) |
| FR (1) | FR2355290A1 (fr) |
| GB (1) | GB1526708A (fr) |
| HU (1) | HU176739B (fr) |
| IE (1) | IE44940B1 (fr) |
| IL (1) | IL52322A (fr) |
| IT (1) | IT1143673B (fr) |
| LU (1) | LU77564A1 (fr) |
| NL (1) | NL7706718A (fr) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5622871A (en) | 1987-04-27 | 1997-04-22 | Unilever Patent Holdings B.V. | Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents |
| US4046513A (en) * | 1976-06-30 | 1977-09-06 | Miles Laboratories, Inc. | Printed reagent test devices and method of making same |
| JPS568547A (en) * | 1979-07-03 | 1981-01-28 | Mitsubishi Gas Chem Co Inc | Printable detecting agent |
| SE427389B (sv) * | 1981-03-02 | 1983-03-28 | Alfa Laval Ab | Indikator innefattande en berare och ett reaktionssystem |
| EP0063810B1 (fr) * | 1981-04-29 | 1986-03-05 | Ciba-Geigy Ag | Dispositif et trousses pour les analyses immunologiques |
| JPS59137009U (ja) * | 1983-03-03 | 1984-09-12 | 豊田 襄 | コンクリ−トブロツク製造用中型 |
| JPS609610U (ja) * | 1983-06-30 | 1985-01-23 | 株式会社 アクツ | ボツクスカルバ−トの内型枠 |
| US4526753A (en) * | 1983-07-06 | 1985-07-02 | Miles Laboratories, Inc. | Multiple profile reagent card |
| JPH0653074B2 (ja) * | 1984-02-24 | 1994-07-20 | 大日本印刷株式会社 | 体液検査体 |
| JPS614959A (ja) * | 1984-06-19 | 1986-01-10 | Fuji Photo Film Co Ltd | 一体型多層分析要素 |
| JPS6278406U (fr) * | 1985-11-05 | 1987-05-19 | ||
| EP0226465B1 (fr) * | 1985-12-12 | 1993-03-10 | Fuji Photo Film Co., Ltd. | Elément analytique intégrant à plusieurs couches |
| DE3722273A1 (de) * | 1986-07-08 | 1988-01-21 | Bio Rad Laboratories | Festphasen-bindungsreagentien, ihre herstellung und sie enthaltende assay-kits |
| AU603617B2 (en) * | 1986-11-17 | 1990-11-22 | Abbott Laboratories | Apparatus and process for reagent fluid dispensing and printing |
| DE560410T1 (de) | 1987-04-27 | 2001-12-20 | Unilever Nv | Testgerät zur Durchführung von spezifischen Bindungsprüfungen. |
| GB8810400D0 (en) | 1988-05-03 | 1988-06-08 | Southern E | Analysing polynucleotide sequences |
| US7811751B2 (en) | 1988-05-03 | 2010-10-12 | Oxford Gene Technology Limited | Analysing polynucleotide sequences |
| US6352862B1 (en) | 1989-02-17 | 2002-03-05 | Unilever Patent Holdings B.V. | Analytical test device for imuno assays and methods of using same |
| DE4024544A1 (de) * | 1990-08-02 | 1992-02-06 | Boehringer Mannheim Gmbh | Analyseelement und verfahren zu seiner herstellung |
| DE4024545A1 (de) * | 1990-08-02 | 1992-02-06 | Boehringer Mannheim Gmbh | Verfahren und vorrichtung zum dosierten zufuehren einer biochemischen analysefluessigkeit auf ein target |
| DE4202850A1 (de) * | 1992-01-31 | 1993-08-05 | Boehringer Mannheim Gmbh | Analysenelement fuer immunoassays |
| DE4202848A1 (de) * | 1992-01-31 | 1993-08-05 | Boehringer Mannheim Gmbh | Analysenelement fuer immunoassays |
| DE19707204A1 (de) | 1997-02-24 | 1998-08-27 | Boehringer Mannheim Gmbh | System zur Herstellung diagnostischer Vielfach-Testelemente |
| US6004752A (en) * | 1997-07-29 | 1999-12-21 | Sarnoff Corporation | Solid support with attached molecules |
| US6830934B1 (en) | 1999-06-15 | 2004-12-14 | Lifescan, Inc. | Microdroplet dispensing for a medical diagnostic device |
| US6521182B1 (en) | 1998-07-20 | 2003-02-18 | Lifescan, Inc. | Fluidic device for medical diagnostics |
| JP2001186880A (ja) | 1999-10-22 | 2001-07-10 | Ngk Insulators Ltd | Ｄｎａチップの製造方法 |
| DE60207196T2 (de) | 2002-04-09 | 2006-07-20 | Cholestech Corp., Hayward | Verfahren und Vorrichtung zur Quantifizierung von Lipoprotein-Cholesterol hoher Dichte |
| DE102004029909A1 (de) | 2004-06-21 | 2006-01-19 | Roche Diagnostics Gmbh | Verfahren und Vorrichtung zur Herstellung von bindungsfähigen Reagenzträgern |
| US8343074B2 (en) | 2004-06-30 | 2013-01-01 | Lifescan Scotland Limited | Fluid handling devices |
| WO2008086019A1 (fr) | 2007-01-09 | 2008-07-17 | Cholestech Corporation | Dispositif et procédé de mesure du cholestérol associé au ldl |
| DE102009010563A1 (de) | 2009-02-16 | 2010-08-26 | Matthias W. Engel | Vorrichtung zum Nachweis von Analyten in Körperflüssigkeiten |
| US8486717B2 (en) | 2011-01-18 | 2013-07-16 | Symbolics, Llc | Lateral flow assays using two dimensional features |
| US9651549B2 (en) | 2012-07-13 | 2017-05-16 | Genisphere, Llc | Lateral flow assays using DNA dendrimers |
| US9874556B2 (en) | 2012-07-18 | 2018-01-23 | Symbolics, Llc | Lateral flow assays using two dimensional features |
| CN105102980B (zh) | 2013-02-26 | 2017-11-03 | 阿斯图特医药公司 | 具有试条保持件的横向流动测定法 |
| CN108051590B (zh) | 2013-09-13 | 2020-12-11 | Symbolics有限责任公司 | 运用二维试验和对照信号读出模式的侧向层析检测 |
| US20180106799A1 (en) | 2015-04-06 | 2018-04-19 | Bludiagnostics, Inc. | A test device for detecting an analyte in a saliva sample and method of use |
| WO2018039047A1 (fr) | 2016-08-23 | 2018-03-01 | Qoolabs, Inc. | Dosage à écoulement latéral pour évaluer l'expression de protéines recombinées ou l'expression de gènes reporters |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3666421A (en) * | 1971-04-05 | 1972-05-30 | Organon | Diagnostic test slide |
| CA1023251A (fr) * | 1973-06-22 | 1977-12-27 | The Standard Oil Company | Methode pour determiner les faibles teneurs en plomb des combustibles a base d'hydrocarbures, au moyen d'un ruban reactif en papier |
-
1977
- 1977-06-15 IL IL52322A patent/IL52322A/xx unknown
- 1977-06-16 DE DE19772727347 patent/DE2727347A1/de active Granted
- 1977-06-16 HU HU77AA869A patent/HU176739B/hu unknown
- 1977-06-17 GB GB25514/77A patent/GB1526708A/en not_active Expired
- 1977-06-17 JP JP7116377A patent/JPS5313485A/ja active Granted
- 1977-06-17 BR BR7703799A patent/BR7703799A/pt unknown
- 1977-06-17 CA CA280,848A patent/CA1101771A/fr not_active Expired
- 1977-06-17 IE IE1242/77A patent/IE44940B1/en unknown
- 1977-06-17 FR FR7718614A patent/FR2355290A1/fr active Granted
- 1977-06-17 IT IT24811/77A patent/IT1143673B/it active
- 1977-06-17 LU LU77564A patent/LU77564A1/xx unknown
- 1977-06-17 NL NL7706718A patent/NL7706718A/xx not_active Application Discontinuation
- 1977-06-17 ES ES459894A patent/ES459894A1/es not_active Expired
- 1977-06-17 DD DD7700199562A patent/DD130280A5/xx unknown
- 1977-06-17 DK DK269177A patent/DK269177A/da unknown
- 1977-06-17 CH CH749177A patent/CH629306A5/de not_active IP Right Cessation
- 1977-06-20 AU AU26223/77A patent/AU506896B2/en not_active Expired
- 1977-06-21 AR AR268136A patent/AR217076A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| DE2727347A1 (de) | 1977-12-22 |
| DK269177A (da) | 1977-12-19 |
| AU506896B2 (en) | 1980-01-24 |
| IE44940B1 (en) | 1982-05-19 |
| BR7703799A (pt) | 1978-04-18 |
| CA1101771A (fr) | 1981-05-26 |
| DD130280A5 (de) | 1978-03-15 |
| LU77564A1 (fr) | 1977-09-21 |
| CH629306A5 (en) | 1982-04-15 |
| IE44940L (en) | 1977-12-18 |
| GB1526708A (en) | 1978-09-27 |
| AU2622377A (en) | 1979-01-04 |
| NL7706718A (nl) | 1977-12-20 |
| AR217076A1 (es) | 1980-02-29 |
| DE2727347C2 (fr) | 1987-02-05 |
| FR2355290B1 (fr) | 1980-12-05 |
| JPS5313485A (en) | 1978-02-07 |
| IL52322A0 (en) | 1977-08-31 |
| IT1143673B (it) | 1986-10-22 |
| IL52322A (en) | 1980-10-26 |
| FR2355290A1 (fr) | 1978-01-13 |
| HU176739B (en) | 1981-05-28 |
| ES459894A1 (es) | 1978-10-01 |
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