JPS61134398A - 新生理活性物質プリパスタチン及びその製造法 - Google Patents

新生理活性物質プリパスタチン及びその製造法

Info

Publication number
JPS61134398A
JPS61134398A JP59256475A JP25647584A JPS61134398A JP S61134398 A JPS61134398 A JP S61134398A JP 59256475 A JP59256475 A JP 59256475A JP 25647584 A JP25647584 A JP 25647584A JP S61134398 A JPS61134398 A JP S61134398A
Authority
JP
Japan
Prior art keywords
plipastatin
culture
acid
production
prepastatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP59256475A
Other languages
English (en)
Japanese (ja)
Inventor
Hamao Umezawa
梅沢　浜夫
Takaaki Aoyanagi
青柳　高明
Tomio Takeuchi
富雄 竹内
Masa Hamada
雅 浜田
Hiroshi Osanawa
博 長縄
Yasuhiko Muraoka
靖彦 村岡
Takaaki Nishikiori
錦織　隆昭
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP59256475A priority Critical patent/JPS61134398A/ja
Priority to AU50307/85A priority patent/AU583553B2/en
Priority to EP85114935A priority patent/EP0192828B1/en
Priority to DE8585114935T priority patent/DE3582791D1/de
Priority to AT85114935T priority patent/ATE63318T1/de
Priority to US06/801,809 priority patent/US4742155A/en
Priority to GR852894A priority patent/GR852894B/el
Priority to ES549565A priority patent/ES8701197A1/es
Priority to KR1019850009104A priority patent/KR920006881B1/ko
Priority to HU854644A priority patent/HU193838B/hu
Priority to ZA859315A priority patent/ZA859315B/xx
Priority to DK564785A priority patent/DK564785A/da
Priority to PT81615A priority patent/PT81615B/pt
Publication of JPS61134398A publication Critical patent/JPS61134398A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus
    • C12R2001/085—Bacillus cereus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • External Artificial Organs (AREA)
JP59256475A 1984-12-06 1984-12-06 新生理活性物質プリパスタチン及びその製造法 Pending JPS61134398A (ja)

Priority Applications (13)

Application Number Priority Date Filing Date Title
JP59256475A JPS61134398A (ja) 1984-12-06 1984-12-06 新生理活性物質プリパスタチン及びその製造法
AU50307/85A AU583553B2 (en) 1984-12-06 1985-11-25 Plipastatin and method for preparation thereof
EP85114935A EP0192828B1 (en) 1984-12-06 1985-11-26 Novel, immunosuppressive compounds, a microbiological method for their preparation and their use as medicaments
DE8585114935T DE3582791D1 (de) 1984-12-06 1985-11-26 Immunosuppressive verbindungen, deren mikrobiologische verfahren zur herstellung und deren verwendung als arzneimittel.
AT85114935T ATE63318T1 (de) 1984-12-06 1985-11-26 Immunosuppressive verbindungen, deren mikrobiologische verfahren zur herstellung und deren verwendung als arzneimittel.
US06/801,809 US4742155A (en) 1984-12-06 1985-11-26 Plipastatin and method for preparation thereof
GR852894A GR852894B (enExample) 1984-12-06 1985-12-02
ES549565A ES8701197A1 (es) 1984-12-06 1985-12-04 Un procedimiento para preparar plipastatina
KR1019850009104A KR920006881B1 (ko) 1984-12-06 1985-12-04 프리파스타틴(plipastatin)의 제조방법
HU854644A HU193838B (en) 1984-12-06 1985-12-04 Microbial process for producing new, physiologically active compounds
ZA859315A ZA859315B (en) 1984-12-06 1985-12-05 Novel,immunosuppressive compounds,a microbiological method for their preparation and their use as medicaments
DK564785A DK564785A (da) 1984-12-06 1985-12-05 Plipastatin, dets fremstilling og anvendelse, samt en ved fremstillingen anvendelig mikroorganisme
PT81615A PT81615B (pt) 1984-12-06 1985-12-05 Processo microbiologico para a preparacao de compostos imunossupressivos e de composicoes farmaceuticas que os contem

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59256475A JPS61134398A (ja) 1984-12-06 1984-12-06 新生理活性物質プリパスタチン及びその製造法

Publications (1)

Publication Number Publication Date
JPS61134398A true JPS61134398A (ja) 1986-06-21

Family

ID=17293148

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59256475A Pending JPS61134398A (ja) 1984-12-06 1984-12-06 新生理活性物質プリパスタチン及びその製造法

Country Status (13)

Country Link
US (1) US4742155A (enExample)
EP (1) EP0192828B1 (enExample)
JP (1) JPS61134398A (enExample)
KR (1) KR920006881B1 (enExample)
AT (1) ATE63318T1 (enExample)
AU (1) AU583553B2 (enExample)
DE (1) DE3582791D1 (enExample)
DK (1) DK564785A (enExample)
ES (1) ES8701197A1 (enExample)
GR (1) GR852894B (enExample)
HU (1) HU193838B (enExample)
PT (1) PT81615B (enExample)
ZA (1) ZA859315B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5217952A (en) * 1988-02-02 1993-06-08 Fujisawa Pharmaceutical Co., Ltd. Peptides WS-9326a and WS-9326b, derivatives thereof and uses thereof
US5436140A (en) * 1988-02-02 1995-07-25 Fujisawa Pharmaceutical Co., Ltd. Process for producing WS-9326A and WS-9326B
IN167138B (enExample) * 1988-08-17 1990-09-01 Hoechst India
US5619066A (en) * 1990-05-15 1997-04-08 Dallas Semiconductor Corporation Memory for an electronic token
DE69229173T2 (de) * 1991-07-04 1999-09-16 Garvan Institute Of Medical Research, Darlinghurst Pla2 hemmende verbindungen
PL198772B1 (pl) * 1997-05-09 2008-07-31 Agraquest Biologicznie czysta kultura Bacillus subtilis, jej metabolit i supernatant z hodowli szczepu, kompozycje do ochrony roślin i owoców przed szkodnikami, sposób ochrony lub leczenia roślin i owoców, agrastatyny, sposób izolowania supernatantu o aktywności owadobójczej
CN117683074B (zh) * 2023-12-13 2024-08-16 山东绿邦生物科技有限公司 蜡样芽孢杆菌、蛋白酶抑制剂以及提高蛋白渣产量的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201771A (en) * 1979-03-12 1980-05-06 Merck & Co., Inc. Antibiotic A43F

Also Published As

Publication number Publication date
ZA859315B (en) 1986-10-29
ES8701197A1 (es) 1986-11-16
HUT40707A (en) 1987-01-28
US4742155A (en) 1988-05-03
EP0192828B1 (en) 1991-05-08
KR860005027A (ko) 1986-07-16
EP0192828A3 (en) 1988-06-01
EP0192828A2 (en) 1986-09-03
KR920006881B1 (ko) 1992-08-21
GR852894B (enExample) 1986-04-01
ES549565A0 (es) 1986-11-16
HU193838B (en) 1987-12-28
DK564785A (da) 1986-06-07
PT81615B (pt) 1988-02-17
AU583553B2 (en) 1989-05-04
DK564785D0 (da) 1985-12-05
ATE63318T1 (de) 1991-05-15
PT81615A (en) 1986-01-01
DE3582791D1 (de) 1991-06-13
AU5030785A (en) 1986-06-12

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