DE69229173T2 - Pla2 hemmende verbindungen - Google Patents

Pla2 hemmende verbindungen

Info

Publication number
DE69229173T2
DE69229173T2 DE69229173T DE69229173T DE69229173T2 DE 69229173 T2 DE69229173 T2 DE 69229173T2 DE 69229173 T DE69229173 T DE 69229173T DE 69229173 T DE69229173 T DE 69229173T DE 69229173 T2 DE69229173 T2 DE 69229173T2
Authority
DE
Germany
Prior art keywords
inhibitive
pla2
connections
pla2 inhibitive
inhibitive connections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69229173T
Other languages
English (en)
Other versions
DE69229173D1 (de
Inventor
Albert Tseng
Adam Inglis
Kieran Francis Scott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scott Kieran Frances Waverley New South Wales
Original Assignee
Garvan Institute of Medical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Garvan Institute of Medical Research filed Critical Garvan Institute of Medical Research
Application granted granted Critical
Publication of DE69229173D1 publication Critical patent/DE69229173D1/de
Publication of DE69229173T2 publication Critical patent/DE69229173T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69229173T 1991-07-04 1992-07-06 Pla2 hemmende verbindungen Expired - Lifetime DE69229173T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPK705891 1991-07-04
PCT/AU1992/000333 WO1993001215A1 (en) 1991-07-04 1992-07-06 Pla2 inhibitory compounds

Publications (2)

Publication Number Publication Date
DE69229173D1 DE69229173D1 (de) 1999-06-17
DE69229173T2 true DE69229173T2 (de) 1999-09-16

Family

ID=3775525

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69229173T Expired - Lifetime DE69229173T2 (de) 1991-07-04 1992-07-06 Pla2 hemmende verbindungen

Country Status (5)

Country Link
US (1) US5656602A (de)
EP (1) EP0592553B1 (de)
JP (1) JPH07500814A (de)
DE (1) DE69229173T2 (de)
WO (1) WO1993001215A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998013376A1 (en) * 1996-09-27 1998-04-02 Garvan Institute Of Medical Research Inhibitors of pla¿2?
WO1998055504A1 (en) * 1997-06-05 1998-12-10 Institut Pasteur HsPLA2 GR II PEPTIDES EXHIBITING AN ANTICOAGULANT EFFECT
WO2000028997A1 (en) * 1998-11-12 2000-05-25 Analytica Ltd Phospholipase inhibitors for the treatment of cancer
CA2385406A1 (en) * 1999-09-21 2001-03-29 Shionogi & Co., Ltd. Gene encoding novel human secretory phospholipase a2
AU2003237397A1 (en) * 2002-06-04 2003-12-19 Sequenom, Inc. Diagnosing predisposition to fat deposition and therapeutic methods for reducing fat deposition and treatment of associated conditions
AUPS282602A0 (en) * 2002-06-07 2002-06-27 Garvan Institute Of Medical Research Method of inhibiting cell proliferation
CA2490367A1 (en) * 2002-06-27 2004-01-08 Sequenom, Inc. Therapeutic methods for reducing fat deposition and treating associated conditions
FI20105629A0 (fi) * 2010-06-03 2010-06-03 Estaja Oy Menetelmä lipidiaktivoituvien entsyymien peptidi-inhibiittoreiden valmistamiseksi ja menetelmällä valmistettuja peptidejä

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61134398A (ja) * 1984-12-06 1986-06-21 Microbial Chem Res Found 新生理活性物質プリパスタチン及びその製造法
US4792555A (en) * 1987-03-20 1988-12-20 American Home Products Corporation Phospholipase A2 inhibitors
EP0288965A2 (de) * 1987-04-29 1988-11-02 Hoechst Aktiengesellschaft Peptide mit Phospholipase A2- hemmender Wirkung
US5266562A (en) * 1987-11-19 1993-11-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Anti-inflammatory agents
JPH01199995A (ja) * 1988-02-04 1989-08-11 Kyowa Hakko Kogyo Co Ltd ホスホリパーゼａ↓２阻害ペプチド

Also Published As

Publication number Publication date
EP0592553A1 (de) 1994-04-20
EP0592553A4 (de) 1995-05-24
US5656602A (en) 1997-08-12
DE69229173D1 (de) 1999-06-17
EP0592553B1 (de) 1999-05-12
WO1993001215A1 (en) 1993-01-21
JPH07500814A (ja) 1995-01-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SCOTT, KIERAN FRANCES, WAVERLEY, NEW SOUTH WALES,