JPS6112631A - 免疫グロブリンｇ分子のプロテインａへの結合方法 - Google Patents

免疫グロブリンｇ分子のプロテインａへの結合方法

Info

Publication number
JPS6112631A
JPS6112631A JP60135808A JP13580885A JPS6112631A JP S6112631 A JPS6112631 A JP S6112631A JP 60135808 A JP60135808 A JP 60135808A JP 13580885 A JP13580885 A JP 13580885A JP S6112631 A JPS6112631 A JP S6112631A
Authority
JP
Japan
Prior art keywords
protein
immunoglobulin
molar
buffer
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP60135808A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0455440B2 (esLanguage
Inventor
ヘクター　ジョオレツ‐サリナス
ゲイリー　スティーブン　オット
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Rad Laboratories Inc
Original Assignee
Bio Rad Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24499435&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPS6112631(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bio Rad Laboratories Inc filed Critical Bio Rad Laboratories Inc
Publication of JPS6112631A publication Critical patent/JPS6112631A/ja
Publication of JPH0455440B2 publication Critical patent/JPH0455440B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/828—Protein A
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP60135808A 1984-06-22 1985-06-21 免疫グロブリンｇ分子のプロテインａへの結合方法 Granted JPS6112631A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/623,797 US4704366A (en) 1984-06-22 1984-06-22 Process for binding IgG to protein A
US623797 1984-06-22

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP3109760A Division JPH04234899A (ja) 1984-06-22 1991-04-15 免疫グロブリンｇ分子の単離方法

Publications (2)

Publication Number Publication Date
JPS6112631A true JPS6112631A (ja) 1986-01-21
JPH0455440B2 JPH0455440B2 (esLanguage) 1992-09-03

Family

ID=24499435

Family Applications (2)

Application Number Title Priority Date Filing Date
JP60135808A Granted JPS6112631A (ja) 1984-06-22 1985-06-21 免疫グロブリンｇ分子のプロテインａへの結合方法
JP3109760A Granted JPH04234899A (ja) 1984-06-22 1991-04-15 免疫グロブリンｇ分子の単離方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP3109760A Granted JPH04234899A (ja) 1984-06-22 1991-04-15 免疫グロブリンｇ分子の単離方法

Country Status (4)

Country Link
US (1) US4704366A (esLanguage)
JP (2) JPS6112631A (esLanguage)
DE (1) DE3521679A1 (esLanguage)
GB (1) GB2160530B (esLanguage)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4783872B2 (ja) * 2009-11-25 2011-09-28 パナソニック株式会社 免疫測定方法

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US4977247A (en) * 1986-02-14 1990-12-11 Genex Corporation Immobilized protein G variants and the use thereof
SE459662B (sv) * 1986-03-21 1989-07-24 Pharmacia Ab Hybrid-dna-molekyl som kodar foer ett protein med samma igg specificitet som protein g, plasmid innehaallande densamma samt foerfarande foer framstaellning av proteinet
US5089605A (en) * 1987-03-13 1992-02-18 Repligen Corporation Immobilized immunoglobulin-binding proteins
JPS6419024A (en) * 1987-07-15 1989-01-23 Tosoh Corp Separation of immunoglobulin g subclass
US4981961A (en) * 1988-09-12 1991-01-01 Bioprobe International, Inc. Synthetic affinity ligand compositions and methods for purification and recovery of organic molecules
US4933435A (en) * 1989-04-05 1990-06-12 Bioprobe International Antibody purification process
US5151504A (en) * 1989-11-17 1992-09-29 E. R. Squibb & Sons, Inc. Method for purification of monoclonal antibodies
US5077391A (en) * 1989-12-01 1991-12-31 Raison Robert L Purification of immunoglobulin M
JPH03185000A (ja) * 1989-12-15 1991-08-12 Tosoh Corp プロテインＡと免疫グロブリンＧ（ＩｇＧ）との結合方法
US5200471A (en) * 1990-11-05 1993-04-06 Minnesota Mining And Manufacturing Company Biomolecules covalently immobilized with a high bound specific biological activity and method of preparing same
US5245016A (en) * 1991-01-31 1993-09-14 University Of Utah Research Foundation Pseudomonas maltophilia immunoglobulin binding protein and methods for its use
JP3607289B2 (ja) * 1993-03-29 2005-01-05 ミネソタ マイニング アンド マニュファクチャリング カンパニー 多孔質支持体（ｐ．ｅ．アズラクトン）の内部にリガンドをカップリングする方法及びその使用法
US5593822A (en) * 1993-12-07 1997-01-14 John Wayne Cancer Institute IgG depleted serum preparations and methods for antibody production
US5561045A (en) * 1994-01-04 1996-10-01 Intracel Corporation Detection reagent, article, and immunoassay method
WO1995026977A1 (en) * 1994-04-01 1995-10-12 Unisyn Technologies, Inc. High salt binding buffer for immunoglobulin purification with a synthetic affinity ligand
BR0316670A (pt) * 2002-11-26 2005-10-11 Protein Design Labs Inc Anticorpos quiméricos e humanizados para integrina (alfa)5ß1 que modulam a angiogênese
US7276589B2 (en) * 2002-11-26 2007-10-02 Pdl Biopharma, Inc. Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis
US7285268B2 (en) * 2002-11-26 2007-10-23 Pdl Biopharma, Inc. Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis
US7662384B2 (en) * 2004-03-24 2010-02-16 Facet Biotech Corporation Use of anti-α5β1 antibodies to inhibit cancer cell proliferation
KR20100040877A (ko) * 2007-07-27 2010-04-21 패시트 바이오테크 코포레이션 티로신 키나제 억제제, 및 인테그린 알파1베타5(ｃｄ49ｅ)에 대한 항체를 포함하는 약학 조합물
US20100158893A1 (en) * 2008-12-19 2010-06-24 Baxter International Inc. Systems and methods for obtaining immunoglobulin from blood
DK3272764T3 (da) 2009-12-18 2024-05-06 Novartis Ag Fremgangsmåde til affinitetskromatografi
WO2012149197A2 (en) 2011-04-27 2012-11-01 Abbott Laboratories Methods for controlling the galactosylation profile of recombinantly-expressed proteins
KR102065387B1 (ko) 2011-11-21 2020-01-13 아박시스, 인크. 측방 유동 및 관련된 면역검정에서의 신호 증폭
US9150645B2 (en) 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
TW201348247A (zh) * 2012-05-21 2013-12-01 Abbvie Inc 利用蛋白質ａ親和性層析之非人類抗體之新穎純化
WO2013176754A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Novel purification of antibodies using hydrophobic interaction chromatography
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
HK1211981A1 (en) 2012-09-02 2016-06-03 Abbvie Inc. Methods to control protein heterogeneity
SG11201507230PA (en) 2013-03-12 2015-10-29 Abbvie Inc Human antibodies that bind human tnf-alpha and methods of preparing the same
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
US8921526B2 (en) 2013-03-14 2014-12-30 Abbvie, Inc. Mutated anti-TNFα antibodies and methods of their use
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
US11566082B2 (en) 2014-11-17 2023-01-31 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
WO2017024163A1 (en) 2015-08-04 2017-02-09 Abaxis, Inc. Signal amplification in solution-based plasmonic specific-binding partner assays
EP3455243B1 (en) 2016-05-11 2021-03-24 Cytiva BioProcess R&D AB Separation matrix
US10889615B2 (en) 2016-05-11 2021-01-12 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
EP3455241B1 (en) 2016-05-11 2022-02-23 Cytiva BioProcess R&D AB Method of cleaning and/or sanitizing a separation matrix
US10730908B2 (en) 2016-05-11 2020-08-04 Ge Healthcare Bioprocess R&D Ab Separation method
US10654887B2 (en) 2016-05-11 2020-05-19 Ge Healthcare Bio-Process R&D Ab Separation matrix
JP7106187B2 (ja) 2016-05-11 2022-07-26 サイティバ・バイオプロセス・アールアンドディ・アクチボラグ 分離マトリックスを保存する方法
JP7031934B2 (ja) 2016-05-11 2022-03-08 サイティバ・バイオプロセス・アールアンドディ・アクチボラグ 分離マトリックス
US10703774B2 (en) 2016-09-30 2020-07-07 Ge Healthcare Bioprocess R&D Ab Separation method
US12448411B2 (en) 2016-09-30 2025-10-21 Cytiva Bioprocess R&D Ab Separation method
EP3574308A4 (en) 2017-01-30 2020-12-30 Abaxis, Inc. PLASMONIC ASSAYS IN SOLUTION OF SPECIFIC BINDING PARTNERS, AND METAL NANOSTRUCTURES
CN111902720B (zh) 2018-03-21 2025-02-07 沃特世科技公司 基于非抗体高亲和力的样品制备、吸附剂、装置和方法

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SE413986B (sv) * 1973-03-23 1980-07-07 Exploaterings Ab Tbf Sett att separera amfipatiska emnen innehallande bade hydrofila och hydrofoba grupper samt gelprodukt for genomforande av separationen
US4430318A (en) * 1978-11-29 1984-02-07 The United States Of America As Represented By The Department Of Health And Human Services Immunoassay utilizing 125 I Protein A
US4230685A (en) * 1979-02-28 1980-10-28 Northwestern University Method of magnetic separation of cells and the like, and microspheres for use therein
AU570911B2 (en) * 1981-11-06 1988-03-31 Baylor College Of Medicine Immunoadsorbent based on immobilized protein a and its use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4783872B2 (ja) * 2009-11-25 2011-09-28 パナソニック株式会社 免疫測定方法

Also Published As

Publication number Publication date
US4704366A (en) 1987-11-03
GB2160530B (en) 1987-10-28
JPH0455440B2 (esLanguage) 1992-09-03
GB2160530A (en) 1985-12-24
GB8515261D0 (en) 1985-07-17
JPH0543719B2 (esLanguage) 1993-07-02
JPH04234899A (ja) 1992-08-24
DE3521679A1 (de) 1986-01-02
DE3521679C2 (esLanguage) 1989-08-24

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