JPS6080764A - 微小粒子を識別する方法及びその装置 - Google Patents
微小粒子を識別する方法及びその装置Info
- Publication number
- JPS6080764A JPS6080764A JP58189162A JP18916283A JPS6080764A JP S6080764 A JPS6080764 A JP S6080764A JP 58189162 A JP58189162 A JP 58189162A JP 18916283 A JP18916283 A JP 18916283A JP S6080764 A JPS6080764 A JP S6080764A
- Authority
- JP
- Japan
- Prior art keywords
- light
- cell
- microparticles
- particle stream
- irradiation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000011859 microparticle Substances 0.000 title claims abstract description 44
- 238000000034 method Methods 0.000 title claims description 43
- 230000008859 change Effects 0.000 claims abstract description 25
- 239000002245 particle Substances 0.000 claims description 54
- 230000002123 temporal effect Effects 0.000 claims description 14
- 239000000725 suspension Substances 0.000 claims description 10
- 230000001678 irradiating effect Effects 0.000 claims description 5
- 238000004020 luminiscence type Methods 0.000 claims description 5
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- 238000004611 spectroscopical analysis Methods 0.000 claims 1
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- 239000010419 fine particle Substances 0.000 description 2
- 238000000684 flow cytometry Methods 0.000 description 2
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- 102000039446 nucleic acids Human genes 0.000 description 2
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- 102000004169 proteins and genes Human genes 0.000 description 2
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- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 101000860173 Myxococcus xanthus C-factor Proteins 0.000 description 1
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- 108091005461 Nucleic proteins Proteins 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
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- VYXSBFYARXAAKO-WTKGSRSZSA-N chembl402140 Chemical compound Cl.C1=2C=C(C)C(NCC)=CC=2OC2=C\C(=N/CC)C(C)=CC2=C1C1=CC=CC=C1C(=O)OCC VYXSBFYARXAAKO-WTKGSRSZSA-N 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
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- 239000007789 gas Substances 0.000 description 1
- 230000007274 generation of a signal involved in cell-cell signaling Effects 0.000 description 1
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- 230000003834 intracellular effect Effects 0.000 description 1
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- 239000013307 optical fiber Substances 0.000 description 1
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- 108090000623 proteins and genes Proteins 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58189162A JPS6080764A (ja) | 1983-10-12 | 1983-10-12 | 微小粒子を識別する方法及びその装置 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58189162A JPS6080764A (ja) | 1983-10-12 | 1983-10-12 | 微小粒子を識別する方法及びその装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6080764A true JPS6080764A (ja) | 1985-05-08 |
| JPH0367224B2 JPH0367224B2 (enrdf_load_stackoverflow) | 1991-10-22 |
Family
ID=16236491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58189162A Granted JPS6080764A (ja) | 1983-10-12 | 1983-10-12 | 微小粒子を識別する方法及びその装置 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6080764A (enrdf_load_stackoverflow) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6135331A (ja) * | 1984-07-28 | 1986-02-19 | Japan Spectroscopic Co | 微小粒子分離装置 |
| JPS6394156A (ja) * | 1986-10-07 | 1988-04-25 | Toa Medical Electronics Co Ltd | 流体中の細胞分析装置 |
| JPH01209343A (ja) * | 1988-02-16 | 1989-08-23 | Shimadzu Corp | 分光蛍光光度計 |
| JP2006275858A (ja) * | 2005-03-30 | 2006-10-12 | National Institute Of Advanced Industrial & Technology | 蛍光検出方法、蛍光検出用ビーズの作製方法及び蛍光検出用ビーズ |
| JP2006284231A (ja) * | 2005-03-31 | 2006-10-19 | National Institute Of Advanced Industrial & Technology | 遺伝子断片中のヌクレオチドの種類の特定方法 |
| JP2014196987A (ja) * | 2013-03-29 | 2014-10-16 | シスメックス株式会社 | 細胞分析装置、細胞回収装置、細胞測定装置の管理方法およびコンピュータプログラム |
| JP2017535764A (ja) * | 2014-10-09 | 2017-11-30 | キネティック リバー コーポレーション | 粒子分析選別装置及び方法 |
| JP2018017700A (ja) * | 2016-07-29 | 2018-02-01 | 株式会社リコー | 粒子計数装置及び粒子計数方法、並びに液滴形成装置、及び分注装置 |
| JP2018096789A (ja) * | 2016-12-12 | 2018-06-21 | 株式会社リコー | 液滴形成装置、液滴形成方法、及び分注装置 |
| US10564088B2 (en) | 2014-10-09 | 2020-02-18 | Kinetic River Corp. | Particle analysis and sorting apparatus and methods |
| US10732087B2 (en) | 2016-01-26 | 2020-08-04 | Ricoh Company, Ltd. | Liquid droplet forming device, dispensing device, and method of preparing base material |
| US11740174B2 (en) | 2014-10-09 | 2023-08-29 | Kinetic River Corp. | Apparatus and methods for particle analysis and autofluorescence discrimination |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4874292A (enrdf_load_stackoverflow) * | 1971-12-23 | 1973-10-06 | ||
| JPS5190868A (enrdf_load_stackoverflow) * | 1975-02-06 | 1976-08-09 | ||
| JPS5633052A (en) * | 1979-08-20 | 1981-04-03 | Ortho Diagnostics | Electrostatic grain selecting method and its mechanism |
| JPS57194354A (en) * | 1981-05-26 | 1982-11-29 | Fujitsu Ltd | Analytical separation apparatus of multistage type living body cell |
| JPS57211557A (en) * | 1981-06-24 | 1982-12-25 | Fujitsu Ltd | Cell sorter |
| JPS6445018A (en) * | 1987-08-13 | 1989-02-17 | Univ Tokai | Manufacture of superconductive material |
-
1983
- 1983-10-12 JP JP58189162A patent/JPS6080764A/ja active Granted
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4874292A (enrdf_load_stackoverflow) * | 1971-12-23 | 1973-10-06 | ||
| JPS5190868A (enrdf_load_stackoverflow) * | 1975-02-06 | 1976-08-09 | ||
| JPS5633052A (en) * | 1979-08-20 | 1981-04-03 | Ortho Diagnostics | Electrostatic grain selecting method and its mechanism |
| JPS57194354A (en) * | 1981-05-26 | 1982-11-29 | Fujitsu Ltd | Analytical separation apparatus of multistage type living body cell |
| JPS57211557A (en) * | 1981-06-24 | 1982-12-25 | Fujitsu Ltd | Cell sorter |
| JPS6445018A (en) * | 1987-08-13 | 1989-02-17 | Univ Tokai | Manufacture of superconductive material |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6135331A (ja) * | 1984-07-28 | 1986-02-19 | Japan Spectroscopic Co | 微小粒子分離装置 |
| JPS6394156A (ja) * | 1986-10-07 | 1988-04-25 | Toa Medical Electronics Co Ltd | 流体中の細胞分析装置 |
| JPH01209343A (ja) * | 1988-02-16 | 1989-08-23 | Shimadzu Corp | 分光蛍光光度計 |
| JP2006275858A (ja) * | 2005-03-30 | 2006-10-12 | National Institute Of Advanced Industrial & Technology | 蛍光検出方法、蛍光検出用ビーズの作製方法及び蛍光検出用ビーズ |
| JP2006284231A (ja) * | 2005-03-31 | 2006-10-19 | National Institute Of Advanced Industrial & Technology | 遺伝子断片中のヌクレオチドの種類の特定方法 |
| JP2014196987A (ja) * | 2013-03-29 | 2014-10-16 | シスメックス株式会社 | 細胞分析装置、細胞回収装置、細胞測定装置の管理方法およびコンピュータプログラム |
| JP2017535764A (ja) * | 2014-10-09 | 2017-11-30 | キネティック リバー コーポレーション | 粒子分析選別装置及び方法 |
| US10564088B2 (en) | 2014-10-09 | 2020-02-18 | Kinetic River Corp. | Particle analysis and sorting apparatus and methods |
| US10955330B2 (en) | 2014-10-09 | 2021-03-23 | Kinetic River Corp. | Particle analysis and sorting apparatus and methods |
| US11740174B2 (en) | 2014-10-09 | 2023-08-29 | Kinetic River Corp. | Apparatus and methods for particle analysis and autofluorescence discrimination |
| US10732087B2 (en) | 2016-01-26 | 2020-08-04 | Ricoh Company, Ltd. | Liquid droplet forming device, dispensing device, and method of preparing base material |
| JP2018017700A (ja) * | 2016-07-29 | 2018-02-01 | 株式会社リコー | 粒子計数装置及び粒子計数方法、並びに液滴形成装置、及び分注装置 |
| JP2018096789A (ja) * | 2016-12-12 | 2018-06-21 | 株式会社リコー | 液滴形成装置、液滴形成方法、及び分注装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0367224B2 (enrdf_load_stackoverflow) | 1991-10-22 |
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