JPS6045845B2 - 医薬物質含有マイクロカプセルの製法 - Google Patents

医薬物質含有マイクロカプセルの製法

Info

Publication number
JPS6045845B2
JPS6045845B2 JP54141826A JP14182679A JPS6045845B2 JP S6045845 B2 JPS6045845 B2 JP S6045845B2 JP 54141826 A JP54141826 A JP 54141826A JP 14182679 A JP14182679 A JP 14182679A JP S6045845 B2 JPS6045845 B2 JP S6045845B2
Authority
JP
Japan
Prior art keywords
microcapsules
phospholipid
cyclohexane
ethylcellulose
phase separation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP54141826A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5665821A (en
Inventor
政義 鮫島
五一 平田
義之 鯉田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Priority to JP54141826A priority Critical patent/JPS6045845B2/ja
Priority to US06/194,809 priority patent/US4389331A/en
Priority to DE19803039908 priority patent/DE3039908A1/de
Priority to FR8023109A priority patent/FR2468364A1/fr
Priority to CH8075/80A priority patent/CH647675A5/de
Priority to IT25676/80A priority patent/IT1134115B/it
Priority to GB8034872A priority patent/GB2061866B/en
Publication of JPS5665821A publication Critical patent/JPS5665821A/ja
Publication of JPS6045845B2 publication Critical patent/JPS6045845B2/ja
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
JP54141826A 1979-10-31 1979-10-31 医薬物質含有マイクロカプセルの製法 Expired JPS6045845B2 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP54141826A JPS6045845B2 (ja) 1979-10-31 1979-10-31 医薬物質含有マイクロカプセルの製法
US06/194,809 US4389331A (en) 1979-10-31 1980-10-07 Process for preparing pharmaceutically active compound-containing microcapsules
DE19803039908 DE3039908A1 (de) 1979-10-31 1980-10-22 Verfahren zur herstellung von pharmazeutisch aktive verbindungen enthaltenden mikrokapseln
FR8023109A FR2468364A1 (fr) 1979-10-31 1980-10-29 Procede de preparation de microcapsules d'ethylcellulose contenant un compose pharmaceutiquement actif
CH8075/80A CH647675A5 (de) 1979-10-31 1980-10-30 Verfahren zur herstellung von pharmazeutisch aktive verbindungen enthaltenden mikrokapseln.
IT25676/80A IT1134115B (it) 1979-10-31 1980-10-30 Procedimento per preparare microcapsule contenenti composti attivi dal punto di vista farmaceutico
GB8034872A GB2061866B (en) 1979-10-31 1980-10-30 Process for preparing pharmaceutically active compound-containing microcapsules

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54141826A JPS6045845B2 (ja) 1979-10-31 1979-10-31 医薬物質含有マイクロカプセルの製法

Publications (2)

Publication Number Publication Date
JPS5665821A JPS5665821A (en) 1981-06-03
JPS6045845B2 true JPS6045845B2 (ja) 1985-10-12

Family

ID=15301018

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54141826A Expired JPS6045845B2 (ja) 1979-10-31 1979-10-31 医薬物質含有マイクロカプセルの製法

Country Status (7)

Country Link
US (1) US4389331A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS6045845B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH647675A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3039908A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2468364A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2061866B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1134115B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57197214A (en) * 1981-05-29 1982-12-03 Tanabe Seiyaku Co Ltd Rapid-releasing microcapsule and its preparation
JPS5916821A (ja) * 1982-07-16 1984-01-28 Tanabe Seiyaku Co Ltd 非凝集性マイクロカプセルの製法
US5290752A (en) * 1984-03-16 1994-03-01 Unitika Ltd. Method for preparation of a shaped chitin body containing a physiologically active substance
US4914084A (en) * 1984-05-09 1990-04-03 Synthetic Blood Corporation Composition and method for introducing heme, hemoproteins, and/or heme-hemoprotein complexes into the body
WO1989003678A1 (en) * 1987-10-30 1989-05-05 Stolle Research & Development Corporation Low residual solvent microspheres and microencapsulation process
US4996047A (en) * 1988-11-02 1991-02-26 Richardson-Vicks, Inc. Sustained release drug-resin complexes
HU201869B (en) * 1988-12-30 1991-01-28 Egyt Gyogyszervegyeszeti Gyar Process for producing microcapsules of quick dissolving active component
US5422122A (en) * 1992-08-04 1995-06-06 Eurand America, Incorporated Controlled release potassium chloride tablet
FR2752162B1 (fr) * 1996-08-07 1998-11-06 Jouveinal Lab Comprime de maleate de trimebutine pellicule
CN1233954A (zh) * 1996-10-01 1999-11-03 西马实验室股份有限公司 掩盖味道的微胶囊组合物及其制备方法
KR100483243B1 (ko) * 1998-03-02 2005-04-15 다이요 가가꾸 가부시끼가이샤 분말 조성물
US20030180368A1 (en) * 1998-03-14 2003-09-25 Cenes Drug Delivery Limited Production of microparticles
US9561182B2 (en) * 2003-08-22 2017-02-07 Cure Pharmaceutical Corporation Edible films for administration of medicaments to animals, methods for their manufacture and methods for their use for the treatment of animals
US8999372B2 (en) * 2002-11-14 2015-04-07 Cure Pharmaceutical Corporation Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use
US20040131662A1 (en) 2003-11-12 2004-07-08 Davidson Robert S. Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
US20040191302A1 (en) 2003-03-28 2004-09-30 Davidson Robert S. Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
CN104693269A (zh) * 2006-10-16 2015-06-10 协和发酵生化株式会社 谷胱甘肽的结晶及其制造方法
CA2708152A1 (en) * 2007-12-10 2009-06-18 Eurand, Inc Orally disintegrating tablets comprising diphenhydramine
WO2017172590A1 (en) * 2016-03-30 2017-10-05 Dow Global Technologies Llc Method of making oleogel

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3242051A (en) * 1958-12-22 1966-03-22 Ncr Co Coating by phase separation
US3155590A (en) * 1962-08-02 1964-11-03 Ncr Co Encapsulation process and its product
GB1147210A (en) * 1965-06-30 1969-04-02 Eastman Kodak Co Improvements in or relating to vitamins
US3531418A (en) * 1965-08-18 1970-09-29 Ncr Co En masse encapsulation process
BE791458A (fr) * 1972-07-31 1973-05-16 Merck & Co Inc Produit microencapsule
JPS5432614A (en) * 1977-08-11 1979-03-10 Tanabe Seiyaku Co Ltd Preparation of microcapsules containing pharmaceuticals
CH649217A5 (de) * 1977-08-25 1985-05-15 Sandoz Ag Bromocriptin enthaltende mikrokapseln.

Also Published As

Publication number Publication date
US4389331A (en) 1983-06-21
GB2061866A (en) 1981-05-20
JPS5665821A (en) 1981-06-03
FR2468364B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-05-20
FR2468364A1 (fr) 1981-05-08
CH647675A5 (de) 1985-02-15
DE3039908C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-03-09
IT8025676A0 (it) 1980-10-30
IT1134115B (it) 1986-07-24
GB2061866B (en) 1983-05-11
DE3039908A1 (de) 1981-05-14

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