JPS60185726A - 免疫調整医薬 - Google Patents
免疫調整医薬Info
- Publication number
- JPS60185726A JPS60185726A JP59259048A JP25904884A JPS60185726A JP S60185726 A JPS60185726 A JP S60185726A JP 59259048 A JP59259048 A JP 59259048A JP 25904884 A JP25904884 A JP 25904884A JP S60185726 A JPS60185726 A JP S60185726A
- Authority
- JP
- Japan
- Prior art keywords
- cells
- fragments
- igg
- fragment
- fab
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/809—Drug, bio-affecting and body treating compositions involving immunoglobulin or antibody fragment, e.g. fab', fv, fc, heavy chain or light chain
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/866—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody fragment, e.g. fab', fab, fv, fc, heavy chain or light chain
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8319568 | 1983-12-07 | ||
| FR8319568A FR2556219B1 (fr) | 1983-12-07 | 1983-12-07 | Nouveau medicament immunomodulateur, a base de fragments fc d'igg humaines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS60185726A true JPS60185726A (ja) | 1985-09-21 |
| JPH0586378B2 JPH0586378B2 (enExample) | 1993-12-10 |
Family
ID=9294941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59259048A Granted JPS60185726A (ja) | 1983-12-07 | 1984-12-07 | 免疫調整医薬 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4719107A (enExample) |
| EP (1) | EP0147283B1 (enExample) |
| JP (1) | JPS60185726A (enExample) |
| AT (1) | ATE45498T1 (enExample) |
| CA (1) | CA1229791A (enExample) |
| DE (3) | DE3444765A1 (enExample) |
| FR (1) | FR2556219B1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62153300A (ja) * | 1985-12-26 | 1987-07-08 | Teijin Ltd | ヒト免疫グロブリンＧＦｃ領域蛋白質およびその製造方法 |
| US4925920A (en) * | 1987-05-29 | 1990-05-15 | Brigham And Women's Hospital | Immunosuppressive polypeptides |
| US4814433A (en) * | 1987-09-16 | 1989-03-21 | Miles Inc. | Method for obtaining a papain-free antibody fragment preparation |
| US5681566A (en) * | 1988-10-24 | 1997-10-28 | 3I Research Exploitation Limited | Antibody conjugates with two or more covalently linked FC regions |
| GB8824869D0 (en) * | 1988-10-24 | 1988-11-30 | Stevenson G T | Synthetic antibody |
| FR2639231A1 (fr) * | 1988-11-23 | 1990-05-25 | Merieux Inst | Utilisation de fragments fc d'immunoglobulines g humaines, de peptides analogues du fragment fc, ou d'immunoglobulines g humaines dans l'obtention d'un medicament preparatoire a l'administration chez l'homme, dans un but therapeutique ou de diagnostic, d'anticorps monoclonaux |
| US5328834A (en) * | 1989-09-08 | 1994-07-12 | Unisyn Technologies, Inc. | Method for preparing immunoglobulin fragments |
| GB9009106D0 (en) * | 1990-04-23 | 1990-06-20 | 3I Res Expl Ltd | Processes and intermediates for synthetic antibody derivatives |
| US5230887A (en) * | 1990-07-11 | 1993-07-27 | Immune Network Research Ltd. | Immune system stabilizers for prevention and therapy of disorders associated with immune system disfunction |
| US5219578A (en) * | 1991-02-25 | 1993-06-15 | Innovet, Inc. | Composition and method for immunostimulation in mammals |
| US7425331B2 (en) * | 2002-04-10 | 2008-09-16 | Protalex, Inc. | Protein A methods of use |
| US7211258B2 (en) | 2002-04-10 | 2007-05-01 | Protalex, Inc. | Protein A compositions and methods of use |
| CA2525917C (en) * | 2003-05-16 | 2017-07-04 | Mayo Foundation For Medical Education & Research | Compositions and methods including a recombinant human mab that promotes cns remyelination |
| DE602004031772D1 (de) * | 2003-12-04 | 2011-04-21 | Abbott Biotherapeutics Corp | Anti-ip-10-antikörper |
| US8470318B2 (en) * | 2005-11-07 | 2013-06-25 | The Rockefeller University | Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods |
| US20080206246A1 (en) * | 2006-04-05 | 2008-08-28 | Ravetch Jeffrey V | Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods |
| US20080286819A1 (en) * | 2005-11-07 | 2008-11-20 | Ravetch Jeffrey V | Reagents, Methods and Systems for Selecting a Cytotoxic Antibody or Variant Thereof |
| MX2008012843A (es) * | 2006-04-05 | 2009-01-19 | Univ Rockefeller | Polipeptidos con propiedades antiinflamatorias aumentadas y citotoxicas reducidas y metodos relacionados. |
| JP4866467B2 (ja) | 2007-01-30 | 2012-02-01 | エピバックス インコーポレーテッド | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| US20110150867A1 (en) * | 2007-12-14 | 2011-06-23 | The Rockefeller University | Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods |
| EP2279410B1 (en) * | 2008-04-22 | 2015-11-11 | The Rockefeller University | Methods of identifying anti-inflammatory compounds |
| IL286367B2 (en) | 2014-05-02 | 2023-03-01 | Momenta Pharmaceuticals Inc | Compositions and methods relating to engineered fc constructs |
| US12391759B2 (en) | 2016-03-02 | 2025-08-19 | Momenta Pharmaceuticals, Inc. | Methods related to engineered Fc constructs |
| SG11201810465RA (en) | 2016-05-23 | 2018-12-28 | Momenta Pharmaceuticals Inc | Compositions and methods related to engineered fc constructs |
| CN117886928A (zh) | 2017-01-06 | 2024-04-16 | 动量制药公司 | 与经工程改造的Fc构建体相关的组合物和方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5821624A (ja) * | 1982-04-06 | 1983-02-08 | Tetsuzo Sugizaki | 慢性関節リウマチの治療剤 |
| JPS5821623A (ja) * | 1981-07-28 | 1983-02-08 | Tetsuzo Sugizaki | 抗原抗体複合体沈着疾患治療剤 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2222083B1 (enExample) * | 1973-03-22 | 1976-05-14 | Fontaine Michel | |
| FR2267115B1 (enExample) * | 1974-04-12 | 1977-11-10 | Merieux Inst | |
| DE2846412A1 (de) * | 1978-10-25 | 1980-05-08 | Behringwerke Ag | Mittel zur behandlung allergischer reaktionen |
| DE2853453A1 (de) * | 1978-12-11 | 1980-06-19 | Behringwerke Ag | Mittel zur therapie von immunkomplexerkrankungen |
| EP0091760B1 (en) * | 1982-04-09 | 1986-07-02 | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. | Anti immune complex antibody and preparation thereof |
| US4465670A (en) * | 1982-07-23 | 1984-08-14 | Dainippon Pharmaceutical Co., Ltd. | Method for the treatment of systemic lupus erythematosus and primary glomerulonephritis and agent therefor |
-
1983
- 1983-12-07 FR FR8319568A patent/FR2556219B1/fr not_active Expired
-
1984
- 1984-12-07 CA CA000469658A patent/CA1229791A/fr not_active Expired
- 1984-12-07 AT AT84402531T patent/ATE45498T1/de active
- 1984-12-07 DE DE19843444765 patent/DE3444765A1/de not_active Ceased
- 1984-12-07 US US06/679,445 patent/US4719107A/en not_active Expired - Fee Related
- 1984-12-07 JP JP59259048A patent/JPS60185726A/ja active Granted
- 1984-12-07 DE DE8484402531T patent/DE3479398D1/de not_active Expired
- 1984-12-07 EP EP84402531A patent/EP0147283B1/fr not_active Expired
- 1984-12-07 DE DE198484402531T patent/DE147283T1/de active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5821623A (ja) * | 1981-07-28 | 1983-02-08 | Tetsuzo Sugizaki | 抗原抗体複合体沈着疾患治療剤 |
| JPS5821624A (ja) * | 1982-04-06 | 1983-02-08 | Tetsuzo Sugizaki | 慢性関節リウマチの治療剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA1229791A (fr) | 1987-12-01 |
| US4719107A (en) | 1988-01-12 |
| EP0147283B1 (fr) | 1989-08-16 |
| DE3444765A1 (de) | 1985-06-20 |
| EP0147283A3 (en) | 1985-08-14 |
| DE147283T1 (de) | 1986-04-10 |
| ATE45498T1 (de) | 1989-09-15 |
| DE3479398D1 (en) | 1989-09-21 |
| EP0147283A2 (fr) | 1985-07-03 |
| FR2556219A1 (fr) | 1985-06-14 |
| JPH0586378B2 (enExample) | 1993-12-10 |
| FR2556219B1 (fr) | 1987-06-26 |
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