JPS59205375A - ピロキシカムの塩基塩の製剤化方法 - Google Patents

ピロキシカムの塩基塩の製剤化方法

Info

Publication number
JPS59205375A
JPS59205375A JP59083624A JP8362484A JPS59205375A JP S59205375 A JPS59205375 A JP S59205375A JP 59083624 A JP59083624 A JP 59083624A JP 8362484 A JP8362484 A JP 8362484A JP S59205375 A JPS59205375 A JP S59205375A
Authority
JP
Japan
Prior art keywords
piroxicam
solvent
carrier
salt
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59083624A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0251527B2 (https=
Inventor
メルヴイン・マツケンジ−・ノ−ズワ−シイ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of JPS59205375A publication Critical patent/JPS59205375A/ja
Publication of JPH0251527B2 publication Critical patent/JPH0251527B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/08—1,3-Thiazines; Hydrogenated 1,3-thiazines condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
JP59083624A 1983-04-25 1984-04-25 ピロキシカムの塩基塩の製剤化方法 Granted JPS59205375A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48830383A 1983-04-25 1983-04-25
US488303 2009-06-19

Publications (2)

Publication Number Publication Date
JPS59205375A true JPS59205375A (ja) 1984-11-20
JPH0251527B2 JPH0251527B2 (https=) 1990-11-07

Family

ID=23939186

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59083624A Granted JPS59205375A (ja) 1983-04-25 1984-04-25 ピロキシカムの塩基塩の製剤化方法

Country Status (28)

Country Link
EP (1) EP0123520B1 (https=)
JP (1) JPS59205375A (https=)
KR (1) KR840008345A (https=)
AT (1) ATE36531T1 (https=)
AU (1) AU548451B2 (https=)
BG (1) BG40810A3 (https=)
CA (1) CA1213220A (https=)
CS (1) CS246078B2 (https=)
DD (1) DD219672A5 (https=)
DE (1) DE3473454D1 (https=)
DK (1) DK165168C (https=)
EG (1) EG17887A (https=)
ES (1) ES8505365A1 (https=)
FI (1) FI82377C (https=)
GR (1) GR81938B (https=)
GT (1) GT198404085A (https=)
HU (1) HU194217B (https=)
IE (1) IE57327B1 (https=)
IL (1) IL71598A (https=)
MX (1) MX159889A (https=)
NO (1) NO165177C (https=)
NZ (1) NZ207930A (https=)
PH (1) PH18864A (https=)
PL (1) PL144064B1 (https=)
PT (1) PT78473B (https=)
RO (1) RO88420A (https=)
YU (1) YU44232B (https=)
ZA (1) ZA843013B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02172918A (ja) * 1988-10-28 1990-07-04 Egyt Gyogyszervegyeszeti Gyar Ｎ―（２―ピリジル）―２―メチル―４―ヒドロキシ―２ｈ―１，２―ベンゾチアジン―３―カルボオキサミド―１，１―ジオキシドを含む薬剤及びその製造方法
JP2010083826A (ja) * 2008-10-01 2010-04-15 Nihon Generic Co Ltd オキシカム系化合物を含む固形製剤を製造する方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582831A (en) * 1984-11-16 1986-04-15 Pfizer Inc. Anti-inflammatory polymorphic monoethanolamine salt of N-(2-pyridyl)-2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide compound, composition, and method of use therefor
GB9212450D0 (en) * 1992-06-11 1992-07-22 Indena Spa New derivatives of non-steroidal anti-inflammatory,analgesic and/or antipyretic substances,their use and pharmaceutical formulations containing them
KR100446829B1 (ko) * 2002-02-20 2004-09-04 한국유나이티드제약 주식회사 가용화된 피록시캄을 함유한 확산형 정제의 조성물 및그의 제조방법
KR100791160B1 (ko) * 2006-05-30 2008-01-02 조선대학교산학협력단 멜록시캄의 에탄올아민염 및 이를 함유하는 약제학적조성물

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57209288A (en) * 1981-06-01 1982-12-22 Pfizer Water-soluble basic salt of benzothiazine dioxide and antiarthritic

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4434164A (en) * 1981-06-01 1984-02-28 Pfizer Inc. Crystalline benzothiazine dioxide salts

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57209288A (en) * 1981-06-01 1982-12-22 Pfizer Water-soluble basic salt of benzothiazine dioxide and antiarthritic

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02172918A (ja) * 1988-10-28 1990-07-04 Egyt Gyogyszervegyeszeti Gyar Ｎ―（２―ピリジル）―２―メチル―４―ヒドロキシ―２ｈ―１，２―ベンゾチアジン―３―カルボオキサミド―１，１―ジオキシドを含む薬剤及びその製造方法
JP2010083826A (ja) * 2008-10-01 2010-04-15 Nihon Generic Co Ltd オキシカム系化合物を含む固形製剤を製造する方法

Also Published As

Publication number Publication date
FI82377B (fi) 1990-11-30
ATE36531T1 (de) 1988-09-15
IL71598A0 (en) 1984-07-31
DK165168B (da) 1992-10-19
RO88420A (ro) 1986-01-30
IE57327B1 (en) 1992-07-29
NO165177B (no) 1990-10-01
FI82377C (fi) 1991-03-11
ES531866A0 (es) 1985-05-16
AU2716084A (en) 1984-11-01
AU548451B2 (en) 1985-12-12
KR840008345A (ko) 1984-12-14
PL247378A1 (en) 1985-03-26
YU72484A (en) 1988-04-30
ZA843013B (en) 1985-12-24
CA1213220A (en) 1986-10-28
FI841604L (fi) 1984-10-26
ES8505365A1 (es) 1985-05-16
DE3473454D1 (en) 1988-09-22
BG40810A3 (bg) 1987-02-16
DK204484A (da) 1984-10-26
IL71598A (en) 1987-01-30
PT78473A (en) 1984-05-01
JPH0251527B2 (https=) 1990-11-07
PT78473B (en) 1986-08-28
FI841604A0 (fi) 1984-04-24
EP0123520B1 (en) 1988-08-17
CS246078B2 (en) 1986-10-16
NO841611L (no) 1984-10-26
HU194217B (en) 1988-01-28
PH18864A (en) 1985-10-21
GT198404085A (es) 1985-10-16
EP0123520A1 (en) 1984-10-31
DD219672A5 (de) 1985-03-13
NZ207930A (en) 1986-09-10
EG17887A (en) 1991-03-30
IE840982L (en) 1984-10-25
DK165168C (da) 1993-03-08
PL144064B1 (en) 1988-04-30
HUT34023A (en) 1985-01-28
GR81938B (https=) 1984-12-12
MX159889A (es) 1989-09-27
NO165177C (no) 1991-01-09
YU44232B (en) 1990-04-30
DK204484D0 (da) 1984-04-24

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