JPS59172442A - Ｎ−アルキル化アミノ酸およびそのエステルの製法 - Google Patents

Ｎ−アルキル化アミノ酸およびそのエステルの製法

Info

Publication number
JPS59172442A
JPS59172442A JP59015297A JP1529784A JPS59172442A JP S59172442 A JPS59172442 A JP S59172442A JP 59015297 A JP59015297 A JP 59015297A JP 1529784 A JP1529784 A JP 1529784A JP S59172442 A JPS59172442 A JP S59172442A
Authority
JP
Japan
Prior art keywords
alkyl
optionally substituted
carbon atoms
aryl
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59015297A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0587499B2 (enExample
Inventor
ハンスイエルク・ウルバッハ
ライネル・ヘニング
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of JPS59172442A publication Critical patent/JPS59172442A/ja
Publication of JPH0587499B2 publication Critical patent/JPH0587499B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP59015297A 1983-02-02 1984-02-01 Ｎ−アルキル化アミノ酸およびそのエステルの製法 Granted JPS59172442A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3303344.7 1983-02-02
DE19833303344 DE3303344A1 (de) 1983-02-02 1983-02-02 Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP4289760A Division JPH06102646B2 (ja) 1983-02-02 1992-10-28 トリフルオロメタンスルホニルオキシカルボン酸誘導体およびその製法

Publications (2)

Publication Number Publication Date
JPS59172442A true JPS59172442A (ja) 1984-09-29
JPH0587499B2 JPH0587499B2 (enExample) 1993-12-16

Family

ID=6189750

Family Applications (2)

Application Number Title Priority Date Filing Date
JP59015297A Granted JPS59172442A (ja) 1983-02-02 1984-02-01 Ｎ−アルキル化アミノ酸およびそのエステルの製法
JP4289760A Expired - Fee Related JPH06102646B2 (ja) 1983-02-02 1992-10-28 トリフルオロメタンスルホニルオキシカルボン酸誘導体およびその製法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP4289760A Expired - Fee Related JPH06102646B2 (ja) 1983-02-02 1992-10-28 トリフルオロメタンスルホニルオキシカルボン酸誘導体およびその製法

Country Status (14)

Country Link
EP (1) EP0117448B1 (enExample)
JP (2) JPS59172442A (enExample)
KR (1) KR910008135B1 (enExample)
AT (1) ATE21890T1 (enExample)
AU (2) AU566053B2 (enExample)
CA (2) CA1292236C (enExample)
DE (2) DE3303344A1 (enExample)
DK (2) DK166619C (enExample)
ES (1) ES529302A0 (enExample)
GR (1) GR79751B (enExample)
IE (1) IE56751B1 (enExample)
IL (1) IL70847A (enExample)
PT (1) PT78047B (enExample)
ZA (1) ZA84740B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63170344A (ja) * 1987-01-09 1988-07-14 Daicel Chem Ind Ltd アミノ酸エステルのｎ−アルキル化法
JPS63174955A (ja) * 1987-01-13 1988-07-19 Daicel Chem Ind Ltd Ｎ−アルキル化アミノ酸エステルの製法

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3648935A (en) * 1970-02-04 1972-03-14 Amchem Prod Spray apparatus with movable head
DE3303344A1 (de) * 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern
US4801721A (en) * 1984-08-16 1989-01-31 Ryan James W Stereospecific synthesis of carboxyalkyl peptides
DE3431591A1 (de) * 1984-08-28 1986-03-13 Diamalt AG, 8000 München Verfahren zur herstellung von aminoverbindungen aus hydroxylverbindungen
FR2620699B1 (fr) * 1987-09-17 1990-06-01 Adir Procede de synthese d'alpha amino acides n alkyles et de leurs esters. application a la synthese de carboxyalkyl dipeptides
US5055588A (en) * 1988-07-06 1991-10-08 Daicel Chemical Industries Ltd. Process for preparing N-substituted amino acid esters
SE0000382D0 (sv) 2000-02-07 2000-02-07 Astrazeneca Ab New process
WO2002076375A2 (en) 2001-03-27 2002-10-03 Ranbaxy Laboratories Limited Process for the preparation of benazepril
WO2008032463A1 (en) 2006-09-12 2008-03-20 Wako Pure Chemical Industries, Ltd. Process for production of sulfonic acid ester
PL2935222T3 (pl) 2012-12-21 2019-02-28 Epizyme Inc Inhibitory PRMT5 i ich zastosowania

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3419595A (en) * 1965-03-05 1968-12-31 Minnesota Mining & Mfg Fluorocarbon fluoroalkanesulfonates
NL144484B (nl) * 1967-07-26 1975-01-15 Merck & Co Inc Werkwijze ter bereiding van een geneesmiddel met anti-anflammatoire werking, alsmede werkwijze ter bereiding van de anti-inflammatoir werkzame aralkylmercaptoaminozuren.
GB1572185A (en) * 1975-10-25 1980-07-23 Beecham Group Ltd Intermediates for the preparation of 12-azaprostaglandins
DE3044236A1 (de) 1980-11-25 1982-06-16 Hoechst Ag, 6000 Frankfurt Aminosaeurederivate und verfahren zu ihrer herstellung
DE2937779A1 (de) 1979-09-19 1981-04-09 Hoechst Ag, 6000 Frankfurt Aminosaeurederivate und verfahren zu ihrer herstellung
FR2503155A2 (fr) 1980-10-02 1982-10-08 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
FR2487829A2 (fr) 1979-12-07 1982-02-05 Science Union & Cie Nouveaux imino acides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
IE52663B1 (en) 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
US4350704A (en) 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
EP0278530A3 (de) 1980-08-30 1989-08-02 Hoechst Aktiengesellschaft Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung
US4344949A (en) 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
FR2492381A1 (fr) 1980-10-21 1982-04-23 Science Union & Cie Nouveaux acides aza bicyclo alcane carboxyliques substitues leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
DE19575012I2 (de) 1980-10-23 2002-01-24 Schering Corp Carboxyalkyl-Dipeptide Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
US4374847A (en) 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
DE3226768A1 (de) 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
DE3151690A1 (de) 1981-12-29 1983-07-07 Hoechst Ag, 6230 Frankfurt "neue derivate bicyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung"
DE3210496A1 (de) 1982-03-23 1983-10-06 Hoechst Ag Neue derivate bicyclischer aminsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
DE3211397A1 (de) 1982-03-27 1983-11-10 Hoechst Ag, 6230 Frankfurt Spiro (4.(3+n))-2-aza-3-carbonsaeure-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
DE3211676A1 (de) 1982-03-30 1983-10-06 Hoechst Ag Neue derivate von cycloalka (c) pyrrol-carbonsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue cycloalka (c) pyrrol-carbonsaeuren als zwischenstufen und verfahren zu deren herstellung
DE3227055A1 (de) 1982-07-20 1984-01-26 Hoechst Ag, 6230 Frankfurt Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung
DE3242151A1 (de) 1982-11-13 1984-05-17 Hoechst Ag, 6230 Frankfurt Neue derivate tricyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung, sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
DE3246503A1 (de) 1982-12-16 1984-06-20 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(5.3.0)-decan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
DE3246757A1 (de) 1982-12-17 1984-06-20 Hoechst Ag, 6230 Frankfurt Neue 2-azabicyclo(2.2.1)heptan-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-azabicyclo(2.2.1)heptan-derivate als zwischenprodukte und verfahren zu deren herstellung
DE3303344A1 (de) * 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63170344A (ja) * 1987-01-09 1988-07-14 Daicel Chem Ind Ltd アミノ酸エステルのｎ−アルキル化法
JPS63174955A (ja) * 1987-01-13 1988-07-19 Daicel Chem Ind Ltd Ｎ−アルキル化アミノ酸エステルの製法

Also Published As

Publication number Publication date
DK166619B (da) 1993-06-21
AU566053B2 (en) 1987-10-08
ES8500215A1 (es) 1984-10-01
DK173770B1 (da) 2001-09-24
AU7830487A (en) 1987-12-17
DK45584D0 (da) 1984-02-01
EP0117448A1 (de) 1984-09-05
CA1267903A (en) 1990-04-17
DE3460578D1 (en) 1986-10-09
IE840244L (en) 1984-08-02
PT78047A (de) 1984-03-01
IL70847A (en) 1991-04-15
CA1292236C (en) 1991-11-19
DK49492A (da) 1992-04-13
AU2399884A (en) 1984-08-09
KR850000384A (ko) 1985-02-27
DK49492D0 (da) 1992-04-13
JPH0587499B2 (enExample) 1993-12-16
DK45584A (da) 1984-08-03
PT78047B (de) 1986-07-15
ES529302A0 (es) 1984-10-01
JPH06102646B2 (ja) 1994-12-14
GR79751B (enExample) 1984-10-31
KR910008135B1 (ko) 1991-10-10
IL70847A0 (en) 1984-05-31
ATE21890T1 (de) 1986-09-15
AU588483B2 (en) 1989-09-14
EP0117448B1 (de) 1986-09-03
IE56751B1 (en) 1991-12-04
ZA84740B (en) 1984-09-26
DK166619C (da) 1993-11-08
JPH05320119A (ja) 1993-12-03
DE3303344A1 (de) 1984-08-02

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