JPS59134729A - う蝕菌生育阻害剤 - Google Patents
う蝕菌生育阻害剤Info
- Publication number
- JPS59134729A JPS59134729A JP58009685A JP968583A JPS59134729A JP S59134729 A JPS59134729 A JP S59134729A JP 58009685 A JP58009685 A JP 58009685A JP 968583 A JP968583 A JP 968583A JP S59134729 A JPS59134729 A JP S59134729A
- Authority
- JP
- Japan
- Prior art keywords
- bacteria
- growth
- organic solvent
- licorice
- hydrophilic organic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000894006 Bacteria Species 0.000 title abstract description 28
- 239000003112 inhibitor Substances 0.000 title abstract 3
- 239000003960 organic solvent Substances 0.000 claims abstract description 11
- 241000196324 Embryophyta Species 0.000 claims abstract description 9
- 241000202807 Glycyrrhiza Species 0.000 claims abstract description 9
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims abstract description 9
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 9
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims abstract description 9
- 229940010454 licorice Drugs 0.000 claims abstract description 9
- 240000000249 Morus alba Species 0.000 claims abstract description 8
- 235000008708 Morus alba Nutrition 0.000 claims abstract description 8
- 239000000284 extract Substances 0.000 claims abstract description 7
- 239000004480 active ingredient Substances 0.000 claims abstract description 3
- 239000003966 growth inhibitor Substances 0.000 claims description 12
- 230000001013 cariogenic effect Effects 0.000 claims description 5
- 241000233866 Fungi Species 0.000 claims description 4
- 244000068988 Glycine max Species 0.000 claims 1
- 235000010469 Glycine max Nutrition 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract description 12
- 241000194019 Streptococcus mutans Species 0.000 abstract description 9
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract description 6
- 239000000126 substance Substances 0.000 abstract description 5
- 239000002994 raw material Substances 0.000 abstract description 3
- 230000000694 effects Effects 0.000 abstract description 2
- 239000004094 surface-active agent Substances 0.000 abstract description 2
- 239000000606 toothpaste Substances 0.000 abstract description 2
- 241000132012 Atractylodes Species 0.000 abstract 2
- 210000000936 intestine Anatomy 0.000 abstract 2
- 210000000582 semen Anatomy 0.000 abstract 2
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000000419 plant extract Substances 0.000 abstract 1
- 229940034610 toothpaste Drugs 0.000 abstract 1
- 208000002925 dental caries Diseases 0.000 description 13
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 9
- 239000000203 mixture Substances 0.000 description 9
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 9
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- 230000000844 anti-bacterial effect Effects 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 229920001817 Agar Polymers 0.000 description 5
- 239000008272 agar Substances 0.000 description 5
- 230000000968 intestinal effect Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- 239000003242 anti bacterial agent Substances 0.000 description 4
- 239000012141 concentrate Substances 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 241000193830 Bacillus <bacterium> Species 0.000 description 3
- 241000186018 Bifidobacterium adolescentis Species 0.000 description 3
- 241000588724 Escherichia coli Species 0.000 description 3
- 229940088710 antibiotic agent Drugs 0.000 description 3
- 235000015218 chewing gum Nutrition 0.000 description 3
- 229940112822 chewing gum Drugs 0.000 description 3
- 239000000706 filtrate Substances 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 241000194017 Streptococcus Species 0.000 description 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 238000012258 culturing Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 230000009036 growth inhibition Effects 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 238000001802 infusion Methods 0.000 description 2
- 238000004898 kneading Methods 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 239000006072 paste Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 241000208838 Asteraceae Species 0.000 description 1
- 241000606125 Bacteroides Species 0.000 description 1
- 241000186000 Bifidobacterium Species 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 208000002064 Dental Plaque Diseases 0.000 description 1
- 241000305071 Enterobacterales Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 244000308760 Helichrysum petiolatum Species 0.000 description 1
- 235000013537 Helichrysum petiolatum Nutrition 0.000 description 1
- 241000218231 Moraceae Species 0.000 description 1
- 241000750138 Streptococcus sinensis Species 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 210000003298 dental enamel Anatomy 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 230000002101 lytic effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002324 mouth wash Substances 0.000 description 1
- 229940051866 mouthwash Drugs 0.000 description 1
- 235000021096 natural sweeteners Nutrition 0.000 description 1
- 239000002417 nutraceutical Substances 0.000 description 1
- 235000021436 nutraceutical agent Nutrition 0.000 description 1
- 239000007935 oral tablet Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000012264 purified product Substances 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 235000013555 soy sauce Nutrition 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000013076 target substance Substances 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58009685A JPS59134729A (ja) | 1983-01-24 | 1983-01-24 | う蝕菌生育阻害剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58009685A JPS59134729A (ja) | 1983-01-24 | 1983-01-24 | う蝕菌生育阻害剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS59134729A true JPS59134729A (ja) | 1984-08-02 |
| JPS6324489B2 JPS6324489B2 (enrdf_load_stackoverflow) | 1988-05-20 |
Family
ID=11727059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58009685A Granted JPS59134729A (ja) | 1983-01-24 | 1983-01-24 | う蝕菌生育阻害剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS59134729A (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63198616A (ja) * | 1987-02-13 | 1988-08-17 | Yasutake Hichi | 抗齲蝕剤 |
| JPH072687A (ja) * | 1993-04-19 | 1995-01-06 | Shinsei Shokuhin Kogyo Kk | 抗齲蝕剤及び抗菌活性物質 |
| KR101641215B1 (ko) * | 2015-05-15 | 2016-07-20 | 대한민국(환경부 국립생물자원관장) | 상백피추출물과 화살나무추출물을 유효성분으로 포함하는 충치 예방 및 치료용 구강조성물 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5857320A (ja) * | 1981-10-01 | 1983-04-05 | Tsurui Yakuhin Kogyo Kk | 歯苔形成抑制剤 |
-
1983
- 1983-01-24 JP JP58009685A patent/JPS59134729A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5857320A (ja) * | 1981-10-01 | 1983-04-05 | Tsurui Yakuhin Kogyo Kk | 歯苔形成抑制剤 |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63198616A (ja) * | 1987-02-13 | 1988-08-17 | Yasutake Hichi | 抗齲蝕剤 |
| JPH072687A (ja) * | 1993-04-19 | 1995-01-06 | Shinsei Shokuhin Kogyo Kk | 抗齲蝕剤及び抗菌活性物質 |
| KR101641215B1 (ko) * | 2015-05-15 | 2016-07-20 | 대한민국(환경부 국립생물자원관장) | 상백피추출물과 화살나무추출물을 유효성분으로 포함하는 충치 예방 및 치료용 구강조성물 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6324489B2 (enrdf_load_stackoverflow) | 1988-05-20 |
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