JPS58183676A - オキサゾ−ル誘導体 - Google Patents

オキサゾ−ル誘導体

Info

Publication number
JPS58183676A
JPS58183676A JP57066124A JP6612482A JPS58183676A JP S58183676 A JPS58183676 A JP S58183676A JP 57066124 A JP57066124 A JP 57066124A JP 6612482 A JP6612482 A JP 6612482A JP S58183676 A JPS58183676 A JP S58183676A
Authority
JP
Japan
Prior art keywords
water
solvent
yield
compound
distilled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57066124A
Other languages
English (en)
Japanese (ja)
Inventor
Kanji Meguro
寛司 目黒
Takeshi Fujita
剛 藤田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP57066124A priority Critical patent/JPS58183676A/ja
Priority to CA000425700A priority patent/CA1195985A/en
Priority to FI831253A priority patent/FI831253A7/fi
Priority to AU13552/83A priority patent/AU1355283A/en
Priority to ZA832657A priority patent/ZA832657B/xx
Priority to US06/485,433 priority patent/US4596816A/en
Priority to GR71110A priority patent/GR79251B/el
Priority to NO831361A priority patent/NO831361L/no
Priority to PT76563A priority patent/PT76563B/pt
Priority to EP83103787A priority patent/EP0092239A3/en
Priority to HU831358A priority patent/HU187002B/hu
Priority to DK172183A priority patent/DK172183A/da
Priority to ES521865A priority patent/ES8603174A1/es
Publication of JPS58183676A publication Critical patent/JPS58183676A/ja
Priority to KR1019830001606A priority patent/KR840004415A/ko
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP57066124A 1982-04-19 1982-04-19 オキサゾ−ル誘導体 Pending JPS58183676A (ja)

Priority Applications (14)

Application Number Priority Date Filing Date Title
JP57066124A JPS58183676A (ja) 1982-04-19 1982-04-19 オキサゾ−ル誘導体
CA000425700A CA1195985A (en) 1982-04-19 1983-04-12 Oxazole derivatives, production and use thereof
FI831253A FI831253A7 (fi) 1982-04-19 1983-04-14 Menetelmä uusien oksatsolijohdosten valmistamiseksi.
AU13552/83A AU1355283A (en) 1982-04-19 1983-04-15 Oxazole derivatives
ZA832657A ZA832657B (en) 1982-04-19 1983-04-15 Oxazole derivatives,production and use thereof
US06/485,433 US4596816A (en) 1982-04-19 1983-04-15 4-aryl oxazoles
NO831361A NO831361L (no) 1982-04-19 1983-04-18 Fremgangsmaate ved fremstilling av terapeutisk aktive oxazolderivater.
GR71110A GR79251B (en:Method) 1982-04-19 1983-04-18
PT76563A PT76563B (en) 1982-04-19 1983-04-18 Oxazole derivatives and use thereof
EP83103787A EP0092239A3 (en) 1982-04-19 1983-04-19 Oxazole derivatives, production and use thereof
HU831358A HU187002B (en) 1982-04-19 1983-04-19 Process for preparing oxazole derivatives and pharmaceutical compositions containing such compounds
DK172183A DK172183A (da) 1982-04-19 1983-04-19 Ozazolderivater, deres fremstilling og anvendelse
ES521865A ES8603174A1 (es) 1982-04-19 1983-04-19 Procedimiento de producir derivados oxazolicos.
KR1019830001606A KR840004415A (ko) 1982-04-19 1983-11-16 옥사졸 유도체의 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57066124A JPS58183676A (ja) 1982-04-19 1982-04-19 オキサゾ−ル誘導体

Publications (1)

Publication Number Publication Date
JPS58183676A true JPS58183676A (ja) 1983-10-26

Family

ID=13306807

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57066124A Pending JPS58183676A (ja) 1982-04-19 1982-04-19 オキサゾ−ル誘導体

Country Status (14)

Country Link
US (1) US4596816A (en:Method)
EP (1) EP0092239A3 (en:Method)
JP (1) JPS58183676A (en:Method)
KR (1) KR840004415A (en:Method)
AU (1) AU1355283A (en:Method)
CA (1) CA1195985A (en:Method)
DK (1) DK172183A (en:Method)
ES (1) ES8603174A1 (en:Method)
FI (1) FI831253A7 (en:Method)
GR (1) GR79251B (en:Method)
HU (1) HU187002B (en:Method)
NO (1) NO831361L (en:Method)
PT (1) PT76563B (en:Method)
ZA (1) ZA832657B (en:Method)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4632930A (en) * 1984-11-30 1986-12-30 E. I. Du Pont De Nemours And Company Antihypertensive alkyl-arylimidazole, thiazole and oxazole derivatives
ZW19786A1 (en) * 1985-10-17 1988-05-18 Hoffmann La Roche Heterocyclic compounds
GB8531608D0 (en) * 1985-12-23 1986-02-05 Beecham Group Plc Treatment
HU203330B (en) * 1987-06-10 1991-07-29 Pfizer Process for producing oxazolidin-2-one derivatives and hypoglychemic pharmaceutical compositions containing them
US5239080A (en) * 1989-02-08 1993-08-24 Takeda Chemical Industries, Ltd. Oxazole compounds and their use as antidiabetic and bone-reduction inhibitory agents
EP0440183A1 (en) * 1990-02-01 1991-08-07 Takeda Chemical Industries, Ltd. Oxazole compounds, their production and use
FR2699172B1 (fr) * 1992-12-11 1995-01-20 Adir Nouveaux dérivés de 4-méthyl-1,3-oxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
DE69717091T2 (de) 1996-04-03 2003-07-31 Takeda Chemical Industries, Ltd. Oxazole derivate,ihre herstellung und verwendung
US6699896B1 (en) 1998-05-12 2004-03-02 Wyeth Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
WO1999058511A1 (en) * 1998-05-12 1999-11-18 American Home Products Corporation Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
CN1308620A (zh) * 1998-05-12 2001-08-15 美国家用产品公司 用于治疗胰岛素抗性和高血糖的联苯基磺酰基芳基羧酸
AU2002246397B2 (en) 2001-04-16 2005-03-24 Tanabe Seiyaku Co., Ltd. Imidazole, thiazole and oxazole derivatives and their use for the manufacture of a medicament for the treatment and/or prevention of pollakiuria or urinary incontinence

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226548A (en:Method) * 1967-06-14 1971-03-31 Wyeth John & Brother Ltd
GB1245087A (en) * 1967-10-26 1971-09-02 Wyeth John & Brother Ltd Heterocyclic compounds
US3578671A (en) * 1967-11-06 1971-05-11 Wyeth John & Brother Ltd Oxazoles

Also Published As

Publication number Publication date
FI831253A0 (fi) 1983-04-14
HU187002B (en) 1985-10-28
PT76563B (en) 1986-05-07
FI831253L (fi) 1983-10-20
KR840004415A (ko) 1984-10-15
EP0092239A2 (en) 1983-10-26
NO831361L (no) 1983-10-20
AU1355283A (en) 1983-10-27
CA1195985A (en) 1985-10-29
GR79251B (en:Method) 1984-10-22
DK172183A (da) 1983-10-20
EP0092239A3 (en) 1985-01-23
ES521865A0 (es) 1985-05-16
ZA832657B (en) 1984-01-25
FI831253A7 (fi) 1983-10-20
DK172183D0 (da) 1983-04-19
US4596816A (en) 1986-06-24
ES8603174A1 (es) 1985-05-16
PT76563A (en) 1983-05-01

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