JPS58103358A - 抗生物質中間体の製造方法 - Google Patents

抗生物質中間体の製造方法

Info

Publication number
JPS58103358A
JPS58103358A JP57184794A JP18479482A JPS58103358A JP S58103358 A JPS58103358 A JP S58103358A JP 57184794 A JP57184794 A JP 57184794A JP 18479482 A JP18479482 A JP 18479482A JP S58103358 A JPS58103358 A JP S58103358A
Authority
JP
Japan
Prior art keywords
formula
compound
mmol
alkyl
reacted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57184794A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0427978B2 (cs
Inventor
エドワ−ド・ジエ−・ジエ−・グラボウスキ
ポ−ル・ジエ−・レイダ−
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS58103358A publication Critical patent/JPS58103358A/ja
Publication of JPH0427978B2 publication Critical patent/JPH0427978B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP57184794A 1981-10-23 1982-10-22 抗生物質中間体の製造方法 Granted JPS58103358A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US31415281A 1981-10-23 1981-10-23
US314152 1982-06-14
US367532 1982-06-14
US388373 1982-06-14

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP3062761A Division JPH06102649B2 (ja) 1981-10-23 1991-01-09 抗生物質中間体の製造方法

Publications (2)

Publication Number Publication Date
JPS58103358A true JPS58103358A (ja) 1983-06-20
JPH0427978B2 JPH0427978B2 (cs) 1992-05-13

Family

ID=23218781

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57184794A Granted JPS58103358A (ja) 1981-10-23 1982-10-22 抗生物質中間体の製造方法

Country Status (1)

Country Link
JP (1) JPS58103358A (cs)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59170096A (ja) * 1983-03-07 1984-09-26 ブリストル―マイヤーズ　スクイブ　カンパニー カルバペネム中間体
JPS6054358A (ja) * 1983-08-04 1985-03-28 フア−ミタリア・カルロ・エルバ・ソシエタ・ペル・アツイオ−ニ アゼチジノン類の製法
EP0204440A1 (en) 1985-05-09 1986-12-10 Yamanouchi Pharmaceutical Co. Ltd. Azetidine derivatives production
JPS62192356A (ja) * 1986-02-19 1987-08-22 Sanraku Inc フルオロアルキルβ−ラクタム化合物
EP0567949A1 (en) 1992-04-28 1993-11-03 Tanabe Seiyaku Co., Ltd. Method for removing the protecting group for hydroxy group
US5587474A (en) * 1992-06-18 1996-12-24 Tanabe Seiyaku Co., Ltd. Method for removing the protecting group for carboxyl group

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172895A (en) * 1977-12-28 1979-10-30 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-oxapen-2-em-3-carboxylic acid
JPS56108785A (en) * 1979-04-27 1981-08-28 Merck & Co Inc Manufacture of 33*11hydroxyethyl**azetidinone
JPS5896060A (ja) * 1981-12-01 1983-06-07 Sumitomo Chem Co Ltd β‐ラクタム誘導体の製造法
JPS5899463A (ja) * 1981-12-04 1983-06-13 Sumitomo Chem Co Ltd β−ラクタム誘導体の製造法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172895A (en) * 1977-12-28 1979-10-30 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-oxapen-2-em-3-carboxylic acid
JPS56108785A (en) * 1979-04-27 1981-08-28 Merck & Co Inc Manufacture of 33*11hydroxyethyl**azetidinone
JPS5896060A (ja) * 1981-12-01 1983-06-07 Sumitomo Chem Co Ltd β‐ラクタム誘導体の製造法
JPS5899463A (ja) * 1981-12-04 1983-06-13 Sumitomo Chem Co Ltd β−ラクタム誘導体の製造法

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59170096A (ja) * 1983-03-07 1984-09-26 ブリストル―マイヤーズ　スクイブ　カンパニー カルバペネム中間体
JPH0827168A (ja) * 1983-03-07 1996-01-30 Bristol Myers Squibb Co カルバペネム中間体
JPS6054358A (ja) * 1983-08-04 1985-03-28 フア−ミタリア・カルロ・エルバ・ソシエタ・ペル・アツイオ−ニ アゼチジノン類の製法
EP0204440A1 (en) 1985-05-09 1986-12-10 Yamanouchi Pharmaceutical Co. Ltd. Azetidine derivatives production
JPS62192356A (ja) * 1986-02-19 1987-08-22 Sanraku Inc フルオロアルキルβ−ラクタム化合物
EP0567949A1 (en) 1992-04-28 1993-11-03 Tanabe Seiyaku Co., Ltd. Method for removing the protecting group for hydroxy group
US5260438A (en) * 1992-04-28 1993-11-09 Tanabe Seiyaku Co., Ltd. Method for removing the protecting group for hydroxy group
EP0937725A2 (en) 1992-04-28 1999-08-25 Tanabe Seiyaku Co., Ltd. Method for removing the protecting group for hydroxy group
EP0937725A3 (en) * 1992-04-28 2004-12-01 Tanabe Seiyaku Co., Ltd. Method for removing the protecting group for hydroxy group
US5587474A (en) * 1992-06-18 1996-12-24 Tanabe Seiyaku Co., Ltd. Method for removing the protecting group for carboxyl group

Also Published As

Publication number Publication date
JPH0427978B2 (cs) 1992-05-13

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