JPS5798242A - Preparation of 5-(n-methylaminoalkoxy)carvacrol - Google Patents

Preparation of 5-(n-methylaminoalkoxy)carvacrol

Info

Publication number
JPS5798242A
JPS5798242A JP17381580A JP17381580A JPS5798242A JP S5798242 A JPS5798242 A JP S5798242A JP 17381580 A JP17381580 A JP 17381580A JP 17381580 A JP17381580 A JP 17381580A JP S5798242 A JPS5798242 A JP S5798242A
Authority
JP
Japan
Prior art keywords
carbacrol
derivative
acid
dimethylaminoalkoxy
alkali
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP17381580A
Other languages
Japanese (ja)
Other versions
JPS6026380B2 (en
Inventor
Tetsuyuki Konno
Tokio Morisawa
Shigeto Ichida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FUJI ZOKI SEIYAKU
FUJI ZOUKI SEIYAKU KK
Fujirebio Inc
Original Assignee
FUJI ZOKI SEIYAKU
FUJI ZOUKI SEIYAKU KK
Fujirebio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FUJI ZOKI SEIYAKU, FUJI ZOUKI SEIYAKU KK, Fujirebio Inc filed Critical FUJI ZOKI SEIYAKU
Priority to JP17381580A priority Critical patent/JPS6026380B2/en
Publication of JPS5798242A publication Critical patent/JPS5798242A/en
Publication of JPS6026380B2 publication Critical patent/JPS6026380B2/en
Expired legal-status Critical Current

Links

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To obtain the titled compound useful for circulatory diseases, by reacting a 5-(N,N-dimethylaminoalkoxy)carbacrol or its derivative with a cyanogen chloride, hydrolyzing the reaction product using an acid or an alkali as a catalyst.
CONSTITUTION: A 5-(N,N-dimethylaminoalkoxy)carbacrol shown by the formulaI(R is H or acetyl; n is 2 or 3) or its derivative is reacted with a cyanogen chloride (e.g. CNCl, CNBr, or CNI) in a solvent, e.g., chloroform, carbon tetrachloride, etc. to give a 5-(N,N-methylcyanoaminoalkoxy)carbacrol shown by the formula II or its derivative. This compound is hydrolyzed using an acid, e.g., hydrochloric acid, sulfuric acid, etc. or an alkali, e.g., potassium hydroxide, sodium hydroxide, etc. as a catalyst to give the desired compound shown by the formula III.
COPYRIGHT: (C)1982,JPO&Japio
JP17381580A 1980-12-11 1980-12-11 Method for producing 5-(N-methylaminoalkoxy)carvacrol Expired JPS6026380B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP17381580A JPS6026380B2 (en) 1980-12-11 1980-12-11 Method for producing 5-(N-methylaminoalkoxy)carvacrol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17381580A JPS6026380B2 (en) 1980-12-11 1980-12-11 Method for producing 5-(N-methylaminoalkoxy)carvacrol

Publications (2)

Publication Number Publication Date
JPS5798242A true JPS5798242A (en) 1982-06-18
JPS6026380B2 JPS6026380B2 (en) 1985-06-24

Family

ID=15967661

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17381580A Expired JPS6026380B2 (en) 1980-12-11 1980-12-11 Method for producing 5-(N-methylaminoalkoxy)carvacrol

Country Status (1)

Country Link
JP (1) JPS6026380B2 (en)

Also Published As

Publication number Publication date
JPS6026380B2 (en) 1985-06-24

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