JPS5798242A - Preparation of 5-(n-methylaminoalkoxy)carvacrol - Google Patents
Preparation of 5-(n-methylaminoalkoxy)carvacrolInfo
- Publication number
- JPS5798242A JPS5798242A JP17381580A JP17381580A JPS5798242A JP S5798242 A JPS5798242 A JP S5798242A JP 17381580 A JP17381580 A JP 17381580A JP 17381580 A JP17381580 A JP 17381580A JP S5798242 A JPS5798242 A JP S5798242A
- Authority
- JP
- Japan
- Prior art keywords
- carbacrol
- derivative
- acid
- dimethylaminoalkoxy
- alkali
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain the titled compound useful for circulatory diseases, by reacting a 5-(N,N-dimethylaminoalkoxy)carbacrol or its derivative with a cyanogen chloride, hydrolyzing the reaction product using an acid or an alkali as a catalyst.
CONSTITUTION: A 5-(N,N-dimethylaminoalkoxy)carbacrol shown by the formulaI(R is H or acetyl; n is 2 or 3) or its derivative is reacted with a cyanogen chloride (e.g. CNCl, CNBr, or CNI) in a solvent, e.g., chloroform, carbon tetrachloride, etc. to give a 5-(N,N-methylcyanoaminoalkoxy)carbacrol shown by the formula II or its derivative. This compound is hydrolyzed using an acid, e.g., hydrochloric acid, sulfuric acid, etc. or an alkali, e.g., potassium hydroxide, sodium hydroxide, etc. as a catalyst to give the desired compound shown by the formula III.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17381580A JPS6026380B2 (en) | 1980-12-11 | 1980-12-11 | Method for producing 5-(N-methylaminoalkoxy)carvacrol |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17381580A JPS6026380B2 (en) | 1980-12-11 | 1980-12-11 | Method for producing 5-(N-methylaminoalkoxy)carvacrol |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5798242A true JPS5798242A (en) | 1982-06-18 |
JPS6026380B2 JPS6026380B2 (en) | 1985-06-24 |
Family
ID=15967661
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP17381580A Expired JPS6026380B2 (en) | 1980-12-11 | 1980-12-11 | Method for producing 5-(N-methylaminoalkoxy)carvacrol |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6026380B2 (en) |
-
1980
- 1980-12-11 JP JP17381580A patent/JPS6026380B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS6026380B2 (en) | 1985-06-24 |
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