JPS5566550A - Preparation of o-(2,6-dichloroanilino)-phenylacetic acid - Google Patents
Preparation of o-(2,6-dichloroanilino)-phenylacetic acidInfo
- Publication number
- JPS5566550A JPS5566550A JP14006878A JP14006878A JPS5566550A JP S5566550 A JPS5566550 A JP S5566550A JP 14006878 A JP14006878 A JP 14006878A JP 14006878 A JP14006878 A JP 14006878A JP S5566550 A JPS5566550 A JP S5566550A
- Authority
- JP
- Japan
- Prior art keywords
- iodophenyl
- acet amide
- dichloroanilino
- preparation
- dichloroaniline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain the title compound useful as an antiinflammatory agent and an analgeic, smoothly in high yield and without side reactions, by hydrolyzing the reaction product of an o-iodophenyl-dialkyl-acet amide with 2,6-dichloroaniline.
CONSTITUTION: An o-iodophenyl-dialkyl-acet amide of the formula (R1 or R2 is a lower alkyl.) is reacted with 2,6-dichloroaniline in a solvent, e.g., DMF, in the presence of a catalyst, e.g., copper powder, or cupric oxide, at an adequate temperature, about 100W150°C, to give an o-iodophenyl dilower alkyl-acet amide. This compound, without separation and purification is hydrolyzed in a solvent, e.g. ethanol, in the presence of NaOH, etc., to obtain the title compound in high yield.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14006878A JPS5566550A (en) | 1978-11-13 | 1978-11-13 | Preparation of o-(2,6-dichloroanilino)-phenylacetic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14006878A JPS5566550A (en) | 1978-11-13 | 1978-11-13 | Preparation of o-(2,6-dichloroanilino)-phenylacetic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5566550A true JPS5566550A (en) | 1980-05-20 |
Family
ID=15260217
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14006878A Pending JPS5566550A (en) | 1978-11-13 | 1978-11-13 | Preparation of o-(2,6-dichloroanilino)-phenylacetic acid |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5566550A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10568782B2 (en) | 2014-08-27 | 2020-02-25 | The Procter & Gamble Company | Wearable article having elastic belt |
US10624797B2 (en) | 2014-08-27 | 2020-04-21 | The Procter & Gamble Company | Wearable article having elastic belt |
US10624799B2 (en) | 2014-08-27 | 2020-04-21 | The Procter & Gamble Company | Wearable article having elastic belt |
US10624798B2 (en) | 2014-08-27 | 2020-04-21 | The Procter & Gamble Company | Wearable article having elastic belt |
-
1978
- 1978-11-13 JP JP14006878A patent/JPS5566550A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10568782B2 (en) | 2014-08-27 | 2020-02-25 | The Procter & Gamble Company | Wearable article having elastic belt |
US10624797B2 (en) | 2014-08-27 | 2020-04-21 | The Procter & Gamble Company | Wearable article having elastic belt |
US10624799B2 (en) | 2014-08-27 | 2020-04-21 | The Procter & Gamble Company | Wearable article having elastic belt |
US10624798B2 (en) | 2014-08-27 | 2020-04-21 | The Procter & Gamble Company | Wearable article having elastic belt |
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