JPS5731697A - Masked compound and its preparation - Google Patents
Masked compound and its preparationInfo
- Publication number
- JPS5731697A JPS5731697A JP10641980A JP10641980A JPS5731697A JP S5731697 A JPS5731697 A JP S5731697A JP 10641980 A JP10641980 A JP 10641980A JP 10641980 A JP10641980 A JP 10641980A JP S5731697 A JPS5731697 A JP S5731697A
- Authority
- JP
- Japan
- Prior art keywords
- bleomycin
- formula
- expressed
- compound
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 108010006654 Bleomycin Proteins 0.000 abstract 4
- 229960001561 bleomycin Drugs 0.000 abstract 4
- OYVAGSVQBOHSSS-UAPAGMARSA-O bleomycin A2 Chemical compound N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC=C(N=1)C=1SC=C(N=1)C(=O)NCCC[S+](C)C)[C@@H](O[C@H]1[C@H]([C@@H](O)[C@H](O)[C@H](CO)O1)O[C@@H]1[C@H]([C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O1)O)C=1N=CNC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C OYVAGSVQBOHSSS-UAPAGMARSA-O 0.000 abstract 4
- 230000003115 biocidal effect Effects 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 150000007649 L alpha amino acids Chemical class 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 150000001370 alpha-amino acid derivatives Chemical class 0.000 abstract 1
- 235000008206 alpha-amino acids Nutrition 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 125000001151 peptidyl group Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Landscapes
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10641980A JPS5731697A (en) | 1980-08-04 | 1980-08-04 | Masked compound and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10641980A JPS5731697A (en) | 1980-08-04 | 1980-08-04 | Masked compound and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5731697A true JPS5731697A (en) | 1982-02-20 |
| JPS6261038B2 JPS6261038B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1987-12-18 |
Family
ID=14433139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10641980A Granted JPS5731697A (en) | 1980-08-04 | 1980-08-04 | Masked compound and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5731697A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
-
1980
- 1980-08-04 JP JP10641980A patent/JPS5731697A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6261038B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1987-12-18 |
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