JPS5464692A - Novel synthesis of peptide derivatives - Google Patents

Novel synthesis of peptide derivatives

Info

Publication number
JPS5464692A
JPS5464692A JP13185977A JP13185977A JPS5464692A JP S5464692 A JPS5464692 A JP S5464692A JP 13185977 A JP13185977 A JP 13185977A JP 13185977 A JP13185977 A JP 13185977A JP S5464692 A JPS5464692 A JP S5464692A
Authority
JP
Japan
Prior art keywords
amino acid
peptide
protease
peptide derivatives
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13185977A
Other languages
Japanese (ja)
Other versions
JPS6027519B2 (en
Inventor
Kazuyuki Morihara
Tatsu Oka
Takeshi Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP52131859A priority Critical patent/JPS6027519B2/en
Publication of JPS5464692A publication Critical patent/JPS5464692A/en
Publication of JPS6027519B2 publication Critical patent/JPS6027519B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To synthesize peptide derivatives using protease.
CONSTITUTION: Peptide derivatives S-A-B-Y, X-A-B-C-OH ro X-A-B-C-Y (X is terminal amino-protecting group, amino acid residue or peptide residue having protected terminal amino group; A is amino acid residue having protease specificity; Y is terminal carboxyl-protecting group; B is amino acid residue having protease specificity; C is amino acid residue, peptide residue) are prepared by reacting (a) an L-amino acid or a peptide derivative X-A-OH with (b) excess or deficient amount of an L-amino acid or a peptide derivative H-B-Y, H-B-C-OH, or H-B-C-Y, in the presence of protease at 20-50°C, pref. 30-40°C, and at a pH optimum to the protease.
COPYRIGHT: (C)1979,JPO&Japio
JP52131859A 1977-11-02 1977-11-02 New synthesis method for peptide derivatives Expired JPS6027519B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP52131859A JPS6027519B2 (en) 1977-11-02 1977-11-02 New synthesis method for peptide derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52131859A JPS6027519B2 (en) 1977-11-02 1977-11-02 New synthesis method for peptide derivatives

Publications (2)

Publication Number Publication Date
JPS5464692A true JPS5464692A (en) 1979-05-24
JPS6027519B2 JPS6027519B2 (en) 1985-06-29

Family

ID=15067779

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52131859A Expired JPS6027519B2 (en) 1977-11-02 1977-11-02 New synthesis method for peptide derivatives

Country Status (1)

Country Link
JP (1) JPS6027519B2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041499A (en) * 1983-08-12 1985-03-05 Asahi Chem Ind Co Ltd Enzymatic synthesis of peptide
EP0303602A1 (en) * 1986-04-10 1989-02-22 Commonwealth Scientific And Industrial Research Organisation Enzymatic synthesis
JP2017513923A (en) * 2014-03-14 2017-06-01 欧詩漫生物股▲ふん▼有限公司Ｏｓｍｕｎ Ｂｉｏｌｏｇｉｃａｌ Ｃｏ．， Ｌｔｄ Method for separating and producing pearl extract from a kind of pearl

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63160598U (en) * 1987-04-07 1988-10-20

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50110093A (en) * 1974-02-09 1975-08-29
JPS50110094A (en) * 1974-02-09 1975-08-29
JPS50140686A (en) * 1974-04-24 1975-11-11
JPS5251092A (en) * 1975-10-23 1977-04-23 Sagami Chem Res Center Method of preparing peptides
JPS5251093A (en) * 1975-10-23 1977-04-23 Sagami Chem Res Center Mthod of preparing peptides
JPS5272885A (en) * 1975-10-23 1977-06-17 Sagami Chem Res Center Preparation of peptide
JPS52108089A (en) * 1976-03-09 1977-09-10 Shionogi & Co Ltd Novel process for synthesis of peptide derivatives
JPS5326394A (en) * 1976-08-24 1978-03-11 Sagami Chem Res Center Preparation of peptide
JPS5326393A (en) * 1976-08-24 1978-03-11 Sagami Chem Res Center Preparation of peptide
JPS5326392A (en) * 1976-08-24 1978-03-11 Sagami Chem Res Center Preparation of peptide

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50110093A (en) * 1974-02-09 1975-08-29
JPS50110094A (en) * 1974-02-09 1975-08-29
JPS50140686A (en) * 1974-04-24 1975-11-11
JPS5251092A (en) * 1975-10-23 1977-04-23 Sagami Chem Res Center Method of preparing peptides
JPS5251093A (en) * 1975-10-23 1977-04-23 Sagami Chem Res Center Mthod of preparing peptides
JPS5272885A (en) * 1975-10-23 1977-06-17 Sagami Chem Res Center Preparation of peptide
JPS52108089A (en) * 1976-03-09 1977-09-10 Shionogi & Co Ltd Novel process for synthesis of peptide derivatives
JPS5326394A (en) * 1976-08-24 1978-03-11 Sagami Chem Res Center Preparation of peptide
JPS5326393A (en) * 1976-08-24 1978-03-11 Sagami Chem Res Center Preparation of peptide
JPS5326392A (en) * 1976-08-24 1978-03-11 Sagami Chem Res Center Preparation of peptide

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041499A (en) * 1983-08-12 1985-03-05 Asahi Chem Ind Co Ltd Enzymatic synthesis of peptide
EP0303602A1 (en) * 1986-04-10 1989-02-22 Commonwealth Scientific And Industrial Research Organisation Enzymatic synthesis
JP2017513923A (en) * 2014-03-14 2017-06-01 欧詩漫生物股▲ふん▼有限公司Ｏｓｍｕｎ Ｂｉｏｌｏｇｉｃａｌ Ｃｏ．， Ｌｔｄ Method for separating and producing pearl extract from a kind of pearl

Also Published As

Publication number Publication date
JPS6027519B2 (en) 1985-06-29

Similar Documents

Publication Publication Date Title
EP0254080A3 (en) Malonic acid derivatives and methods for their synthesis
ES8501364A1 (en) Peptides.
JPS53119844A (en) Optically active amino acid-mandelic acid complexes and theire preparation
JPS5464692A (en) Novel synthesis of peptide derivatives
ES8605769A1 (en) Peptides.
JPS56110661A (en) Preparation of n-benzyloxycarbonyl-l-aspartic acid
JPS5218886A (en) Production of amino acids by fermentation process
ES457563A1 (en) Dipeptide derivatives
EP0438600A4 (en) Enzymes which participate in c-terminal amidation, and production and use thereof
JPS5334716A (en) Preparation of amide amine amphoteric surface active agent
JPS5251092A (en) Method of preparing peptides
JPS5225768A (en) Preparation of novel pentapeptides
GB1533129A (en) Process for producing a peptide in the presence of an enzyme
JPS57118563A (en) Indole derivative and preparation of peptide
JPS5251093A (en) Mthod of preparing peptides
JPS52128290A (en) Preparation of acylpeptides
JPS51115402A (en) Process for preparation of alpha-amino acid
JPS55151555A (en) Proline derivatives and their production
JPS55127353A (en) Gamma-rearrangement of alpha-glutamylpeptide
JPS5519051A (en) Production of adduct of n-benzyloxycarbonyl-l-aspartyl-l- phenylalanine methyl ester to methyl phenylalanate
DE3855751D1 (en) Hypoglycemische peptide
JPS52128291A (en) Synthesis of peptides
JPS5283738A (en) Novel dipeptide derivatives and their salts
JPS5464693A (en) Preparation of peptide derivative
JPS523016A (en) Preparation of high-purity leucine