JPS5731685A - Preparation of 2',3',5'-triacetoxy-5-fluorouridine - Google Patents

Preparation of 2',3',5'-triacetoxy-5-fluorouridine

Info

Publication number
JPS5731685A
JPS5731685A JP10545780A JP10545780A JPS5731685A JP S5731685 A JPS5731685 A JP S5731685A JP 10545780 A JP10545780 A JP 10545780A JP 10545780 A JP10545780 A JP 10545780A JP S5731685 A JPS5731685 A JP S5731685A
Authority
JP
Japan
Prior art keywords
fluorouridine
triacetoxy
expressed
formula
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10545780A
Other languages
Japanese (ja)
Inventor
Takao Takahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daikin Industries Ltd
Original Assignee
Daikin Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daikin Industries Ltd filed Critical Daikin Industries Ltd
Priority to JP10545780A priority Critical patent/JPS5731685A/en
Publication of JPS5731685A publication Critical patent/JPS5731685A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To obtain the titled compound which is a carcinostatic agent in high yield in one stage by reacting the 5,6-dihydro derivative of a 5-fluorouridiane with acetic anhydride.
CONSTITUTION: One mole 5,6-dihydro derivative of a 5-fluorouridine expressed by formula I (R is hydrogen, acyl, alkyl, halogenated acyl or halogenated alkyl) is reacted 3 moles or more acetic anhydride, if necessary in the presence of an acid acceptor, e.g. a trialkylamine or pyridine, at 120°C or below to give 2',3',5'-triacetoxy- 5-fluorouridine expressed by formula II.
COPYRIGHT: (C)1982,JPO&Japio
JP10545780A 1980-07-30 1980-07-30 Preparation of 2',3',5'-triacetoxy-5-fluorouridine Pending JPS5731685A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10545780A JPS5731685A (en) 1980-07-30 1980-07-30 Preparation of 2',3',5'-triacetoxy-5-fluorouridine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10545780A JPS5731685A (en) 1980-07-30 1980-07-30 Preparation of 2',3',5'-triacetoxy-5-fluorouridine

Publications (1)

Publication Number Publication Date
JPS5731685A true JPS5731685A (en) 1982-02-20

Family

ID=14408107

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10545780A Pending JPS5731685A (en) 1980-07-30 1980-07-30 Preparation of 2',3',5'-triacetoxy-5-fluorouridine

Country Status (1)

Country Link
JP (1) JPS5731685A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2630447A1 (en) * 1988-04-21 1989-10-27 Central Glass Co Ltd PROCESS FOR PREPARING DIACYCLE DERIVATIVES OF 2 (PRIME) -DESOXY-5-FLUOROURIDINE VIA A NEW INTERMEDIATE COMPOUND

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2630447A1 (en) * 1988-04-21 1989-10-27 Central Glass Co Ltd PROCESS FOR PREPARING DIACYCLE DERIVATIVES OF 2 (PRIME) -DESOXY-5-FLUOROURIDINE VIA A NEW INTERMEDIATE COMPOUND

Similar Documents

Publication Publication Date Title
JPS5731685A (en) Preparation of 2',3',5'-triacetoxy-5-fluorouridine
JPS56104890A (en) Preparation of organosilane
JPS57163393A (en) Novel anthracyclin derivative and its preparation
ES8307236A1 (en) Process for the preparation of a furan derivative.
JPS55151549A (en) Production of guanidinocaproic ester
JPS5655383A (en) Amizine derivative and its preparation
JPS57163371A (en) Preparation of hydroquinone derivative
JPS56118081A (en) Preparation of 6-methoxy-1,8-naphthyridine
JPS55149257A (en) Novel preparation of isoindoline derivative
JPS5753469A (en) 5-fluorouracil derivative, its preparation and use
JPS56103197A (en) Novel d-glucose derivative and antitumor agent containing the same as active constitutent
JPS57154189A (en) Preparation of cephalosporin derivative
JPS54112848A (en) Preparation of 3beta-hydroxy-24-oxo-5alpha-cholestane-5-ene
JPS5321170A (en) Preparation of branched 2-deoxy-alpha-glycosides
JPS5589284A (en) Preparation of xanthine derivative
JPS5535051A (en) Preparation of naphthostyril
JPS6445392A (en) Production of estradiol derivative
JPS55149256A (en) Novel preparation of isoindoline derivative
JPS567752A (en) Preparation of 2- sulfophenylhydrazino -butane diacid derivative
JPS5793933A (en) Preparation of 2-hydroxy-3-butenoic acid derivative
JPS5547651A (en) Production of sulfoxyimine
JPS55108857A (en) Preparation of 5-fluorouracil derivative
JPS5742652A (en) Preparation of hydroxyphenylacetic acid and catalyst for preparing it
JPS5598177A (en) Novel 3-hydroxyphthalide derivative
JPS54144400A (en) Preparation of rifamycin derivative